Rho-kinase inhibitor coupled to peptide-modified albumin carrier reduces portal pressure and increases renal perfusion in cirrhotic rats
Klein, Sabine, Frohn, Franziska, Magdaleno, Fernando, Reker-Smit, Catharina, Schierwagen, Robert, Schierwagen, Irela, Uschner, Frank Erhard, van Dijk, Fransien, Fürst, Dieter O., Djudjaj, Sonja, Boor, Peter, Poelstra, Klaas, Beljaars, Leonie, Trebicka, Jonel
Published in Scientific reports (19.02.2019)
Published in Scientific reports (19.02.2019)
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Journal Article
Hepatic inflammasome activation as origin of Interleukin-1α and Interleukin-1β in liver cirrhosis
Praktiknjo, Michael, Schierwagen, Robert, Monteiro, Sofia, Ortiz, Cristina, Uschner, Frank Erhard, Jansen, Christian, Claria, Joan, Trebicka, Jonel
Published in Gut (01.09.2021)
Published in Gut (01.09.2021)
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Journal Article
Circulating microbiome in blood of different circulatory compartments
Schierwagen, Robert, Alvarez-Silva, Camila, Madsen, Mette Simone Aae, Kolbe, Carl Christian, Meyer, Carsten, Thomas, Daniel, Uschner, Frank Erhard, Magdaleno, Fernando, Jansen, Christian, Pohlmann, Alessandra, Praktiknjo, Michael, Hischebeth, Gunnar T, Molitor, Ernst, Latz, Eicke, Lelouvier, Benjamin, Trebicka, Jonel, Arumugam, Manimozhiyan
Published in Gut (01.03.2019)
Published in Gut (01.03.2019)
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Journal Article
Differential inflammasome activation predisposes to acute-on-chronic liver failure in human and experimental cirrhosis with and without previous decompensation
Monteiro, Sofia, Grandt, Josephine, Uschner, Frank Erhard, Kimer, Nina, Madsen, Jan Lysgård, Schierwagen, Robert, Klein, Sabine, Welsch, Christoph, Schäfer, Liliana, Jansen, Christian, Claria, Joan, Alcaraz-Quiles, José, Arroyo, Vicente, Moreau, Richard, Fernandez, Javier, Bendtsen, Flemming, Mehta, Gautam, Gluud, Lise Lotte, Møller, Søren, Praktiknjo, Michael, Trebicka, Jonel
Published in Gut (01.02.2021)
Published in Gut (01.02.2021)
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Journal Article
Role of portal venous platelet activation in patients with decompensated cirrhosis and TIPS
Queck, Alexander, Carnevale, Roberto, Uschner, Frank Erhard, Schierwagen, Robert, Klein, Sabine, Jansen, Christian, Meyer, Carsten, Praktiknjo, Michael, Thomas, Daniel, Strassburg, Christian, Zeuzem, Stefan, Violi, Francesco, Trebicka, Jonel
Published in Gut (01.08.2020)
Published in Gut (01.08.2020)
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Journal Article
Two-dimensional shear wave elastography predicts survival in advanced chronic liver disease
Trebicka, Jonel, Gu, Wenyi, de Ledinghen, Victor, Aubé, Christophe, Krag, Aleksander, Praktiknjo, Michael, Castera, Laurent, Dumortier, Jerome, Bauer, David Josef Maria, Friedrich-Rust, Mireen, Pol, Stanislas, Grgurevic, Ivica, Zheng, Rongqin, Francque, Sven, Gottfriedovà, Halima, Mustapic, Sanda, Sporea, Ioan, Berzigotti, Annalisa, Uschner, Frank Erhard, Simbrunner, Benedikt, Ronot, Maxime, Cassinotto, Christophe, Kjaergaard, Maria, Andrade, Filipe, Schulz, Martin, Semmler, Georg, Drinkovic, Ida Tjesic, Chang, Johannes, Brol, Maximilian Joseph, Rautou, Pierre Emmanuel, Vanwolleghem, Thomas, Strassburg, Christian P, Boursier, Jerome, Ferstl, Philip Georg, Rasmussen, Ditlev Nytoft, Reiberger, Thomas, Vilgrain, Valerie, Guibal, Aymeric, Guillaud, Olivier, Zeuzem, Stefan, Vassord, Camille, Lu, Xue, Vonghia, Luisa, Senkerikova, Renata, Popescu, Alina, Margini, Cristina, Wang, Wenping, Thiele, Maja, Jansen, Chrisitan
