Telomerase-specific oncolytic immunotherapy for promoting efficacy of PD-1 blockade in osteosarcoma
Mochizuki, Yusuke, Tazawa, Hiroshi, Demiya, Koji, Kure, Miho, Kondo, Hiroya, Komatsubara, Tadashi, Sugiu, Kazuhisa, Hasei, Joe, Yoshida, Aki, Kunisada, Toshiyuki, Urata, Yasuo, Kagawa, Shunsuke, Ozaki, Toshifumi, Fujiwara, Toshiyoshi
Published in Cancer Immunology, Immunotherapy (01.05.2021)
Published in Cancer Immunology, Immunotherapy (01.05.2021)
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p53-armed oncolytic adenovirus induces autophagy and apoptosis in KRAS and BRAF-mutant colorectal cancer cells
Tamura, Shuta, Tazawa, Hiroshi, Hori, Naoto, Li, Yuncheng, Yamada, Motohiko, Kikuchi, Satoru, Kuroda, Shinji, Urata, Yasuo, Kagawa, Shunsuke, Fujiwara, Toshiyoshi
Published in PloS one (16.11.2023)
Published in PloS one (16.11.2023)
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Clinical impact of high-quality testing for peritoneal lavage cytology in pancreatic cancer
Tanemura, Masahiro, Furukawa, Kenta, Mikamori, Manabu, Asaoka, Tadafumi, Yasuoka, Hironao, Marukawa, Daiki, Urata, Yasuo, Yamada, Daisaku, Kobayashi, Shogo, Eguchi, Hidetoshi
Published in Scientific reports (03.05.2024)
Published in Scientific reports (03.05.2024)
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Phase Ia dose escalation study of OBP-801, a cyclic depsipeptide class I histone deacetylase inhibitor, in patients with advanced solid tumors
Heath, Elisabeth I., Weise, Amy, Vaishampayan, Ulka, Danforth, Dailan, Ungerleider, Richard S., Urata, Yasuo
Published in Investigational new drugs (01.04.2022)
Published in Investigational new drugs (01.04.2022)
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Pluripotent epigenetic regulator OBP-801 maintains filtering blebs in glaucoma filtration surgery model
Yamamoto, Yuji, Mukai, Atsushi, Ikushima, Toru, Urata, Yasuo, Kinoshita, Shigeru, Hamuro, Junji, Ueno, Morio, Sotozono, Chie
Published in Scientific reports (01.12.2020)
Published in Scientific reports (01.12.2020)
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Fluorescence-guided assessment of bone and soft-tissue sarcomas for predicting the efficacy of telomerase-specific oncolytic adenovirus
Uotani, Koji, Tazawa, Hiroshi, Hasei, Joe, Fujiwara, Tomohiro, Yoshida, Aki, Yamakawa, Yasuaki, Omori, Toshinori, Sugiu, Kazuhisa, Komatsubara, Tadashi, Kondo, Hiroya, Morita, Takuya, Kiyono, Masahiro, Yokoo, Suguru, Hata, Toshiaki, Kunisada, Toshiyuki, Takeda, Ken, Urata, Yasuo, Fujiwara, Toshiyoshi, Ozaki, Toshifumi
Published in PloS one (20.02.2024)
Published in PloS one (20.02.2024)
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A Flow Cytometry-Based Method to Determine the Titer of Adenoviruses Expressing an Extraneous Gene
Asada, Akikazu, Hayakawa, Hideki, Yanase, Natsuki, Abe, Kanae, Sakurai, Fuminori, Mizuguchi, Hiroyuki, Urata, Yasuo
Published in Biological & pharmaceutical bulletin (01.10.2018)
Published in Biological & pharmaceutical bulletin (01.10.2018)
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Journal Article
In vivo internal tumor illumination by telomerase-dependent adenoviral GFP for precise surgical navigation
