HMGB2 Loss upon Senescence Entry Disrupts Genomic Organization and Induces CTCF Clustering across Cell Types
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Published in Molecular cell (17.05.2018)
Published in Molecular cell (17.05.2018)
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Combined VEGF and PD-L1 Blockade Displays Synergistic Treatment Effects in an Autochthonous Mouse Model of Small Cell Lung Cancer
Meder, Lydia, Schuldt, Philipp, Thelen, Martin, Schmitt, Anna, Dietlein, Felix, Klein, Sebastian, Borchmann, Sven, Wennhold, Kerstin, Vlasic, Ignacija, Oberbeck, Sebastian, Riedel, Richard, Florin, Alexandra, Golfmann, Kristina, Schlößer, Hans A, Odenthal, Margarete, Buettner, Reinhard, Wolf, Juergen, Hallek, Michael, Herling, Marco, von Bergwelt-Baildon, Michael, Reinhardt, H Christian, Ullrich, Roland T
Published in Cancer research (Chicago, Ill.) (01.08.2018)
Published in Cancer research (Chicago, Ill.) (01.08.2018)
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Tumor VEGF:VEGFR2 autocrine feed-forward loop triggers angiogenesis in lung cancer
Chatterjee, Sampurna, Heukamp, Lukas C, Siobal, Maike, Schöttle, Jakob, Wieczorek, Caroline, Peifer, Martin, Frasca, Davide, Koker, Mirjam, König, Katharina, Meder, Lydia, Rauh, Daniel, Buettner, Reinhard, Wolf, Jürgen, Brekken, Rolf A, Neumaier, Bernd, Christofori, Gerhard, Thomas, Roman K, Ullrich, Roland T
Published in The Journal of clinical investigation (01.04.2013)
Published in The Journal of clinical investigation (01.04.2013)
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A framework for identification of actionable cancer genome dependencies in small cell lung cancer
Sos, Martin L., Dietlein, Felix, Peifer, Martin, Schöttle, Jakob, Balke-Want, Hyatt, Müller, Christian, Koker, Mirjam, Richters, André, Heynck, Stefanie, Malchers, Florian, Heuckmann, Johannes M., Seidel, Danila, Eyers, Patrick A., Ullrich, Rolad T., Antonchick, Andrey P., Vintonyak, Viktor V., Schneider, Peter M., Ninomiya, Takashi, Waldmann, Herbert, Büttner, Reinhard, Rauh, Daniel, Heukamp, Lukas C., Thomas, Roman K.
Published in Proceedings of the National Academy of Sciences - PNAS (16.10.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (16.10.2012)
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Synergistic anti-angiogenic treatment effects by dual FGFR1 and VEGFR1 inhibition in FGFR1-amplified breast cancer
Golfmann, Kristina, Meder, Lydia, Koker, Mirjam, Volz, Caroline, Borchmann, Sven, Tharun, Lars, Dietlein, Felix, Malchers, Florian, Florin, Alexandra, Büttner, Reinhard, Rosen, Neal, Rodrik-Outmezguine, Vanessa, Hallek, Michael, Ullrich, Roland T.
