Regulation of Retinoidal Actions by Diazepinylbenzoic Acids. Retinoid Synergists Which Activate the RXR−RAR Heterodimers
Umemiya, Hiroki, Fukasawa, Hiroshi, Ebisawa, Masayuki, Eyrolles, Laurence, Kawachi, Emiko, Eisenmann, Ghislaine, Gronemeyer, Hinrich, Hashimoto, Yuichi, Shudo, Koichi, Kagechika, Hiroyuki
Published in Journal of medicinal chemistry (19.12.1997)
Published in Journal of medicinal chemistry (19.12.1997)
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Journal Article
Retinoid X Receptor-Antagonistic Diazepinylbenzoic Acids
EBISAWA, Masayuki, UMEMIYA, Hiroki, OHTA, Kiminori, FUKASAWA, Hiroshi, KAWACHI, Emiko, CHRISTOFFEL, Ghislaine, GRONEMEYER, Hinrich, TSUJI, Motonori, HASHIMOTO, Yuichi, SHUDO, Koichi, KAGECHIKA, Hiroyuki
Published in Chemical & pharmaceutical bulletin (01.12.1999)
Published in Chemical & pharmaceutical bulletin (01.12.1999)
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Journal Article
Action Mechanism of Retinoid-Synergistic Dibenzodiazepines
Umemiya, Hiroki, Kagechika, Hiroyuki, Fukasawa, Hiroshi, Kawachi, Emiko, Ebisawa, Masayuki, Hashimoto, Yuichi, Eisenmann, Ghislaine, Erb, Cathie, Pornon, Astrid, Chambon, Pierre, Gronemeyer, Hinrich, Shudo, Koichi
Published in Biochemical and biophysical research communications (07.04.1997)
Published in Biochemical and biophysical research communications (07.04.1997)
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Journal Article
Inhibition of IL-1-Induced IL-6 Production by Synthetic Retinoids
Kagechika, Hiroyuki, Kawachi, Emiko, Fukasawa, Hiroshi, Saito, Go, Iwanami, Naoko, Umemiya, Hiroki, Hashimoto, Yuichi, Shudo, Koichi
Published in Biochemical and biophysical research communications (13.02.1997)
Published in Biochemical and biophysical research communications (13.02.1997)
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Journal Article
Pyrrole derivatives as potent inhibitors of lymphocyte-specific kinase: Structure, synthesis, and SAR
Takayama, Tetsuo, Umemiya, Hiroki, Amada, Hideaki, Yabuuchi, Tetsuya, Shiozawa, Fumiyasu, Katakai, Hironori, Takaoka, Akiko, Yamaguchi, Akie, Endo, Mayumi, Sato, Masakazu
Published in Bioorganic & medicinal chemistry letters (2010)
Published in Bioorganic & medicinal chemistry letters (2010)
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Journal Article
Ring-fused pyrazole derivatives as potent inhibitors of lymphocyte-specific kinase (Lck): Structure, synthesis, and SAR
Takayama, Tetsuo, Umemiya, Hiroki, Amada, Hideaki, Yabuuchi, Tetsuya, Koami, Takeshi, Shiozawa, Fumiyasu, Oka, Yusuke, Takaoka, Akiko, Yamaguchi, Akie, Endo, Mayumi, Sato, Masakazu
Published in Bioorganic & medicinal chemistry letters (2010)
Published in Bioorganic & medicinal chemistry letters (2010)
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Journal Article
Retinoid Antagonists
UMEMIYA, Hiroki, KAGECHIKA, Hiroyuki, FUKASAWA, Hiroshi, HASHIMOTO, Yuichi, SHUDO, Koichi
Published in YAKUGAKU ZASSHI (01.12.1996)
Published in YAKUGAKU ZASSHI (01.12.1996)
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A mutation mimicking ligand-induced conformational change yields a constitutive RXR that senses allosteric effects in heterodimers
Vivat, Valerie, Zechel, Christina, Wurtz, Jean-Marie, Bourguet, William, Kagechika, Hiroyuki, Umemiya, Hiroki, Shudo, Koichi, Moras, Dino, Gronemeyer, Hinrich, Chambon, Pierre
Published in The EMBO journal (15.09.1997)
Published in The EMBO journal (15.09.1997)
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Journal Article
PYRAZINAMIDE COMPOUND
WATATANI, KENGO, SAITO, NORIKO, UMEMIYA, HIROKI, KAWABE, KENICHI, KAWAGUCHI, TAKANORI, SASAKO, SHIGETADA, OKADA, TAKUMI
Year of Publication 24.12.2008
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Year of Publication 24.12.2008
Patent
Imidazole derivatives as new potent and selective 20-HETE synthase inhibitors
Nakamura, Toshio, Kakinuma, Hiroyuki, Umemiya, Hiroki, Amada, Hideaki, Miyata, Noriyuki, Taniguchi, Kazuo, Bando, Kagumi, Sato, Masakazu
Published in Bioorganic & medicinal chemistry letters (19.01.2004)
Published in Bioorganic & medicinal chemistry letters (19.01.2004)
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Journal Article
PICOLINAMIDE COMPOUND
WATATANI, KENGO, SAITO, NORIKO, UMEMIYA, HIROKI, KAWABE, KENICHI, KAWAGUCHI, TAKANORI, SASAKO, SHIGETADA, WAKASUGI, DAISUKE, OKADA, TAKUMI
Year of Publication 09.10.2008
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Year of Publication 09.10.2008
Patent
HETEROARYLBENZENE COMPOUNDS
BOHNO, MASAHIRO, NAGATSUKA, TAKAYUKI, ITOH, SHIN, UMEMIYA, HIROKI, KAWABE, KENICHI, TAKAHASHI, MASATO, SASAKO, SHIGETADA, SATOU, RUI, SHIMIZU, TAKANORI, SHIROKAWA, SHINICHI
Year of Publication 22.01.2009
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Year of Publication 22.01.2009
Patent
SPIRO-RING COMPOUND
UMEMIYA, HIROKI, SUGA, YOICHIROU, SAITO, SHIUJI, SATO, MASAKAZU, KAWASHIMA, NAOYA
Year of Publication 20.11.2003
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Year of Publication 20.11.2003
Patent
RING-FUSED PYRAZOLE DERIVATIVE
SHIOZAWA, FUMIYASU, AMADA, HIDEAKI, OKA, YUSUKE, UMEMIYA, HIROKI, KOAMI, TAKESHI, SATO, MASAKAZU, YABUUCHI, TETSUYA
Year of Publication 08.03.2007
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Year of Publication 08.03.2007
Patent
HETEROCYCLE DERIVATIVE HAVING 20-HETE-PRODUCING ENZYME INHIBITORY ACTIVITY
UMEMIYA, HIROKI, SATO, MASAKAZU, KAKINUMA, HIROYUKI, NAKAMURA, TOSHIO
Year of Publication 20.03.2003
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Year of Publication 20.03.2003
Patent
PYRAZOLOPYRIMIDINE COMPOUND
OKA, YUSUKE, UMEMIYA, HIROKI, ASANUMA, HAJIME, HAYASHI, KEISHI, YAGI, MAKOTO, NISHIKAWA, RIE, SASAKO, SHIGETADA, SHIMIZU, TAKANORI, OKADA, TAKUMI
Year of Publication 10.07.2008
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Year of Publication 10.07.2008
Patent