COVID-19 cynomolgus macaque model reflecting human COVID-19 pathological conditions
Urano, Emiko, Okamura, Tomotaka, Ono, Chikako, Ueno, Shiori, Nagata, Satoshi, Kamada, Haruhiko, Higuchi, Mahoko, Furukawa, Mugi, Kamitani, Wataru, Matsuura, Yoshiharu, Kawaoka, Yoshihiro, Yasutomi, Yasuhiro
Published in Proceedings of the National Academy of Sciences - PNAS (26.10.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (26.10.2021)
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Journal Article
Repeated Intravaginal Inoculation of Zika Virus Protects Cynomolgus Monkeys from Subcutaneous Superchallenge
Shofa, Maya, Okamura, Tomotaka, Urano, Emiko, Matsuura, Yoshiharu, Yasutomi, Yasuhiro, Saito, Akatsuki
Published in International journal of molecular sciences (13.11.2022)
Published in International journal of molecular sciences (13.11.2022)
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Journal Article
Quenching protein dynamics interferes with HIV capsid maturation
Wang, Mingzhang, Quinn, Caitlin M, Perilla, Juan R, Zhang, Huilan, Shirra, Jr, Randall, Hou, Guangjin, Byeon, In-Ja, Suiter, Christopher L, Ablan, Sherimay, Urano, Emiko, Nitz, Theodore J, Aiken, Christopher, Freed, Eric O, Zhang, Peijun, Schulten, Klaus, Gronenborn, Angela M, Polenova, Tatyana
Published in Nature communications (24.11.2017)
Published in Nature communications (24.11.2017)
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Journal Article
Resistance to Second-Generation HIV-1 Maturation Inhibitors
Urano, Emiko, Timilsina, Uddhav, Kaplan, Justin A, Ablan, Sherimay, Ghimire, Dibya, Pham, Phuong, Kuruppu, Nishani, Mandt, Rebecca, Durell, Stewart R, Nitz, Theodore J, Martin, David E, Wild, Carl T, Gaur, Ritu, Freed, Eric O
Published in Journal of virology (15.03.2019)
Published in Journal of virology (15.03.2019)
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Journal Article
Intestinal microbe-dependent ω3 lipid metabolite αKetoA prevents inflammatory diseases in mice and cynomolgus macaques
Nagatake, Takahiro, Kishino, Shigenobu, Urano, Emiko, Murakami, Haruka, Kitamura, Nahoko, Konishi, Kana, Ohno, Harumi, Tiwari, Prabha, Morimoto, Sakiko, Node, Eri, Adachi, Jun, Abe, Yuichi, Isoyama, Junko, Sawane, Kento, Honda, Tetsuya, Inoue, Asuka, Uwamizu, Akiharu, Matsuzaka, Takashi, Miyamoto, Yoichi, Hirata, So-Ichiro, Saika, Azusa, Shibata, Yuki, Hosomi, Koji, Matsunaga, Ayu, Shimano, Hitoshi, Arita, Makoto, Aoki, Junken, Oka, Masahiro, Matsutani, Akira, Tomonaga, Takeshi, Kabashima, Kenji, Miyachi, Motohiko, Yasutomi, Yasuhiro, Ogawa, Jun, Kunisawa, Jun
Published in Mucosal immunology (01.02.2022)
Published in Mucosal immunology (01.02.2022)
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Journal Article
Therapeutic potential of HIV protease-activable CASP3
Miyauchi, Kosuke, Urano, Emiko, Takizawa, Mari, Ichikawa, Reiko, Komano, Jun
Published in Scientific reports (11.04.2012)
Published in Scientific reports (11.04.2012)
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Journal Article
A Synthetic C34 Trimer of HIV-1 gp41 Shows Significant Increase in Inhibition Potency
Nomura, Wataru, Hashimoto, Chie, Ohya, Aki, Miyauchi, Kosuke, Urano, Emiko, Tanaka, Tomohiro, Narumi, Tetsuo, Nakahara, Toru, Komano, Jun A., Yamamoto, Naoki, Tamamura, Hirokazu
Published in ChemMedChem (06.02.2012)
Published in ChemMedChem (06.02.2012)
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Journal Article
Structural Modulation Study of Inhibitory Compounds for Ribonuclease H Activity of Human Immunodeficiency Virus Type 1 Reverse Transcriptase
Yanagita, Hiroshi, Fudo, Satoshi, Urano, Emiko, Ichikawa, Reiko, Ogata, Masakazu, Yokota, Mizuho, Murakami, Tsutomu, Wu, Honggui, Chiba, Joe, Komano, Jun, Hoshino, Tyuji
Published in Chemical & pharmaceutical bulletin (2012)
Published in Chemical & pharmaceutical bulletin (2012)
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Structural and biochemical study on the inhibitory activity of derivatives of 5-nitro-furan-2-carboxylic acid for RNase H function of HIV-1 reverse transcriptase
Yanagita, Hiroshi, Urano, Emiko, Matsumoto, Kishow, Ichikawa, Reiko, Takaesu, Yoshihisa, Ogata, Masakazu, Murakami, Tsutomu, Wu, Hongui, Chiba, Joe, Komano, Jun, Hoshino, Tyuji