Published in Oncogene (01.10.2018)
Published in Oncogene (01.10.2018)
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Frequent and focal FGFR1 amplification associates with therapeutically tractable FGFR1 dependency in squamous cell lung cancer
Weiss, Jonathan, Sos, Martin L, Seidel, Danila, Peifer, Martin, Zander, Thomas, Heuckmann, Johannes M, Ullrich, Roland T, Menon, Roopika, Maier, Sebastian, Soltermann, Alex, Moch, Holger, Wagener, Patrick, Fischer, Florian, Heynck, Stefanie, Koker, Mirjam, Schöttle, Jakob, Leenders, Frauke, Gabler, Franziska, Dabow, Ines, Querings, Silvia, Heukamp, Lukas C, Balke-Want, Hyatt, Ansén, Sascha, Rauh, Daniel, Baessmann, Ingelore, Altmüller, Janine, Wainer, Zoe, Conron, Matthew, Wright, Gavin, Russell, Prudence, Solomon, Ben, Brambilla, Elisabeth, Brambilla, Christian, Lorimier, Philippe, Sollberg, Steinar, Brustugun, Odd Terje, Engel-Riedel, Walburga, Ludwig, Corinna, Petersen, Iver, Sänger, Jörg, Clement, Joachim, Groen, Harry, Timens, Wim, Sietsma, Hannie, Thunnissen, Erik, Smit, Egbert, Heideman, Daniëlle, Cappuzzo, Federico, Ligorio, Claudia, Damiani, Stefania, Hallek, Michael, Beroukhim, Rameen, Pao, William, Klebl, Bert, Baumann, Matthias, Buettner, Reinhard, Ernestus, Karen, Stoelben, Erich, Wolf, Jürgen, Nürnberg, Peter, Perner, Sven, Thomas, Roman K
Published in Science translational medicine (15.12.2010)
Published in Science translational medicine (15.12.2010)
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Hepatic FTO is dispensable for the regulation of metabolism but counteracts HCC development in vivo
Mittenbühler, Melanie J., Saedler, Katarzyna, Nolte, Hendrik, Kern, Lara, Zhou, Jun, Qian, Shu-Bing, Meder, Lydia, Ullrich, Roland T., Brüning, Jens C., Wunderlich, F. Thomas
Published in Molecular metabolism (Germany) (01.12.2020)
Published in Molecular metabolism (Germany) (01.12.2020)
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EGFR Inhibition Strongly Modulates the Tumour Immune Microenvironment in EGFR-Driven Non-Small-Cell Lung Cancer
Selenz, Carolin, Compes, Anik, Nill, Marieke, Borchmann, Sven, Odenthal, Margarete, Florin, Alexandra, Brägelmann, Johannes, Büttner, Reinhard, Meder, Lydia, Ullrich, Roland T
Published in Cancers (16.08.2022)
Published in Cancers (16.08.2022)
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Circulating Tumor DNA Sequencing for Biologic Classification and Individualized Risk Stratification in Patients With Hodgkin Lymphoma
Heger, Jan-Michel, Mammadova, Laman, Mattlener, Julia, Sobesky, Sophia, Cirillo, Melita, Altmüller, Janine, Kirst, Elisabeth, Reinke, Sarah, Klapper, Wolfram, Bröckelmann, Paul J, Ferdinandus, Justin, Kaul, Helen, Schneider, Gundolf, Schneider, Jessica, Schleifenbaum, Julia Katharina, Ullrich, Roland T, Freihammer, Max, Awerkiew, Sabine, Lohmann, Mia, Klein, Florian, Nürnberg, Peter, Hallek, Michael, Rossi, Davide, Mauz-Körholz, Christine, Gattenlöhner, Stefan, Bräuninger, Andreas, Borchmann, Peter, von Tresckow, Bastian, Borchmann, Sven
Published in Journal of clinical oncology (30.09.2024)
Published in Journal of clinical oncology (30.09.2024)
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Early Prediction of Nonprogression in Advanced Non–Small-Cell Lung Cancer Treated With Erlotinib By Using [18F]Fluorodeoxyglucose and [18F]Fluorothymidine Positron Emission Tomography
Zander, Thomas, Scheffler, Matthias, Nogova, Lucia, Kobe, Carsten, Engel-Riedel, Walburga, Hellmich, Martin, Papachristou, Irini, Toepelt, Karin, Draube, Andreas, Heukamp, Lukas, Buettner, Reinhard, Ko, Yon D, Ullrich, Roland T, Smit, Egbert, Boellaard, Ronald, Lammertsma, Adriaan A, Hallek, Michael, Jacobs, Andreas H, Schlesinger, Andreas, Schulte, Karin, Querings, Silvia, Stoelben, Erich, Neumaier, Bernd, Thomas, Roman K, Dietlein, Markus, Wolf, Jürgen
Published in Journal of clinical oncology (01.05.2011)
Published in Journal of clinical oncology (01.05.2011)
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Targeted expression of mutated ALK induces neuroblastoma in transgenic mice
Heukamp, Lukas C, Thor, Theresa, Schramm, Alexander, De Preter, Katleen, Kumps, Candy, De Wilde, Bram, Odersky, Andrea, Peifer, Martin, Lindner, Sven, Spruessel, Annika, Pattyn, Filip, Mestdagh, Pieter, Menten, Björn, Kuhfittig-Kulle, Steffi, Künkele, Annette, König, Katharina, Meder, Lydia, Chatterjee, Sampurna, Ullrich, Roland T, Schulte, Stefanie, Vandesompele, Jo, Speleman, Frank, Büttner, Reinhard, Eggert, Angelika, Schulte, Johannes H
