Comparative study between deep learning and QSAR classifications for TNBC inhibitors and novel GPCR agonist discovery
Tsou, Lun K., Yeh, Shiu-Hwa, Ueng, Shau-Hua, Chang, Chun-Ping, Song, Jen-Shin, Wu, Mine-Hsine, Chang, Hsiao-Fu, Chen, Sheng-Ren, Shih, Chuan, Chen, Chiung-Tong, Ke, Yi-Yu
Published in Scientific reports (08.10.2020)
Published in Scientific reports (08.10.2020)
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N-Heterocyclic Carbene Boryl Radicals: A New Class of Boron-Centered Radical
Ueng, Shau-Hua, Solovyev, Andrey, Yuan, Xinting, Geib, Steven J, Fensterbank, Louis, Lacôte, Emmanuel, Malacria, Max, Newcomb, Martin, Walton, John C, Curran, Dennis P
Published in Journal of the American Chemical Society (12.08.2009)
Published in Journal of the American Chemical Society (12.08.2009)
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EPR Studies of the Generation, Structure, and Reactivity of N-Heterocyclic Carbene Borane Radicals
Walton, John C, Brahmi, Malika Makhlouf, Fensterbank, Louis, Lacôte, Emmanuel, Malacria, Max, Chu, Qianli, Ueng, Shau-Hua, Solovyev, Andrey, Curran, Dennis P
Published in Journal of the American Chemical Society (24.02.2010)
Published in Journal of the American Chemical Society (24.02.2010)
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Complexes of Borane and N-Heterocyclic Carbenes: A New Class of Radical Hydrogen Atom Donor
Ueng, Shau-Hua, Makhlouf Brahmi, Malika, Derat, Étienne, Fensterbank, Louis, Lacôte, Emmanuel, Malacria, Max, Curran, Dennis P
Published in Journal of the American Chemical Society (06.08.2008)
Published in Journal of the American Chemical Society (06.08.2008)
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Ionic and Organometallic Reductions with N-Heterocyclic Carbene Boranes
Chu, Qianli, Makhlouf Brahmi, Malika, Solovyev, Andrey, Ueng, Shau-Hua, Curran, Dennis P., Malacria, Max, Fensterbank, Louis, Lacôte, Emmanuel
Published in Chemistry : a European journal (07.12.2009)
Published in Chemistry : a European journal (07.12.2009)
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Identification of Substituted Naphthotriazolediones as Novel Tryptophan 2,3-Dioxygenase (TDO) Inhibitors through Structure-Based Virtual Screening
Wu, Jian-Sung, Lin, Shu-Yu, Liao, Fang-Yu, Hsiao, Wen-Chi, Lee, Lung-Chun, Peng, Yi-Hui, Hsieh, Chia-Ling, Wu, Mine-Hsine, Song, Jen-Shin, Yueh, Andrew, Chen, Chun-Hwa, Yeh, Shiu-Hwa, Liu, Chia-Yeh, Lin, Shu-Yi, Yeh, Teng-Kuang, Hsu, John T.-A., Shih, Chuan, Ueng, Shau-Hua, Hung, Ming-Shiu, Wu, Su-Ying
Published in Journal of medicinal chemistry (08.10.2015)
Published in Journal of medicinal chemistry (08.10.2015)
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Boryltrihydroborate: Synthesis, Structure, and Reactivity as a Reductant in Ionic, Organometallic, and Radical Reactions
Nozaki, Kyoko, Aramaki, Yoshitaka, Yamashita, Makoto, Ueng, Shau-Hua, Malacria, Max, Lacôte, Emmanuel, Curran, Dennis P.
