Novel effects of glycyrrhetinic acid on the central nervous system tumorigenic progenitor cells: Induction of actin disruption and tumor cell-selective toxicity
Yamaguchi, Hideaki, Noshita, Toshiro, Yu, Tao, Kidachi, Yumi, Kamiie, Katsuyoshi, Umetsu, Hironori, Ryoyama, Kazuo
Published in European journal of medicinal chemistry (01.07.2010)
Published in European journal of medicinal chemistry (01.07.2010)
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Glycyrrhetinic Acid Induces Anoikis-Like Death and Cytoskeletal Disruption in the Central Nervous System Tumorigenic Cells
Yamaguchi, Hideaki, Kidachi, Yumi, Kamiie, Katsuyoshi, Noshita, Toshiro, Umetsu, Hironori, Ryoyama, Kazuo
Published in Biological & Pharmaceutical Bulletin (2010)
Published in Biological & Pharmaceutical Bulletin (2010)
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Isolation of Ursolic Acid from Apple Peels and Its Specific Efficacy as a Potent Antitumor Agent
Yamaguchi, Hideaki, Noshita, Toshiro, Kidachi, Yumi, Umetsu, Hironori, Hayashi, Masahiko, Komiyama, Kanki, Funayama, Shinji, Ryoyama, Kazuo
Published in Journal of Health Science (2008)
Published in Journal of Health Science (2008)
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Differentiation of Serum-Free Mouse Embryo Cells into an Astrocytic Lineage is Associated with the Asymmetric Production of Early Neural, Neuronal and Glial Markers
Yamaguchi, Hideaki, Kidachi, Yumi, Umetsu, Hironori, Ryoyama, Kazuo
Published in Biological & pharmaceutical bulletin (01.05.2008)
Published in Biological & pharmaceutical bulletin (01.05.2008)
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Low-level bisphenol A increases production of glial fibrillary acidic protein in differentiating astrocyte progenitor cells through excessive STAT3 and Smad1 activation
Yamaguchi, Hideaki, Zhu, Jun, Yu, Tao, Sasaki, Kazuo, Umetsu, Hironori, Kidachi, Yumi, Ryoyama, Kazuo
Published in Toxicology (Amsterdam) (21.09.2006)
Published in Toxicology (Amsterdam) (21.09.2006)
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Detection of 6-(Methylsulfinyl)hexyl Isothiocyanate (6-MITC) and Its Conjugate with N-Acetyl-L-cysteine (NAC) by High Performance Liquid Chromatograpy-Atmospheric Pressure Chemical Ionization Mass Spectrometry (HPLC-MS/APCI)
Yamaguchi, Hideaki, Noshita, Toshiro, Kidachi, Yumi, Umetsu, Hironori, Fuke, Yoko, Ryoyama, Kazuo
Published in Chemical & pharmaceutical bulletin (01.05.2008)
Published in Chemical & pharmaceutical bulletin (01.05.2008)
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Mouse 11β-Hydroxysteroid Dehydrogenase Type 2 for Human Application: Homology Modeling, Structural Analysis and Ligand-Receptor Interaction
Yamaguchi, Hideaki, Akitaya, Tatsuo, Kidachi, Yumi, Kamiie, Katsuyoshi, Noshita, Toshiro, Umetsu, Hironori, Ryoyama, Kazuo
Published in Cancer informatics (01.01.2011)
Published in Cancer informatics (01.01.2011)
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The augmenting activity of 6-(Methylsulfinyl)hexyl isothiocyanate on cellular glutathione levels is less sensitive to thiol compounds than its cytotoxic activity
Kidachi, Y.(Aomori Univ. (Japan)), Noshita, T, Yamaguchi, H, Umetsu, H, Fuke, Y, Ryoyama, K
Published in Bioscience, biotechnology, and biochemistry (01.06.2009)
Published in Bioscience, biotechnology, and biochemistry (01.06.2009)
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Purification and properties of an aminopeptidase from the mid-gut gland of scallop ( Patinopecten yessoensis)
Umetsu, Hironori, Arai, Mito, Ota, Toshinori, Kudo, Ryohei, Sugiura, Hitomi, Ishiyama, Hiroyuki, Sasaki, Kazuo
Published in Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology (01.12.2003)
Published in Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology (01.12.2003)
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Differentiation of Serum-Free Mouse Embryo Cells into an Astrocytic Lineage is Associated with the Asymmetric Production of Early Neural, Neuronal and Glial Markers
Hideaki YAMAGUCHIa, Yumi KIDACHIa, Hironori UMETSUb, Kazuo RYOYAMAa