Published in Science translational medicine (04.07.2012)
Published in Science translational medicine (04.07.2012)
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Evolutionary trajectories of small cell lung cancer under therapy
George, Julie, Maas, Lukas, Abedpour, Nima, Cartolano, Maria, Kaiser, Laura, Fischer, Rieke N., Scheel, Andreas H., Weber, Jan-Philipp, Hellmich, Martin, Bosco, Graziella, Volz, Caroline, Mueller, Christian, Dahmen, Ilona, John, Felix, Alves, Cleidson Padua, Werr, Lisa, Panse, Jens Peter, Kirschner, Martin, Engel-Riedel, Walburga, Jürgens, Jessica, Stoelben, Erich, Brockmann, Michael, Grau, Stefan, Sebastian, Martin, Stratmann, Jan A., Kern, Jens, Hummel, Horst-Dieter, Hegedüs, Balazs, Schuler, Martin, Plönes, Till, Aigner, Clemens, Elter, Thomas, Toepelt, Karin, Ko, Yon-Dschun, Kurz, Sylke, Grohé, Christian, Serke, Monika, Höpker, Katja, Hagmeyer, Lars, Doerr, Fabian, Hekmath, Khosro, Strapatsas, Judith, Kambartel, Karl-Otto, Chakupurakal, Geothy, Busch, Annette, Bauernfeind, Franz-Georg, Griesinger, Frank, Luers, Anne, Dirks, Wiebke, Wiewrodt, Rainer, Luecke, Andrea, Rodermann, Ernst, Diel, Andreas, Hagen, Volker, Severin, Kai, Ullrich, Roland T., Reinhardt, Hans Christian, Quaas, Alexander, Bogus, Magdalena, Courts, Cornelius, Nürnberg, Peter, Becker, Kerstin, Achter, Viktor, Büttner, Reinhard, Wolf, Jürgen, Peifer, Martin, Thomas, Roman K.
Published in Nature (London) (28.03.2024)
Published in Nature (London) (28.03.2024)
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Early detection of erlotinib treatment response in NSCLC by 3'-deoxy-3'-[F]-fluoro-L-thymidine ([F]FLT) positron emission tomography (PET)
Ullrich, Roland T, Zander, Thomas, Neumaier, Bernd, Koker, Mirjam, Shimamura, Takeshi, Waerzeggers, Yannic, Borgman, Christa L, Tawadros, Samir, Li, Hongfeng, Sos, Martin L, Backes, Heiko, Shapiro, Geoffrey I, Wolf, Jürgen, Jacobs, Andreas H, Thomas, Roman K, Winkeler, Alexandra
Published in PloS one (12.12.2008)
Published in PloS one (12.12.2008)
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The bispecific immunoligand ULBP2‐aCEA redirects natural killer cells to tumor cells and reveals potent anti‐tumor activity against colon carcinoma
Rothe, Achim, Jachimowicz, Ron D., Borchmann, Sven, Madlener, Marie, Keßler, Jörg, Reiners, Katrin S., Sauer, Maike, Hansen, Hinrich P., Ullrich, Roland T., Chatterjee, Sampurna, Borchmann, Peter, Yazaki, Paul, Koslowsky, Thomas C., Engert, Andreas, Heukamp, Lukas C., Hallek, Michael, Strandmann, Elke Pogge
Published in International journal of cancer (15.06.2014)
Published in International journal of cancer (15.06.2014)
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Somatic rearrangements causing oncogenic ectodomain deletions of FGFR1 in squamous cell lung cancer
Malchers, Florian, Nogova, Lucia, van Attekum, Martijn Ha, Maas, Lukas, Brägelmann, Johannes, Bartenhagen, Christoph, Girard, Luc, Bosco, Graziella, Dahmen, Ilona, Michels, Sebastian, Weeden, Clare E, Scheel, Andreas H, Meder, Lydia, Golfmann, Kristina, Schuldt, Philipp, Siemanowski, Janna, Rehker, Jan, Merkelbach-Bruse, Sabine, Menon, Roopika, Gautschi, Oliver, Heuckmann, Johannes M, Brambilla, Elisabeth, Asselin-Labat, Marie-Liesse, Persigehl, Thorsten, Minna, John D, Walczak, Henning, Ullrich, Roland T, Fischer, Matthias, Reinhardt, Hans Christian, Wolf, Jürgen, Büttner, Reinhard, Peifer, Martin, George, Julie, Thomas, Roman K
Published in The Journal of clinical investigation (01.11.2023)
Published in The Journal of clinical investigation (01.11.2023)
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Inhibition of Tumor VEGFR2 Induces Serine 897 EphA2-Dependent Tumor Cell Invasion and Metastasis in NSCLC
Volz, Caroline, Breid, Sara, Selenz, Carolin, Zaplatina, Alina, Golfmann, Kristina, Meder, Lydia, Dietlein, Felix, Borchmann, Sven, Chatterjee, Sampurna, Siobal, Maike, Schöttle, Jakob, Florin, Alexandra, Koker, Mirjam, Nill, Marieke, Ozretić, Luka, Uhlenbrock, Niklas, Smith, Steven, Büttner, Reinhard, Miao, Hui, Wang, Bingcheng, Reinhardt, H. Christian, Rauh, Daniel, Hallek, Michael, Acker-Palmer, Amparo, Heukamp, Lukas C., Ullrich, Roland T.