Published in Journal of the American Chemical Society (25.08.2010)
Published in Journal of the American Chemical Society (25.08.2010)
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Convallatoxin enhance the ligand-induced mu-opioid receptor endocytosis and attenuate morphine antinociceptive tolerance in mice
Chao, Po-Kuan, Chang, Hsiao-Fu, Ou, Li-Chin, Chuang, Jian-Ying, Lee, Pin-Tse, Chang, Wan-Ting, Chen, Shu-Chun, Ueng, Shau-Hua, Hsu, John Tsu-An, Tao, Pao-Luh, Law, Ping-Yee, Loh, Horace H., Yeh, Shiu-Hwa
Published in Scientific reports (20.02.2019)
Published in Scientific reports (20.02.2019)
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Estimated Rate Constants for Hydrogen Abstraction from N-Heterocyclic Carbene−Borane Complexes by an Alkyl Radical
Solovyev, Andrey, Ueng, Shau-Hua, Monot, Julien, Fensterbank, Louis, Malacria, Max, Lacôte, Emmanuel, Curran, Dennis P
Published in Organic letters (02.07.2010)
Published in Organic letters (02.07.2010)
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Using a Threading-Followed-by-Swelling Approach to Synthesize [2]Rotaxanes
Ko, Jia-Ling, Ueng, Shau-Hua, Chiu, Ching-Wei, Lai, Chien-Chen, Liu, Yi-Hung, Peng, Shie-Ming, Chiu, Sheng-Hsien
Published in Chemistry : a European journal (18.06.2010)
Published in Chemistry : a European journal (18.06.2010)
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Important Hydrogen Bond Networks in Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitor Design Revealed by Crystal Structures of Imidazoleisoindole Derivatives with IDO1
Peng, Yi-Hui, Ueng, Shau-Hua, Tseng, Chen-Tso, Hung, Ming-Shiu, Song, Jen-Shin, Wu, Jian-Sung, Liao, Fang-Yu, Fan, Yu-Shiou, Wu, Mine-Hsine, Hsiao, Wen-Chi, Hsueh, Ching-Cheng, Lin, Shu-Yu, Cheng, Chia-Yi, Tu, Chih-Hsiang, Lee, Lung-Chun, Cheng, Ming-Fu, Shia, Kak-Shan, Shih, Chuan, Wu, Su-Ying
Published in Journal of medicinal chemistry (14.01.2016)
Published in Journal of medicinal chemistry (14.01.2016)
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Analysis of structure–activity relationship of indol-3-yl-N-phenylcarbamic amides as potent STING inhibitors
Chang, Po-Wei, Wang, Jing-Ya, Wang, Wan-Ping, Huang, Wei-Cheng, Wu, Mine-Hsine, Song, Jen-Shin, Chen, Liuh-Yow, Tung, Chun-Wei, Chi, Ya-Hui, Ueng, Shau-Hua
Published in Bioorganic & medicinal chemistry (15.11.2023)
Published in Bioorganic & medicinal chemistry (15.11.2023)
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Unique Sulfur–Aromatic Interactions Contribute to the Binding of Potent Imidazothiazole Indoleamine 2,3-Dioxygenase Inhibitors
Peng, Yi-Hui, Liao, Fang-Yu, Tseng, Chen-Tso, Kuppusamy, Ramajayam, Li, An-Siou, Chen, Chi-Han, Fan, Yu-Shiou, Wang, Sing-Yi, Wu, Mine-Hsine, Hsueh, Ching-Cheng, Chang, Jia-Yu, Lee, Lung-Chun, Shih, Chuan, Shia, Kak-Shan, Yeh, Teng-Kuang, Hung, Ming-Shiu, Kuo, Ching-Chuan, Song, Jen-Shin, Wu, Su-Ying, Ueng, Shau-Hua
Published in Journal of medicinal chemistry (27.02.2020)
Published in Journal of medicinal chemistry (27.02.2020)
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A dual nociceptin and mu opioid receptor agonist exhibited robust antinociceptive effect with decreased side effects
Hsu, Ying-Ting, Chen, Shen-Ren, Chang, Yung-Chiao, Chang, Hsiao-Fu, Yeh, Teng-Kuang, Chuang, Jian-Ying, Loh, Horace H., Hsieh, Hsing-Pang, Ueng, Shau-Hua, Yeh, Shiu-Hwa
Published in European journal of medicinal chemistry (05.10.2023)
Published in European journal of medicinal chemistry (05.10.2023)
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Phenyl Benzenesulfonylhydrazides Exhibit Selective Indoleamine 2,3-Dioxygenase Inhibition with Potent in Vivo Pharmacodynamic Activity and Antitumor Efficacy
Lin, Shu-Yu, Yeh, Teng-Kuang, Kuo, Ching-Chuan, Song, Jen-Shin, Cheng, Ming-Fu, Liao, Fang-Yu, Chao, Min-Wu, Huang, Han-Li, Chen, Yi-Lin, Yang, Chun-Yu, Wu, Mine-Hsine, Hsieh, Chia-Ling, Hsiao, Wenchi, Peng, Yi-Hui, Wu, Jian-Sung, Lin, Li-Mei, Sun, Manwu, Chao, Yu-Sheng, Shih, Chuan, Wu, Su-Ying, Pan, Shiow-Lin, Hung, Ming-Shiu, Ueng, Shau-Hua
Published in Journal of medicinal chemistry (14.01.2016)
Published in Journal of medicinal chemistry (14.01.2016)
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BPR1M97, a dual mu opioid receptor/nociceptin-orphanin FQ peptide receptor agonist, produces potent antinociceptive effects with safer properties than morphine
Chao, Po-Kuan, Chang, Hsiao-Fu, Chang, Wan-Ting, Yeh, Teng-Kuang, Ou, Li-Chin, Chuang, Jian-Ying, Tsu-An Hsu, John, Tao, Pao-Luh, Loh, Horace H., Shih, Chuan, Ueng, Shau-Hua, Yeh, Shiu-Hwa
Published in Neuropharmacology (01.04.2020)
Published in Neuropharmacology (01.04.2020)
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