Design, Synthesis, and Evaluation of Novel and Selective G‑protein Coupled Receptor 120 (GPR120) Spirocyclic Agonists
Cox, Jason M, Chu, Hong D, Chelliah, Mariappan V, Debenham, John S, Eagen, Keith, Lan, Ping, Lombardo, Matthew, London, Clare, Plotkin, Michael A, Shah, Unmesh, Sun, Zhongxiang, Vaccaro, Henry M, Venkatraman, Srikanth, Suzuki, Takao, Wang, Nengxue, Ashley, Eric R, Crespo, Alejandro, Madeira, Maria, Leung, Dennis H, Alleyne, Candice, Ogawa, Aimie M, Souza, Sarah, Thomas-Fowlkes, Brande, Di Salvo, Jerry, Weinglass, Adam, Kirkland, Melissa, Pachanski, Michele, Powles, Mary Ann, Tozzo, Effie, Akiyama, Taro E, Ujjainwalla, Feroze, Tata, James R, Sinz, Christopher J
Published in ACS medicinal chemistry letters (12.01.2017)
Published in ACS medicinal chemistry letters (12.01.2017)
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Discovery of a nortropanol derivative as a potent and orally active GPR119 agonist for type 2 diabetes
Xia, Yan, Chackalamannil, Samuel, Greenlee, William J., Jayne, Charles, Neustadt, Bernard, Stamford, Andrew, Vaccaro, Henry, Xu, Xiaoying (Lucy), Baker, Hana, O’Neill, Kim, Woods, Morgan, Hawes, Brian, Kowalski, Tim
Published in Bioorganic & medicinal chemistry letters (01.06.2011)
Published in Bioorganic & medicinal chemistry letters (01.06.2011)
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Tetrahydroquinoline sulfonamides as vasopressin 1b receptor anatgonists
Scott, Jack D., Miller, Michael W., Li, Sarah W., Lin, Sue-Ing, Vaccaro, Henry A., Hong, Liwu, Mullins, Deborra E., Guzzi, Mario, Weinstein, Jay, Hodgson, Robert A., Varty, Geoffrey B., Stamford, Andrew W., Chan, Tin-Yau, McKittrick, Brian A., Greenlee, William J., Priestley, Tony, Parker, Eric M.
Published in Bioorganic & medicinal chemistry letters (01.11.2009)
Published in Bioorganic & medicinal chemistry letters (01.11.2009)
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2,6-Disubstituted N-arylsulfonyl piperidines as γ-secretase inhibitors
Pissarnitski, Dmitri A., Asberom, Theodros, Bara, Thomas A., Buevich, Alex V., Clader, John W., Greenlee, William J., Guzik, Henry S., Josien, Hubert B., Li, Wei, McEwan, Michael, McKittrick, Brian A., Nechuta, Terry L., Parker, Eric M., Sinning, Lisa, Smith, Elizabeth M., Song, Lixin, Vaccaro, Henry A., Voigt, Johannes H., Zhang, Lili, Zhang, Qi, Zhao, Zhiqiang
Published in Bioorganic & medicinal chemistry letters (2007)
Published in Bioorganic & medicinal chemistry letters (2007)
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Synthesis and Evaluation of Polycyclic Pyrazolo[3,4-d]pyrimidines as PDE1 and PDE5 cGMP Phosphodiesterase Inhibitors
Xia, Yan, Chackalamannil, Samuel, Czarniecki, Michael, Tsai, Hsingan, Vaccaro, Henry, Cleven, Renee, Cook, John, Fawzi, Ahmad, Watkins, Robert, Zhang, Hongtao
Published in Journal of medicinal chemistry (19.12.1997)
Published in Journal of medicinal chemistry (19.12.1997)
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Phyllanthoside-phyllanthostatin synthetic studies. 8. Total synthesis of (+)-phyllanthoside. Development of the Mitsunobu glycosyl ester protocol
Smith, Amos B, Rivero, Ralph A, Hale, Karl J, Vaccaro, Henry A
Published in Journal of the American Chemical Society (01.03.1991)
Published in Journal of the American Chemical Society (01.03.1991)
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Total synthesis of (.+-.)-breynolide, an aglycon derivative of the orally active hypocholesterolemic agent breynin A
Smith, Amos B, Empfield, James R, Rivero, Ralph A, Vaccaro, Henry A, Duan, James J. W, Sulikowski, Michelle M
Published in Journal of the American Chemical Society (01.11.1992)
Published in Journal of the American Chemical Society (01.11.1992)
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Discovery of 8‑Amino-imidazo[1,5‑a]pyrazines as Reversible BTK Inhibitors for the Treatment of Rheumatoid Arthritis
Liu, Jian, Guiadeen, Deodial, Krikorian, Arto, Gao, Xiaolei, Wang, James, Boga, Sobhana Babu, Alhassan, Abdul-Basit, Yu, Younong, Vaccaro, Henry, Liu, Shilan, Yang, Chundao, Wu, Hao, Cooper, Alan, de Man, Jos, Kaptein, Allard, Maloney, Kevin, Hornak, Viktor, Gao, Ying-Duo, Fischmann, Thierry O, Raaijmakers, Hans, Vu-Pham, Diep, Presland, Jeremy, Mansueto, My, Xu, Zangwei, Leccese, Erica, Zhang-Hoover, Jie, Knemeyer, Ian, Garlisi, Charles G, Bays, Nathan, Stivers, Peter, Brandish, Philip E, Hicks, Alexandra, Kim, Ronald, Kozlowski, Joseph A
Published in ACS medicinal chemistry letters (11.02.2016)
Published in ACS medicinal chemistry letters (11.02.2016)
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I. Novel HCV NS5B polymerase inhibitors: Discovery of indole 2-carboxylic acids with C3-heterocycles
Anilkumar, Gopinadhan N., Lesburg, Charles A., Selyutin, Oleg, Rosenblum, Stuart B., Zeng, Qingbei, Jiang, Yueheng, Chan, Tin-Yau, Pu, Haiyan, Vaccaro, Henry, Wang, Li, Bennett, Frank, Chen, Kevin X., Duca, Jose, Gavalas, Stephen, Huang, Yuhua, Pinto, Patrick, Sannigrahi, Mousumi, Velazquez, Francisco, Venkatraman, Srikanth, Vibulbhan, Bancha, Agrawal, Sony, Butkiewicz, Nancy, Feld, Boris, Ferrari, Eric, He, Zhiqing, Jiang, Chuan-kui, Palermo, Robert E., Mcmonagle, Patricia, Huang, H.-C., Shih, Neng-Yang, Njoroge, George, Kozlowski, Joseph A.
