Frontline Science: Concanavalin A‐induced acute hepatitis is attenuated in vitamin D receptor knockout mice with decreased immune cell function
Umeda, Naoki, Endo‐Umeda, Kaori, Nakashima, Hiroyuki, Kato, Shigeaki, Seki, Shuhji, Makishima, Makoto
Published in Journal of leukocyte biology (01.10.2019)
Published in Journal of leukocyte biology (01.10.2019)
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Journal Article
Liver X Receptors Regulate Cholesterol Metabolism and Immunity in Hepatic Nonparenchymal Cells
Endo-Umeda, Kaori, Makishima, Makoto
Published in International journal of molecular sciences (11.10.2019)
Published in International journal of molecular sciences (11.10.2019)
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Journal Article
Liver X receptors regulate natural killer T cell population and antitumor activity in the liver of mice
Endo-Umeda, Kaori, Nakashima, Hiroyuki, Uno, Shigeyuki, Toyoshima, Shota, Umeda, Naoki, Komine-Aizawa, Shihoko, Seki, Shuhji, Makishima, Makoto
Published in Scientific reports (19.11.2021)
Published in Scientific reports (19.11.2021)
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Journal Article
Development of Tetrachlorophthalimides as Liver X Receptor β (LXRβ)-Selective Agonists
Nomura, Sayaka, Endo-Umeda, Kaori, Makishima, Makoto, Hashimoto, Yuichi, Ishikawa, Minoru
Published in ChemMedChem (19.10.2016)
Published in ChemMedChem (19.10.2016)
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Journal Article
Property changes in materials due to atomic oxygen in the low Earth orbit
Goto, Aki, Umeda, Kaori, Yukumatsu, Kazuki, Kimoto, Yugo
Published in CEAS space journal (01.07.2021)
Published in CEAS space journal (01.07.2021)
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Journal Article
Contrasting functional responses of resident Kupffer cells and recruited liver macrophages to irradiation and liver X receptor stimulation
Ishikiriyama, Takuya, Nakashima, Hiroyuki, Endo-Umeda, Kaori, Nakashima, Masahiro, Ito, Seigo, Kinoshita, Manabu, Ikarashi, Masami, Makishima, Makoto, Seki, Shuhji
Published in PloS one (23.07.2021)
Published in PloS one (23.07.2021)
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Journal Article
Erythroid lineage Jak2V617F expression promotes atherosclerosis through erythrophagocytosis and macrophage ferroptosis
Liu, Wenli, Östberg, Nataliya K, Yalcinkaya, Mustafa, Dou, Huijuan, Endo-Umeda, Kaori, Tang, Yang, Hou, Xintong, Xiao, Tong, Filder, Trevor, Abramowicz, Sandra, Yang, Yong-Guang, Soehnlein, Oliver, Tall, Alan R, Wang, Nan
Published in The Journal of clinical investigation (01.07.2022)
Published in The Journal of clinical investigation (01.07.2022)
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Journal Article
Synthesis and In Vitro Evaluation of Novel Liver X Receptor Agonists Based on Naphthoquinone Derivatives
Nishioka, Tatsuma, Endo-Umeda, Kaori, Ito, Yuki, Shimoda, Akane, Takeuchi, Atsuko, Tode, Chisato, Hirota, Yoshihisa, Osakabe, Naomi, Makishima, Makoto, Suhara, Yoshitomo
Published in Molecules (Basel, Switzerland) (26.11.2019)
Published in Molecules (Basel, Switzerland) (26.11.2019)
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Journal Article
Increased SLAMF7high monocytes in myelofibrosis patients harboring JAK2V617F provide a therapeutic target of elotuzumab
