An isoform of Dicer protects mammalian stem cells against multiple RNA viruses
Poirier, Enzo Z, Buck, Michael D, Chakravarty, Probir, Carvalho, Joana, Frederico, Bruno, Cardoso, Ana, Healy, Lyn, Ulferts, Rachel, Beale, Rupert, Reis e Sousa, Caetano
Published in Science (American Association for the Advancement of Science) (09.07.2021)
Published in Science (American Association for the Advancement of Science) (09.07.2021)
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Subtractive CRISPR screen identifies the ATG16L1/vacuolar ATPase axis as required for non-canonical LC3 lipidation
Ulferts, Rachel, Marcassa, Elena, Timimi, Lewis, Lee, Liam Changwoo, Daley, Andrew, Montaner, Beatriz, Turner, Suzanne Dawn, Florey, Oliver, Baillie, John Kenneth, Beale, Rupert
Published in Cell reports (Cambridge) (26.10.2021)
Published in Cell reports (Cambridge) (26.10.2021)
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Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp15 endoribonuclease
Canal, Berta, Fujisawa, Ryo, McClure, Allison W, Deegan, Tom D, Wu, Mary, Ulferts, Rachel, Weissmann, Florian, Drury, Lucy S, Bertolin, Agustina P, Zeng, Jingkun, Beale, Rupert, Howell, Michael, Labib, Karim, Diffley, John F X
Published in Biochemical journal (16.07.2021)
Published in Biochemical journal (16.07.2021)
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Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of Nsp14 RNA cap methyltransferase
Basu, Souradeep, Mak, Tiffany, Ulferts, Rachel, Wu, Mary, Deegan, Tom, Fujisawa, Ryo, Tan, Kang Wei, Lim, Chew Theng, Basier, Clovis, Canal, Berta, Curran, Joseph F, Drury, Lucy S, McClure, Allison W, Roberts, Emma L, Weissmann, Florian, Zeisner, Theresa U, Beale, Rupert, Cowling, Victoria H, Howell, Michael, Labib, Karim, Diffley, John F X
Published in Biochemical journal (16.07.2021)
Published in Biochemical journal (16.07.2021)
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Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp14/nsp10 exoribonuclease
Canal, Berta, McClure, Allison W, Curran, Joseph F, Wu, Mary, Ulferts, Rachel, Weissmann, Florian, Zeng, Jingkun, Bertolin, Agustina P, Milligan, Jennifer C, Basu, Souradeep, Drury, Lucy S, Deegan, Tom D, Fujisawa, Ryo, Roberts, Emma L, Basier, Clovis, Labib, Karim, Beale, Rupert, Howell, Michael, Diffley, John F X
Published in Biochemical journal (16.07.2021)
Published in Biochemical journal (16.07.2021)
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Itraconazole Inhibits Enterovirus Replication by Targeting the Oxysterol-Binding Protein
Strating, Jeroen R.P.M., van der Linden, Lonneke, Albulescu, Lucian, Bigay, Joëlle, Arita, Minetaro, Delang, Leen, Leyssen, Pieter, van der Schaar, Hilde M., Lanke, Kjerstin H.W., Thibaut, Hendrik Jan, Ulferts, Rachel, Drin, Guillaume, Schlinck, Nina, Wubbolts, Richard W., Sever, Navdar, Head, Sarah A., Liu, Jun O., Beachy, Philip A., De Matteis, Maria A., Shair, Matthew D., Olkkonen, Vesa M., Neyts, Johan, van Kuppeveld, Frank J.M.
