Transcriptional profiling of human microglia reveals grey–white matter heterogeneity and multiple sclerosis-associated changes
van der Poel, Marlijn, Ulas, Thomas, Mizee, Mark R., Hsiao, Cheng-Chih, Miedema, Suzanne S. M., Adelia, Schuurman, Karianne G., Helder, Boy, Tas, Sander W., Schultze, Joachim L., Hamann, Jörg, Huitinga, Inge
Published in Nature communications (13.03.2019)
Published in Nature communications (13.03.2019)
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Journal Article
Cxcr4 distinguishes HSC-derived monocytes from microglia and reveals monocyte immune responses to experimental stroke
Werner, Yves, Mass, Elvira, Ashok Kumar, Praveen, Ulas, Thomas, Händler, Kristian, Horne, Arik, Klee, Kathrin, Lupp, Amelie, Schütz, Dagmar, Saaber, Friederike, Redecker, Christoph, Schultze, Joachim L., Geissmann, Frederic, Stumm, Ralf
Published in Nature neuroscience (01.03.2020)
Published in Nature neuroscience (01.03.2020)
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Journal Article
Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients
Aschenbrenner, Anna C, Mouktaroudi, Maria, Krämer, Benjamin, Oestreich, Marie, Antonakos, Nikolaos, Nuesch-Germano, Melanie, Gkizeli, Konstantina, Bonaguro, Lorenzo, Reusch, Nico, Baßler, Kevin, Saridaki, Maria, Knoll, Rainer, Pecht, Tal, Kapellos, Theodore S, Doulou, Sarandia, Kröger, Charlotte, Herbert, Miriam, Holsten, Lisa, Horne, Arik, Gemünd, Ioanna D, Rovina, Nikoletta, Agrawal, Shobhit, Dahm, Kilian, van Uelft, Martina, Drews, Anna, Lenkeit, Lena, Bruse, Niklas, Gerretsen, Jelle, Gierlich, Jannik, Becker, Matthias, Händler, Kristian, Kraut, Michael, Theis, Heidi, Mengiste, Simachew, De Domenico, Elena, Schulte-Schrepping, Jonas, Seep, Lea, Raabe, Jan, Hoffmeister, Christoph, ToVinh, Michael, Keitel, Verena, Rieke, Gereon, Talevi, Valentina, Skowasch, Dirk, Aziz, N Ahmad, Pickkers, Peter, van de Veerdonk, Frank L, Netea, Mihai G, Schultze, Joachim L, Kox, Matthijs, Breteler, Monique M B, Nattermann, Jacob, Koutsoukou, Antonia, Giamarellos-Bourboulis, Evangelos J, Ulas, Thomas
Published in Genome medicine (13.01.2021)
Published in Genome medicine (13.01.2021)
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Therapeutic targeting of macrophages enhances chemotherapy efficacy by unleashing type I interferon response
Salvagno, Camilla, Ciampricotti, Metamia, Tuit, Sander, Hau, Cheei-Sing, van Weverwijk, Antoinette, Coffelt, Seth B., Kersten, Kelly, Vrijland, Kim, Kos, Kevin, Ulas, Thomas, Song, Ji-Ying, Ooi, Chia-Huey, Rüttinger, Dominik, Cassier, Philippe A., Jonkers, Jos, Schultze, Joachim L., Ries, Carola H., de Visser, Karin E.
Published in Nature cell biology (01.04.2019)
Published in Nature cell biology (01.04.2019)
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Journal Article
Innate immune memory in the brain shapes neurological disease hallmarks
Wendeln, Ann-Christin, Degenhardt, Karoline, Kaurani, Lalit, Gertig, Michael, Ulas, Thomas, Jain, Gaurav, Wagner, Jessica, Häsler, Lisa M., Wild, Katleen, Skodras, Angelos, Blank, Thomas, Staszewski, Ori, Datta, Moumita, Centeno, Tonatiuh Pena, Capece, Vincenzo, Islam, Md. Rezaul, Kerimoglu, Cemil, Staufenbiel, Matthias, Schultze, Joachim L., Beyer, Marc, Prinz, Marco, Jucker, Mathias, Fischer, André, Neher, Jonas J.
