The complement system in age-related macular degeneration
Armento, Angela, Ueffing, Marius, Clark, Simon J.
Published in Cellular and molecular life sciences : CMLS (01.05.2021)
Published in Cellular and molecular life sciences : CMLS (01.05.2021)
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Merging organoid and organ-on-a-chip technology to generate complex multi-layer tissue models in a human retina-on-a-chip platform
Achberger, Kevin, Probst, Christopher, Haderspeck, Jasmin, Bolz, Sylvia, Rogal, Julia, Chuchuy, Johanna, Nikolova, Marina, Cora, Virginia, Antkowiak, Lena, Haq, Wadood, Shen, Nian, Schenke-Layland, Katja, Ueffing, Marius, Liebau, Stefan, Loskill, Peter
Published in eLife (27.08.2019)
Published in eLife (27.08.2019)
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Journal Article
A systems biology approach towards understanding and treating non-neovascular age-related macular degeneration
Handa, James T., Bowes Rickman, Cathy, Dick, Andrew D., Gorin, Michael B., Miller, Joan W., Toth, Cynthia A., Ueffing, Marius, Zarbin, Marco, Farrer, Lindsay A.
Published in Nature communications (26.07.2019)
Published in Nature communications (26.07.2019)
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Journal Article
CFAP45 deficiency causes situs abnormalities and asthenospermia by disrupting an axonemal adenine nucleotide homeostasis module
Dougherty, Gerard W., Mizuno, Katsutoshi, Nöthe-Menchen, Tabea, Ikawa, Yayoi, Boldt, Karsten, Ta-Shma, Asaf, Aprea, Isabella, Minegishi, Katsura, Pang, Yuan-Ping, Pennekamp, Petra, Loges, Niki T., Raidt, Johanna, Hjeij, Rim, Wallmeier, Julia, Mussaffi, Huda, Perles, Zeev, Elpeleg, Orly, Rabert, Franziska, Shiratori, Hidetaka, Letteboer, Stef J., Horn, Nicola, Young, Samuel, Strünker, Timo, Stumme, Friederike, Werner, Claudius, Olbrich, Heike, Takaoka, Katsuyoshi, Ide, Takahiro, Twan, Wang Kyaw, Biebach, Luisa, Große-Onnebrink, Jörg, Klinkenbusch, Judith A., Praveen, Kavita, Bracht, Diana C., Höben, Inga M., Junger, Katrin, Gützlaff, Jana, Cindrić, Sandra, Aviram, Micha, Kaiser, Thomas, Memari, Yasin, Dzeja, Petras P., Dworniczak, Bernd, Ueffing, Marius, Roepman, Ronald, Bartscherer, Kerstin, Katsanis, Nicholas, Davis, Erica E., Amirav, Israel, Hamada, Hiroshi, Omran, Heymut
Published in Nature communications (02.11.2020)
Published in Nature communications (02.11.2020)
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Journal Article
Loss of Complement Factor H impairs antioxidant capacity and energy metabolism of human RPE cells
Armento, Angela, Honisch, Sabina, Panagiotakopoulou, Vasiliki, Sonntag, Inga, Jacob, Anke, Bolz, Sylvia, Kilger, Ellen, Deleidi, Michela, Clark, Simon, Ueffing, Marius
Published in Scientific reports (25.06.2020)
Published in Scientific reports (25.06.2020)
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Journal Article
Extensive rewiring of the EGFR network in colorectal cancer cells expressing transforming levels of KRASG13D
Kennedy, Susan A., Jarboui, Mohamed-Ali, Srihari, Sriganesh, Raso, Cinzia, Bryan, Kenneth, Dernayka, Layal, Charitou, Theodosia, Bernal-Llinares, Manuel, Herrera-Montavez, Carlos, Krstic, Aleksandar, Matallanas, David, Kotlyar, Max, Jurisica, Igor, Curak, Jasna, Wong, Victoria, Stagljar, Igor, LeBihan, Thierry, Imrie, Lisa, Pillai, Priyanka, Lynn, Miriam A., Fasterius, Erik, Al-Khalili Szigyarto, Cristina, Breen, James, Kiel, Christina, Serrano, Luis, Rauch, Nora, Rukhlenko, Oleksii, Kholodenko, Boris N., Iglesias-Martinez, Luis F., Ryan, Colm J., Pilkington, Ruth, Cammareri, Patrizia, Sansom, Owen, Shave, Steven, Auer, Manfred, Horn, Nicola, Klose, Franziska, Ueffing, Marius, Boldt, Karsten, Lynn, David J., Kolch, Walter
Published in Nature communications (24.01.2020)
Published in Nature communications (24.01.2020)
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Journal Article
Bardet-Biedl syndrome proteins modulate the release of bioactive extracellular vesicles
Volz, Ann-Kathrin, Frei, Alina, Kretschmer, Viola, de Jesus Domingues, António M., Ketting, Rene F., Ueffing, Marius, Boldt, Karsten, Krämer-Albers, Eva-Maria, May-Simera, Helen L.
