Differential expression of CCR8 in tumors versus normal tissue allows specific depletion of tumor-infiltrating T regulatory cells by GS-1811, a novel Fc-optimized anti-CCR8 antibody
Weaver, Jessica D., Stack, Edward C., Buggé, Joshua A., Hu, Changyun, McGrath, Lara, Mueller, Amy, Wong, Masie, Klebanov, Boris, Rahman, Tanzila, Kaufman, Rosemary, Fregeau, Christine, Spaulding, Vikki, Priess, Michelle, Legendre, Kristen, Jaffe, Sarah, Upadhyay, Dhruvkumar, Singh, Anirudh, Xu, Chang-Ai, Krukenberg, Kristin, Zhang, Yan, Ezzyat, Yassine, Saddier Axe, Dorothée, Kuhne, Michelle R., Meehl, Michael A., Shaffer, Donald R., Weist, Brian M., Wiederschain, Dmitri, Depis, Fabien, Gostissa, Monica
Published in Oncoimmunology (31.12.2022)
Published in Oncoimmunology (31.12.2022)
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Abstract 4532: Preclinical evaluation of JTX-1811, an anti-CCR8 antibody with enhanced ADCC activity, for preferential depletion of tumor-infiltrating regulatory T cells
Dépis, Fabien, Hu, Changyun, Weaver, Jessica, McGrath, Lara, Klebanov, Boris, Buggé, Joshua, Umiker, Ben, Fregeau, Christine, Upadhyay, Dhruvkumar, Singh, Anirudh, Xu, Chang-Ai, Spaulding, Vikki, Priess, Michelle, Wong, Masie, Naheed, Seema, Zhang, Yan, Legendre, Kristin, Stack, Edward C., Mora, Alessandro, Willer, Margaret, Meetze, Kristan, Gostissa, Monica, Meehl, Michael A., Shaffer, Donald R.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Bivalent intra-spike binding provides durability against emergent Omicron lineages: Results from a global consortium
Callaway, Heather M., Hastie, Kathryn M., Schendel, Sharon L., Li, Haoyang, Yu, Xiaoying, Shek, Jeremy, Buck, Tierra, Hui, Sean, Bedinger, Dan, Troup, Camille, Dennison, S. Moses, Li, Kan, Alpert, Michael D., Bailey, Charles C., Benzeno, Sharon, Bonnevier, Jody L., Chen, Jin-Qiu, Chen, Charm, Cho, Hyeseon, Crompton, Peter D., Dussupt, Vincent, Entzminger, Kevin C., Ezzyat, Yassine, Fleming, Jonathan K., Geukens, Nick, Gilbert, Amy E., Guan, Yongjun, Han, Xiaojian, Harvey, Christopher J., Hatler, Julia M., Howie, Bryan, Hu, Chao, Huang, Ailong, Imbrechts, Maya, Jin, Aishun, Kamachi, Nik, Keitany, Gladys, Klinger, Mark, Kolls, Jay K., Krebs, Shelly J., Li, Tingting, Luo, Feiyan, Maruyama, Toshiaki, Meehl, Michael A., Mendez-Rivera, Letzibeth, Musa, Andrea, Okumura, C.J., Rubin, Benjamin E.R., Sato, Aaron K., Shen, Meiying, Singh, Anirudh, Song, Shuyi, Tan, Joshua, Trimarchi, Jeffrey M., Upadhyay, Dhruvkumar P., Wang, Yingming, Yu, Lei, Yuan, Tom Z., Yusko, Erik, Peters, Bjoern, Tomaras, Georgia, Saphire, Erica Ollmann
Published in Cell reports (Cambridge) (31.01.2023)
Published in Cell reports (Cambridge) (31.01.2023)
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