Site-Specific Conjugation of Native Antibodies Using Engineered Microbial Transglutaminases
Dickgiesser, Stephan, Rieker, Marcel, Mueller-Pompalla, Dirk, Schröter, Christian, Tonillo, Jason, Warszawski, Shira, Raab-Westphal, Sabine, Kühn, Stefanie, Knehans, Tim, Könning, Doreen, Dotterweich, Julia, Betz, Ulrich A. K, Anderl, Jan, Hecht, Stefan, Rasche, Nicolas
Published in Bioconjugate chemistry (15.04.2020)
Published in Bioconjugate chemistry (15.04.2020)
Get full text
Journal Article
Regional Neural Activation Defines a Gateway for Autoreactive T Cells to Cross the Blood-Brain Barrier
Arima, Yasunobu, Harada, Masaya, Kamimura, Daisuke, Park, Jin-Haeng, Kawano, Fuminori, Yull, Fiona E., Kawamoto, Tadafumi, Iwakura, Yoichiro, Betz, Ulrich A.K., Márquez, Gabriel, Blackwell, Timothy S., Ohira, Yoshinobu, Hirano, Toshio, Murakami, Masaaki
Published in Cell (03.02.2012)
Published in Cell (03.02.2012)
Get full text
Journal Article
High Levels of Cre Expression in Neuronal Progenitors Cause Defects in Brain Development Leading to Microencephaly and Hydrocephaly
Forni, Paolo E, Scuoppo, Claudio, Imayoshi, Itaru, Taulli, Riccardo, Dastru, Walter, Sala, Valentina, Betz, Ulrich A. K, Muzzi, Patrizia, Martinuzzi, Daniela, Vercelli, Alessandro E, Kageyama, Ryoichiro, Ponzetto, Carola
Published in The Journal of neuroscience (13.09.2006)
Published in The Journal of neuroscience (13.09.2006)
Get full text
Journal Article
IL-6-gp130-STAT3 in T cells directs the development of IL-17+ T[sub]h with a minimum effect on that of Treg in the steady state
Nishihara, Mika, Ogura, Hideki, Ueda, Naoko, Tsuruoka, Mineko, Kitabayashi, Chika, Tsuji, Fumio, Aono, Hiroyuki, Ishihara, Katsuhiko, Huseby, Eric, Betz, Ulrich A K, Murakami, Masaaki, Hirano, Toshio
Published in International immunology (01.06.2007)
Published in International immunology (01.06.2007)
Get full text
Journal Article
PROLinkSingle Step Circularization and Purification Procedure for the Generation of an Improved Variant of Human Growth Hormone
Rasche, Nicolas, Tonillo, Jason, Rieker, Marcel, Becker, Stefan, Dorr, Brent, Ter-Ovanesyan, Dmitry, Betz, Ulrich A. K, Hock, Björn, Kolmar, Harald
Published in Bioconjugate chemistry (18.05.2016)
Published in Bioconjugate chemistry (18.05.2016)
Get full text
Journal Article
Locked by Design: A Conformationally Constrained Transglutaminase Tag Enables Efficient Site-Specific Conjugation
Siegmund, Vanessa, Schmelz, Stefan, Dickgiesser, Stephan, Beck, Jan, Ebenig, Aileen, Fittler, Heiko, Frauendorf, Holm, Piater, Birgit, Betz, Ulrich A. K., Avrutina, Olga, Scrima, Andrea, Fuchsbauer, Hans-Lothar, Kolmar, Harald
Published in Angewandte Chemie International Edition (02.11.2015)
Published in Angewandte Chemie International Edition (02.11.2015)
Get full text
Journal Article
Target 2035 - an update on private sector contributions
Ackloo, Suzanne, Antolin, Albert A, Bartolome, Jose Manuel, Beck, Hartmut, Bullock, Alex, Betz, Ulrich A. K, Böttcher, Jark, Brown, Peter J, Chaturvedi, Menorca, Crisp, Alisa, Daniels, Danette, Dreher, Jan, Edfeldt, Kristina, Edwards, Aled M, Egner, Ursula, Elkins, Jon, Fischer, Christian, Glendorf, Tine, Goldberg, Steven, Hartung, Ingo V, Hillisch, Alexander, Homan, Evert, Knapp, Stefan, Köster, Markus, Krämer, Oliver, Llaveria, Josep, Lessel, Uta, Lindemann, Sven, Linderoth, Lars, Matsui, Hisanori, Michel, Maurice, Montel, Florian, Mueller-Fahrnow, Anke, Müller, Susanne, Owen, Dafydd R, Saikatendu, Kumar Singh, Santhakumar, Vijayaratnam, Sanderson, Wendy, Scholten, Cora, Schapira, Matthieu, Sharma, Sujata, Shireman, Brock, Sundström, Michael, Todd, Matthew H, Tredup, Claudia, Venable, Jennifer, Willson, Timothy M, Arrowsmith, Cheryl H
Published in MedChemComm (22.06.2023)
Published in MedChemComm (22.06.2023)
Get full text
Journal Article
Synthetic Biology Category Wins the 350th Anniversary Merck Innovation Cup
Matos, Ângelo P., Kauffman, Amy, Vickery, Christopher, Naegeli, Kaleb, Strittmatter, Lisa, Sybirna, Anastasiya, van Blijswijk, Janneke, Adlung, Lorenz, Berbasova, Tetyana, Enterina, Jhon, Eismann, Lena, Tierney, Braden, Jordi, Josua, Zhu, Lian, Verkuijl, Sebald, Tallorin, Lorillee, Wehling, Arne, Ogden, Michael, Lammel, Stephan, Hasslacher, Maike K., Wuelfroth, Petra, Neumann, Siegfried, Tidona, Christian, Betz, Ulrich A.K.