Published in Gut (01.02.2022)
Published in Gut (01.02.2022)
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Journal Article
Sympathetic nervous activation, mitochondrial dysfunction and outcome in acutely decompensated cirrhosis: the metabolomic prognostic models (CLIF-C MET)
Weiss, Emmanuel, de la Peña-Ramirez, Carlos, Aguilar, Ferran, Lozano, Juan-Jose, Sánchez-Garrido, Cristina, Sierra, Patricia, Martin, Pedro Izquierdo-Bueno, Diaz, Juan Manuel, Fenaille, François, Castelli, Florence A, Gustot, Thierry, Laleman, Wim, Albillos, Agustín, Alessandria, Carlo, Domenicali, Marco, Caraceni, Paolo, Piano, Salvatore, Saliba, Faouzi, Zeuzem, Stefan, Gerbes, Alexander L, Wendon, Julia A, Jansen, Christian, Gu, Wenyi, Papp, Maria, Mookerjee, Raj, Gambino, Carmine Gabriele, Jiménez, Cesar, Giovo, Ilaria, Zaccherini, Giacomo, Merli, Manuela, Putignano, Antonella, Uschner, Frank Erhard, Berg, Thomas, Bruns, Tony, Trautwein, Christian, Zipprich, Alexander, Bañares, Rafael, Presa, José, Genesca, Joan, Vargas, Victor, Fernández, Javier, Bernardi, Mauro, Angeli, Paolo, Jalan, Rajiv, Claria, Joan, Junot, Christophe, Moreau, Richard, Trebicka, Jonel, Arroyo, Vicente
Published in Gut (01.08.2023)
Published in Gut (01.08.2023)
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Journal Article
Janus-kinase-2 relates directly to portal hypertension and to complications in rodent and human cirrhosis
Klein, Sabine, Rick, Johanna, Lehmann, Jennifer, Schierwagen, Robert, Schierwagen, Irela Gretchen, Verbeke, Len, Hittatiya, Kanishka, Uschner, Frank Erhard, Manekeller, Steffen, Strassburg, Christian P, Wagner, Kay-Uwe, Sayeski, Peter P, Wolf, Dominik, Laleman, Wim, Sauerbruch, Tilman, Trebicka, Jonel
Published in Gut (01.01.2017)
Published in Gut (01.01.2017)
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Journal Article
The soluble guanylate cyclase stimulator riociguat reduces fibrogenesis and portal pressure in cirrhotic rats
Schwabl, Philipp, Brusilovskaya, Ksenia, Supper, Paul, Bauer, David, Königshofer, Philipp, Riedl, Florian, Hayden, Hubert, Fuchs, Claudia Daniela, Stift, Judith, Oberhuber, Georg, Aschauer, Stefan, Bonderman, Diana, Gnad, Thorsten, Pfeifer, Alexander, Uschner, Frank Erhard, Trebicka, Jonel, Rohr-Udilova, Nataliya, Podesser, Bruno Karl, Peck-Radosavljevic, Markus, Trauner, Michael, Reiberger, Thomas
Published in Scientific reports (19.06.2018)
Published in Scientific reports (19.06.2018)
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Journal Article
Terlipressin therapy is associated with increased risk of colonisation with multidrug‐resistant bacteria in patients with decompensated cirrhosis