Published in Bioorganic & medicinal chemistry (15.01.2011)
Published in Bioorganic & medicinal chemistry (15.01.2011)
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Toll-like receptor (TLR) 3 as a surrogate sensor of retroviral infection in human cells
Miyauchi, Kosuke, Urano, Emiko, Takeda, Satoshi, Murakami, Tsutomu, Okada, Yoshiaki, Cheng, Kui, Yin, Hang, Kubo, Masato, Komano, Jun
Published in Biochemical and biophysical research communications (03.08.2012)
Published in Biochemical and biophysical research communications (03.08.2012)
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Journal Article
The hematopoietic cell-specific Rho GTPase inhibitor ARHGDIB/D4GDI limits HIV type 1 replication
Watanabe, Tadashi, Urano, Emiko, Miyauchi, Kosuke, Ichikawa, Reiko, Hamatake, Makiko, Misawa, Naoko, Sato, Kei, Ebina, Hirotaka, Koyanagi, Yoshio, Komano, Jun
Published in AIDS research and human retroviruses (01.08.2012)
Published in AIDS research and human retroviruses (01.08.2012)
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Journal Article
Evaluation of a synthetic C34 trimer of HIV-1 gp41 as AIDS vaccines
Hashimoto, Chie, Nomura, Wataru, Ohya, Aki, Urano, Emiko, Miyauchi, Kosuke, Narumi, Tetsuo, Aikawa, Haruo, Komano, Jun A., Yamamoto, Naoki, Tamamura, Hirokazu
Published in Bioorganic & medicinal chemistry (15.05.2012)
Published in Bioorganic & medicinal chemistry (15.05.2012)
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Journal Article
Novel Postentry Inhibitor of Human Immunodeficiency Virus Type 1 Replication Screened by Yeast Membrane-Associated Two-Hybrid System
Urano, Emiko, Kuramochi, Noriko, Ichikawa, Reiko, Murayama, Somay Yamagata, Miyauchi, Kosuke, Tomoda, Hiroshi, Takebe, Yutaka, Nermut, Milan, Komano, Jun, Morikawa, Yuko
Published in Antimicrobial Agents and Chemotherapy (01.09.2011)
Published in Antimicrobial Agents and Chemotherapy (01.09.2011)
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Journal Article
Separate elements are required for ligand‐dependent and ‐independent internalization of metastatic potentiator CXCR4
Futahashi, Yuko, Komano, Jun, Urano, Emiko, Aoki, Toru, Hamatake, Makiko, Miyauchi, Kosuke, Yoshida, Takeshi, Koyanagi, Yoshio, Matsuda, Zene, Yamamoto, Naoki
Published in Cancer science (01.03.2007)
Published in Cancer science (01.03.2007)
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Dominant‐negative derivative of EBNA1 represses EBNA1‐mediated transforming gene expression during the acute phase of Epstein–Barr virus infection independent of rapid loss of viral genome
Kariya, Yumi, Hamatake, Makiko, Urano, Emiko, Yoshiyama, Hironori, Shimizu, Norio, Komano, Jun
Published in Cancer science (01.04.2010)
Published in Cancer science (01.04.2010)
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Regulation of the susceptibility of HIV-1 to a neutralizing antibody KD-247 by nonepitope mutations distant from its epitope
TAKIZAWA, Mari, MIYAUCHI, Kosuke, URANO, Emiko, KUSAGAWA, Shigeru, KITAMURA, Katsuhiko, NAGANAWA, Satoshi, MURAKAMI, Toshio, HONDA, Mitsuo, YAMAMOTO, Naoki, KOMANO, Jun
Published in AIDS (London) (28.11.2011)
Published in AIDS (London) (28.11.2011)
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Journal Article
Peptidic HIV integrase inhibitors derived from HIV gene products: Structure–activity relationship studies
Suzuki, Shintaro, Maddali, Kasthuraiah, Hashimoto, Chie, Urano, Emiko, Ohashi, Nami, Tanaka, Tomohiro, Ozaki, Taro, Arai, Hiroshi, Tsutsumi, Hiroshi, Narumi, Tetsuo, Nomura, Wataru, Yamamoto, Naoki, Pommier, Yves, Komano, Jun A., Tamamura, Hirokazu
Published in Bioorganic & medicinal chemistry (15.09.2010)
Published in Bioorganic & medicinal chemistry (15.09.2010)
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Journal Article
Identification of the P-TEFb complex-interacting domain of Brd4 as an inhibitor of HIV-1 replication by functional cDNA library screening in MT-4 cells
Urano, Emiko, Kariya, Yumi, Futahashi, Yuko, Ichikawa, Reiko, Hamatake, Makiko, Fukazawa, Hidesuke, Morikawa, Yuko, Yoshida, Takeshi, Koyanagi, Yoshio, Yamamoto, Naoki, Komano, Jun
Published in FEBS letters (10.12.2008)
Published in FEBS letters (10.12.2008)
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