Kishimoto, Hiroyuki, Zhao, Ming, Hayashi, Katsuhiro, Urata, Yasuo, Tanaka, Noriaki, Fujiwara, Toshiyoshi, Penman, Sheldon, Hoffman, Robert M
Published in Proceedings of the National Academy of Sciences - PNAS (25.08.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (25.08.2009)
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A Phase I Study of Telomerase-specific Replication Competent Oncolytic Adenovirus (Telomelysin) for Various Solid Tumors
Nemunaitis, John, Tong, Alex W, Nemunaitis, Michael, Senzer, Neil, Phadke, Anagha P, Bedell, Cynthia, Adams, Ned, Zhang, Yu-An, Maples, Phillip B, Chen, Salina, Pappen, Beena, Burke, James, Ichimaru, Daiju, Urata, Yasuo, Fujiwara, Toshiyoshi
Published in Molecular therapy (01.02.2010)
Published in Molecular therapy (01.02.2010)
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Journal Article
Detection of circulating tumor cells in cervical cancer using a conditionally replicative adenovirus targeting telomerase‐positive cells
Takakura, Masahiro, Matsumoto, Takeo, Nakamura, Mitsuhiro, Mizumoto, Yasunari, Myojyo, Subaru, Yamazaki, Rena, Iwadare, Jyunpei, Bono, Yukiko, Orisaka, Shunsuke, Obata, Takeshi, Iizuka, Takashi, Kagami, Kyosuke, Nakayama, Kentaro, Hayakawa, Hideki, Sakurai, Fuminori, Mizuguchi, Hiroyuki, Urata, Yasuo, Fujiwara, Toshiyoshi, Kyo, Satoru, Sasagawa, Toshiyuki, Fujiwara, Hiroshi
Published in Cancer science (01.01.2018)
Published in Cancer science (01.01.2018)
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Oncolytic virotherapy promotes radiosensitivity in soft tissue sarcoma by suppressing anti-apoptotic MCL1 expression
Omori, Toshinori, Tazawa, Hiroshi, Yamakawa, Yasuaki, Osaki, Shuhei, Hasei, Joe, Sugiu, Kazuhisa, Komatsubara, Tadashi, Fujiwara, Tomohiro, Yoshida, Aki, Kunisada, Toshiyuki, Urata, Yasuo, Kagawa, Shunsuke, Ozaki, Toshifumi, Fujiwara, Toshiyoshi
Published in PloS one (22.04.2021)
Published in PloS one (22.04.2021)
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Overexpression of Adenovirus E1A Reverses Transforming Growth Factor-β-induced Epithelial-mesenchymal Transition in Human Esophageal Cancer Cells
Masuda, Tomoya, Tazawa, Hiroshi, Hashimoto, Yuuri, Ieda, Takeshi, Kikuchi, Satoru, Kuroda, Shinji, Noma, Kazuhiro, Urata, Yasuo, Kagawa, Shunsuke, Fujiwara, Toshiyoshi
Published in Acta medica Okayama (01.04.2022)
Published in Acta medica Okayama (01.04.2022)
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Ablation of MCL1 expression by virally induced microRNA-29 reverses chemoresistance in human osteosarcomas
Osaki, Shuhei, Tazawa, Hiroshi, Hasei, Joe, Yamakawa, Yasuaki, Omori, Toshinori, Sugiu, Kazuhisa, Komatsubara, Tadashi, Fujiwara, Tomohiro, Sasaki, Tsuyoshi, Kunisada, Toshiyuki, Yoshida, Aki, Urata, Yasuo, Kagawa, Shunsuke, Ozaki, Toshifumi, Fujiwara, Toshiyoshi
Published in Scientific reports (30.06.2016)
Published in Scientific reports (30.06.2016)
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Journal Article
Oncolytic virus-mediated p53 overexpression promotes immunogenic cell death and efficacy of PD-1 blockade in pancreatic cancer
Araki, Hiroyuki, Tazawa, Hiroshi, Kanaya, Nobuhiko, Kajiwara, Yoshinori, Yamada, Motohiko, Hashimoto, Masashi, Kikuchi, Satoru, Kuroda, Shinji, Yoshida, Ryuichi, Umeda, Yuzo, Urata, Yasuo, Kagawa, Shunsuke, Fujiwara, Toshiyoshi