Mücke, Marcus M., Hernández‐Tejero, María, Gu, Wenyi, Kuhn, Michael, Janz, Malte, Keller, Marisa I., Fullam, Anthony, Altepeter, Laura, Mücke, Victoria T., Finkelmeier, Fabian, Schwarzkopf, Katharina M., Cremonese, Carla, Hunyady, Peter‐Merton, Heilani, Myriam W., Uschner, Frank Erhard, Schierwagen, Robert, Brol, Maximilian J., Fischer, Julia, Klein, Sabine, Peiffer, Kai‐Henrik, Hogardt, Michael, Shoaie, Saeed, Coenraad, Minneke J., Bojunga, Jörg, Arroyo, Vicente, Zeuzem, Stefan, Kempf, Volkhard A. J., Welsch, Christoph, Laleman, Wim, Bork, Peer, Fernandez, Javier, Trebicka, Jonel
Published in Alimentary pharmacology & therapeutics (01.04.2024)
Published in Alimentary pharmacology & therapeutics (01.04.2024)
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Journal Article
Variation in Bile Microbiome by the Etiology of Cholestatic Liver Disease
Tyc, Olaf, Jansen, Christian, Schierwagen, Robert, Uschner, Frank Erhard, Israelsen, Mads, Klein, Sabine, Ortiz, Cristina, Strassburg, Christian P., Zeuzem, Stefan, Gu, Wenyi, Torres, Sandra, Praktiknjo, Michael, Kersting, Stephan, Langheinrich, Melanie, Nattermann, Jacob, Servant, Florence, Arumugam, Manimozhiyan, Krag, Aleksander, Lelouvier, Benjamin, Weismüller, Tobias J., Trebicka, Jonel
Published in Liver transplantation (01.12.2020)
Published in Liver transplantation (01.12.2020)
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Journal Article
The Role of Hypoxia-Inducible Factor 1 Alpha in Acute-on-Chronic Liver Failure
Mücke, Marcus M, El Bali, Nihad, Schwarzkopf, Katharina M, Uschner, Frank Erhard, Kraus, Nico, Eberle, Larissa, Mücke, Victoria Therese, Bein, Julia, Beyer, Sandra, Wild, Peter J, Schierwagen, Robert, Klein, Sabine, Zeuzem, Stefan, Welsch, Christoph, Trebicka, Jonel, Brieger, Angela
Published in International journal of molecular sciences (01.02.2024)
Published in International journal of molecular sciences (01.02.2024)
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Journal Article
TGR(mREN2)27 rats develop non-alcoholic fatty liver disease-associated portal hypertension responsive to modulations of Janus-kinase 2 and Mas receptor
Klein, Sabine, Kleine, Carola-Ellen, Pieper, Andrea, Granzow, Michaela, Gautsch, Sebastian, Himmit, Mimoun, Kahrmann, Katharina, Schierwagen, Robert, Uschner, Frank Erhard, Magdaleno, Fernando, Naoum, Maria Eleni, Kristiansen, Glen, Walther, Thomas, Bader, Michael, Sauerbruch, Tilman, Trebicka, Jonel
Published in Scientific reports (12.08.2019)
Published in Scientific reports (12.08.2019)
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Journal Article
Short-Term Western Diet Aggravates Non-Alcoholic Fatty Liver Disease (NAFLD) With Portal Hypertension in TGR(mREN2)27 Rats
Cremonese, Carla, Schierwagen, Robert, Uschner, Frank Erhard, Torres, Sandra, Tyc, Olaf, Ortiz, Cristina, Schulz, Martin, Queck, Alexander, Kristiansen, Glen, Bader, Michael, Sauerbruch, Tilman, Weiskirchen, Ralf, Walther, Thomas, Trebicka, Jonel, Klein, Sabine
Published in International journal of molecular sciences (07.05.2020)
Published in International journal of molecular sciences (07.05.2020)
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Journal Article
Recent Advances in Practical Methods for Liver Cell Biology: A Short Overview
