Hydrophobic ion pairing of a minocycline/Ca2+/AOT complex for preparation of drug-loaded PLGA nanoparticles with improved sustained release
Holmkvist, Alexander Dontsios, Friberg, Annika, Nilsson, Ulf J., Schouenborg, Jens
Published in International journal of pharmaceutics (29.02.2016)
Published in International journal of pharmaceutics (29.02.2016)
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Journal Article
1H-1,2,3-Triazol-1-yl thiodigalactoside derivatives as high affinity galectin-3 inhibitors
Salameh, Bader A., Cumpstey, Ian, Sundin, Anders, Leffler, Hakon, Nilsson, Ulf J.
Published in Bioorganic & medicinal chemistry (15.07.2010)
Published in Bioorganic & medicinal chemistry (15.07.2010)
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Journal Article
Discovery and Optimization of the First Highly Effective and Orally Available Galectin‑3 Inhibitors for Treatment of Fibrotic Disease
Zetterberg, Fredrik R., MacKinnon, Alison, Brimert, Thomas, Gravelle, Lise, Johnsson, Richard E., Kahl-Knutson, Barbro, Leffler, Hakon, Nilsson, Ulf J., Pedersen, Anders, Peterson, Kristoffer, Roper, James A., Schambye, Hans, Slack, Robert J., Tantawi, Susan
Published in Journal of medicinal chemistry (13.10.2022)
Published in Journal of medicinal chemistry (13.10.2022)
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Journal Article
An Orally Active Galectin-3 Antagonist Inhibits Lung Adenocarcinoma Growth and Augments Response to PD-L1 Blockade
Vuong, Lynda, Kouverianou, Eleni, Rooney, Claire M, McHugh, Brian J, Howie, Sarah E M, Gregory, Christopher D, Forbes, Stuart J, Henderson, Neil C, Zetterberg, Fredrik R, Nilsson, Ulf J, Leffler, Hakon, Ford, Paul, Pedersen, Anders, Gravelle, Lise, Tantawi, Susan, Schambye, Hans, Sethi, Tariq, MacKinnon, Alison C
Published in Cancer research (Chicago, Ill.) (01.04.2019)
Published in Cancer research (Chicago, Ill.) (01.04.2019)
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Journal Article
Double Affinity Amplification of Galectin-Ligand Interactions through Arginine-Arene Interactions: Synthetic, Thermodynamic, and Computational Studies with Aromatic Diamido Thiodigalactosides
Cumpstey, Ian, Salomonsson, Emma, Sundin, Anders, Leffler, Hakon, Nilsson, Ulf J.
Published in Chemistry : a European journal (01.01.2008)
Published in Chemistry : a European journal (01.01.2008)
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Journal Article
The glomerular endothelial cell coat is essential for glomerular filtration
Fridén, Vincent, Oveland, Eystein, Tenstad, Olav, Ebefors, Kerstin, Nyström, Jenny, Nilsson, Ulf A., Haraldsson, Börje
Published in Kidney international (01.06.2011)
Published in Kidney international (01.06.2011)
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Journal Article
Pathological lymphangiogenesis is modulated by galectin-8-dependent crosstalk between podoplanin and integrin-associated VEGFR-3
Chen, Wei-Sheng, Cao, Zhiyi, Sugaya, Satoshi, Lopez, Maria J., Sendra, Victor G., Laver, Nora, Leffler, Hakon, Nilsson, Ulf J., Fu, Jianxin, Song, Jianhua, Xia, Lijun, Hamrah, Pedram, Panjwani, Noorjahan
Published in Nature communications (12.04.2016)
Published in Nature communications (12.04.2016)
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Journal Article
Ligand Sulfur Oxidation State Progressively Alters Galectin-3-Ligand Complex Conformations To Induce Affinity-Influencing Hydrogen Bonds
Mahanti, Mukul, Pal, Kumar Bhaskar, Kumar, Rohit, Schulze, Markus, Leffler, Hakon, Logan, Derek T., Nilsson, Ulf J.