Published in Nature (London) (19.04.2018)
Published in Nature (London) (19.04.2018)
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Journal Article
Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19
Bernardes, Joana P., Tran, Florian, Best, Lena, Bordoni, Dora, Josephs-Spaulding, Jonathan, Köhler, Philipp, Künstner, Axel, Rosati, Elisa, Bacher, Petra, Bruse, Niklas, Franzenburg, Sören, Frey, Norbert, Fuß, Janina, Glück, Andreas, Hamm, Jacob, Imm, Simon, Kaiser, Sina, Lange, Christoph, Laue, Georg, Marinos, Georgios, Pickkers, Peter, Rabe, Klaus F., Renz, Alina, Röcken, Christoph, Rupp, Jan, Schaffarzyk, Annika, Scheffold, Alexander, Schulte-Schrepping, Jonas, Skowasch, Dirk, Ulas, Thomas, Wandinger, Klaus-Peter, Wittig, Michael, Zimmermann, Johannes, Busch, Hauke, Hoyer, Bimba F., Kaleta, Christoph, Heyckendorf, Jan, Rybniker, Jan, Schultze, Joachim L., Rosenstiel, Philip, Banovich, Nicholas E., Desai, Tushar, Eickelberg, Oliver, Haniffa, Muzlifa, Horvath, Peter, Kropski, Jonathan A., Lafyatis, Robert, Meyer, Kerstin, Nawijn, Martijn C., Nikolic, Marko, Ordovas Montanes, Jose, Pe’er, Dana, Tata, Purushothama Rao, Rawlins, Emma, Regev, Aviv, Reyfman, Paul, Samakovlis, Christos, Schultze, Joachim, Shalek, Alex, Shepherd, Douglas, Spence, Jason, Theis, Fabian, van den Berge, Maarten, von Papen, Michael, Whitsett, Jeffrey, Angelov, Angel, Bals, Robert, Bonifacio, Ezio, Colme-Tatche, Maria, Diefenbach, Andreas, Dilthey, Alexander, Fischer, Nicole, Gagneur, Julien, Goesmann, Alexander, Kallies, René, Kehr, Birte, Keller, Andreas, Kim-Hellmuth, Sarah, Korbel, Jan O., Kurth, Ingo, Landthaler, Markus, Li, Yang, Ludwig, Kerstin, Makarewicz, Oliwia, Nöthen, Markus, Nürnberg, Peter, Ohler, Uwe, Overmann, Jörg, Peter, Silke, Pfeffer, Klaus, Poetsch, Anna R., Rajewsky, Niklaus, Ralser, Markus, Saliba, Antoine-Emmanuel, Schulte, Eva-Christina, Sczyrba, Alexander, Stegle, Oliver, Stoye, Jens, von Kleist, Max, Walker, Andreas
Published in Immunity (15.12.2020)
Published in Immunity (15.12.2020)
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Web Resource
Mitochondrial metabolism coordinates stage-specific repair processes in macrophages during wound healing
Willenborg, Sebastian, Sanin, David E., Jais, Alexander, Ding, Xiaolei, Ulas, Thomas, Nüchel, Julian, Popović, Milica, MacVicar, Thomas, Langer, Thomas, Schultze, Joachim L., Gerbaulet, Alexander, Roers, Axel, Pearce, Edward J., Brüning, Jens C., Trifunovic, Aleksandra, Eming, Sabine A.
Published in Cell metabolism (07.12.2021)
Published in Cell metabolism (07.12.2021)
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Journal Article
Impaired neurogenesis alters brain biomechanics in a neuroprogenitor-based genetic subtype of congenital hydrocephalus
Duy, Phan Q., Weise, Stefan C., Marini, Claudia, Li, Xiao-Jun, Liang, Dan, Dahl, Peter J., Ma, Shaojie, Spajic, Ana, Dong, Weilai, Juusola, Jane, Kiziltug, Emre, Kundishora, Adam J., Koundal, Sunil, Pedram, Maysam Z., Torres-Fernández, Lucia A., Händler, Kristian, De Domenico, Elena, Becker, Matthias, Ulas, Thomas, Juranek, Stefan A., Cuevas, Elisa, Hao, Le Thi, Jux, Bettina, Sousa, André M. M., Liu, Fuchen, Kim, Suel-Kee, Li, Mingfeng, Yang, Yiying, Takeo, Yutaka, Duque, Alvaro, Nelson-Williams, Carol, Ha, Yonghyun, Selvaganesan, Kartiga, Robert, Stephanie M., Singh, Amrita K., Allington, Garrett, Furey, Charuta G., Timberlake, Andrew T., Reeves, Benjamin C., Smith, Hannah, Dunbar, Ashley, DeSpenza, Tyrone, Goto, June, Marlier, Arnaud, Moreno-De-Luca, Andres, Yu, Xin, Butler, William E., Carter, Bob S., Lake, Evelyn M. R., Constable, R. Todd, Rakic, Pasko, Lin, Haifan, Deniz, Engin, Benveniste, Helene, Malvankar, Nikhil S., Estrada-Veras, Juvianee I., Walsh, Christopher A., Alper, Seth L., Schultze, Joachim L., Paeschke, Katrin, Doetzlhofer, Angelika, Wulczyn, F. Gregory, Jin, Sheng Chih, Lifton, Richard P., Sestan, Nenad, Kolanus, Waldemar, Kahle, Kristopher T.