Published in Bioorganic & medicinal chemistry letters (15.09.2011)
Published in Bioorganic & medicinal chemistry letters (15.09.2011)
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Phyllanthoside-phyllanthostatin synthetic studies. 9. Total syntheses of (-)-phyllanthostatin 1, (+)-phyllanthostatin 2, and (+)-phyllanthostatin 3
Smith, Amos B, Hale, Karl J, Vaccaro, Henry A, Rivero, Ralph A
Published in Journal of the American Chemical Society (01.03.1991)
Published in Journal of the American Chemical Society (01.03.1991)
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Iminopyrimidinones: A novel pharmacophore for the development of orally active renin inhibitors
McKittrick, Brian A., Caldwell, John P., Bara, Thomas, Boykow, George, Chintala, Madhu, Clader, John, Czarniecki, Michael, Courneya, Brandy, Duffy, Ruth, Fleming, Linda, Giessert, Rachel, Greenlee, William J., Heap, Charles, Hong, Liwu, Huang, Ying, Iserloh, Ulrich, Josien, Hubert, Khan, Tanweer, Korfmacher, Walter, Liang, Xian, Mazzola, Robert, Mitra, Soumya, Moore, Kristina, Orth, Peter, Rajagopalan, Murali, Roy, Sudipta, Sakwa, Samuel, Strickland, Corey, Vaccaro, Henry, Voigt, Johannes, Wang, Hongwu, Wong, Jesse, Zhang, Rumin, Zych, Andrew
Published in Bioorganic & medicinal chemistry letters (01.04.2015)
Published in Bioorganic & medicinal chemistry letters (01.04.2015)
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Discovery of a series of potent arylthiadiazole H 3 antagonists
Xiao, Dong, Palani, Anandan, Sofolarides, Michael, Huang, Ying, Aslanian, Robert, Vaccaro, Henry, Hong, Liwu, McKittrick, Brian, West, Robert E., Williams, Shirley M., Wu, Ren-Long, Hwa, Joyce, Sondey, Christopher, Lachowicz, Jean
Published in Bioorganic & medicinal chemistry letters (15.01.2011)
Published in Bioorganic & medicinal chemistry letters (15.01.2011)
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The discovery of novel tartrate-based TNF-α converting enzyme (TACE) inhibitors
Rosner, Kristin E., Guo, Zhuyan, Orth, Peter, Shipps, Gerald W., Belanger, David B., Chan, Tin Yau, Curran, Patrick J., Dai, Chaoyang, Deng, Yongqi, Girijavallabhan, Vinay M., Hong, Liwu, Lavey, Brian J., Lee, Joe F., Li, Dansu, Liu, Zhidan, Popovici-Muller, Janeta, Ting, Pauline C., Vaccaro, Henry, Wang, Li, Wang, Tong, Yu, Wensheng, Zhou, Guowei, Niu, Xiaoda, Sun, Jing, Kozlowski, Joseph A., Lundell, Daniel J., Madison, Vincent, McKittrick, Brian, Piwinski, John J., Shih, Neng -Yang, Arshad Siddiqui, M., Strickland, Corey O.
Published in Bioorganic & medicinal chemistry letters (01.02.2010)
Published in Bioorganic & medicinal chemistry letters (01.02.2010)
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Discovery of a series of potent arylthiadiazole H sub(3) antagonists
Xiao, Dong, Palani, Anandan, Sofolarides, Michael, Huang, Ying, Aslanian, Robert, Vaccaro, Henry, Hong, Liwu, McKittrick, Brian, West, Robert E, Williams, Shirley M, Wu, Ren-Long, Hwa, Joyce, Sondey, Christopher, Lachowicz, Jean
Published in Bioorganic & medicinal chemistry letters (15.01.2011)
Published in Bioorganic & medicinal chemistry letters (15.01.2011)
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Discovery of a series of potent arylthiadiazole H₃ antagonists
Xiao, Dong, Palani, Anandan, Sofolarides, Michael, Huang, Ying, Aslanian, Robert, Vaccaro, Henry, Hong, Liwu, McKittrick, Brian, West, Robert E., Jr, Williams, Shirley M, Wu, Ren-Long, Hwa, Joyce, Sondey, Christopher, Lachowicz, Jean
Published in Bioorganic & medicinal chemistry letters (2011)
Published in Bioorganic & medicinal chemistry letters (2011)
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Hydrogen-Bonding Motifs and Proton-Transfer Dynamics in Electronically Excited 6‑Hydroxy-2-formylfulvene
Vealey, Zachary N, Foguel, Lidor, Vaccaro, Patrick H
Published in The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory (01.08.2019)
Published in The journal of physical chemistry. A, Molecules, spectroscopy, kinetics, environment, & general theory (01.08.2019)
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