Targeting lysyl oxidase (LOX) overcomes chemotherapy resistance in triple negative breast cancer
Saatci, Ozge, Kaymak, Aysegul, Raza, Umar, Ersan, Pelin G., Akbulut, Ozge, Banister, Carolyn E., Sikirzhytski, Vitali, Tokat, Unal Metin, Aykut, Gamze, Ansari, Suhail A., Dogan, Hayriye Tatli, Dogan, Mehmet, Jandaghi, Pouria, Isik, Aynur, Gundogdu, Fatma, Kosemehmetoglu, Kemal, Dizdar, Omer, Aksoy, Sercan, Akyol, Aytekin, Uner, Aysegul, Buckhaults, Phillip J., Riazalhosseini, Yasser, Sahin, Ozgur
Published in Nature communications (15.05.2020)
Published in Nature communications (15.05.2020)
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Journal Article
Durable radiologic and molecular complete response following nivolumab in an HNSCC patient with UV signature and HIV
Adibi, Ashkan, Tokat, Ünal Metin, Özgü, Eylül, Mamyrov, Nurseit, Aydın, Esranur, Bilgiç, Şevval Nur, Tutar, Onur, Demiray, Mutlu
Published in Oral oncology (01.07.2024)
Published in Oral oncology (01.07.2024)
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Journal Article
Case report: Precision guided reactive cancer management: molecular complete response in heavily pretreated metastatic CRC by dual immunotherapy and sorafenib
Aydın, Esranur, Tokat, Ünal Metin, Adibi, Ashkan, Özgü, Eylül, Bilgiç, Şevval Nur, Demiray, Mutlu
Published in Frontiers in oncology (01.07.2024)
Published in Frontiers in oncology (01.07.2024)
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Journal Article
Targeting HIF1-alpha/miR-326/ITGA5 axis potentiates chemotherapy response in triple-negative breast cancer
Assidicky, Ridho, Tokat, Unal Metin, Tarman, Ibrahim Oguzhan, Saatci, Ozge, Ersan, Pelin Gulizar, Raza, Umar, Ogul, Hasan, Riazalhosseini, Yasser, Can, Tolga, Sahin, Ozgur
Published in Breast cancer research and treatment (01.06.2022)
Published in Breast cancer research and treatment (01.06.2022)
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Journal Article
PARP inhibitor combinations with high-dose vitamin C in the treatment of Ewing sarcoma: two case reports and mechanistic overview
Adibi, Ashkan, Tokat, Ünal Metin, Özgü, Eylül, Aydın, Esranur, Demiray, İrem, Demiray, Mutlu
Published in Therapeutic advances in medical oncology (01.01.2023)
Published in Therapeutic advances in medical oncology (01.01.2023)
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Journal Article
Navigating uncharted territory: a case report and literature review on the remarkable response to personalized crizotinib containing combinational therapy in a pazopanib refractory patient with novel alterations
Aydın, Esranur, Tokat, Ünal Metin, Özgü, Eylül, Adibi, Ashkan, Tutar, Onur, Kurzrock, Razelle, Demiray, Mutlu
Published in Therapeutic advances in medical oncology (01.01.2024)
Published in Therapeutic advances in medical oncology (01.01.2024)
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Journal Article
Toxic PARP trapping upon cAMP-induced DNA damage reinstates the efficacy of endocrine therapy and CDK4/6 inhibitors in treatment-refractory ER+ breast cancer
Saatci, Ozge, Cetin, Metin, Uner, Meral, Tokat, Unal Metin, Chatzistamou, Ioulia, Ersan, Pelin Gulizar, Montaudon, Elodie, Akyol, Aytekin, Aksoy, Sercan, Uner, Aysegul, Marangoni, Elisabetta, Sajish, Mathew, Sahin, Ozgur
Published in Nature communications (02.11.2023)
Published in Nature communications (02.11.2023)
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Journal Article
Targeting LINC00152 activates cAMP/Ca2+/ferroptosis axis and overcomes tamoxifen resistance in ER+ breast cancer
