Effect of canagliflozin on renal threshold for glucose, glycemia, and body weight in normal and diabetic animal models
Liang, Yin, Arakawa, Kenji, Ueta, Kiichiro, Matsushita, Yasuaki, Kuriyama, Chiaki, Martin, Tonya, Du, Fuyong, Liu, Yi, Xu, June, Conway, Bruce, Conway, Jamie, Polidori, David, Ways, Kirk, Demarest, Keith
Published in PloS one (15.02.2012)
Published in PloS one (15.02.2012)
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Vadadustat for anemia in chronic kidney disease patients on peritoneal dialysis: A phase 3 open‐label study in Japan
Nangaku, Masaomi, Kondo, Kazuoki, Takabe, Souichirou, Ueta, Kiichiro, Kaneko, Genki, Otsuka, Makiko, Kawaguchi, Yutaka, Komatsu, Yasuhiro
Published in Therapeutic apheresis and dialysis (01.10.2021)
Published in Therapeutic apheresis and dialysis (01.10.2021)
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A phase 3, open‐label, single‐arm study of vadadustat for anemia in chronic kidney disease for Japanese patients on hemodialysis not receiving erythropoiesis‐stimulating agents
Nangaku, Masaomi, Kondo, Kazuoki, Takabe, Souichirou, Ueta, Kiichiro, Tandai, Tsubasa, Kawaguchi, Yutaka, Komatsu, Yasuhiro
Published in Therapeutic apheresis and dialysis (01.02.2022)
Published in Therapeutic apheresis and dialysis (01.02.2022)
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Intestinal Sodium Glucose Cotransporter 1 Inhibition Enhances Glucagon-Like Peptide-1 Secretion in Normal and Diabetic Rodents
Oguma, Takahiro, Nakayama, Keiko, Kuriyama, Chiaki, Matsushita, Yasuaki, Yoshida, Kumiko, Hikida, Kumiko, Obokata, Naoyuki, Tsuda-Tsukimoto, Minoru, Saito, Akira, Arakawa, Kenji, Ueta, Kiichiro, Shiotani, Masaharu
Published in The Journal of pharmacology and experimental therapeutics (01.09.2015)
Published in The Journal of pharmacology and experimental therapeutics (01.09.2015)
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Beneficial effects of canagliflozin in combination with pioglitazone on insulin sensitivity in rodent models of obese type 2 diabetes
Watanabe, Yoshinori, Nakayama, Keiko, Taniuchi, Nobuhiko, Horai, Yasushi, Kuriyama, Chiaki, Ueta, Kiichiro, Arakawa, Kenji, Senbonmatsu, Takaaki, Shiotani, Masaharu
Published in PloS one (23.01.2015)
Published in PloS one (23.01.2015)
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Analysis of the effect of canagliflozin on renal glucose reabsorption and progression of hyperglycemia in zucker diabetic Fatty rats
Kuriyama, Chiaki, Xu, Jun Zhi, Lee, Seunghun Paul, Qi, Jenson, Kimata, Hirotaka, Kakimoto, Tetsuhiro, Nakayama, Keiko, Watanabe, Yoshinori, Taniuchi, Nobuhiko, Hikida, Kumiko, Matsushita, Yasuaki, Arakawa, Kenji, Saito, Akira, Ueta, Kiichiro, Shiotani, Masaharu
Published in The Journal of pharmacology and experimental therapeutics (01.11.2014)
Published in The Journal of pharmacology and experimental therapeutics (01.11.2014)
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The effect of combined treatment with canagliflozin and teneligliptin on glucose intolerance in Zucker diabetic fatty rats
Oguma, Takahiro, Kuriyama, Chiaki, Nakayama, Keiko, Matsushita, Yasuaki, Yoshida, Kumiko, Kiuchi, Satoko, Ikenaga, Yuka, Nakamaru, Yoshinobu, Hikida, Kumiko, Saito, Akira, Arakawa, Kenji, Oka, Kozo, Ueta, Kiichiro, Shiotani, Masaharu