Maekawa, Takaaki, Kato, Shoichiro, Kawamura, Toshikuni, Takada, Kohei, Sone, Takehiro, Ogata, Hiraku, Saito, Keita, Izumi, Takuya, Nagao, Shigeki, Takano, Kosuke, Okada, Yosuke, Tachi, Noriaki, Teramoto, Masahiro, Horiuchi, Toshikatsu, Hikota-Saga, Reina, Endo-Umeda, Kaori, Uno, Shigeyuki, Osawa, Yukiko, Kobayashi, Ayako, Kobayashi, Shinichi, Sato, Ken, Hashimoto, Michihiro, Suzu, Shinya, Usuki, Kensuke, Morishita, Soji, Araki, Marito, Makishima, Makoto, Komatsu, Norio, Kimura, Fumihiko
Published in Blood (05.09.2019)
Published in Blood (05.09.2019)
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Journal Article
Activation of LXRs using the synthetic agonist GW3965 represses the production of pro-inflammatory cytokines by murine mast cells
Nunomura, Satoshi, Okayama, Yoshimichi, Matsumoto, Kenji, Hashimoto, Noriko, Endo-Umeda, Kaori, Terui, Tadashi, Makishima, Makoto, Ra, Chisei
Published in Allergology international (01.09.2015)
Published in Allergology international (01.09.2015)
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Journal Article
Cholesterol accumulation in macrophages drives NETosis in atherosclerotic plaques via IL-1β secretion
Yalcinkaya, Mustafa, Fotakis, Panagiotis, Liu, Wenli, Endo-Umeda, Kaori, Dou, Huijuan, Abramowicz, Sandra, Xiao, Tong, Libby, Peter, Wang, Nan, Tall, Alan R, Westerterp, Marit
Published in Cardiovascular research (02.05.2023)
Published in Cardiovascular research (02.05.2023)
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Journal Article
Oxidized Phospholipids Promote NETosis and Arterial Thrombosis in LNK(SH2B3) Deficiency
Dou, Huijuan, Kotini, Andriana, Liu, Wenli, Fidler, Trevor, Endo-Umeda, Kaori, Sun, Xiaoli, Olszewska, Malgorzata, Xiao, Tong, Abramowicz, Sandra, Yalcinkaya, Mustafa, Hardaway, Brian, Tsimikas, Sotirios, Que, Xuchu, Bick, Alexander, Emdin, Conor, Natarajan, Pradeep, Papapetrou, Eirini P, Witztum, Joseph L, Wang, Nan, Tall, Alan R
Published in Circulation (New York, N.Y.) (14.12.2021)
Published in Circulation (New York, N.Y.) (14.12.2021)
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Journal Article
Structural development of tetrachlorophthalimides as liver X receptor β (LXRβ)-selective agonists with improved aqueous solubility
Nomura, Sayaka, Endo-Umeda, Kaori, Fujii, Shinya, Makishima, Makoto, Hashimoto, Yuichi, Ishikawa, Minoru
Published in Bioorganic & medicinal chemistry letters (15.02.2018)
Published in Bioorganic & medicinal chemistry letters (15.02.2018)
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Journal Article
Myeloid LXR (Liver X Receptor) Deficiency Induces Inflammatory Gene Expression in Foamy Macrophages and Accelerates Atherosclerosis
Endo-Umeda, Kaori, Kim, Eunyoung, Thomas, David G, Liu, Wenli, Dou, Huijuan, Yalcinkaya, Mustafa, Abramowicz, Sandra, Xiao, Tong, Antonson, Per, Gustafsson, Jan-Åke, Makishima, Makoto, Reilly, Muredach P, Wang, Nan, Tall, Alan R
Published in Arteriosclerosis, thrombosis, and vascular biology (01.06.2022)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.06.2022)
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Journal Article
Erythroid lineage [Jak2.sup.V617F] expression promotes atherosclerosis through erythrophagocytosis and macrophage ferroptosis
Liu, Wenli, Ostberg, Nataliya, Yalcinkaya, Mustafa, Dou, Huijuan, Endo-Umeda, Kaori, Tang, Yang, Hou, Xintong, Xiao, Tong, Fidler, Trevor P, Abramowicz, Sandra, Yang, Yong-Guang, Soehnlein, Oliver, Tall, Alan R, Wang, Nan
Published in The Journal of clinical investigation (01.07.2022)
Published in The Journal of clinical investigation (01.07.2022)
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Journal Article