1234-[]-3- SUBSTITUTED 1234- TETRAHYDROCYCLOPENTA[]INDOL-3-YL ACETIC ACID DERIVATIVES USEFUL IN THE TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISORDERS
MOODY JEANNE V, ZHU XIUWEN, JONES ROBERT M, ULLMAN BRETT, BUZARD DANIEL J, HAN, SANG DON, LEHMANN JUERG, STIRN SCOTT, KIM, SUN HEE
Year of Publication 25.04.2017
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Year of Publication 25.04.2017
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Synthesis and in Vivo Evaluation of Phenethylpiperazine Amides: Selective 5-Hydroxytryptamine(2A) Receptor Antagonists for the Treatment of Insomnia
Xiong, Yifeng, Ullman, Brett, Choi, Jin-Sun Karoline, Cherrier, Martin, Strah-Pleynet, Sonja, Decaire, Marc, Dosa, Peter I., Feichtinger, Konrad, Teegarden, Bradley R., Frazer, John M., Yoon, Woo H., Shan, Yun, Whelan, Kevin, Hauser, Erin K., Grottick, Andrew J., Semple, Graeme, Al-Shamma, Hussien
Published in Journal of medicinal chemistry (12.08.2010)
Published in Journal of medicinal chemistry (12.08.2010)
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Discovery and Structure−Activity Relationship of 3-Methoxy-N-(3-(1-methyl-1H-pyrazol-5-yl)-4-(2-morpholinoethoxy)phenyl)benzamide (APD791): A Highly Selective 5-Hydroxytryptamine2A Receptor Inverse Agonist for the Treatment of Arterial Thrombosis
Xiong, Yifeng, Teegarden, Bradley R, Choi, Jin-Sun Karoline, Strah-Pleynet, Sonja, Decaire, Marc, Jayakumar, Honnappa, Dosa, Peter I, Casper, Martin D, Pham, Lan, Feichtinger, Konrad, Ullman, Brett, Adams, John, Yuskin, Diane, Frazer, John, Morgan, Michael, Sadeque, Abu, Chen, Weichao, Webb, Robert R, Connolly, Daniel T, Semple, Graeme, Al-Shamma, Hussien
Published in Journal of medicinal chemistry (10.06.2010)
Published in Journal of medicinal chemistry (10.06.2010)
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Journal Article
Synthesis and in Vivo Evaluation of Phenethylpiperazine Amides: Selective 5-Hydroxytryptamine2A Receptor Antagonists for the Treatment of Insomnia
Xiong, Yifeng, Ullman, Brett, Choi, Jin-Sun Karoline, Cherrier, Martin, Strah-Pleynet, Sonja, Decaire, Marc, Dosa, Peter I, Feichtinger, Konrad, Teegarden, Bradley R, Frazer, John M, Yoon, Woo H, Shan, Yun, Whelan, Kevin, Hauser, Erin K, Grottick, Andrew J, Semple, Graeme, Al-Shamma, Hussien
Published in Journal of medicinal chemistry (12.08.2010)
Published in Journal of medicinal chemistry (12.08.2010)
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Fused tricyclic indoles as S1P1 agonists with robust efficacy in animal models of autoimmune disease
Buzard, Daniel J., Han, Sangdon, Lopez, Luis, Kawasaki, Andrew, Moody, Jeanne, Thoresen, Lars, Ullman, Brett, Lehmann, Juerg, Calderon, Imelda, Zhu, Xiuwen, Gharbaoui, Tawfik, Sengupta, Dipanjan, Krishnan, Ashwin, Gao, Yinghong, Edwards, Jeff, Barden, Jeremy, Morgan, Michael, Usmani, Khawja, Chen, Chuan, Sadeque, Abu, Thatte, Jayant, Solomon, Michelle, Fu, Lixia, Whelan, Kevin, Liu, Ling, Al-Shamma, Hussien, Gatlin, Joel, Le, Minh, Xing, Charles, Espinola, Sheryll, Jones, Robert M.
