Endogenous Retrotransposition Activates Oncogenic Pathways in Hepatocellular Carcinoma
Shukla, Ruchi, Upton, Kyle R., Muñoz-Lopez, Martin, Gerhardt, Daniel J., Fisher, Malcolm E., Nguyen, Thu, Brennan, Paul M., Baillie, J. Kenneth, Collino, Agnese, Ghisletti, Serena, Sinha, Shruti, Iannelli, Fabio, Radaelli, Enrico, Dos Santos, Alexandre, Rapoud, Delphine, Guettier, Catherine, Samuel, Didier, Natoli, Gioacchino, Carninci, Piero, Ciccarelli, Francesca D., Garcia-Perez, Jose Luis, Faivre, Jamila, Faulkner, Geoffrey J.
Published in Cell (28.03.2013)
Published in Cell (28.03.2013)
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Ubiquitous L1 Mosaicism in Hippocampal Neurons
Upton, Kyle R., Gerhardt, Daniel J., Jesuadian, J. Samuel, Richardson, Sandra R., Sánchez-Luque, Francisco J., Bodea, Gabriela O., Ewing, Adam D., Salvador-Palomeque, Carmen, van der Knaap, Marjo S., Brennan, Paul M., Vanderver, Adeline, Faulkner, Geoffrey J.
Published in Cell (09.04.2015)
Published in Cell (09.04.2015)
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Somatic retrotransposition alters the genetic landscape of the human brain
Baillie, J. Kenneth, Barnett, Mark W., Upton, Kyle R., Gerhardt, Daniel J., Richmond, Todd A., De Sapio, Fioravante, Brennan, Paul M., Rizzu, Patrizia, Smith, Sarah, Fell, Mark, Talbot, Richard T., Gustincich, Stefano, Freeman, Thomas C., Mattick, John S., Hume, David A., Heutink, Peter, Carninci, Piero, Jeddeloh, Jeffrey A., Faulkner, Geoffrey J.
Published in Nature (London) (30.10.2011)
Published in Nature (London) (30.10.2011)
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Extensive somatic L1 retrotransposition in colorectal tumors
Solyom, Szilvia, Ewing, Adam D, Rahrmann, Eric P, Doucet, Tara, Nelson, Heather H, Burns, Michael B, Harris, Reuben S, Sigmon, David F, Casella, Alex, Erlanger, Bracha, Wheelan, Sarah, Upton, Kyle R, Shukla, Ruchi, Faulkner, Geoffrey J, Largaespada, David A, Kazazian, Jr, Haig H
Published in Genome research (01.12.2012)
Published in Genome research (01.12.2012)
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High glucose levels increase influenza-associated damage to the pulmonary epithelial-endothelial barrier
Hulme, Katina D, Yan, Limin, Marshall, Rebecca J, Bloxham, Conor J, Upton, Kyle R, Hasnain, Sumaira Z, Bielefeldt-Ohmann, Helle, Loh, Zhixuan, Ronacher, Katharina, Chew, Keng Yih, Gallo, Linda A, Short, Kirsty R
Published in eLife (22.07.2020)
Published in eLife (22.07.2020)
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A paucigranulocytic asthma host environment promotes the emergence of virulent influenza viral variants
Hulme, Katina D, Karawita, Anjana C, Pegg, Cassandra, Bunte, Myrna Jm, Bielefeldt-Ohmann, Helle, Bloxham, Conor J, Van den Hoecke, Silvie, Setoh, Yin Xiang, Vrancken, Bram, Spronken, Monique, Steele, Lauren E, Verzele, Nathalie Aj, Upton, Kyle R, Khromykh, Alexander A, Chew, Keng Yih, Sukkar, Maria, Phipps, Simon, Short, Kirsty R
Published in eLife (16.02.2021)
Published in eLife (16.02.2021)
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Author Correction: Reprogramming triggers endogenous L1 and Alu retrotransposition in human induced pluripotent stem cells
Klawitter, Sabine, Fuchs, Nina V., Upton, Kyle R., Muñoz-Lopez, Martin, Shukla, Ruchi, Wang, Jichang, Garcia-Cañadas, Marta, Lopez-Ruiz, Cesar, Gerhardt, Daniel J., Sebe, Attila, Grabundzija, Ivana, Merkert, Sylvia, Gerdes, Patricia, Pulgarin, J. Andres, Bock, Anja, Held, Ulrike, Witthuhn, Anett, Haase, Alexandra, Sarkadi, Balázs, Löwer, Johannes, Wolvetang, Ernst J., Martin, Ulrich, Ivics, Zoltán, Izsvák, Zsuzsanna, Garcia-Perez, Jose L., Faulkner, Geoffrey J., Schumann, Gerald G.