Published in Journal of medicinal chemistry (09.11.2023)
Published in Journal of medicinal chemistry (09.11.2023)
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Journal Article
A Selective Galactose–Coumarin-Derived Galectin‑3 Inhibitor Demonstrates Involvement of Galectin-3-glycan Interactions in a Pulmonary Fibrosis Model
Rajput, Vishal K, MacKinnon, Alison, Mandal, Santanu, Collins, Patrick, Blanchard, Helen, Leffler, Hakon, Sethi, Tariq, Schambye, Hans, Mukhopadhyay, Balaram, Nilsson, Ulf J
Published in Journal of medicinal chemistry (08.09.2016)
Published in Journal of medicinal chemistry (08.09.2016)
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Journal Article
Galectin binding to cells and glycoproteins with genetically modified glycosylation reveals galectin–glycan specificities in a natural context
Nielsen, Mathias Ingemann, Stegmayr, John, Grant, Oliver C., Yang, Zhang, Nilsson, Ulf J., Boos, Irene, Carlsson, Michael C., Woods, Robert J., Unverzagt, Carlo, Leffler, Hakon, Wandall, Hans H.
Published in The Journal of biological chemistry (28.12.2018)
Published in The Journal of biological chemistry (28.12.2018)
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Journal Article
Discovery of Selective and Orally Available Galectin‑1 Inhibitors
Zetterberg, Fredrik R., Diehl, Carl, Håkansson, Maria, Kahl-Knutson, Barbro, Leffler, Hakon, Nilsson, Ulf J., Peterson, Kristoffer, Roper, James A., Slack, Robert J.
Published in Journal of medicinal chemistry (28.12.2023)
Published in Journal of medicinal chemistry (28.12.2023)
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Journal Article
N‐BAR and F‐BAR proteins—endophilin‐A3 and PSTPIP1—control clathrin‐independent endocytosis of L1CAM
Lemaigre, Camille, Ceuppens, Apolline, Valades‐Cruz, Cesar Augusto, Ledoux, Benjamin, Vanbeneden, Bastien, Hassan, Mujtaba, Zetterberg, Fredrik R., Nilsson, Ulf J., Johannes, Ludger, Wunder, Christian, Renard, Henri‐François, Morsomme, Pierre
Published in Traffic (Copenhagen, Denmark) (01.04.2023)
Published in Traffic (Copenhagen, Denmark) (01.04.2023)
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Journal Article
Systematic Tuning of Fluoro-galectin‑3 Interactions Provides Thiodigalactoside Derivatives with Single-Digit nM Affinity and High Selectivity
Peterson, Kristoffer, Kumar, Rohit, Stenström, Olof, Verma, Priya, Verma, Prashant R, Håkansson, Maria, Kahl-Knutsson, Barbro, Zetterberg, Fredrik, Leffler, Hakon, Akke, Mikael, Logan, Derek T, Nilsson, Ulf J
Published in Journal of medicinal chemistry (08.02.2018)
Published in Journal of medicinal chemistry (08.02.2018)
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Journal Article
Monosaccharide Derivatives with Low‐Nanomolar Lectin Affinity and High Selectivity Based on Combined Fluorine–Amide, Phenyl–Arginine, Sulfur–π, and Halogen Bond Interactions
Zetterberg, Fredrik R., Peterson, Kristoffer, Johnsson, Richard E., Brimert, Thomas, Håkansson, Maria, Logan, Derek T., Leffler, Hakon, Nilsson, Ulf J.
Published in ChemMedChem (22.01.2018)
Published in ChemMedChem (22.01.2018)
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Journal Article
Novel inhibitory effect of galectin-3 on the respiratory burst induced by Staphylococcus aureus in human neutrophils
Venkatakrishnan, Vignesh, Elmwall, Jonas, Lahiri, Trisha, Sundqvist, Martina, Bergqvist, Linda, Leffler, Hakon, Nilsson, Ulf J, Welin, Amanda, Bylund, Johan, Karlsson-Bengtsson, Anna
Published in Glycobiology (Oxford) (21.06.2023)
Published in Glycobiology (Oxford) (21.06.2023)
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Journal Article
Galectin inhibitory disaccharides promote tumour immunity in a breast cancer model
Stannard, Kimberley A, Collins, Patrick M, Ito, Koichi, Sullivan, Emily M, Scott, Stacy A, Gabutero, Elwyn, Darren Grice, I, Low, Pauline, Nilsson, Ulf. J, Leffler, Hakon, Blanchard, Helen, Ralph, Stephen J
Published in Cancer letters (28.12.2010)
Published in Cancer letters (28.12.2010)
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Journal Article
Structural characterization of human galectin‐4 C‐terminal domain: elucidating the molecular basis for recognition of glycosphingolipids, sulfated saccharides and blood group antigens
Bum‐Erdene, Khuchtumur, Leffler, Hakon, Nilsson, Ulf J, Blanchard, Helen
Published in The FEBS journal (01.09.2015)
Published in The FEBS journal (01.09.2015)
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