Published in Biological & Pharmaceutical Bulletin (2008)
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Published in Biological & Pharmaceutical Bulletin (2008)
Journal Article
Detection of 6-(Methylsulfinyl)hexyl Isothiocyanate(6-MITC) and Its Conjugate with N-Acetyl-L-cysteine(NAC) by High Performance Liquid Chromatograpy-Atmospheric Pressure Chemical Ionization Mass Spectrometry(HPLC-MS/APCI)
Hideaki YAMAGUCHIa, Toshiro NOSHITAa, Yumi KIDACHIa, Hironori UMETSUb, Yoko FUKEc, Kazuo RYOYAMAa
Published in Chemical & Pharmaceutical Bulletin (2008)
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Published in Chemical & Pharmaceutical Bulletin (2008)
Journal Article
Utilization of 6-(methylsulfinyl)hexyl isothiocyanate for sensitization of tumor cells to antitumor agents in combination therapies
Yamaguchi, Hideaki, Kidachi, Yumi, Kamiie, Katsuyoshi, Noshita, Toshiro, Umetsu, Hironori, Fuke, Yoko, Ryoyama, Kazuo
Published in Biochemical pharmacology (15.08.2013)
Published in Biochemical pharmacology (15.08.2013)
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Intracellular accumulation of structurally varied isothiocyanates correlates with inhibition of nitric oxide production in proinflammatory stimuli-activated tumorigenic macrophage-like cells
Yamaguchi, Hideaki, Kamiie, Katsuyoshi, Kidachi, Yumi, Noshita, Toshiro, Umetsu, Hironori, Fuke, Yoko, Ryoyama, Kazuo
Published in Bioorganic & medicinal chemistry (01.01.2014)
Published in Bioorganic & medicinal chemistry (01.01.2014)
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Selective cytotoxicity of glycyrrhetinic acid against tumorigenic r/m HM-SFME-1 cells: Potential involvement of H-Ras downregulation
Yu, Tao, Yamaguchi, Hideaki, Noshita, Toshiro, Kidachi, Yumi, Umetsu, Hironori, Ryoyama, Kazuo
Published in Toxicology letters (15.02.2010)
Published in Toxicology letters (15.02.2010)
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Frequency of Mutations of the Transgene, which might Result in the Loss of the Glyphosate-Tolerant Phenotype, was Lowered in Roundup Ready® Soybeans
Ogasawara, Takeshi, Chikagawa, Yukie, Arakawa, Fumihiro, Nozaki, Asami, Itoh, Yoshio, Sasaki, Kazuo, Umetsu, Hironori, Watanabe, Takahiro, Akiyama, Hiroshi, Maitani, Tamio, Toyoda, Masatake, Kamada, Hiroshi, Goda, Yukihiro, Ozeki, Yoshihiro
Published in Journal of Health Science (2005)
Published in Journal of Health Science (2005)
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Action of carboxypeptidase W on oligopeptides containing carboxy-terminally amidated peptides
Umetsu, Hironori, Hishinuma, Kiyoshi, Wake, Hitoshi, Takeuchi, Michio, Ichishima, Eiji
Published in Phytochemistry (Oxford) (01.07.1997)
Published in Phytochemistry (Oxford) (01.07.1997)
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Ligand-receptor Interaction between Triterpenoids and the 11β-Hydroxysteroid dehydrogenase type 2 (11βHSD2) Enzyme Predicts Their Toxic Effects against Tumorigenic r/m HM-SFME-1 Cells
Yamaguchi, Hideaki, Yu, Tao, Noshita, Toshiro, Kidachi, Yumi, Kamiie, Katsuyoshi, Yoshida, Kenji, Akitaya, Tatsuo, Umetsu, Hironori, Ryoyama, Kazuo
Published in The Journal of biological chemistry (21.10.2011)
Published in The Journal of biological chemistry (21.10.2011)
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Isolation of 2-Methylisocitrate Dehydratase, a New Enzyme Serving in the Methylcitric Acid Cycle for Propionate Metabolism, from Yallowia lipolytica
Aoki, Hiroyuki, Uchiyama, Hiroo, Umetsu, Hironori, Tabuchi, Takeshi
Published in Bioscience, biotechnology, and biochemistry (1995)
Published in Bioscience, biotechnology, and biochemistry (1995)
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Journal Article
Homology modeling and structural analysis of 11β-hydroxysteroid dehydrogenase type 2
Yamaguchi, Hideaki, Akitaya, Tatsuo, Yu, Tao, Kidachi, Yumi, Kamiie, Katsuyoshi, Noshita, Toshiro, Umetsu, Hironori, Ryoyama, Kazuo
Published in European journal of medicinal chemistry (01.04.2011)
Published in European journal of medicinal chemistry (01.04.2011)
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