Search Results - "UNANGST, PAUL C" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Design and synthesis of hepatoselective, pyrrole-based HMG-CoA reductase inhibitors

Design and synthesis of hepatoselective, pyrrole-based HMG-CoA reductase inhibitors

by Pfefferkorn, Jeffrey A., Song, Yuntao, Sun, Kuai-Lin, Miller, Steven R., Trivedi, Bharat K., Choi, Chulho, Sorenson, Roderick J., Bratton, Larry D., Unangst, Paul C., Larsen, Scott D., Poel, Toni-Jo, Cheng, Xue-Min, Lee, Chitase, Erasga, Noe, Auerbach, Bruce, Askew, Valerie, Dillon, Lisa, Hanselman, Jeffrey C., Lin, Zhiwu, Lu, Gina, Robertson, Andrew, Olsen, Karl, Mertz, Thomas, Sekerke, Catherine, Pavlovsky, Alexander, Harris, Melissa S., Bainbridge, Graeme, Caspers, Nicole, Chen, Huifen, Eberstadt, Matthias
Published in Bioorganic & medicinal chemistry letters (15.08.2007)

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Journal Article

Synthesis, Structure−Activity Relationships, and in Vivo Evaluations of Substituted Di-tert-butylphenols as a Novel Class of Potent, Selective, and Orally Active Cyclooxygenase-2 Inhibitors. 1. Thiazolone and Oxazolone Series

Synthesis, Structure−Activity Relationships, and in Vivo Evaluations of Substituted Di-tert-butylphenols as a Novel Class of Potent, Selective, and Orally Active Cyclooxygenase-2 Inhibitors. 1. Thiazolone and Oxazolone Series

by Song, Yuntao, Connor, David T, Doubleday, Robert, Sorenson, Roderick J, Sercel, Anthony D, Unangst, Paul C, Roth, Bruce D, Gilbertsen, Richard B, Chan, Kam, Schrier, Denis J, Guglietta, Antonio, Bornemeier, Dirk A, Dyer, Richard D
Published in Journal of medicinal chemistry (08.04.1999)

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Novel 1,2,4-oxadiazoles and 1,2,4-thiadiazoles as dual 5-lipoxygenase and cyclooxygenase inhibitors

Novel 1,2,4-oxadiazoles and 1,2,4-thiadiazoles as dual 5-lipoxygenase and cyclooxygenase inhibitors

by Unangst, Paul C, Shrum, Gary P, Connor, David T, Dyer, Richard D, Schrier, Denis J
Published in Journal of medicinal chemistry (01.10.1992)

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Discovery of pyrrole-based hepatoselective ligands as potent inhibitors of HMG-CoA reductase

Discovery of pyrrole-based hepatoselective ligands as potent inhibitors of HMG-CoA reductase

by Bratton, Larry D., Auerbach, Bruce, Choi, Chulho, Dillon, Lisa, Hanselman, Jeffrey C., Larsen, Scott D., Lu, Gina, Olsen, Karl, Pfefferkorn, Jeffrey A., Robertson, Andrew, Sekerke, Catherine, Trivedi, Bharat K., Unangst, Paul C.
Published in Bioorganic & medicinal chemistry (15.08.2007)

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Synthesis and SAR of selective benzothiophene, benzofuran, and indole-based peroxisome proliferator-activated receptor δ agonists

Synthesis and SAR of selective benzothiophene, benzofuran, and indole-based peroxisome proliferator-activated receptor δ agonists

by Filzen, Gary F., Bratton, Larry, Cheng, Xue-Min, Erasga, Noe, Geyer, Andrew, Lee, Chitase, Lu, Gina, Pulaski, Jim, Sorenson, Roderick J., Unangst, Paul C., Trivedi, B.K., Xu, Xiangyang
Published in Bioorganic & medicinal chemistry letters (01.07.2007)

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Novel benzothiophene-, benzofuran-, and naphthalenecarboxamidotetrazoles as potential antiallergy agents

