Molecular and Pharmacological Properties of a Potent and Selective Novel Nonsteroidal Progesterone Receptor Agonist Tanaproget
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Structure-Based Design of Estrogen Receptor-β Selective Ligands
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Synthesis and Structure−Activity Relationship of Novel 6-Aryl-1,4- dihydrobenzo[d][1,3]oxazine-2-thiones as Progesterone Receptor Modulators Leading to the Potent and Selective Nonsteroidal Progesterone Receptor Agonist Tanaproget
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Published in Journal of medicinal chemistry (11.08.2005)
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Estrogen receptor ligands: design and synthesis of new 2-arylindene-1-ones
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Published in Bioorganic & medicinal chemistry letters (15.06.2005)
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A new generation of progesterone receptor modulators
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Design, Synthesis, and Preclinical Characterization of Novel, Highly Selective Indole Estrogens
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Published in Journal of medicinal chemistry (24.05.2001)
Published in Journal of medicinal chemistry (24.05.2001)
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Novel pyrrole-containing progesterone receptor modulators
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Published in Bioorganic & medicinal chemistry letters (03.05.2004)
Published in Bioorganic & medicinal chemistry letters (03.05.2004)
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7-Substituted 2-phenyl-benzofurans as ERβ selective ligands
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Optimization of 3-(1H-Indazol-3-ylmethyl)-1,5-benzodiazepines as Potent, Orally Active CCK-A Agonists
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Published in Journal of medicinal chemistry (15.08.1997)
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STRUCTURE-ACTIVITY-RELATIONSHIPS FOR INHIBITION OF TYPE-1 AND TYPE-2 HUMAN 5-ALPHA-REDUCTASE AND HUMAN ADRENAL 3-BETA-HYDROXY-DELTA(5)-STEROID DEHYDROGENASE 3-KETO-DELTA(5)-STEROID ISOMERASE BY 6-AZAANDROST-4-EN-3-ONES - OPTIMIZATION OF THE C17 SUBSTITUENT
FRYE, SV, HAFFNER, CD, MALONEY, PR, HINER, RN, DORSEY, GF, NOE, RA, UNWALLA, RJ, BATCHELOR, KW, BRAMSON, HN, STUART, JD, SCHWEIKER, SL, VANARNOLD, J, BICKETT, DM, MOSS, ML, TIAN, GC, LEE, FW, TIPPIN, TK, JAMES, MK, GRIZZLE, MK, LONG, JE, CROOM, DK
Published in Journal of medicinal chemistry (07.07.1995)
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6-AZASTEROIDS - STRUCTURE-ACTIVITY-RELATIONSHIPS FOR INHIBITION OF TYPE-1 AND TYPE-2 HUMAN 5-ALPHA-REDUCTASE AND HUMAN ADRENAL 3-BETA-HYDROXY-DELTA(5)-STEROID DEHYDROGENASE 3-KETO-DELTA(5)-STEROID ISOMERASE
FRYE, SV, HAFFNER, CD, MALONEY, PR, MOOK, RA, DORSEY, GF, HINER, RN, CRIBBS, CM, WHEELER, TN, RAY, JA, ANDREWS, RC, BATCHELOR, KW, BRAMSON, HN, STUART, JD, SCHWEIKER, SL, VANARNOLD, J, CROOM, S, BICKETT, DM, MOSS, ML, TIAN, GC, UNWALLA, RJ, LEE, FW, TIPPIN, TK, JAMES, MK, GRIZZLE, MK, LONG, JE, SCHUSTER, SV
Published in Journal of medicinal chemistry (22.07.1994)
Published in Journal of medicinal chemistry (22.07.1994)
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6-AZASTEROIDS - POTENT DUAL INHIBITORS OF HUMAN TYPE-1 AND 2 STEROID 5-ALPHA-REDUCTASE
FRYE, SV, HAFFNER, CD, MALONEY, PR, MOOK, RA, HINER, RN, BATCHELOR, KW, BRAMSON, HN, STUART, JD, SCHWEIKER, SL, VANARNOLD, J, BICKETT, DM, MOSS, ML, TIAN, GC, UNWALLA, RJ, LEE, FW, TIPPIN, TK, JAMES, MK, GRIZZLE, MK, LONG, JE, SCHUSTER, SV, DORSEY, GF
Published in Journal of medicinal chemistry (24.12.1993)
Published in Journal of medicinal chemistry (24.12.1993)
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3-[2-(N-Phenylacetamide)]-1,5-benzodiazepines: Orally Active, Binding Selective CCK-A Agonists
Willson, Timothy M, Henke, Brad R, Momtahen, Tanya M, Myers, Peter L, Sugg, Elizabeth E, Unwalla, Rayomand J, Croom, Dallas K, Dougherty, Robert W, Grizzle, Mary K, Johnson, Michael F, Queen, Kennedy L, Rimele, Thomas J, Yingling, Jeffrey D, James, Michael K
Published in Journal of medicinal chemistry (19.07.1996)
Published in Journal of medicinal chemistry (19.07.1996)
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Structure-activity relationships involving the catechol subunit of rolipram
Stafford, Jeffrey A., Feldman, Paul L., Marron, Brian E., Schoenen, Frank J., Valvano, Nicole L., Unwalla, Rayomand J., Domanico, Paul L., Brawley, E.Sloan, Leesnitzer, Michael A., Rose, Dudley A., Dougherty, Robert W.
Published in Bioorganic & medicinal chemistry letters (11.08.1994)
Published in Bioorganic & medicinal chemistry letters (11.08.1994)
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Phosphodiesterase type IV (PDE IV) inhibition. Synthesis and evaluation of a series of 1,3,4-trisubstituted pyrrolidines
Stafford, Jeffrey A, Valvano, Nicole L, Feldman, Paul L, Sloan Brawley, E, Cowan, David J, Domanico, Paul L, Leesnitzer, Michael A, Rose, Dudley A, Stimpson, Stephen A, Strickland, Alan B, Unwalla, Rayomand J, Verghese, Margrith W
Published in Bioorganic & medicinal chemistry letters (07.09.1995)
Published in Bioorganic & medicinal chemistry letters (07.09.1995)
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Preparation of (.alpha.,.alpha.-dichlorobenzyl)silanes and (.alpha.-halobenzyl)silanes
Larson, Gerald L, Cartledge, Frank K, Nunez, Roberto, Unwalla, Rayomand J, Klesse, Ricardo, Del Valle, Luis
Published in Organometallics (01.02.1992)
Published in Organometallics (01.02.1992)
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Conformational analysis of the cis- and trans-1,2-bis(trimethylsilyl)cyclohexanes (BTMSC): molecular mechanics calculations and nuclear magnetic resonance spectroscopy. A preferred diaxial conformation for the trans-isomer
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Published in Journal of the Chemical Society, Perkin Transactions 2 (1997)
Published in Journal of the Chemical Society, Perkin Transactions 2 (1997)
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