Published in Cell reports (Cambridge) (28.04.2020)
Published in Cell reports (Cambridge) (28.04.2020)
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Identifying genotype-dependent efficacy of single and combined PI3K- and MAPK-pathway inhibition in cancer
Sos, Martin L, Fischer, Stefanie, Ullrich, Roland, Peifer, Martin, Heuckmann, Johannes M, Koker, Mirjam, Heynck, Stefanie, Stückrath, Isabel, Weiss, Jonathan, Fischer, Florian, Michel, Kathrin, Goel, Aviva, Regales, Lucia, Politi, Katerina A, Perera, Samanthi, Getlik, Matthäus, Heukamp, Lukas C, Ansén, Sascha, Zander, Thomas, Beroukhim, Rameen, Kashkar, Hamid, Shokat, Kevan M, Sellers, William R, Rauh, Daniel, Orr, Christine, Hoeflich, Klaus P, Friedman, Lori, Wong, Kwok-Kin, Pao, William, Thomas, Roman K
Published in Proceedings of the National Academy of Sciences - PNAS (27.10.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (27.10.2009)
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Trophoblast Cell Surface Antigen 2 (TROP2) as a Predictive Bio-Marker for the Therapeutic Efficacy of Sacituzumab Govitecan in Adenocarcinoma of the Esophagus
Hoppe, Sascha, Meder, Lydia, Gebauer, Florian, Ullrich, Roland T, Zander, Thomas, Hillmer, Axel M, Buettner, Reinhard, Plum, Patrick, Puppe, Julian, Malter, Wolfram, Quaas, Alexander
Published in Cancers (30.09.2022)
Published in Cancers (30.09.2022)
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Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions
Sos, Martin L, Michel, Kathrin, Zander, Thomas, Weiss, Jonathan, Frommolt, Peter, Peifer, Martin, Li, Danan, Ullrich, Roland, Koker, Mirjam, Fischer, Florian, Shimamura, Takeshi, Rauh, Daniel, Mermel, Craig, Fischer, Stefanie, Stückrath, Isabel, Heynck, Stefanie, Beroukhim, Rameen, Lin, William, Winckler, Wendy, Shah, Kinjal, LaFramboise, Thomas, Moriarty, Whei F, Hanna, Megan, Tolosi, Laura, Rahnenführer, Jörg, Verhaak, Roel, Chiang, Derek, Getz, Gad, Hellmich, Martin, Wolf, Jürgen, Girard, Luc, Peyton, Michael, Weir, Barbara A, Chen, Tzu-Hsiu, Greulich, Heidi, Barretina, Jordi, Shapiro, Geoffrey I, Garraway, Levi A, Gazdar, Adi F, Minna, John D, Meyerson, Matthew, Wong, Kwok-Kin, Thomas, Roman K
Published in The Journal of clinical investigation (01.06.2009)
Published in The Journal of clinical investigation (01.06.2009)
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Transient Antiangiogenic Treatment Improves Delivery of Cytotoxic Compounds and Therapeutic Outcome in Lung Cancer
CHATTERJEE, Sampurna, WIECZOREK, Caroline, ULLRICH, Roland T, SCHOTTLE, Jakob, SIOBAL, Maike, HINZE, Yvonne, FRANZ, Thomas, FLORIN, Alexandra, ADAMCZAK, Joanna, HEUKAMP, Lukas C, NEUMAIER, Bernd
Published in Cancer research (Chicago, Ill.) (15.05.2014)
Published in Cancer research (Chicago, Ill.) (15.05.2014)
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