Population pharmacokinetics of the GIP/GLP receptor agonist tirzepatide
Schneck, Karen, Urva, Shweta
Published in CPT: pharmacometrics and systems pharmacology (01.03.2024)
Published in CPT: pharmacometrics and systems pharmacology (01.03.2024)
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Journal Article
LY3437943, a novel triple glucagon, GIP, and GLP-1 receptor agonist for glycemic control and weight loss: From discovery to clinical proof of concept
Coskun, Tamer, Urva, Shweta, Roell, William C., Qu, Hongchang, Loghin, Corina, Moyers, Julie S., O’Farrell, Libbey S., Briere, Daniel A., Sloop, Kyle W., Thomas, Melissa K., Pirro, Valentina, Wainscott, David B., Willard, Francis S., Abernathy, Matthew, Morford, LaRonda, Du, Yu, Benson, Charles, Gimeno, Ruth E., Haupt, Axel, Milicevic, Zvonko
Published in Cell metabolism (06.09.2022)
Published in Cell metabolism (06.09.2022)
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LY3298176, a novel dual GIP and GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus: From discovery to clinical proof of concept
Coskun, Tamer, Sloop, Kyle W., Loghin, Corina, Alsina-Fernandez, Jorge, Urva, Shweta, Bokvist, Krister B., Cui, Xuewei, Briere, Daniel A., Cabrera, Over, Roell, William C., Kuchibhotla, Uma, Moyers, Julie S., Benson, Charles T., Gimeno, Ruth E., D'Alessio, David A., Haupt, Axel
Published in Molecular metabolism (Germany) (01.12.2018)
Published in Molecular metabolism (Germany) (01.12.2018)
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Journal Article
The novel dual glucose‐dependent insulinotropic polypeptide and glucagon‐like peptide‐1 (GLP‐1) receptor agonist tirzepatide transiently delays gastric emptying similarly to selective long‐acting GLP‐1 receptor agonists
Urva, Shweta, Coskun, Tamer, Loghin, Corina, Cui, Xuewei, Beebe, Emily, O'Farrell, Libbey, Briere, Daniel A., Benson, Charles, Nauck, Michael A., Haupt, Axel
Published in Diabetes, obesity & metabolism (01.10.2020)
Published in Diabetes, obesity & metabolism (01.10.2020)
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Journal Article
Physiologically based pharmacokinetic model for T84.66: A monoclonal anti-CEA antibody
Urva, Shweta R., Yang, Victor C., Balthasar, Joseph P.
Published in Journal of pharmaceutical sciences (01.03.2010)
Published in Journal of pharmaceutical sciences (01.03.2010)
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Journal Article
Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonist
Willard, Francis S, Douros, Jonathan D, Gabe, Maria Bn, Showalter, Aaron D, Wainscott, David B, Suter, Todd M, Capozzi, Megan E, van der Velden, Wijnand Jc, Stutsman, Cynthia, Cardona, Guemalli R, Urva, Shweta, Emmerson, Paul J, Holst, Jens J, D'Alessio, David A, Coghlan, Matthew P, Rosenkilde, Mette M, Campbell, Jonathan E, Sloop, Kyle W
Published in JCI insight (03.09.2020)
Published in JCI insight (03.09.2020)
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Journal Article
Sensitive high performance liquid chromatographic assay for assessment of doxorubicin pharmacokinetics in mouse plasma and tissues
Urva, Shweta R., Shin, Beom Soo, Yang, Victor C., Balthasar, Joseph P.
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15.03.2009)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15.03.2009)
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Journal Article
Characterization of LY2775240, a selective phosphodiesterase‐4 inhibitor, in nonclinical models and in healthy subjects
Patel, Dipak R., Urva, Shweta, Ho, Stephen, Buckman, Cody J., Ma, Yanfei, Lim, Jean, Sissons, Sean E., Zuniga, Mary S., Philips, Diane, Cox, Karen, Dairaghi, Daniel J.
Published in Clinical and translational science (01.05.2021)
Published in Clinical and translational science (01.05.2021)
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Effects of Hepatic Impairment on the Pharmacokinetics of Everolimus: A Single-Dose, Open-Label, Parallel-Group Study
Peveling-Oberhag, Jan, MD, Zeuzem, Stefan, MD, Yong, Wei Peng, MD, Kunz, Tiffany, BS, Paquet, Thierry, MS, Bouillaud, Emmanuel, MS, Urva, Shweta, PhD, Anak, Oezlem, MD, Sellami, Dalila, MD, Kobalava, Zhanna, MD, PhD
Published in Clinical therapeutics (01.03.2013)
Published in Clinical therapeutics (01.03.2013)
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Feasibility of adding everolimus to carboplatin and paclitaxel, with or without bevacizumab, for treatment-naive, advanced non–small cell lung cancer
Eberhardt, Wilfried E. E., Mitchell, Paul, Schiller, Joan H., Brown, Michael P., Thomas, Michael, Mills, Glenn, Jehl, Valentine, Urva, Shweta R., De Leo, Jeffrey J., Gogov, Sven, Papadimitrakopoulou, Vassiliki
Published in Investigational new drugs (01.02.2014)
Published in Investigational new drugs (01.02.2014)
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Journal Article
AN ELISA FOR QUANTIFICATION OF T84.66, A MONOCLONAL ANTI-CEA ANTIBODY, IN MOUSE PLASMA
Urva, Shweta R., Yang, Victor C., Balthasar, Joseph P.
Published in Journal of immunoassay & immunochemistry (01.01.2010)
Published in Journal of immunoassay & immunochemistry (01.01.2010)
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Journal Article
Muvalaplin, an Oral Small Molecule Inhibitor of Lipoprotein(a) Formation: A Randomized Clinical Trial
Nicholls, Stephen J, Nissen, Steven E, Fleming, Cynthia, Urva, Shweta, Suico, Jeffrey, Berg, Paul H, Linnebjerg, Helle, Ruotolo, Giacomo, Turner, P. Kellie, Michael, Laura F
Published in JAMA : the journal of the American Medical Association (19.09.2023)
Published in JAMA : the journal of the American Medical Association (19.09.2023)
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Journal Article
Efficacy and safety of LY3298176, a novel dual GIP and GLP-1 receptor agonist, in patients with type 2 diabetes: a randomised, placebo-controlled and active comparator-controlled phase 2 trial
Frias, Juan Pablo, Nauck, Michael A, Van, Joanna, Kutner, Mark E, Cui, Xuewei, Benson, Charles, Urva, Shweta, Gimeno, Ruth E, Milicevic, Zvonko, Robins, Deborah, Haupt, Axel
Published in The Lancet (British edition) (17.11.2018)
Published in The Lancet (British edition) (17.11.2018)
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Journal Article
Efficacy and tolerability of tirzepatide, a dual glucose‐dependent insulinotropic peptide and glucagon‐like peptide‐1 receptor agonist in patients with type 2 diabetes: A 12‐week, randomized, double‐blind, placebo‐controlled study to evaluate different dose‐escalation regimens
Frias, Juan Pablo, Nauck, Michael A., Van, Joanna, Benson, Charles, Bray, Ross, Cui, Xuewei, Milicevic, Zvonko, Urva, Shweta, Haupt, Axel, Robins, Deborah A.
Published in Diabetes, obesity & metabolism (01.06.2020)
Published in Diabetes, obesity & metabolism (01.06.2020)
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Journal Article