Saatci, Ozge, Alam, Rashedul, Huynh-Dam, Kim-Tuyen, Isik, Aynur, Uner, Meral, Belder, Nevin, Ersan, Pelin Gulizar, Tokat, Unal Metin, Ulukan, Burge, Cetin, Metin, Calisir, Kubra, Gedik, Mustafa Emre, Bal, Hilal, Sener Sahin, Ozlem, Riazalhosseini, Yasser, Thieffry, Denis, Gautheret, Daniel, Ogretmen, Besim, Aksoy, Sercan, Uner, Aysegul, Akyol, Aytekin, Sahin, Ozgur
Published in Cell death & disease (15.06.2024)
Published in Cell death & disease (15.06.2024)
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Journal Article
Evaluation of the Relationship between Aromatase/Sirtuin1 Interaction and miRNA Expression in Human Neuroblastoma Cells
Kartal, Yasemin, Tokat, Unal Metin, Kelicen-Ugur, Pelin, Yılmaz, Serkan, Karahan, Sevilay, Budak, Murat Timur
Published in Current molecular pharmacology (01.01.2023)
Published in Current molecular pharmacology (01.01.2023)
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Journal Article
Exceptional Response to MEK Inhibition in a Patient With RAF1-Mutant Myxofibrosarcoma: Case Report and Mechanistic Overview
Özgü, Eylül, Aydin, Esranur, Adibi, Ashkan, Tokat, Ünal Metin, Tutar, Onur, Hu, Jiancheng, Demiray, Irem, Kurzrock, Razelle, Demiray, Mutlu
Published in JCO precision oncology (01.09.2023)
Published in JCO precision oncology (01.09.2023)
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Journal Article
Personalized Immunotherapy Achieves Complete Response in Metastatic Adenoid Cystic Carcinoma Despite Lack of Conventional Biomarkers
Tokat, Ünal Metin, Adibi, Ashkan, Aydın, Esranur, Özgü, Eylül, Bilgiç, Şevval Nur, Tutar, Onur, Özbek Doğançay, Merve, Demiray, İrem, Demiray, Mutlu
Published in Current oncology (Toronto) (29.09.2024)
Published in Current oncology (Toronto) (29.09.2024)
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Journal Article
Targeting LINC00152 activates cAMP/Ca2+/ferroptosis axis and overcomes tamoxifen resistance in ER+ breast cancer
Saatci, Ozge, Alam, Rashed, Huynh-Dam, Kim-Tuyen, Isik, Aynur, Uner, Meral, Belder, Nevin, Ersan, Pelin Gulizar, Cetin, Metin, Unal Metin Tokat, Gedik, Mustafa Emre, Bal, Hilal, Ozlem Sener Sahin, Riazalhosseini, Yasser, Thieffry, Denis, Gautheret, Daniel, Ogretmen, Besim, Aksoy, Sercan, Uner, Aysegul, Akyol, Aytekin, Sahin, Ozgur
Published in bioRxiv (05.11.2023)
Published in bioRxiv (05.11.2023)
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Paper
Therapeutic vulnerabilities and pan-cancer landscape of BRAF class III mutations in epithelial solid tumors
Özgü, Eylül, Kaplan, Benjamin G., Sivakumar, Smruthy, Sokol, Ethan S., Aydın, Esranur, Tokat, Ünal Metin, Adibi, Ashkan, Karakoç, Ebru Gül, Hu, Jiancheng, Kurzrock, Razelle, Demiray, Mutlu
Published in BJC Reports (08.10.2024)
Published in BJC Reports (08.10.2024)
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Journal Article
Comparison of Two Scleral Incision Techniques in 23-Gauge Transconjunctival Vitrectomy
Unal, Metin, Balikoglu, Melike, Teke, Mehmet Yasin, Koklu, Gultekin
Published in Ophthalmic surgery, lasers & imaging (01.11.2013)
Published in Ophthalmic surgery, lasers & imaging (01.11.2013)
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Journal Article
Abstract 2121: Overcoming tamoxifen resistance and inhibiting metastatic recurrence in estrogen receptor-positive breast cancer
Ersan, Pelin Gulizar, Saatci, Ozge, Tarman, Oguzhan, Mishra, Rasmi, Belder, Nevin, Tokat, Unal Metin, Riazalhosseini, Yasser, Sahin, Ozgur
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article