Published in Nature neuroscience (01.04.2022)
Published in Nature neuroscience (01.04.2022)
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Journal Article
Transcriptome-Based Network Analysis Reveals a Spectrum Model of Human Macrophage Activation
Xue, Jia, Schmidt, Susanne V., Sander, Jil, Draffehn, Astrid, Krebs, Wolfgang, Quester, Inga, De Nardo, Dominic, Gohel, Trupti D., Emde, Martina, Schmidleithner, Lisa, Ganesan, Hariharasudan, Nino-Castro, Andrea, Mallmann, Michael R., Labzin, Larisa, Theis, Heidi, Kraut, Michael, Beyer, Marc, Latz, Eicke, Freeman, Tom C., Ulas, Thomas, Schultze, Joachim L.
Published in Immunity (Cambridge, Mass.) (20.02.2014)
Published in Immunity (Cambridge, Mass.) (20.02.2014)
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The gut microbiota is associated with the small intestinal paracellular permeability and the development of the immune system in healthy children during the first two years of life
Kaczmarczyk, Mariusz, Löber, Ulrike, Adamek, Karolina, Węgrzyn, Dagmara, Skonieczna-Żydecka, Karolina, Malinowski, Damian, Łoniewski, Igor, Markó, Lajos, Ulas, Thomas, Forslund, Sofia K, Łoniewska, Beata
Published in Journal of translational medicine (28.04.2021)
Published in Journal of translational medicine (28.04.2021)
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Journal Article
Chemotherapy-induced antitumor immunity requires formyl peptide receptor 1
Vacchelli, Erika, Ma, Yuting, Baracco, Elisa E., Sistigu, Antonella, Enot, David P., Pietrocola, Federico, Yang, Heng, Adjemian, Sandy, Chaba, Kariman, Semeraro, Michaela, Signore, Michele, De Ninno, Adele, Lucarini, Valeria, Peschiaroli, Francesca, Businaro, Luca, Gerardino, Annamaria, Manic, Gwenola, Ulas, Thomas, Günther, Patrick, Schultze, Joachim L., Kepp, Oliver, Stoll, Gautier, Lefebvre, Céline, Mulot, Claire, Castoldi, Francesca, Rusakiewicz, Sylvie, Ladoire, Sylvain, Apetoh, Lionel, Pedro, José Manuel Bravo-San, Lucattelli, Monica, Delarasse, Cécile, Boige, Valérie, Ducreux, Michel, Delaloge, Suzette, Borg, Christophe, André, Fabrice, Schiavoni, Giovanna, Vitale, Ilio, Laurent-Puig, Pierre, Mattei, Fabrizio, Zitvogel, Laurence, Kroemer, Guido
Published in Science (American Association for the Advancement of Science) (20.11.2015)
Published in Science (American Association for the Advancement of Science) (20.11.2015)
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Journal Article
Stroke target identification guided by astrocyte transcriptome analysis
Rakers, Cordula, Schleif, Melvin, Blank, Nelli, Matušková, Hana, Ulas, Thomas, Händler, Kristian, Torres, Santiago Valle, Schumacher, Toni, Tai, Khalid, Schultze, Joachim L., Jackson, Walker S., Petzold, Gabor C.
