Effects of the dual PPAR-α/γ agonist aleglitazar on glycaemic control and organ protection in the Zucker diabetic fatty rat
Bénardeau, A., Verry, P., Atzpodien, E.-A., Funk, J. M., Meyer, M., Mizrahi, J., Winter, M., Wright, M. B., Uhles, S., Sebokova, E.
Published in Diabetes, obesity & metabolism (01.02.2013)
Published in Diabetes, obesity & metabolism (01.02.2013)
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Journal Article
Taspoglutide, a novel human once-weekly GLP-1 analogue, protects pancreatic β-cells in vitro and preserves islet structure and function in the Zucker diabetic fatty rat in vivo
Uhles, S, Wang, H, Bénardeau, A, Prummer, M, Brecheisen, M, Sewing, S, Tobalina, L, Bosco, D, Wollheim, C.B, Migliorini, C, Sebokova, E
Published in Diabetes, obesity & metabolism (01.04.2011)
Published in Diabetes, obesity & metabolism (01.04.2011)
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Journal Article
Short-term regulation of insulin gene transcription
Leibiger, Barbara, Moede, T, Uhles, S, Berggren, P O, Leibiger, I B
Published in Biochemical Society transactions (01.04.2002)
Published in Biochemical Society transactions (01.04.2002)
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Journal Article
Unimolecular dual incretins maximize metabolic benefits in rodents, monkeys, and humans
Finan, Brian, Ma, Tao, Ottaway, Nickki, Müller, Timo D, Habegger, Kirk M, Heppner, Kristy M, Kirchner, Henriette, Holland, Jenna, Hembree, Jazzminn, Raver, Christine, Lockie, Sarah H, Smiley, David L, Gelfanov, Vasily, Yang, Bin, Hofmann, Susanna, Bruemmer, Dennis, Drucker, Daniel J, Pfluger, Paul T, Perez-Tilve, Diego, Gidda, Jaswant, Vignati, Louis, Zhang, Lianshan, Hauptman, Jonathan B, Lau, Michele, Brecheisen, Mathieu, Uhles, Sabine, Riboulet, William, Hainaut, Emmanuelle, Sebokova, Elena, Conde-Knape, Karin, Konkar, Anish, DiMarchi, Richard D, Tschöp, Matthias H
Published in Science translational medicine (30.10.2013)
Published in Science translational medicine (30.10.2013)
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Journal Article
Interferon alpha-induced apoptosis in tumor cells is mediated through the phosphoinositide 3-kinase/mammalian target of rapamycin signaling pathway
Thyrell, Lena, Hjortsberg, Linn, Arulampalam, Velmurugesan, Panaretakis, Theocharis, Uhles, Sabine, Dagnell, Markus, Zhivotovsky, Boris, Leibiger, Ingo, Grandér, Dan, Pokrovskaja, Katja
Published in The Journal of biological chemistry (04.06.2004)
Published in The Journal of biological chemistry (04.06.2004)
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Journal Article
Isoform-Specific Insulin Receptor Signaling Involves Different Plasma Membrane Domains
Uhles, Sabine, Moede, Tilo, Leibiger, Barbara, Berggren, Per-Olof, Leibiger, Ingo B.
Published in The Journal of cell biology (22.12.2003)
Published in The Journal of cell biology (22.12.2003)
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Journal Article
Effects of the dual PPAR-[alpha]/[gamma] agonist aleglitazar on glycaemic control and organ protection in the Zucker diabetic fatty rat
Bénardeau, A, Verry, P, Atzpodien, E.-A, Funk, J. M, Meyer, M, Mizrahi, J, Winter, M, Wright, M. B, Uhles, S, Sebokova, E
Published in Diabetes, obesity & metabolism (01.02.2013)
Published in Diabetes, obesity & metabolism (01.02.2013)
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Journal Article
Selective gene activation by spatial segregation of insulin receptor B signaling
Uhles, Sabine, Moede, Tilo, Leibiger, Barbara, Berggren, Per-Olof, Leibiger, Ingo B
Published in The FASEB journal (01.05.2007)
Published in The FASEB journal (01.05.2007)
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Journal Article
Apolipoprotein CIII Promotes Ca2+-Dependent β Cell Death in Type 1 Diabetes
Juntti-Berggren, Lisa, Refai, Essam, Appelskog, Ioulia, Andersson, Mats, Imreh, Gabriela, Dekki, Nancy, Uhles, Sabine, Yu, Lina, Griffiths, William J., Zaitsev, Sergei, Leibiger, Ingo, Yang, Shao-Nian, Olivecronal, Gunilla, Jörnvall, Hans, Berggren, Per-Olof, Spiegelman, Bruce M.