Published in Cell reports (Cambridge) (03.02.2015)
Published in Cell reports (Cambridge) (03.02.2015)
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Selective Serotonin Reuptake Inhibitor Fluoxetine Inhibits Replication of Human Enteroviruses B and D by Targeting Viral Protein 2C
ULFERTS, Rachel, DER LINDEN, Lonneke Van, JAN THIBAUT, Hendrik, LANKE, Kjerstin H. W, LEYSSEN, Pieter, COUTARD, Bruno, DE PALMA, Armando M, CANARD, Bruno, NEYTS, Johan, KUPPEVELD, Frank J. M. Van
Published in Antimicrobial Agents and Chemotherapy (01.04.2013)
Published in Antimicrobial Agents and Chemotherapy (01.04.2013)
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Recruitment of PI4KIIIβ to Coxsackievirus B3 Replication Organelles Is Independent of ACBD3, GBF1, and Arf1
Dorobantu, Cristina M, van der Schaar, Hilde M, Ford, Lauren A, Strating, Jeroen R P M, Ulferts, Rachel, Fang, Ying, Belov, George, van Kuppeveld, Frank J M
Published in Journal of Virology (01.03.2014)
Published in Journal of Virology (01.03.2014)
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Journal Article
Fluoxetine Inhibits Enterovirus Replication by Targeting the Viral 2C Protein in a Stereospecific Manner
Bauer, Lisa, Manganaro, Roberto, Zonsics, Birgit, Strating, Jeroen R. P. M, El Kazzi, Priscila, Lorenzo Lopez, Moira, Ulferts, Rachel, van Hoey, Clara, Maté, Maria J, Langer, Thierry, Coutard, Bruno, Brancale, Andrea, van Kuppeveld, Frank J. M
Published in ACS infectious diseases (13.09.2019)
Published in ACS infectious diseases (13.09.2019)
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The RNA template channel of the RNA-dependent RNA polymerase as a target for development of antiviral therapy of multiple genera within a virus family
van der Linden, Lonneke, Vives-Adrián, Laia, Selisko, Barbara, Ferrer-Orta, Cristina, Liu, Xinran, Lanke, Kjerstin, Ulferts, Rachel, De Palma, Armando M, Tanchis, Federica, Goris, Nesya, Lefebvre, David, De Clercq, Kris, Leyssen, Pieter, Lacroix, Céline, Pürstinger, Gerhard, Coutard, Bruno, Canard, Bruno, Boehr, David D, Arnold, Jamie J, Cameron, Craig E, Verdaguer, Nuria, Neyts, Johan, van Kuppeveld, Frank J M
Published in PLoS pathogens (01.03.2015)
Published in PLoS pathogens (01.03.2015)
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Infecting human hematopoietic stem and progenitor cells with SARS-CoV-2
Huerga Encabo, Hector, Ulferts, Rachel, Sharma, Aneesh, Beale, Rupert, Bonnet, Dominique
Published in STAR protocols (17.12.2021)
Published in STAR protocols (17.12.2021)
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Biochemical Characterization of Arterivirus Nonstructural Protein 11 Reveals the Nidovirus-Wide Conservation of a Replicative Endoribonuclease
NEDIALKOVA, Danny D, ULFERTS, Rachel, VAN DEN BORN, Erwin, LAUBER, Chris, GORBALENYA, Alexander E, ZIEBUHR, John, SNIJDER, Eric J
Published in Journal of Virology (01.06.2009)
Published in Journal of Virology (01.06.2009)
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Journal Article
Crystal Structure and Mechanistic Determinants of SARS Coronavirus Nonstructural Protein 15 Define an Endoribonuclease Family
Ricagno, Stefano, Egloff, Marie-Pierre, Ulferts, Rachel, Coutard, Bruno, Nurizzo, Didier, Campanacci, Valérie, Cambillau, Christian, Ziebuhr, John, Canard, Bruno
Published in Proceedings of the National Academy of Sciences - PNAS (08.08.2006)
Published in Proceedings of the National Academy of Sciences - PNAS (08.08.2006)
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Characterization of Bafinivirus Main Protease Autoprocessing Activities
ULFERTS, Rachel, METTENLEITER, Thomas C, ZIEBUHR, John
Published in Journal of Virology (01.02.2011)
Published in Journal of Virology (01.02.2011)
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Journal Article
The WD40 domain of ATG16L1 is required for its non‐canonical role in lipidation of LC3 at single membranes
Fletcher, Katherine, Ulferts, Rachel, Jacquin, Elise, Veith, Talitha, Gammoh, Noor, Arasteh, Julia M, Mayer, Ulrike, Carding, Simon R, Wileman, Thomas, Beale, Rupert, Florey, Oliver
Published in The EMBO journal (15.02.2018)
Published in The EMBO journal (15.02.2018)
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Journal Article
Conjugation of ATG8s to single membranes at a glance
Figueras-Novoa, Carmen, Timimi, Lewis, Marcassa, Elena, Ulferts, Rachel, Beale, Rupert
Published in Journal of cell science (01.08.2024)
Published in Journal of cell science (01.08.2024)
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Journal Article
Non-canonical autophagy drives alternative ATG8 conjugation to phosphatidylserine
Durgan, Joanne, Lystad, Alf H., Sloan, Katherine, Carlsson, Sven R., Wilson, Michael I., Marcassa, Elena, Ulferts, Rachel, Webster, Judith, Lopez-Clavijo, Andrea F., Wakelam, Michael J., Beale, Rupert, Simonsen, Anne, Oxley, David, Florey, Oliver
Published in Molecular cell (06.05.2021)
Published in Molecular cell (06.05.2021)
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Usp25-Erlin1/2 activity limits cholesterol flux to restrict virus infection
Teo, Qi Wen, Wong, Ho Him, Heunis, Tiaan, Stancheva, Viktoriya, Hachim, Asmaa, Lv, Huibin, Siu, Lewis, Ho, Julian, Lan, Yun, Mok, Chris Ka Pun, Ulferts, Rachel, Sanyal, Sumana
Published in Developmental cell (20.11.2023)
Published in Developmental cell (20.11.2023)
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