Published in Nature communications (27.09.2021)
Published in Nature communications (27.09.2021)
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Journal Article
Transcriptional and metabolic rewiring of colorectal cancer cells expressing the oncogenic KRASG13D mutation
Charitou, Theodosia, Srihari, Sriganesh, Lynn, Miriam A., Jarboui, Mohamed-Ali, Fasterius, Erik, Moldovan, Max, Shirasawa, Senji, Tsunoda, Toshiyuki, Ueffing, Marius, Xie, Jianling, Xin, Jin, Wang, Xuemin, Proud, Christopher G., Boldt, Karsten, Al-Khalili Szigyarto, Cristina, Kolch, Walter, Lynn, David J.
Published in British journal of cancer (28.05.2019)
Published in British journal of cancer (28.05.2019)
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Journal Article
A new perspective on lipid research in age-related macular degeneration
van Leeuwen, Elisabeth M., Emri, Eszter, Merle, Benedicte M.J., Colijn, Johanna M., Kersten, Eveline, Cougnard-Gregoire, Audrey, Dammeier, Sascha, Meester-Smoor, Magda, Pool, Frances M., de Jong, Eiko K., Delcourt, Cécile, Rodrigez-Bocanegra, Eduardo, Biarnés, Marc, Luthert, Philip J., Ueffing, Marius, Klaver, Caroline C.W., Nogoceke, Everson, den Hollander, Anneke I., Lengyel, Imre
Published in Progress in retinal and eye research (01.11.2018)
Published in Progress in retinal and eye research (01.11.2018)
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Journal Article
Sustained Extracellular Electrical Stimulation Modulates the Permeability of Gap Junctions in rd1 Mouse Retina with Photoreceptor Degeneration
Stürmer, Sophie, Bolz, Sylvia, Zrenner, Eberhart, Ueffing, Marius, Haq, Wadood
Published in International journal of molecular sciences (01.02.2024)
Published in International journal of molecular sciences (01.02.2024)
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Journal Article
Antagonistic activities of CDC14B and CDK1 on USP9X regulate WT1-dependent mitotic transcription and survival
Dietachmayr, Michael, Rathakrishnan, Abirami, Karpiuk, Oleksandra, von Zweydorf, Felix, Engleitner, Thomas, Fernández-Sáiz, Vanesa, Schenk, Petra, Ueffing, Marius, Rad, Roland, Eilers, Martin, Gloeckner, Christian Johannes, Clemm von Hohenberg, Katharina, Bassermann, Florian
Published in Nature communications (09.03.2020)
Published in Nature communications (09.03.2020)
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Journal Article
The small GTPase RAB28 is required for phagocytosis of cone outer segments by the murine retinal pigmented epithelium
Ying, Guoxin, Boldt, Karsten, Ueffing, Marius, Gerstner, Cecilia D., Frederick, Jeanne M., Baehr, Wolfgang
Published in The Journal of biological chemistry (09.11.2018)
Published in The Journal of biological chemistry (09.11.2018)
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Journal Article
Structural model of the dimeric Parkinson’s protein LRRK2 reveals a compact architecture involving distant interdomain contacts
Guaitoli, Giambattista, Raimondi, Francesco, Gilsbach, Bernd K., Gómez-Llorente, Yacob, Deyaert, Egon, Renzi, Fabiana, Li, Xianting, Schaffner, Adam, Jagtap, Pravin Kumar Ankush, Boldt, Karsten, von Zweydorf, Felix, Gotthardt, Katja, Lorimer, Donald D., Yue, Zhenyu, Burgin, Alex, Janjic, Nebojsa, Sattler, Michael, Versées, Wim, Ueffing, Marius, Ubarretxena-Belandia, Iban, Kortholt, Arjan, Gloeckner, Christian Johannes
Published in Proceedings of the National Academy of Sciences - PNAS (26.07.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (26.07.2016)
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Identification of a common non-apoptotic cell death mechanism in hereditary retinal degeneration
Arango-Gonzalez, Blanca, Trifunović, Dragana, Sahaboglu, Ayse, Kranz, Katharina, Michalakis, Stylianos, Farinelli, Pietro, Koch, Susanne, Koch, Fred, Cottet, Sandra, Janssen-Bienhold, Ulrike, Dedek, Karin, Biel, Martin, Zrenner, Eberhart, Euler, Thomas, Ekström, Per, Ueffing, Marius, Paquet-Durand, François
Published in PloS one (13.11.2014)
Published in PloS one (13.11.2014)
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Journal Article
Rods progressively escape saturation to drive visual responses in daylight conditions
Tikidji-Hamburyan, Alexandra, Reinhard, Katja, Storchi, Riccardo, Dietter, Johannes, Seitter, Hartwig, Davis, Katherine E., Idrees, Saad, Mutter, Marion, Walmsley, Lauren, Bedford, Robert A., Ueffing, Marius, Ala-Laurila, Petri, Brown, Timothy M., Lucas, Robert J., Münch, Thomas A.
