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Published in Molecular cancer therapeutics (01.01.2020)
Published in Molecular cancer therapeutics (01.01.2020)
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Use of the novel Plk1 inhibitor ZK-thiazolidinone to elucidate functions of Plk1 in early and late stages of mitosis
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Published in Molecular biology of the cell (01.10.2007)
Published in Molecular biology of the cell (01.10.2007)
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Damage Incorporated: Discovery of the Potent, Highly Selective, Orally Available ATR Inhibitor BAY 1895344 with Favorable Pharmacokinetic Properties and Promising Efficacy in Monotherapy and in Combination Treatments in Preclinical Tumor Models
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Published in Journal of medicinal chemistry (09.07.2020)
Published in Journal of medicinal chemistry (09.07.2020)
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Discovery of IRAK4 Inhibitors BAY1834845 (Zabedosertib) and BAY1830839
Bothe, Ulrich, Günther, Judith, Nubbemeyer, Reinhard, Siebeneicher, Holger, Ring, Sven, Bömer, Ulf, Peters, Michaele, Rausch, Alexandra, Denner, Karsten, Himmel, Herbert, Sutter, Andreas, Terebesi, Ildiko, Lange, Martin, Wengner, Antje M., Guimond, Nicolas, Thaler, Tobias, Platzek, Johannes, Eberspächer, Uwe, Schäfer, Martina, Steuber, Holger, Zollner, Thomas M., Steinmeyer, Andreas, Schmidt, Nicole
Published in Journal of medicinal chemistry (25.01.2024)
Published in Journal of medicinal chemistry (25.01.2024)
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BAY-8400: A Novel Potent and Selective DNA-PK Inhibitor which Shows Synergistic Efficacy in Combination with Targeted Alpha Therapies
Berger, Markus, Wortmann, Lars, Buchgraber, Philipp, Lücking, Ulrich, Zitzmann-Kolbe, Sabine, Wengner, Antje M, Bader, Benjamin, Bömer, Ulf, Briem, Hans, Eis, Knut, Rehwinkel, Hartmut, Bartels, Florian, Moosmayer, Dieter, Eberspächer, Uwe, Lienau, Philip, Hammer, Stefanie, Schatz, Christoph A, Wang, Qiuwen, Wang, Qi, Mumberg, Dominik, Nising, Carl F, Siemeister, Gerhard
Published in Journal of medicinal chemistry (09.09.2021)
Published in Journal of medicinal chemistry (09.09.2021)
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Identification of Small Molecules that Modulate Mutant p53 Condensation
Lemos, Clara, Schulze, Luise, Weiske, Joerg, Meyer, Hanna, Braeuer, Nico, Barak, Naomi, Eberspächer, Uwe, Werbeck, Nicolas, Stresemann, Carlo, Lange, Martin, Lesche, Ralf, Zablowsky, Nina, Juenemann, Katrin, Kamburov, Atanas, Luh, Laura Martina, Leissing, Thomas Markus, Mortier, Jeremie, Steckel, Michael, Steuber, Holger, Eis, Knut, Eheim, Ashley, Steigemann, Patrick
Published in iScience (25.09.2020)
Published in iScience (25.09.2020)
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Structural Evidence for Isoform-Selective Allosteric Inhibition of Lactate Dehydrogenase A
Friberg, Anders, Rehwinkel, Hartmut, Nguyen, Duy, Pütter, Vera, Quanz, Maria, Weiske, Jörg, Eberspächer, Uwe, Heisler, Iring, Langer, Gernot
Published in ACS omega (09.06.2020)
Published in ACS omega (09.06.2020)
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Affinity Map of Bromodomain Protein 4 (BRD4) Interactions with the Histone H4 Tail and the Small Molecule Inhibitor JQ1
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Published in The Journal of biological chemistry (28.03.2014)
Published in The Journal of biological chemistry (28.03.2014)
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2-(MORPHOLIN-4-YL)-L,7-NAPHTHYRIDINES
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Year of Publication 13.09.2022
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Year of Publication 13.09.2022
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2-(MORPHOLIN-4-YL)-1,7-NAPHTHYRIDINES
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Year of Publication 31.01.2022
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Year of Publication 31.01.2022
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4H-PYRROLO[3,2-C]PYRIDIN-4-ONE DERIVATIVES
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Year of Publication 02.05.2019
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Year of Publication 02.05.2019
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2-(morpholin-4-yl)-l,7-naphthyridines
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Year of Publication 14.03.2019
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Year of Publication 14.03.2019
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2-(MORPHOLIN-4-YL)-1,7-NAPHTHYRIDINES
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Year of Publication 31.08.2018
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Year of Publication 31.08.2018
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2-(MORPHOLIN-4-YL)-1,7-NAPHTHYRIDINES
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Year of Publication 10.07.2017
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Year of Publication 10.07.2017
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2-(MORPHOLIN-4-YL)-1,7-NAPHTHYRIDINES
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Year of Publication 11.02.2016
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Year of Publication 11.02.2016
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Year of Publication 01.08.2020
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Year of Publication 01.08.2020
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2-(MORPHOLIN-4-YL)-1,7-NAPHTHYRIDINES
BADER BENJAMIN, LIENAU PHILIP, MOOSMAYER DIETER, KOPPITZ MARCUS, VON NUSSBAUM FRANZ, SIEMEISTER GERHARD, EBERSPACHER UWE, EIS KNUT, WORTMANN LARS, LUCKING ULRICH, BONE WILHELM, WENGNER ANTJE MARGRET, GRUDZINSKA-GOEBEL JOANNA, LEFRANC JULIEN, BRIEM HANS, SCHICK HANS
Year of Publication 20.09.2019
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Year of Publication 20.09.2019
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2-(morpholin-4-yl)-l,7-naphthyridines
BADER BENJAMIN, LIENAU PHILIP, MOOSMAYER DIETER, KOPPITZ MARCUS, VON NUSSBAUM FRANZ, SIEMEISTER GERHARD, EBERSPACHER UWE, EIS KNUT, WORTMANN LARS, LUCKING ULRICH, BONE WILHELM, WENGNER ANTJE MARGRET, GRUDZINSKA-GOEBEL JOANNA, LEFRANC JULIEN, BRIEM HANS, SCHICK HANS
Year of Publication 06.09.2019
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Year of Publication 06.09.2019
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