Notch Signaling Regulates Mitochondrial Metabolism and NF-κB Activity in Triple-Negative Breast Cancer Cells via IKKα-Dependent Non-canonical Pathways
Hossain, Fokhrul, Sorrentino, Claudia, Ucar, Deniz A, Peng, Yin, Matossian, Margarite, Wyczechowska, Dorota, Crabtree, Judy, Zabaleta, Jovanny, Morello, Silvana, Del Valle, Luis, Burow, Matthew, Collins-Burow, Bridgette, Pannuti, Antonio, Minter, Lisa M, Golde, Todd E, Osborne, Barbara A, Miele, Lucio
Published in Frontiers in oncology (04.12.2018)
Published in Frontiers in oncology (04.12.2018)
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Journal Article
Notch Signaling in Myeloid Cells as a Regulator of Tumor Immune Responses
Hossain, Fokhrul, Majumder, Samarpan, Ucar, Deniz A, Rodriguez, Paulo C, Golde, Todd E, Minter, Lisa M, Osborne, Barbara A, Miele, Lucio
Published in Frontiers in immunology (04.06.2018)
Published in Frontiers in immunology (04.06.2018)
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Journal Article
Evaluation of deacetylase inhibition in metaplastic breast carcinoma using multiple derivations of preclinical models of a new patient-derived tumor
Chang, Tiffany C, Matossian, Margarite D, Elliott, Steven, Burks, Hope E, Sabol, Rachel A, Ucar, Deniz A, Wathieu, Henri, Zabaleta, Jovanny, Del Valle, Luis, Gill, Sukhmani, Martin, Elizabeth, Riker, Adam I, Miele, Lucio, Bunnell, Bruce A, Burow, Matthew E, Collins-Burow, Bridgette M
Published in PloS one (09.10.2020)
Published in PloS one (09.10.2020)
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Journal Article
Sulindac sulfide as a non-immune suppressive γ-secretase modulator to target triple-negative breast cancer
Hossain, Fokhrul, Ucar, Deniz A, Monticone, Giulia, Ran, Yong, Majumder, Samarpan, Larter, Kristina, Luu, Hanh, Wyczechowska, Dorota, Heidari, Soroor, Xu, Keli, Shanthalingam, Sudarvili, Matossian, Margarite, Xi, Yaguang, Burow, Matthew, Collins-Burow, Bridgette, Del Valle, Luis, Hicks, Chindo, Zabaleta, Jovanny, Golde, Todd, Osborne, Barbara, Miele, Lucio
Published in Frontiers in immunology (13.10.2023)
Published in Frontiers in immunology (13.10.2023)
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Journal Article
Correction: Evaluation of deacetylase inhibition in metaplastic breast carcinoma using multiple derivations of preclinical models of a new patient-derived tumor
Chang, Tiffany C, Matossian, Margarite D, Elliott, Steven, Burks, Hope E, Sabol, Rachel A, Ucar, Deniz A, Wathieu, Henri, Zabaleta, Jovanny, Valle, Luis Del, Gill, Sukhmani, Martin, Elizabeth, Riker, Adam I, Miele, Lucio, Bunnell, Bruce A, Burow, Matthew E, Collins-Burow, Bridgette M
Published in PloS one (29.04.2021)
Published in PloS one (29.04.2021)
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Journal Article
Targeting the Cbl-b-Notch1 axis as a novel immunotherapeutic strategy to boost CD8+ T-cell responses
Monticone, Giulia, Huang, Zhi, Csibi, Fred, Leit, Silvana, Ciccone, David, Champhekar, Ameya S, Austin, Jermaine E, Ucar, Deniz A, Hossain, Fokhrul, Ibba, Salome V, Boulares, A Hamid, Carpino, Nicholas, Xu, Keli, Majumder, Samarpan, Osborne, Barbara A, Loh, Christine, Miele, Lucio
Published in Frontiers in immunology (26.08.2022)
Published in Frontiers in immunology (26.08.2022)
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Journal Article
Molecular Mechanisms of Epithelial to Mesenchymal Transition Regulated by ERK5 Signaling
Bhatt, Akshita B, Patel, Saloni, Matossian, Margarite D, Ucar, Deniz A, Miele, Lucio, Burow, Matthew E, Flaherty, Patrick T, Cavanaugh, Jane E
Published in Biomolecules (Basel, Switzerland) (29.01.2021)
Published in Biomolecules (Basel, Switzerland) (29.01.2021)
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Journal Article
Diverse and converging roles of ERK1/2 and ERK5 pathways on mesenchymal to epithelial transition in breast cancer
Bhatt, Akshita B., Wright, Thomas D., Barnes, Van, Chakrabarty, Suravi, Matossian, Margarite D., Lexner, Erin, Ucar, Deniz A., Miele, Lucio, Flaherty, Patrick T., Burow, Matthew E., Cavanaugh, Jane E.