Torres, Sandra, Abdullah, Zeinab, Brol, Maximilian J, Hellerbrand, Claus, Fernandez, Mercedes, Fiorotto, Romina, Klein, Sabine, Königshofer, Philipp, Liedtke, Christian, Lotersztajn, Sophie, Nevzorova, Yulia A, Schierwagen, Robert, Reiberger, Thomas, Uschner, Frank Erhard, Tacke, Frank, Weiskirchen, Ralf, Trebicka, Jonel
Published in International journal of molecular sciences (16.03.2020)
Published in International journal of molecular sciences (16.03.2020)
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Journal Article
Pathophysiological role of prostanoids in coagulation of the portal venous system in liver cirrhosis
Queck, Alexander, Thomas, Dominique, Jansen, Christian, Schreiber, Yannick, Rüschenbaum, Sabrina, Praktiknjo, Michael, Schwarzkopf, Katharina Maria, Mücke, Marcus Maximilian, Schierwagen, Robert, Uschner, Frank Erhard, Meyer, Carsten, Clària, Joan, Zeuzem, Stefan, Geisslinger, Gerd, Trebicka, Jonel, Lange, Christian Markus
Published in PloS one (23.10.2019)
Published in PloS one (23.10.2019)
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Journal Article
Novel Rat Model of Repetitive Portal Venous Embolization Mimicking Human Non-Cirrhotic Idiopathic Portal Hypertension
Klein, Sabine, Hinüber, Christian, Hittatiya, Kanishka, Schierwagen, Robert, Uschner, Frank Erhard, Strassburg, Christian P, Fischer, Hans-Peter, Spengler, Ulrich, Trebicka, Jonel
Published in PloS one (02.09.2016)
Published in PloS one (02.09.2016)
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Journal Article
Baseline Presence of NAFLD Predicts Weight Loss after Gastric Bypass Surgery for Morbid Obesity
Rheinwalt, Karl Peter, Drebber, Uta, Schierwagen, Robert, Klein, Sabine, Neumann, Ulf Peter, Ulmer, Tom Florian, Plamper, Andreas, Kroh, Andreas, Schipper, Sandra, Odenthal, Margarete, Uschner, Frank Erhard, Lingohr, Philipp, Trebicka, Jonel, Brol, Maximilian Joseph
Published in Journal of clinical medicine (26.10.2020)
Published in Journal of clinical medicine (26.10.2020)
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Journal Article
Decompensated MASH-Cirrhosis Model by Acute and Toxic Effects of Phenobarbital
Kraus, Nico, Uschner, Frank Erhard, Moeslein, Magnus, Schierwagen, Robert, Gu, Wenyi, Brol, Maximilian Joseph, Fürst, Eike, Grünewald, Inga, Lotersztajn, Sophie, Rautou, Pierre-Emmanuel, Duran-Güell, Marta, Flores Costa, Roger, Clària, Joan, Trebicka, Jonel, Klein, Sabine
Published in Cells (Basel, Switzerland) (16.10.2024)
Published in Cells (Basel, Switzerland) (16.10.2024)
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Journal Article
Myostatin is associated with the presence and development of acute-on-chronic liver failure
Ruiz-Margáin, Astrid, Pohlmann, Alessandra, Lanzerath, Silke, Langheinrich, Melanie, Campos-Murguía, Alejandro, Román-Calleja, Berenice M., Schierwagen, Robert, Klein, Sabine, Uschner, Frank Erhard, Brol, Maximilian Joseph, Torre-Delgadillo, Aldo, Flores-García, Nayelli C., Praktiknjo, Michael, Macías Rodríguez, Ricardo U., Trebicka, Jonel
Published in JHEP reports (01.08.2023)
Published in JHEP reports (01.08.2023)
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Journal Article