Published in Molecular therapy. Oncolytics (15.12.2022)
Published in Molecular therapy. Oncolytics (15.12.2022)
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Improved Resection and Outcome of Colon-Cancer Liver Metastasis with Fluorescence-Guided Surgery Using In Situ GFP Labeling with a Telomerase-Dependent Adenovirus in an Orthotopic Mouse Model
Yano, Shuya, Takehara, Kiyoto, Miwa, Shinji, Kishimoto, Hiroyuki, Hiroshima, Yukihiko, Murakami, Takashi, Urata, Yasuo, Kagawa, Shunsuke, Bouvet, Michael, Fujiwara, Toshiyoshi, Hoffman, Robert M
Published in PloS one (05.02.2016)
Published in PloS one (05.02.2016)
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Oncolytic virotherapy reverses chemoresistance in osteosarcoma by suppressing MDR1 expression
Sugiu, Kazuhisa, Tazawa, Hiroshi, Hasei, Joe, Yamakawa, Yasuaki, Omori, Toshinori, Komatsubara, Tadashi, Mochizuki, Yusuke, Kondo, Hiroya, Osaki, Shuhei, Fujiwara, Tomohiro, Yoshida, Aki, Kunisada, Toshiyuki, Ueda, Koji, Urata, Yasuo, Kagawa, Shunsuke, Ozaki, Toshifumi, Fujiwara, Toshiyoshi
Published in Cancer chemotherapy and pharmacology (01.09.2021)
Published in Cancer chemotherapy and pharmacology (01.09.2021)
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Role of zoledronic acid in oncolytic virotherapy: Promotion of antitumor effect and prevention of bone destruction
Yamakawa, Yasuaki, Tazawa, Hiroshi, Hasei, Joe, Osaki, Shuhei, Omori, Toshinori, Sugiu, Kazuhisa, Komatsubara, Tadashi, Uotani, Kouji, Fujiwara, Tomohiro, Yoshida, Aki, Kunisada, Toshiyuki, Urata, Yasuo, Kagawa, Shunsuke, Ozaki, Toshifumi, Fujiwara, Toshiyoshi
Published in Cancer science (01.09.2017)
Published in Cancer science (01.09.2017)
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Impact of endoscopic stent insertion on detection of viable circulating tumor cells from obstructive colorectal cancer
Yamashita, Shinya, Tanemura, Masahiro, Sawada, Genta, Moon, Jeongho, Shimizu, Yosuke, Yamaguchi, Toshiki, Kuwai, Toshio, Urata, Yasuo, Kuraoka, Kazuya, Hatanaka, Nobutaka, Yamashita, Yoshinori, Taniyama, Kiyomi
Published in Oncology letters (01.01.2018)
Published in Oncology letters (01.01.2018)
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Tumor-selective, adenoviral-mediated GFP genetic labeling of human cancer in the live mouse reports future recurrence after resection
Kishimoto, Hiroyuki, Aki, Ryoichi, Urata, Yasuo, Bouvet, Michael, Momiyama, Masashi, Tanaka, Noriaki, Fujiwara, Toshiyoshi, Hoffman, Robert M.
Published in Cell cycle (Georgetown, Tex.) (15.08.2011)
Published in Cell cycle (Georgetown, Tex.) (15.08.2011)
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Sensitive detection of viable circulating tumor cells using a novel conditionally telomerase-selective replicating adenovirus in non-small cell lung cancer patients
Togo, Shinsaku, Katagiri, Nobuyoshi, Namba, Yukiko, Tulafu, Miniwan, Nagahama, Kumi, Kadoya, Kotarou, Takamochi, Kazuya, Oh, Siaki, Suzuki, Kenji, Sakurai, Fuminori, Mizuguchi, Hiroyuki, Urata, Yasuo, Takahashi, Kazuhisa
Published in Oncotarget (23.05.2017)
Published in Oncotarget (23.05.2017)
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