Published in Bioorganic & medicinal chemistry letters (01.07.2012)
Published in Bioorganic & medicinal chemistry letters (01.07.2012)
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Journal Article
Synthesis and in Vivo Evaluation of Phenethylpiperazine Amides: Selective 5-Hydroxytryptamine 2A Receptor Antagonists for the Treatment of Insomnia
Xiong, Yifeng, Ullman, Brett, Choi, Jin-Sun Karoline, Cherrier, Martin, Strah-Pleynet, Sonja, Decaire, Marc, Dosa, Peter I., Feichtinger, Konrad, Teegarden, Bradley R., Frazer, John M., Yoon, Woo H., Shan, Yun, Whelan, Kevin, Hauser, Erin K., Grottick, Andrew J., Semple, Graeme, Al-Shamma, Hussien
Published in Journal of medicinal chemistry (12.08.2010)
Published in Journal of medicinal chemistry (12.08.2010)
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Journal Article
Discovery and Structure−Activity Relationship of 3-Methoxy- N -(3-(1-methyl-1 H -pyrazol-5-yl)-4-(2-morpholinoethoxy)phenyl)benzamide (APD791): A Highly Selective 5-Hydroxytryptamine 2A Receptor Inverse Agonist for the Treatment of Arterial Thrombosis
Xiong, Yifeng, Teegarden, Bradley R., Choi, Jin-Sun Karoline, Strah-Pleynet, Sonja, Decaire, Marc, Jayakumar, Honnappa, Dosa, Peter I., Casper, Martin D., Pham, Lan, Feichtinger, Konrad, Ullman, Brett, Adams, John, Yuskin, Diane, Frazer, John, Morgan, Michael, Sadeque, Abu, Chen, Weichao, Webb, Robert R., Connolly, Daniel T., Semple, Graeme, Al-Shamma, Hussien
Published in Journal of medicinal chemistry (10.06.2010)
Published in Journal of medicinal chemistry (10.06.2010)
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RAPAFUCIN DERIVATIVE COMPOUNDS AND METHODS OF USE THEREOF
Kumar, Puneet, Liu, Jun, Yamamoto, Kana, Semple, Joseph E, Hong, Sam, Sadagopan, Magesh, Ullman, Brett R, Schmitt, Jennifer C
Year of Publication 18.07.2024
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Year of Publication 18.07.2024
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Identification of fused bicyclic heterocycles as potent and selective 5-HT(2A) receptor antagonists for the treatment of insomnia
Xiong, Yifeng, Ullman, Brett, Choi, Jin-Sun Karoline, Cherrier, Martin, Strah-Pleynet, Sonja, Decaire, Marc, Feichtinger, Konrad, Frazer, John M, Yoon, Woo H, Whelan, Kevin, Sanabria, Erin K, Grottick, Andrew J, Al-Shamma, Hussien, Semple, Graeme
Published in Bioorganic & medicinal chemistry letters (01.03.2012)
Published in Bioorganic & medicinal chemistry letters (01.03.2012)
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SUBSTITUTED 1,2,3,4- TETRAHYDROCYCLOPENTA[B]INDOL-3-YL) ACETIC ACID DERIVATIVES USEFUL IN THE TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISORDERS
MOODY JEANNE V, ZHU XIUWEN, JONES ROBERT M, ULLMAN BRETT, BUZARD DANIEL J, HAN, SANG DON, LEHMANN JUERG, STIRN SCOTT, KIM, SUN HEE
Year of Publication 05.04.2011
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Year of Publication 05.04.2011
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Rapafucin derivative compounds and methods of use thereof
Kumar, Puneet, Liu, Jun, Yamamoto, Kana, Semple, Joseph E, Hong, Sam, Sadagopan, Magesh, Ullman, Brett R, Schmitt, Jennifer C
Year of Publication 02.04.2024
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Year of Publication 02.04.2024
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RAPAFUCIN DERIVATIVE COMPOUNDS AND METHODS OF USE THEREOF
SADAGOPAN, Magesh, HONG, Sam, YAMAMOTO, Kana, LIU, Jun, KUMAR, Puneet, SEMPLE, Joseph, E, ULLMAN, Brett, R, SCHMITT, Jennifer, C
Year of Publication 18.10.2023
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Year of Publication 18.10.2023
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