Inhibition of the spindle assembly checkpoint kinase TTK enhances the efficacy of docetaxel in a triple-negative breast cancer model
Maia, A.R.R., de Man, J., Boon, U., Janssen, A., Song, J.-Y., Omerzu, M., Sterrenburg, J.G., Prinsen, M.B.W., Willemsen-Seegers, N., de Roos, J.A.D.M., van Doornmalen, A.M., Uitdehaag, J.C.M., Kops, G.J.P.L., Jonkers, J., Buijsman, R.C., Zaman, G.J.R., Medema, R.H.
Published in Annals of oncology (01.10.2015)
Published in Annals of oncology (01.10.2015)
Get full text
Journal Article
Mechanistic differentiation of PI3K/mTOR, Aurora kinase and EZH2 inhibitor classes by comparative cancer cell line profiling
Uitdehaag, J.C.M, De Roos, J.A.D.M, Prinsen, M.B.W, De Vetter, J.R.F, Dylus, J, Van Doornmalen, A.M, Van Gerwen, S.J.C, De Man, J, Buijsman, R.C, Zaman, G.J.R
Published in European journal of cancer (1990) (01.07.2016)
Published in European journal of cancer (1990) (01.07.2016)
Get full text
Journal Article
104 Identification of inhibitors of tryptophan metabolizing enzymes for cancer immunotherapy by high-throughput screening
Zaman, G, Uitdehaag, J.C.M, van Gerwen, S, Seegers, N, van Doornmalen, A.M, de Man, J, Buijsman, R.C
Published in European journal of cancer (1990) (01.11.2014)
Published in European journal of cancer (1990) (01.11.2014)
Get full text
Journal Article
349 Synergistic drug combinations that target beta-catenin-driven and MYC-driven cancers
Uitdehaag, J.C.M, Spijkers-Hagelstein, J.A.P, de Roos, J.A.D.M, van Doornmalen, A.M, Prinsen, M.B.W, de Man, J, Buijsman, R.C, Zaman, G.J.R
Published in European journal of cancer (1990) (01.11.2014)
Published in European journal of cancer (1990) (01.11.2014)
Get full text
Journal Article
Cell panel profiling of pre-clinical and clinical anti-cancer agents reveals conserved therapeutic clusters and differentiates the mechanism of action of different PI3K/mTOR, Aurora kinase and EZH2 inhibitors
Uitdehaag, J.C.M, De Roos, J.A.D.M, Prinsen, M.B.W, Willemsen-Seegers, N, De Vetter, J.R.F, Dylus, J, Van Doornmalen, A.M, Kooijman, J, Sawa, M, Van Gerwen, S.J.C, De Man, J, Buijsman, R.C, Zaman, G.J.R
Published in European journal of cancer (1990) (01.12.2016)
Published in European journal of cancer (1990) (01.12.2016)
Get full text
Journal Article
655: Identification of new synergistic drug combinations on basis of cell panel profiling
Uitdehaag, J.C.M, De Roos, J.A.D.M, Spijkers-Hagelstein, J.A.P, Van Doornmalen, A.M, Prinsen, M.B.W, De Man, J, Buijsman, R.C, Zaman, G.J.R
Published in European journal of cancer (1990) (01.07.2014)
Published in European journal of cancer (1990) (01.07.2014)
Get full text
Journal Article
580 - Mechanistic differentiation of PI3K/mTOR, Aurora kinase and EZH2 inhibitor classes by comparative cancer cell line profiling
Uitdehaag, J.C.M., De Roos, J.A.D.M., Prinsen, M.B.W., De Vetter, J.R.F., Dylus, J., Van Doornmalen, A.M., Van Gerwen, S.J.C., De Man, J., Buijsman, R.C., Zaman, G.J.R.
Published in European journal of cancer (1990) (01.07.2016)
Published in European journal of cancer (1990) (01.07.2016)
Get full text
Journal Article
52 - Cell panel profiling of pre-clinical and clinical anti-cancer agents reveals conserved therapeutic clusters and differentiates the mechanism of action of different PI3K/mTOR, Aurora kinase and EZH2 inhibitors
Uitdehaag, J.C.M., De Roos, J.A.D.M., Prinsen, M.B.W., Willemsen-Seegers, N., De Vetter, J.R.F., Dylus, J., Van Doornmalen, A.M., Kooijman, J., Sawa, M., Van Gerwen, S.J.C., De Man, J., Buijsman, R.C., Zaman, G.J.R.
Published in European journal of cancer (1990) (01.12.2016)
Published in European journal of cancer (1990) (01.12.2016)
Get full text
Journal Article
PO-484 Development of a two-step screening-and-confirmation approach to efficiently identify synergistic drug combinations with the PARP inhibitor niraparib
Prinsen, MBW, Vetter, JRF De, Dylus, J, Roos, JADMDe, Gerwen, SJC Van, Buijsman, RC, UItdehaag, JCM
Published in ESMO open (01.07.2018)
Published in ESMO open (01.07.2018)
Get full text
Journal Article
PO-456 Cell line panel profiling of all clinically approved kinase inhibitors for cancer treatment
Kooijman, JJ, Uitdehaag, JCM, Roos, JADMDe, Vetter, JRF De, Prinsen, MBW, Dylus, J, Man, J De, Gerwen, SJC Van, Buijsman, RC, Zaman, GJR
Published in ESMO open (01.07.2018)
Published in ESMO open (01.07.2018)
Get full text
Journal Article