Published in Translational oncology (01.06.2021)
Published in Translational oncology (01.06.2021)
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Journal Article
Inhibiting the interaction of cMET and IGF-1R with FAK effectively reduces growth of pancreatic cancer cells in vitro and in vivo
Ucar, Deniz A, Magis, Andrew T, He, Di-Hua, Lawrence, Nicholas J, Sebti, Said M, Kurenova, Elena, Zajac-Kaye, Maria, Zhang, Jianliang, Hochwald, Steven N
Published in Anti-cancer agents in medicinal chemistry (01.05.2013)
Published in Anti-cancer agents in medicinal chemistry (01.05.2013)
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Journal Article
Disruption of the protein interaction between FAK and IGF-1R inhibits melanoma tumor growth
Ucar, Deniz A., Kurenova, Elena, Garrett, Timothy J., Cance, William G., Nyberg, Carl, Cox, Audrey, Massoll, Nicole, Ostrov, David A., Lawrence, Nicholas, Sebti, Saïd M., Zajac-Kaye, Maria, Hochwald, Steven N.
Published in Cell cycle (Georgetown, Tex.) (01.09.2012)
Published in Cell cycle (Georgetown, Tex.) (01.09.2012)
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Journal Article
ERK5 Is Required for Tumor Growth and Maintenance Through Regulation of the Extracellular Matrix in Triple Negative Breast Cancer
Hoang, Van T, Matossian, Margarite D, Ucar, Deniz A, Elliott, Steven, La, Jacqueline, Wright, Maryl K, Burks, Hope E, Perles, Aaron, Hossain, Fokhrul, King, Connor T, Browning, Valentino E, Bursavich, Jacob, Fang, Fang, Del Valle, Luis, Bhatt, Akshita B, Cavanaugh, Jane E, Flaherty, Patrick T, Anbalagan, Muralidharan, Rowan, Brian G, Bratton, Melyssa R, Nephew, Kenneth P, Miele, Lucio, Collins-Burow, Bridgette M, Martin, Elizabeth C, Burow, Matthew E
Published in Frontiers in oncology (03.08.2020)
Published in Frontiers in oncology (03.08.2020)
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Journal Article
FAK and interacting proteins as therapeutic targets in pancreatic cancer
Ucar, Deniz A, Hochwald, Steven N
Published in Anti-cancer agents in medicinal chemistry (01.12.2010)
Published in Anti-cancer agents in medicinal chemistry (01.12.2010)
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Journal Article
A novel small molecule inhibitor of FAK and IGF-1R protein interactions decreases growth of human esophageal carcinoma
Ucar, Deniz A, Cox, Audrey, He, Di-Hua, Ostrov, David A, Kurenova, Elena, Hochwald, Steven N
Published in Anti-cancer agents in medicinal chemistry (01.09.2011)
Published in Anti-cancer agents in medicinal chemistry (01.09.2011)
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Journal Article
Dual inhibition of MEK1/2 and MEK5 suppresses the EMT/migration axis in triple‐negative breast cancer through FRA‐1 regulation
Hoang, Van T., Matossian, Margarite D., La, Jacqueline, Hoang, Kristine, Ucar, Deniz A., Elliott, Steven, Burks, Hope E., Wright, Thomas D., Patel, Saloni, Bhatt, Akshita, Phamduy, Theresa, Chrisey, Douglas, Buechlein, Aaron, Rusch, Douglas B., Nephew, Kenneth P., Anbalagan, Murali, Rowan, Brian, Cavanaugh, Jane E., Flaherty, Patrick T., Miele, Lucio, Collins‐Burow, Bridgette M., Burow, Matthew E.
Published in Journal of cellular biochemistry (01.08.2021)
Published in Journal of cellular biochemistry (01.08.2021)
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Journal Article
A novel screening approach comparing kinase activity of small molecule inhibitors with similar molecular structures and distinct biologic effects in triple-negative breast cancer to identify targetable signaling pathways
Matossian, Margarite D, Burks, Hope E, Elliott, Steven, Hoang, Van T, Zuercher, William J, Wells, Carrow, Drewry, David H, Kapadia, Nirav, Chang, Tiffany, Yan, Thomas, Windsor, Gabrielle O, Nguyen, Khoa, Fang, Fang, Nephew, Kenneth P, Buechlein, Aaron, Rusch, Douglas B, Sabol, Rachel A, Ucar, Deniz A, Zabaleta, Jovanny, Miele, Lucio, Bunnell, Bruce A, Collins-Burow, Bridgette M, Burow, Matthew E
Published in Anti-cancer drugs (01.09.2020)
Published in Anti-cancer drugs (01.09.2020)
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Journal Article
Use of retinoic acid/aldehyde dehydrogenase pathway as potential targeted therapy against cancer stem cells
Moreb, Jan S., Ucar-Bilyeu, Deniz A., Khan, Abdullah
Published in Cancer Chemotherapy and Pharmacology (01.02.2017)
Published in Cancer Chemotherapy and Pharmacology (01.02.2017)
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Journal Article
Book Review
Focal adhesion kinase signaling and function in pancreatic cancer
Ucar, Deniz A, Dang, Long H, Hochwald, Steven N
Published in Frontiers in bioscience (Elite edition) (01.01.2011)
Published in Frontiers in bioscience (Elite edition) (01.01.2011)
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