Nanobodies to study protein conformational states
Uchański, Tomasz, Pardon, Els, Steyaert, Jan
Published in Current opinion in structural biology (01.02.2020)
Published in Current opinion in structural biology (01.02.2020)
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GABA A receptor signalling mechanisms revealed by structural pharmacology
Masiulis, Simonas, Desai, Rooma, Uchański, Tomasz, Serna Martin, Itziar, Laverty, Duncan, Karia, Dimple, Malinauskas, Tomas, Zivanov, Jasenko, Pardon, Els, Kotecha, Abhay, Steyaert, Jan, Miller, Keith W, Aricescu, A Radu
Published in Nature (London) (24.01.2019)
Published in Nature (London) (24.01.2019)
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Megabodies expand the nanobody toolkit for protein structure determination by single-particle cryo-EM
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Published in Nature methods (01.01.2021)
Published in Nature methods (01.01.2021)
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Single-particle cryo-EM at atomic resolution
Nakane, Takanori, Kotecha, Abhay, Sente, Andrija, McMullan, Greg, Masiulis, Simonas, Brown, Patricia M. G. E., Grigoras, Ioana T., Malinauskaite, Lina, Malinauskas, Tomas, Miehling, Jonas, Uchański, Tomasz, Yu, Lingbo, Karia, Dimple, Pechnikova, Evgeniya V., de Jong, Erwin, Keizer, Jeroen, Bischoff, Maarten, McCormack, Jamie, Tiemeijer, Peter, Hardwick, Steven W., Chirgadze, Dimitri Y., Murshudov, Garib, Aricescu, A. Radu, Scheres, Sjors H. W.
Published in Nature (London) (05.11.2020)
Published in Nature (London) (05.11.2020)
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Conformational transitions and ligand-binding to a muscle-type nicotinic acetylcholine receptor
Zarkadas, Eleftherios, Pebay-Peyroula, Eva, Thompson, Mackenzie John, Schoehn, Guy, Uchański, Tomasz, Steyaert, Jan, Chipot, Christophe, Dehez, Francois, Baenziger, John Edward, Nury, Hugues
Published in Neuron (Cambridge, Mass.) (20.04.2022)
Published in Neuron (Cambridge, Mass.) (20.04.2022)
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Cryo-EM structure of the human α1β3γ2 GABAA receptor in a lipid bilayer
Laverty, Duncan, Desai, Rooma, Uchański, Tomasz, Masiulis, Simonas, Stec, Wojciech J., Malinauskas, Tomas, Zivanov, Jasenko, Pardon, Els, Steyaert, Jan, Miller, Keith W., Aricescu, A. Radu
Published in Nature (London) (24.01.2019)
Published in Nature (London) (24.01.2019)
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An improved yeast surface display platform for the screening of nanobody immune libraries
Uchański, Tomasz, Zögg, Thomas, Yin, Jie, Yuan, Daopeng, Wohlkönig, Alexandre, Fischer, Baptiste, Rosenbaum, Daniel M., Kobilka, Brian K., Pardon, Els, Steyaert, Jan
Published in Scientific reports (23.01.2019)
Published in Scientific reports (23.01.2019)
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Systematic reassessment of chemokine‐receptor pairings confirms CCL20 but not CXCL13 and extends the spectrum of ACKR4 agonists to CCL22
Meyrath, Max, Reynders, Nathan, Uchański, Tomasz, Chevigné, Andy, Szpakowska, Martyna
Published in Journal of leukocyte biology (01.02.2021)
Published in Journal of leukocyte biology (01.02.2021)
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Allosteric nanobodies to study the interactions between SOS1 and RAS
Fischer, Baptiste, Uchański, Tomasz, Sheryazdanova, Aidana, Gonzalez, Simon, Volkov, Alexander N., Brosens, Elke, Zögg, Thomas, Kalichuk, Valentina, Ballet, Steven, Versées, Wim, Sablina, Anna A., Pardon, Els, Wohlkönig, Alexandre, Steyaert, Jan
Published in Nature communications (23.07.2024)
Published in Nature communications (23.07.2024)
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Rapid Discovery and Characterization of Synthetic Neutralizing Antibodies against Anthrax Edema Toxin