Published in Journal of pharmacological sciences (01.04.2015)
Published in Journal of pharmacological sciences (01.04.2015)
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Changes in glucose-induced plasma active glucagon-like peptide-1 levels by co-administration of sodium–glucose cotransporter inhibitors with dipeptidyl peptidase-4 inhibitors in rodents
Oguma, Takahiro, Kuriyama, Chiaki, Nakayama, Keiko, Matsushita, Yasuaki, Hikida, Kumiko, Tsuda-Tsukimoto, Minoru, Saito, Akira, Arakawa, Kenji, Ueta, Kiichiro, Minami, Masabumi, Shiotani, Masaharu
Published in Journal of pharmacological sciences (01.12.2016)
Published in Journal of pharmacological sciences (01.12.2016)
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Synthesis and Biological Evaluation of Thiophene-C-glucosides as Sodium-Dependent Glucose Cotransporter 2 Inhibitors
Sakamaki, Shigeki, Kawanishi, Eiji, Koga, Yuichi, Yamamoto, Yasuo, Kuriyama, Chiaki, Matsushita, Yasuaki, Ueta, Kiichiro, Nomura, Sumihiro
Published in Chemical & pharmaceutical bulletin (01.10.2013)
Published in Chemical & pharmaceutical bulletin (01.10.2013)
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Journal Article
Reduction of Renal Transport Maximum for Glucose by Inhibition of Na+-Glucose Cotransporter Suppresses Blood Glucose Elevation in Dogs
Ueta, Kiichiro, Yoneda, Hikaru, Oku, Akira, Nishiyama, Shinsuke, Saito, Akira, Arakawa, Kenji
Published in Biological & Pharmaceutical Bulletin (2006)
Published in Biological & Pharmaceutical Bulletin (2006)
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Na+-Glucose Cotransporter (SGLT) Inhibitors as Antidiabetic Agents. 4. Synthesis and Pharmacological Properties of 4‘-Dehydroxyphlorizin Derivatives Substituted on the B Ring
Tsujihara, Kenji, Hongu, Mitsuya, Saito, Kunio, Kawanishi, Hiroyuki, Kuriyama, Kayoko, Matsumoto, Mamoru, Oku, Akira, Ueta, Kiichiro, Tsuda, Minoru, Saito, Akira
Published in Journal of medicinal chemistry (30.12.1999)
Published in Journal of medicinal chemistry (30.12.1999)
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Journal Article
Phase 3 Randomized Study Comparing Vadadustat with Darbepoetin Alfa for Anemia in Japanese Patients with Nondialysis-Dependent CKD
Nangaku, Masaomi, Kondo, Kazuoki, Kokado, Yoshimasa, Ueta, Kiichiro, Kaneko, Genki, Tandai, Tsubasa, Kawaguchi, Yutaka, Komatsu, Yasuhiro
Published in Journal of the American Society of Nephrology (01.07.2021)
Published in Journal of the American Society of Nephrology (01.07.2021)
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Journal Article
Efficacy and safety of vadadustat compared with darbepoetin alfa in Japanese anemic patients on hemodialysis: a Phase 3, multicenter, randomized, double-blind study
Nangaku, Masaomi, Kondo, Kazuoki, Ueta, Kiichiro, Kokado, Yoshimasa, Kaneko, Genki, Matsuda, Hiroki, Kawaguchi, Yutaka, Komatsu, Yasuhiro
Published in Nephrology, dialysis, transplantation (01.09.2021)
Published in Nephrology, dialysis, transplantation (01.09.2021)
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Journal Article
Inhibitory effect of hyperglycemia on insulin-induced Akt/protein kinase B activation in skeletal muscle
Oku, Akira, Nawano, Masao, Ueta, Kiichiro, Fujita, Takuya, Umebayashi, Itsuro, Arakawa, Kenji, Kano-Ishihara, Tomomi, Saito, Akira, Anai, Motonobu, Funaki, Makoto, Kikuchi, Masayoshi, Oka, Yoshitomo, Asano, Tomoichiro