Novel benzothiophene-, benzofuran-, and naphthalenecarboxamidotetrazoles as potential antiallergy agents

by Connor, David T, Cetenko, Wiaczeslaw A, Mullican, Michael D, Sorenson, Roderick J, Unangst, Paul C, Weikert, Robert J, Adolphson, Richard L, Kennedy, John A, Thueson, David O
Published in Journal of medicinal chemistry (01.03.1992)

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Journal Article

Synthesis, Structure−Activity Relationships, and in Vivo Evaluations of Substituted Di-tert-butylphenols as a Novel Class of Potent, Selective, and Orally Active Cyclooxygenase-2 Inhibitors. 2. 1,3,4- and 1,2,4-Thiadiazole Series

Synthesis, Structure−Activity Relationships, and in Vivo Evaluations of Substituted Di-tert-butylphenols as a Novel Class of Potent, Selective, and Orally Active Cyclooxygenase-2 Inhibitors. 2. 1,3,4- and 1,2,4-Thiadiazole Series

by Song, Yuntao, Connor, David T, Sercel, Anthony D, Sorenson, Roderick J, Doubleday, Robert, Unangst, Paul C, Roth, Bruce D, Beylin, Vlad G, Gilbertsen, Richard B, Chan, Kam, Schrier, Denis J, Guglietta, Antonio, Bornemeier, Dirk A, Dyer, Richard D
Published in Journal of medicinal chemistry (08.04.1999)

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Discovery of highly potent and selective benzyloxybenzyl-based peroxisome proliferator-activator receptor (PPAR) δ agonists

Discovery of highly potent and selective benzyloxybenzyl-based peroxisome proliferator-activator receptor (PPAR) δ agonists

by Bratton, Larry D., Filzen, Gary F., Geyer, Andrew, Hoffman, Jennifer K., Lu, Gina, Pulaski, Jim, Trivedi, Bharat K., Unangst, Paul C., Xu, Xiangyang
Published in Bioorganic & medicinal chemistry letters (01.07.2007)

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Synthesis and biological evaluation of 5-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]oxazoles, -thiazoles, and -imidazoles: novel dual 5-lipoxygenase and cyclooxygenase inhibitors with antiinflammatory activity

Synthesis and biological evaluation of 5-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]oxazoles, -thiazoles, and -imidazoles: novel dual 5-lipoxygenase and cyclooxygenase inhibitors with antiinflammatory activity

by Unangst, Paul C, Connor, David T, Cetenko, Wiaczeslaw A, Sorenson, Roderick J, Kostlan, Catherine R, Sircar, Jagadish C, Wright, Clifford D, Schrier, Denis J, Dyer, Richard D
Published in Journal of medicinal chemistry (01.01.1994)

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Chromeno[3,4-c]pyridin-5-ones: Selective Human Dopamine D4 Receptor Antagonists as Potential Antipsychotic Agents

Chromeno[3,4-c]pyridin-5-ones: Selective Human Dopamine D4 Receptor Antagonists as Potential Antipsychotic Agents

by Unangst, Paul C, Capiris, Thomas, Connor, David T, Heffner, Thomas G, MacKenzie, Robert G, Miller, Steven R, Pugsley, Thomas A, Wise, Lawrence D
Published in Journal of medicinal chemistry (15.08.1997)

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Novel indolecarboxamidotetrazoles as potential antiallergy agents

Novel indolecarboxamidotetrazoles as potential antiallergy agents

by Unangst, Paul C, Connor, David T, Stabler, S. Russell, Weikert, Robert J, Carethers, Mary E, Kennedy, John A, Thueson, David O, Chestnut, James C, Adolphson, Richard L, Conroy, M. C
Published in Journal of medicinal chemistry (01.06.1989)

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(Aryloxy)alkylamines as Selective Human Dopamine D4 Receptor Antagonists: Potential Antipsychotic Agents

(Aryloxy)alkylamines as Selective Human Dopamine D4 Receptor Antagonists: Potential Antipsychotic Agents

by Unangst, Paul C, Capiris, Thomas, Connor, David T, Doubleday, Robert, Heffner, Thomas G, MacKenzie, Robert G, Miller, Steven R, Pugsley, Thomas A, Wise, Lawrence D
Published in Journal of medicinal chemistry (05.12.1997)