Farcasanu, Mara, Wang, Andrew G, Uchański, Tomasz, Bailey, Lucas J, Yue, Jiping, Chen, Zhaochun, Wu, Xiaoyang, Kossiakoff, Anthony, Tang, Wei-Jen
Published in Biochemistry (Easton) (09.07.2019)
Published in Biochemistry (Easton) (09.07.2019)
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The Extended N-Terminal Domain Confers Atypical Chemokine Receptor Properties to CXCR3-B
D'Uonnolo, Giulia, Reynders, Nathan, Meyrath, Max, Abboud, Dayana, Uchański, Tomasz, Laeremans, Toon, Volkman, Brian F, Janji, Bassam, Hanson, Julien, Szpakowska, Martyna, Chevigné, Andy
Published in Frontiers in immunology (01.06.2022)
Published in Frontiers in immunology (01.06.2022)
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CXCL10 Is an Agonist of the CC Family Chemokine Scavenger Receptor ACKR2/D6
Chevigné, Andy, Janji, Bassam, Meyrath, Max, Reynders, Nathan, D'Uonnolo, Giulia, Uchański, Tomasz, Xiao, Malina, Berchem, Guy, Ollert, Markus, Kwon, Yong-Jun, Noman, Muhammad Zaeem, Szpakowska, Martyna
Published in Cancers (02.03.2021)
Published in Cancers (02.03.2021)
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Nanoluciferase-based methods to monitor activation, modulation and trafficking of atypical chemokine receptors
Luís, Rafael, D'Uonnolo, Giulia, Palmer, Christie B, Meyrath, Max, Uchański, Tomasz, Wantz, May, Rogister, Bernard, Janji, Bassam, Chevigné, Andy, Szpakowska, Martyna
Published in Methods in cell biology (2022)
Published in Methods in cell biology (2022)
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GABAA receptor signalling mechanisms revealed by structural pharmacology
Masiulis, Simonas, Desai, Rooma, Uchański, Tomasz, Serna Martin, Itziar, Laverty, Duncan, Karia, Dimple, Malinauskas, Tomas, Zivanov, Jasenko, Pardon, Els, Kotecha, Abhay, Steyaert, Jan, Miller, Keith W., Aricescu, A. Radu
Published in Nature (London) (24.01.2019)
Published in Nature (London) (24.01.2019)
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Journal Article
Conformational transitions and ligand-binding to a muscle-type nicotinic acetylcholine receptor
Baenziger, John E., Zarkadas, Eleftherios, Pebay-Peyroula, Eva, Thompson, Mackenzie, Schoehn, Guy, Uchański, Tomasz, Steyaert, Jan, Chipot, Christophe J., Dehez, Francois, Nury, Hugues
Published in Biophysical journal (11.02.2022)
Published in Biophysical journal (11.02.2022)
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Cryo-EM structure of the human α1β3γ2 GABA^sub A^ receptor in a lipid bilayer
Laverty, Duncan, Desai, Rooma, Uchański, Tomasz, Masiulis, Simonas, Stec, Wojciech J, Malinauskas, Tomas, Zivanov, Jasenko, Pardon, Els, Steyaert, Jan, Miller, Keith W, Aricescu, A Radu
Published in Nature (London) (24.01.2019)
Published in Nature (London) (24.01.2019)
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Author Correction: GABAA receptor signalling mechanisms revealed by structural pharmacology
Masiulis, Simonas, Desai, Rooma, Uchański, Tomasz, Martin, Itziar Serna, Laverty, Duncan, Karia, Dimple, Malinauskas, Tomas, Zivanov, Jasenko, Pardon, Els, Kotecha, Abhay, Steyaert, Jan, Miller, Keith W., Aricescu, A. Radu
Published in Nature (London) (21.02.2019)
Published in Nature (London) (21.02.2019)
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Journal Article
GABA^sub A^ receptor signalling mechanisms revealed by structural pharmacology
Masiulis, Simonas, Desai, Rooma, Uchański, Tomasz, Martin, Itziar Serna, Laverty, Duncan, Karia, Dimple, Malinauskas, Tomas, Zivanov, Jasenko, Pardon, Els, Kotecha, Abhay, Steyaert, Jan, Miller, Keith W, Aricescu, A Radu
Published in Nature (London) (24.01.2019)
Published in Nature (London) (24.01.2019)
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