Mechanistic investigation of poly(ethylene imine)-based siRNA delivery: Disulfide bonds boost intracellular release of the cargo
Breunig, Miriam, Hozsa, Constantin, Lungwitz, Uta, Watanabe, Kazuo, Umeda, Isao, Kato, Hiroyuki, Goepferich, Achim
Published in Journal of controlled release (25.08.2008)
Published in Journal of controlled release (25.08.2008)
Get full text
Journal Article
In vitro activity of isavuconazole against 140 reference fungal strains and 165 clinically isolated yeasts from Japan
Yamazaki, Toshikazu, Inagaki, Yukiko, Fujii, Toshihiko, Ohwada, Jun, Tsukazaki, Masao, Umeda, Isao, Kobayashi, Kazuko, Shimma, Nobuo, Page, Malcolm G.P, Arisawa, Mikio
Published in International journal of antimicrobial agents (01.10.2010)
Published in International journal of antimicrobial agents (01.10.2010)
Get full text
Journal Article
The design and synthesis of a new tumor-selective fluoropyrimidine carbamate, Capecitabine
SHIMMA, N, UMEDA, I, KURUMA, I, HORII, I, ISHITSUKA, H, ARASAKI, M, MURASAKI, C, MASUBUCHI, K, KOHCHI, Y, MIWA, M, URA, M, SAWADA, N, TAHARA, H
Published in Bioorganic & medicinal chemistry (01.07.2000)
Published in Bioorganic & medicinal chemistry (01.07.2000)
Get full text
Journal Article
Design, synthesis and antifungal activity of a novel water soluble prodrug of antifungal triazole
Ohwada, Jun, Tsukazaki, Masao, Hayase, Tadakatsu, Oikawa, Nobuhiro, Isshiki, Yoshiaki, Fukuda, Hiroshi, Mizuguchi, Eisaku, Sakaitani, Masahiro, Shiratori, Yasuhiko, Yamazaki, Toshikazu, Ichihara, Shigeyasu, Umeda, Isao, Shimma, Nobuo
Published in Bioorganic & medicinal chemistry letters (01.01.2003)
Published in Bioorganic & medicinal chemistry letters (01.01.2003)
Get full text
Journal Article
Comparative Antitumor Activity and Intestinal Toxicity of 5′‐Deoxy‐5‐fluorouridine and Its Prodrug Trimethoxybenzoyl‐5′‐deoxy‐5‐fluorocytidine
Ninomiya, Yasuyuki, Miwa, Masanori, Eda, Hiroyuki, Sahara, Hiroshi, Fujimoto, Kaori, Ishida, Masako, Umeda, Isao, Yokose, Kazuteru, Ishitsuka, Hideo
Published in Cancer science (01.02.1990)
Published in Cancer science (01.02.1990)
Get full text
Journal Article
Synthesis of new camptothecin analogs with improved antitumor activities
NIIZUMA, Satoshi, TSUKAZAKI, Masao, YOSHINARI, Kiyoshi, ENDO, Mika, URA, Masako, TANIMURA, Hiromi, MIYAZAKI, Yoko, TAKASUKA, Tsuyoshi, KAWASHIMA, Akira, NANBA, Eitaro, NAKANO, Kounosuke, OGAWA, Kotaro, SUDA, Hitomi, KOBAYASHI, Kazuko, OKABE, Hisafumi, UMEDA, Isao, SHIMMA, Nobuo, MURATA, Takeshi, OHWADA, Jun, OZAWA, Sawako, FUKUDA, Hiroshi, MURASAKI, Chikako, KOHCHI, Masami, MORIKAMI, Kenji
Published in Bioorganic & medicinal chemistry letters (01.04.2009)
Published in Bioorganic & medicinal chemistry letters (01.04.2009)
Get full text
Journal Article
Synthesis and biological activities of a pH-dependently activated water-soluble prodrug of a novel hexacyclic camptothecin analog
Ohwada, Jun, Ozawa, Sawako, Kohchi, Masami, Fukuda, Hiroshi, Murasaki, Chikako, Suda, Hitomi, Murata, Takeshi, Niizuma, Satoshi, Tsukazaki, Masao, Ori, Kazutomo, Yoshinari, Kiyoshi, Itezono, Yoshiko, Endo, Mika, Ura, Masako, Tanimura, Hiromi, Miyazaki, Yoko, Kawashima, Akira, Nagao, Shunsuke, Namba, Eitarou, Ogawa, Koutarou, Kobayashi, Kazuko, Okabe, Hisafumi, Umeda, Isao, Shimma, Nobuo
Published in Bioorganic & medicinal chemistry letters (15.05.2009)
Published in Bioorganic & medicinal chemistry letters (15.05.2009)
Get full text
Journal Article
Synthesis and Stereochemistry of Hypusine, a New Amino Acid in Bovine Brain
Shiba, Tetsuo, Akiyama, Hitoshi, Umeda, Isao, Okada, Satoshi, Wakamiya, Tateaki
Published in Bulletin of the Chemical Society of Japan (01.03.1982)
Published in Bulletin of the Chemical Society of Japan (01.03.1982)
Get full text
Journal Article
Comparative studies on the antitumor and immunosuppressive effects of the new fluorouracil derivative N4-trimethoxybenzoyl-5'-deoxy-5-fluorocytidine and its parent drug 5'-deoxy-5-fluorouridine
Miwa, M, Ishikawa, T, Eda, H, Ryu, M, Fujimoto, K, Ninomiya, Y, Umeda, I, Yokose, K, Ishitsuka, H
Published in Chemical & pharmaceutical bulletin (1990)
Published in Chemical & pharmaceutical bulletin (1990)
Get full text
Journal Article