Published in American journal of physiology: endocrinology and metabolism (01.05.2001)
Published in American journal of physiology: endocrinology and metabolism (01.05.2001)
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Factors affecting responsiveness of vadadustat in patients with anemia associated with chronic kidney disease: a post-hoc subgroup analysis of Japanese phase 3 randomized studies
Nangaku, Masaomi, Ueta, Kiichiro, Nishimura, Kenichi, Sasaki, Kazuyo, Hashimoto, Takafumi
Published in Clinical and experimental nephrology (01.05.2024)
Published in Clinical and experimental nephrology (01.05.2024)
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Journal Article
Discovery of Canagliflozin, a Novel C-Glucoside with Thiophene Ring, as Sodium-Dependent Glucose Cotransporter 2 Inhibitor for the Treatment of Type 2 Diabetes Mellitus
Nomura, Sumihiro, Sakamaki, Shigeki, Hongu, Mitsuya, Kawanishi, Eiji, Koga, Yuichi, Sakamoto, Toshiaki, Yamamoto, Yasuo, Ueta, Kiichiro, Kimata, Hirotaka, Nakayama, Keiko, Tsuda-Tsukimoto, Minoru
Published in Journal of medicinal chemistry (09.09.2010)
Published in Journal of medicinal chemistry (09.09.2010)
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Characteristics of Japanese patients with non-dialysis-dependent chronic kidney disease initiating treatment for anemia: a retrospective real-world database study
Kokado, Yoshimasa, Ishii, Manabu, Ueta, Kiichiro, Yamamoto, Hiroyuki, Kumamaru, Hiraku, Isshiki, Masaaki, Demiya, Sven, Miyata, Hiroaki
Published in Current medical research and opinion (02.12.2022)
Published in Current medical research and opinion (02.12.2022)
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Journal Article
Hyperglycemia Impairs the Insulin Signaling Step between PI 3-Kinase and Akt/PKB Activations in ZDF Rat Liver
Nawano, Masao, Ueta, Kiichiro, Oku, Akira, Arakawa, Kenji, Saito, Akira, Funaki, Makoto, Anai, Motonobu, Kikuchi, Masatoshi, Oka, Yoshitomo, Asano, Tomoichiro
Published in Biochemical and biophysical research communications (09.12.1999)
Published in Biochemical and biophysical research communications (09.12.1999)
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Journal Article
Antihyperglycemic Effect of T-1095 via Inhibition of Renal Na+ -Glucose Cotransporters in Streptozotocin-Induced Diabetic Rats
OKU, Akira, UETA, Kiichiro, ARAKAWA, KENJI, KANO-ISHIHARA, Tomomi, MATSUMOTO, Mamoru, ADACHI, Tetsuya, YASUDA, Koichiro, TSUDA, Kinsuke, SAITO, Akira
Published in Biological & pharmaceutical bulletin (01.12.2000)
Published in Biological & pharmaceutical bulletin (01.12.2000)
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Journal Article
Correcting Postprandial Hyperglycemia in Zucker Diabetic Fatty Rats With an SGLT2 Inhibitor Restores Glucose Effectiveness in the Liver and Reduces Insulin Resistance in Skeletal Muscle
O'Brien, Tracy P, Jenkins, Erin C, Estes, Shanea K, Castaneda, Antonio V, Ueta, Kiichiro, Farmer, Tiffany D, Puglisi, Allison E, Swift, Larry L, Printz, Richard L, Shiota, Masakazu
Published in Diabetes (New York, N.Y.) (01.05.2017)
Published in Diabetes (New York, N.Y.) (01.05.2017)
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