Published in Nature communications (19.12.2018)
Published in Nature communications (19.12.2018)
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Evidence for L1-associated DNA rearrangements and negligible L1 retrotransposition in glioblastoma multiforme
Carreira, Patricia E, Ewing, Adam D, Li, Guibo, Schauer, Stephanie N, Upton, Kyle R, Fagg, Allister C, Morell, Santiago, Kindlova, Michaela, Gerdes, Patricia, Richardson, Sandra R, Li, Bo, Gerhardt, Daniel J, Wang, Jun, Brennan, Paul M, Faulkner, Geoffrey J
Published in Mobile DNA (11.11.2016)
Published in Mobile DNA (11.11.2016)
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Pleiotropic Impacts of Macrophage and Microglial Deficiency on Development in Rats with Targeted Mutation of the Csf1r Locus
Pridans, Clare, Raper, Anna, Davis, Gemma M, Alves, Joana, Sauter, Kristin A, Lefevre, Lucas, Regan, Tim, Meek, Stephen, Sutherland, Linda, Thomson, Alison J, Clohisey, Sara, Bush, Stephen J, Rojo, Rocío, Lisowski, Zofia M, Wallace, Robert, Grabert, Kathleen, Upton, Kyle R, Tsai, Yi Ting, Brown, Deborah, Smith, Lee B, Summers, Kim M, Mabbott, Neil A, Piccardo, Pedro, Cheeseman, Michael T, Burdon, Tom, Hume, David A
Published in The Journal of immunology (1950) (01.11.2018)
Published in The Journal of immunology (1950) (01.11.2018)
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Journal Article
Reprogramming triggers endogenous L1 and Alu retrotransposition in human induced pluripotent stem cells
Klawitter, Sabine, Fuchs, Nina V., Upton, Kyle R., Muñoz-Lopez, Martin, Shukla, Ruchi, Wang, Jichang, Garcia-Cañadas, Marta, Lopez-Ruiz, Cesar, Gerhardt, Daniel J., Sebe, Attila, Grabundzija, Ivana, Merkert, Sylvia, Gerdes, Patricia, Pulgarin, J. Andres, Bock, Anja, Held, Ulrike, Witthuhn, Anett, Haase, Alexandra, Sarkadi, Balázs, Löwer, Johannes, Wolvetang, Ernst J., Martin, Ulrich, Ivics, Zoltán, Izsvák, Zsuzsanna, Garcia-Perez, Jose L., Faulkner, Geoffrey J., Schumann, Gerald G.
Published in Nature communications (08.01.2016)
Published in Nature communications (08.01.2016)
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L1 Retrotransposon Heterogeneity in Ovarian Tumor Cell Evolution
Nguyen, Thu H.M., Carreira, Patricia E., Sanchez-Luque, Francisco J., Schauer, Stephanie N., Fagg, Allister C., Richardson, Sandra R., Davies, Claire M., Jesuadian, J. Samuel, Kempen, Marie-Jeanne H.C., Troskie, Robin-Lee, James, Cini, Beaven, Elizabeth A., Wallis, Tristan P., Coward, Jermaine I.G., Chetty, Naven P., Crandon, Alexander J., Venter, Deon J., Armes, Jane E., Perrin, Lewis C., Hooper, John D., Ewing, Adam D., Upton, Kyle R., Faulkner, Geoffrey J.
Published in Cell reports (Cambridge) (26.06.2018)
Published in Cell reports (Cambridge) (26.06.2018)
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Is somatic retrotransposition a parasitic or symbiotic phenomenon?
Upton, Kyle R., Baillie, J. Kenneth, Faulkner, Geoffrey J.
Published in Mobile genetic elements (01.11.2011)
Published in Mobile genetic elements (01.11.2011)
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Journal Article
Correction: Pleiotropic Impacts of Macrophage and Microglial Deficiency on Development in Rats with Targeted Mutation of the Csf1r Locus
Pridans, Clare, Raper, Anna, Davis, Gemma M, Alves, Joana, Sauter, Kristin A, Lefevre, Lucas, Regan, Tim, Meek, Stephen, Sutherland, Linda, Thomson, Alison J, Clohisey, Sara, Bush, Stephen J, Rojo, Rocío, Lisowski, Zofia M, Wallace, Robert, Grabert, Kathleen, Upton, Kyle R, Tsai, Yi Ting, Brown, Deborah, Smith, Lee B, Summers, Kim M, Mabbott, Neil A, Piccardo, Pedro, Cheeseman, Michael T, Burdon, Tom, Hume, David A
Published in The Journal of immunology (1950) (01.06.2019)
Published in The Journal of immunology (1950) (01.06.2019)
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Reprogramming of somatic cells after fusion with induced pluripotent stem cells and nuclear transfer embryonic stem cells
Sumer, Huseyin, Jones, Karen L, Liu, Jun, Heffernan, Corey, Tat, Pollyanna A, Upton, Kyle R, Verma, Paul J
Published in Stem cells and development (01.02.2010)
Published in Stem cells and development (01.02.2010)
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Somatic retrotransposition alters the genetic landscape of the human brain
Baillie, J. Kenneth, Barnett, Mark W, Upton, Kyle R, Gerhardt, Daniel J, Richmond, Todd A, De Sapio, Fioravante, Brennan, Paul, Rizzu, Patrizia, Smith, Sarah, Fell, Mark, Talbot, Richard T, Gustincich, Stefano, Freeman, Thomas C, Mattick, John S, Hume, David A, Heutink, Peter, Carninci, Piero, Jeddeloh, Jeffrey A, Faulkner, Geoffrey J
Published in Nature (London) (24.11.2011)
Published in Nature (London) (24.11.2011)
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