Published in Glia (01.04.2019)
Published in Glia (01.04.2019)
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Journal Article
S100A8 and S100A9 Are Important for Postnatal Development of Gut Microbiota and Immune System in Mice and Infants
Willers, Maike, Ulas, Thomas, Völlger, Lena, Vogl, Thomas, Heinemann, Anna S., Pirr, Sabine, Pagel, Julia, Fehlhaber, Beate, Halle, Olga, Schöning, Jennifer, Schreek, Sabine, Löber, Ulrike, Essex, Morgan, Hombach, Peter, Graspeuntner, Simon, Basic, Marijana, Bleich, Andre, Cloppenborg-Schmidt, Katja, Künzel, Sven, Jonigk, Danny, Rupp, Jan, Hansen, Gesine, Förster, Reinhold, Baines, John F., Härtel, Christoph, Schultze, Joachim L., Forslund, Sofia K., Roth, Johannes, Viemann, Dorothee
Published in Gastroenterology (New York, N.Y. 1943) (01.12.2020)
Published in Gastroenterology (New York, N.Y. 1943) (01.12.2020)
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Cellular Differentiation of Human Monocytes Is Regulated by Time-Dependent Interleukin-4 Signaling and the Transcriptional Regulator NCOR2
Sander, Jil, Schmidt, Susanne V., Cirovic, Branko, McGovern, Naomi, Papantonopoulou, Olympia, Hardt, Anna-Lena, Aschenbrenner, Anna C., Kreer, Christoph, Quast, Thomas, Xu, Alexander M., Schmidleithner, Lisa M., Theis, Heidi, Thi Huong, Lan Do, Sumatoh, Hermi Rizal Bin, Lauterbach, Mario A.R., Schulte-Schrepping, Jonas, Günther, Patrick, Xue, Jia, Baßler, Kevin, Ulas, Thomas, Klee, Kathrin, Katzmarski, Natalie, Herresthal, Stefanie, Krebs, Wolfgang, Martin, Bianca, Latz, Eicke, Händler, Kristian, Kraut, Michael, Kolanus, Waldemar, Beyer, Marc, Falk, Christine S., Wiegmann, Bettina, Burgdorf, Sven, Melosh, Nicholas A., Newell, Evan W., Ginhoux, Florent, Schlitzer, Andreas, Schultze, Joachim L.
Published in Immunity (Cambridge, Mass.) (19.12.2017)
Published in Immunity (Cambridge, Mass.) (19.12.2017)
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Journal Article
Cannabinoid receptor 2 is necessary to induce toll‐like receptor‐mediated microglial activation
Reusch, Nico, Ravichandran, Kishore Aravind, Olabiyi, Bolanle Fatimat, Komorowska‐Müller, Joanna Agnieszka, Hansen, Jan N., Ulas, Thomas, Beyer, Marc, Zimmer, Andreas, Schmöle, Anne‐Caroline
Published in Glia (01.01.2022)
Published in Glia (01.01.2022)
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Journal Article
Human glioblastoma-associated microglia/monocytes express a distinct RNA profile compared to human control and murine samples
Szulzewsky, Frank, Arora, Sonali, de Witte, Lot, Ulas, Thomas, Markovic, Darko, Schultze, Joachim L., Holland, Eric C., Synowitz, Michael, Wolf, Susanne A., Kettenmann, Helmut
Published in Glia (01.08.2016)
Published in Glia (01.08.2016)
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Urban living in healthy Tanzanians is associated with an inflammatory status driven by dietary and metabolic changes
Temba, Godfrey S., Kullaya, Vesla, Pecht, Tal, Mmbaga, Blandina T., Aschenbrenner, Anna C., Ulas, Thomas, Kibiki, Gibson, Lyamuya, Furaha, Boahen, Collins K., Kumar, Vinod, Joosten, Leo A. B., Schultze, Joachim L., van der Ven, Andre J., Netea, Mihai G., de Mast, Quirijn
Published in Nature immunology (01.03.2021)
Published in Nature immunology (01.03.2021)
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Transcriptome-based profiling of yolk sac-derived macrophages reveals a role for Irf8 in macrophage maturation
Hagemeyer, Nora, Kierdorf, Katrin, Frenzel, Kathrin, Xue, Jia, Ringelhan, Marc, Abdullah, Zeinab, Godin, Isabelle, Wieghofer, Peter, Costa Jordão, Marta Joana, Ulas, Thomas, Yorgancioglu, Gülden, Rosenbauer, Frank, Knolle, Percy A, Heikenwalder, Mathias, Schultze, Joachim L, Prinz, Marco
Published in The EMBO journal (15.08.2016)
Published in The EMBO journal (15.08.2016)
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BCL7A‐containing SWI/SNF/BAF complexes modulate mitochondrial bioenergetics during neural progenitor differentiation
Wischhof, Lena, Lee, Hang‐Mao, Tutas, Janine, Overkott, Clemens, Tedt, Eileen, Stork, Miriam, Peitz, Michael, Brüstle, Oliver, Ulas, Thomas, Händler, Kristian, Schultze, Joachim L, Ehninger, Dan, Nicotera, Pierluigi, Salomoni, Paolo, Bano, Daniele
Published in The EMBO journal (01.12.2022)
Published in The EMBO journal (01.12.2022)
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