Published in Trends in biotechnology (Regular ed.) (01.01.2020)
Published in Trends in biotechnology (Regular ed.) (01.01.2020)
Get full text
Journal Article
IFN-γ expression in CD8+ T cells regulated by IL-6 signal is involved in superantigen-mediated CD4+ T cell death
Atsumi, Toru, Sato, Masae, Kamimura, Daisuke, Moroi, Arisa, Iwakura, Yoichiro, Betz, Ulrich A. K., Yoshimura, Akihiko, Nishihara, Mika, Hirano, Toshio, Murakami, Masaaki
Published in International immunology (01.01.2009)
Published in International immunology (01.01.2009)
Get full text
Journal Article
Antiviral drug screen identifies DNA-damage response inhibitor as potent blocker of SARS-CoV-2 replication
Garcia, Gustavo, Sharma, Arun, Ramaiah, Arunachalam, Sen, Chandani, Purkayastha, Arunima, Kohn, Donald B., Parcells, Mark S., Beck, Sebastian, Kim, Heeyoung, Bakowski, Malina A., Kirkpatrick, Melanie G., Riva, Laura, Wolff, Karen C., Han, Brandon, Yuen, Constance, Ulmert, David, Purbey, Prabhat K., Scumpia, Philip, Beutler, Nathan, Rogers, Thomas F., Chatterjee, Arnab K., Gabriel, Gülsah, Bartenschlager, Ralf, Gomperts, Brigitte, Svendsen, Clive N., Betz, Ulrich A.K., Damoiseaux, Robert D., Arumugaswami, Vaithilingaraja
Published in Cell reports (Cambridge) (06.04.2021)
Published in Cell reports (Cambridge) (06.04.2021)
Get full text
Journal Article
Mice Reconstituted with DNA Polymerase β -Deficient Fetal Liver Cells Are Able to Mount a T Cell-Dependent Immune Response and Mutate Their Ig Genes Normally
Esposito, Gloria, Texido, Gemma, Ulrich A. K. Betz, Gu, Hua, Muller, Werner, Klein, Ulf, Rajewsky, Klaus
Published in Proceedings of the National Academy of Sciences - PNAS (01.02.2000)
Published in Proceedings of the National Academy of Sciences - PNAS (01.02.2000)
Get full text
Journal Article
Spontaneous Isopeptide Bond Formation as a Powerful Tool for Engineering Site-Specific Antibody-Drug Conjugates
Siegmund, Vanessa, Piater, Birgit, Zakeri, Bijan, Eichhorn, Thomas, Fischer, Frank, Deutsch, Carl, Becker, Stefan, Toleikis, Lars, Hock, Björn, Betz, Ulrich A. K., Kolmar, Harald
Published in Scientific reports (16.12.2016)
Published in Scientific reports (16.12.2016)
Get full text
Journal Article
Target 2035 - update on the quest for a probe for every protein
Müller, Susanne, Ackloo, Suzanne, Al Chawaf, Arij, Al-Lazikani, Bissan, Antolin, Albert, Baell, Jonathan B, Beck, Hartmut, Beedie, Shaunna, Betz, Ulrich A K, Bezerra, Gustavo Arruda, Brennan, Paul E, Brown, David, Brown, Peter J, Bullock, Alex N, Carter, Adrian J, Chaikuad, Apirat, Chaineau, Mathilde, Ciulli, Alessio, Collins, Ian, Dreher, Jan, Drewry, David, Edfeldt, Kristina, Edwards, Aled M, Egner, Ursula, Frye, Stephen V, Fuchs, Stephen M, Hall, Matthew D, Hartung, Ingo V, Hillisch, Alexander, Hitchcock, Stephen H, Homan, Evert, Kannan, Natarajan, Kiefer, James R, Knapp, Stefan, Kostic, Milka, Kubicek, Stefan, Leach, Andrew R, Lindemann, Sven, Marsden, Brian D, Matsui, Hisanori, Meier, Jordan L, Merk, Daniel, Michel, Maurice, Morgan, Maxwell R, Mueller-Fahrnow, Anke, Owen, Dafydd R, Perry, Benjamin G, Rosenberg, Saul H, Saikatendu, Kumar Singh, Schapira, Matthieu, Scholten, Cora, Sharma, Sujata, Simeonov, Anton, Sundström, Michael, Superti-Furga, Giulio, Todd, Matthew H, Tredup, Claudia, Vedadi, Masoud, von Delft, Frank, Willson, Timothy M, Winter, Georg E, Workman, Paul, Arrowsmith, Cheryl H
Published in MedChemComm (27.01.2022)
Published in MedChemComm (27.01.2022)
Get full text
Journal Article