Published in Nature communications (27.11.2017)
Published in Nature communications (27.11.2017)
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Journal Article
CiliaCarta: An integrated and validated compendium of ciliary genes
van Dam, Teunis J P, Kennedy, Julie, van der Lee, Robin, de Vrieze, Erik, Wunderlich, Kirsten A, Rix, Suzanne, Dougherty, Gerard W, Lambacher, Nils J, Li, Chunmei, Jensen, Victor L, Leroux, Michel R, Hjeij, Rim, Horn, Nicola, Texier, Yves, Wissinger, Yasmin, van Reeuwijk, Jeroen, Wheway, Gabrielle, Knapp, Barbara, Scheel, Jan F, Franco, Brunella, Mans, Dorus A, van Wijk, Erwin, Képès, François, Slaats, Gisela G, Toedt, Grischa, Kremer, Hannie, Omran, Heymut, Szymanska, Katarzyna, Koutroumpas, Konstantinos, Ueffing, Marius, Nguyen, Thanh-Minh T, Letteboer, Stef J F, Oud, Machteld M, van Beersum, Sylvia E C, Schmidts, Miriam, Beales, Philip L, Lu, Qianhao, Giles, Rachel H, Szklarczyk, Radek, Russell, Robert B, Gibson, Toby J, Johnson, Colin A, Blacque, Oliver E, Wolfrum, Uwe, Boldt, Karsten, Roepman, Ronald, Hernandez-Hernandez, Victor, Huynen, Martijn A
Published in PloS one (16.05.2019)
Published in PloS one (16.05.2019)
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Journal Article
HDAC inhibition ameliorates cone survival in retinitis pigmentosa mice
Samardzija, Marijana, Corna, Andrea, Gomez-Sintes, Raquel, Jarboui, Mohamed Ali, Armento, Angela, Roger, Jerome E., Petridou, Eleni, Haq, Wadood, Paquet-Durand, Francois, Zrenner, Eberhart, de la Villa, Pedro, Zeck, Günther, Grimm, Christian, Boya, Patricia, Ueffing, Marius, Trifunović, Dragana
Published in Cell death and differentiation (01.04.2021)
Published in Cell death and differentiation (01.04.2021)
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Journal Article
Characterizing the morbid genome of ciliopathies
Shaheen, Ranad, Szymanska, Katarzyna, Basu, Basudha, Patel, Nisha, Ewida, Nour, Faqeih, Eissa, Al Hashem, Amal, Derar, Nada, Alsharif, Hadeel, Aldahmesh, Mohammed A, Alazami, Anas M, Hashem, Mais, Ibrahim, Niema, Abdulwahab, Firdous M, Sonbul, Rawda, Alkuraya, Hisham, Alnemer, Maha, Al Tala, Saeed, Al-Husain, Muneera, Morsy, Heba, Seidahmed, Mohammed Zain, Meriki, Neama, Al-Owain, Mohammed, AlShahwan, Saad, Tabarki, Brahim, Salih, Mustafa A, Faquih, Tariq, El-Kalioby, Mohamed, Ueffing, Marius, Boldt, Karsten, Logan, Clare V, Parry, David A, Al Tassan, Nada, Monies, Dorota, Megarbane, Andre, Abouelhoda, Mohamed, Halees, Anason, Johnson, Colin A, Alkuraya, Fowzan S
Published in Genome Biology (28.11.2016)
Published in Genome Biology (28.11.2016)
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