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Journal Article

PROCESS FOR PREPARING ANITALLERGIC 4H-FURO (3,2-B) INDOLES

PROCESS FOR PREPARING ANITALLERGIC 4H-FURO (3,2-B) INDOLES

by UNANGST PAUL C
Year of Publication 11.05.1987

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Patent

Acidic furo[3,2-b]indoles. A new series of potent antiallergy agents

Acidic furo[3,2-b]indoles. A new series of potent antiallergy agents

by Unangst, Paul C, Carethers, Mary E, Webster, Kenneth, Janik, Grace M, Robichaud, Lillian J
Published in Journal of medicinal chemistry (01.12.1984)

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Journal Article

ACIDIC INDOLE COMPOUNDS AND PROCESS FOR PREPARING THEREOF

ACIDIC INDOLE COMPOUNDS AND PROCESS FOR PREPARING THEREOF

by UNANGST, PAUL C, STABLER, S RUSSELL, CONNER, DAVID T
Year of Publication 13.03.1989

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Patent

3,5-DI-TERTIARY-BUTYL-4-HYDROXYPHENYL-1,3,4-THIADIAZOLES, AND OXADIAZOLES AND 3,5-DI-TERTIARY-BUTYL-4-HYDROXYPHENYL-1,2,4-THIADIAZOLES, OXADIAZOLES AND TRIAZOLES AS ANTIINFLAMMATORY AGENTS

3,5-DI-TERTIARY-BUTYL-4-HYDROXYPHENYL-1,3,4-THIADIAZOLES, AND OXADIAZOLES AND 3,5-DI-TERTIARY-BUTYL-4-HYDROXYPHENYL-1,2,4-THIADIAZOLES, OXADIAZOLES AND TRIAZOLES AS ANTIINFLAMMATORY AGENTS

by FLYNN, DANIEL L, UNANGST, PAUL C, KOSTLAN, CATHERINE R, CONNER, DAVID T, MULLICAN, MICHAEL W, SHRUM, GARY P
Year of Publication 08.04.1997

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Patent

PROCESS FOR PREPARING 3-(2-MONO-AND DIALKYLAMINO)PROPYL)-)1,2,3,4-TETRAHYDRO-5H-(1)BENZOPYRANO(3,4-C)PYRIDINE-5-ONES

PROCESS FOR PREPARING 3-(2-MONO-AND DIALKYLAMINO)PROPYL)-)1,2,3,4-TETRAHYDRO-5H-(1)BENZOPYRANO(3,4-C)PYRIDINE-5-ONES

by UNANGST, PAUL C, CONNOR, DAVID T, SCHWENDER, CHARLES F, SORENSON, RODERICK J
Year of Publication 09.03.1989

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Patent

3-(Aminoalkyl)-1,2,3,4-tetrahydro-5H-[1]benzopyrano[3,4-c]pyridin-5-ones as potential anticholinergic bronchodilators

3-(Aminoalkyl)-1,2,3,4-tetrahydro-5H-[1]benzopyrano[3,4-c]pyridin-5-ones as potential anticholinergic bronchodilators

by Connor, David T, Unangst, Paul C, Schwender, Charles F, Sorenson, Roderick J, Carethers, Mary E, Puchalski, Chester, Brown, Richard E, Finkel, Martin P
Published in Journal of medicinal chemistry (01.03.1989)

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Journal Article

Synthesis and antiallergy activity of 4-oxopyrano[3,2-b]indoles

Synthesis and antiallergy activity of 4-oxopyrano[3,2-b]indoles

by Unangst, Paul C, Brown, Richard E, Herzig, David J
Published in Journal of medicinal chemistry (01.11.1980)

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Journal Article

Chromeno[3,4-c]pyridin-5-ones: Selective human dopamine D-4 receptor antagonists as potential antipsychotic agents

Chromeno[3,4-c]pyridin-5-ones: Selective human dopamine D-4 receptor antagonists as potential antipsychotic agents

by Unangst, PC, Capiris, T, Connor, DT, Heffner, TG, MacKenzie, RG, Miller, Pugsley, TA, Wise, LD
Published in Journal of medicinal chemistry (15.08.1997)

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Journal Article

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