Discovery of PF-184563, a potent and selective V1a antagonist for the treatment of dysmenorrhoea. The influence of compound flexibility on microsomal stability
Johnson, Patrick S., Ryckmans, Thomas, Bryans, Justin, Beal, Dave M., Dack, Kevin N., Feeder, Neil, Harrison, Anthony, Lewis, Mark, Mason, Helen J., Mills, James, Newman, Julie, Pasquinet, Christelle, Rawson, Dave J., Roberts, Lee R., Russell, Rachel, Spark, Deborah, Stobie, Alan, Underwood, Toby J., Ward, Robin, Wheeler, Simon
Published in Bioorganic & medicinal chemistry letters (01.10.2011)
Published in Bioorganic & medicinal chemistry letters (01.10.2011)
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TEMPO-Mediated Electrooxidation of Primary and Secondary Alcohols in a Microfluidic Electrolytic Cell
Hill-Cousins, Joseph T., Kuleshova, Jekaterina, Green, Robert A., Birkin, Peter R., Pletcher, Derek, Underwood, Toby J., Leach, Stuart G., Brown, Richard C. D.
Published in ChemSusChem (13.02.2012)
Published in ChemSusChem (13.02.2012)
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A simple and inexpensive microfluidic electrolysis cell
Kuleshova, Jekaterina, Hill-Cousins, Joseph T., Birkin, Peter R., Brown, Richard C.D., Pletcher, Derek, Underwood, Toby J.
Published in Electrochimica acta (15.04.2011)
Published in Electrochimica acta (15.04.2011)
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4-Cyanophenols bearing metabolically robust substituents
Johnson, Patrick S., Underwood, Toby J., Wheeler, Simon
Published in Tetrahedron letters (22.06.2011)
Published in Tetrahedron letters (22.06.2011)
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Preparation of triazolobenzodiazepine derivatives as Vasopressin V1a antagonists
Beal, David M., Bryans, Justin S., Johnson, Patrick S., Newman, Julie, Pasquinet, Christelle, Peakman, Torren M., Ryckmans, Thomas, Underwood, Toby J., Wheeler, Simon
Published in Tetrahedron letters (09.11.2011)
Published in Tetrahedron letters (09.11.2011)
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Development of a Practical Synthesis of the Progesterone Receptor Antagonist 4-{[3-Cyclopropyl-1-(mesylmethyl)-5-methyl-1H-pyrazol-4-yl]oxy}-2,6-dimethylbenzonitrile
Bradley, Paul A, de Koning, Pieter D, Johnson, Patrick S, Lecouturier, Yann C, McManus, David J, Robin, Aurelie, Underwood, Toby J
Published in Organic process research & development (18.09.2009)
Published in Organic process research & development (18.09.2009)
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Preparation of triazolobenzodiazepine derivatives as Vasopressin Via antagonists
BEAL, David M, BRYANS, Justin S, JOHNSON, Patrick S, NEWMAN, Julie, PASQUINET, Christelle, PEAKMAN, Torren M, RYCKMANS, Thomas, UNDERWOOD, Toby J, WHEELER, Simon
Published in Tetrahedron letters (2011)
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Published in Tetrahedron letters (2011)
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Synthetic Studies on a Nonsteroidal Progesterone Metabolite: Regioselective N-Alkylation of an Activated Pyrazole
Bradley, Paul A., de Koning, Pieter D., Gibson, Karl R., Lecouturier, Yann C., MacKenny, Malcolm C., Morao, Inaki, Poinsard, Cedric, Underwood, Toby J.
Published in Synlett (01.04.2010)
Published in Synlett (01.04.2010)
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A Convenient Synthesis of Highly Substituted 3-N,N-Dialkylamino-1,2,4-triazoles
Batchelor, David V., Beal, David M., Brown, T. Bruce, Ellis, David, Gordon, David W., Johnson, Patrick S., Mason, Helen J., Ralph, Michael J., Underwood, Toby J., Wheeler, Simon
Published in Synlett (01.10.2008)
Published in Synlett (01.10.2008)
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Synthesis of 1,2-disubstituted-3-alkylidenylpyrrolidines via a one-pot three-component reaction
Huang, Wenwei, O’Donnell, Mary-Margaret, Bi, Grace, Liu, Jifeng, Yu, Libing, Baldino, Carmen M., Bell, Andrew S., Underwood, Toby J.
Published in Tetrahedron letters (08.11.2004)
Published in Tetrahedron letters (08.11.2004)
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ChemInform Abstract: A Convenient Synthesis of Highly Substituted 3-N,N-Dialkylamino-1,2,4-triazoles
Batchelor, David V., Beal, David M., Brown, T. Bruce, Ellis, David, Gordon, David W., Johnson, Patrick S., Mason, Helen J., Ralph, Michael J., Underwood, Toby J., Wheeler, Simon
Published in ChemInform (03.02.2009)
Published in ChemInform (03.02.2009)
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Synthesis of 1,2-Disubstituted-3-alkylidenylpyrrolidines via a One-Pot Three-Component Reaction
Huang, Wenwei, O'Donnell, Mary-Margaret, Bi, Grace, Liu, Jifeng, Yu, Libing, Baldino, Carmen M., Bell, Andrew S., Underwood, Toby J.
Published in ChemInform (22.02.2005)
Published in ChemInform (22.02.2005)
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