Published in Proceedings of the National Academy of Sciences - PNAS (06.07.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (06.07.2004)
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Journal Article
Insulin-feedback via PI3K-C2alpha activated PKBalpha/Akt1 is required for glucose-stimulated insulin secretion
Leibiger, Barbara, Moede, Tilo, Uhles, Sabine, Barker, Christopher J, Creveaux, Marion, Domin, Jan, Berggren, Per-Olof, Leibiger, Ingo B
Published in The FASEB journal (01.06.2010)
Published in The FASEB journal (01.06.2010)
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Journal Article
Apolipoprotein CIII promotes Ca super(2+)-dependent beta cell death in type 1 diabetes
Juntti-Berggren, L, Refai, E, Appelskog, I, Andersson, M, Imreh, G, Dekki, N, Uhles, S, Yu, L, Griffiths, W J, Zaitsev, S, Leibiger, I, Yang, S-N, Olivecrona, G, Joernvall, H, Berggren, P-O
Published in Proceedings of the National Academy of Sciences - PNAS (06.07.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (06.07.2004)
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Journal Article
The 14-3-3 protein translates the NA+,K+-ATPase {alpha}1-subunit phosphorylation signal into binding and activation of phosphoinositide 3-kinase during endocytosis
Efendiev, Riad, Chen, Zongpei, Krmar, Rafael T, Uhles, Sabine, Katz, Adrian I, Pedemonte, Carlos H, Bertorello, Alejandro M
Published in The Journal of biological chemistry (22.04.2005)
Published in The Journal of biological chemistry (22.04.2005)
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Journal Article
Removal of Ca super(2+) Channel beta sub(3) Subunit Enhances Ca super(2+) Oscillation Frequency and Insulin Exocytosis
Berggren, P-O, Yang, S-N, Murakami, M, Efanov, A M, Uhles, S, Koehler, M, Moede, T, Fernstroem, A, Appelskog, IB, Aspinwall, CA, Zaitsev, S V, Larsson, O, De Vargas, LM, Fecher-Trost, C, Weissgerber, P, Ludwig, A, Leibiger, B, Juntti-Berggren, L, Barker, C J, Gromada, J, Freichel, M, Leibiger, IB, Flockerzi, V
Published in Cell (01.10.2004)
Published in Cell (01.10.2004)
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Journal Article
Insulin-stimulated PI(3,4)P2 production by PI3K-C2α and activation of glucokinase gene transcription in pancreatic beta cells
Leibiger, B, Moede, T, Barker, CJ, Uhles, S, Domin, J, Berggren, PO, Leibiger, IB
Published in DIABETOLOGIA (2008)
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Published in DIABETOLOGIA (2008)
Conference Proceeding
Selective insulin signaling in pancreatic beta cells involves different classes of PI3 kinases
Leibiger, B, Uhles, S, Moede, T, Domin, J, Berggren, PO, Leibiger, IB
Published in DIABETOLOGIA (2007)
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Published in DIABETOLOGIA (2007)
Conference Proceeding
Removal of Ca2+ channel beta3 subunit enhances Ca2+ oscillation frequency and insulin exocytosis
Berggren, Per-Olof, Yang, Shao-Nian, Murakami, Manabu, Efanov, Alexander M, Uhles, Sabine, Köhler, Martin, Moede, Tilo, Fernström, Andreas, Appelskog, Ioulia B, Aspinwall, Craig A, Zaitsev, Sergei V, Larsson, Olof, de Vargas, Lina Moitoso, Fecher-Trost, Claudia, Weissgerber, Petra, Ludwig, Andreas, Leibiger, Barbara, Juntti-Berggren, Lisa, Barker, Christopher J, Gromada, Jesper, Freichel, Marc, Leibiger, Ingo B, Flockerzi, Veit
Published in Cell (15.10.2004)
Published in Cell (15.10.2004)
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Journal Article