Aristeromycin and DZNeP cause growth inhibition of prostate cancer via induction of mir-26a
Uchiyama, Noriko, Tanaka, Yukiya, Kawamoto, Tomohiro
Published in European journal of pharmacology (05.10.2017)
Published in European journal of pharmacology (05.10.2017)
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Discovery of a Novel and Brain-Penetrant O‑GlcNAcase Inhibitor via Virtual Screening, Structure-Based Analysis, and Rational Lead Optimization
Tawada, Michiko, Fushimi, Makoto, Masuda, Kei, Sun, Huikai, Uchiyama, Noriko, Kosugi, Yohei, Lane, Weston, Tjhen, Richard, Endo, Satoshi, Koike, Tatsuki
Published in Journal of medicinal chemistry (28.01.2021)
Published in Journal of medicinal chemistry (28.01.2021)
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Discovery of Novel Allosteric Inhibitors of Deoxyhypusine Synthase
Tanaka, Yuta, Kurasawa, Osamu, Yokota, Akihiro, Klein, Michael G, Ono, Koji, Saito, Bunnai, Matsumoto, Shigemitsu, Okaniwa, Masanori, Ambrus-Aikelin, Geza, Morishita, Daisuke, Kitazawa, Satoshi, Uchiyama, Noriko, Ogawa, Kazumasa, Kimura, Hiromichi, Imamura, Shinichi
Published in Journal of medicinal chemistry (26.03.2020)
Published in Journal of medicinal chemistry (26.03.2020)
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Discovery of 3‑Benzyl-1‑(trans-4-((5-cyanopyridin-2-yl)amino)cyclohexyl)-1-arylurea Derivatives as Novel and Selective Cyclin-Dependent Kinase 12 (CDK12) Inhibitors
Ito, Masahiro, Tanaka, Toshio, Toita, Akinori, Uchiyama, Noriko, Kokubo, Hironori, Morishita, Nao, Klein, Michael G, Zou, Hua, Murakami, Morio, Kondo, Mitsuyo, Sameshima, Tomoya, Araki, Shinsuke, Endo, Satoshi, Kawamoto, Tomohiro, Morin, Gregg B, Aparicio, Samuel A, Nakanishi, Atsushi, Maezaki, Hironobu, Imaeda, Yasuhiro
Published in Journal of medicinal chemistry (13.09.2018)
Published in Journal of medicinal chemistry (13.09.2018)
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A novel glycogen synthase kinase‐3 inhibitor 2‐methyl‐5‐(3‐{4‐[(S )‐methylsulfinyl]phenyl}‐1‐benzofuran‐5‐yl)‐1,3,4‐oxadiazole decreases tau phosphorylation and ameliorates cognitive deficits in a transgenic model of Alzheimer’s disease
Onishi, Tomohiro, Iwashita, Hiroki, Uno, Yumiko, Kunitomo, Jun, Saitoh, Morihisa, Kimura, Eiji, Fujita, Hisashi, Uchiyama, Noriko, Kori, Masakuni, Takizawa, Masayuki
Published in Journal of neurochemistry (01.12.2011)
Published in Journal of neurochemistry (01.12.2011)
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CLK-dependent exon recognition and conjoined gene formation revealed with a novel small molecule inhibitor
Funnell, Tyler, Tasaki, Shinya, Oloumi, Arusha, Araki, Shinsuke, Kong, Esther, Yap, Damian, Nakayama, Yusuke, Hughes, Christopher S., Cheng, S.-W. Grace, Tozaki, Hirokazu, Iwatani, Misa, Sasaki, Satoshi, Ohashi, Tomohiro, Miyazaki, Tohru, Morishita, Nao, Morishita, Daisuke, Ogasawara-Shimizu, Mari, Ohori, Momoko, Nakao, Shoichi, Karashima, Masatoshi, Sano, Masaya, Murai, Aiko, Nomura, Toshiyuki, Uchiyama, Noriko, Kawamoto, Tomohiro, Hara, Ryujiro, Nakanishi, Osamu, Shumansky, Karey, Rosner, Jamie, Wan, Adrian, McKinney, Steven, Morin, Gregg B., Nakanishi, Atsushi, Shah, Sohrab, Toyoshiba, Hiroyoshi, Aparicio, Samuel
Published in Nature communications (23.02.2017)
Published in Nature communications (23.02.2017)
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TAK-960, a novel, orally available, selective inhibitor of polo-like kinase 1, shows broad-spectrum preclinical antitumor activity in multiple dosing regimens
Hikichi, Yuichi, Honda, Kohei, Hikami, Kouki, Miyashita, Hitoshi, Kaieda, Isao, Murai, Saomi, Uchiyama, Noriko, Hasegawa, Maki, Kawamoto, Tomohiro, Sato, Takashi, Ichikawa, Takashi, Cao, Sheldon, Nie, Zhe, Zhang, Lilly, Yang, Johnny, Kuida, Keisuke, Kupperman, Erik
Published in Molecular cancer therapeutics (01.03.2012)
Published in Molecular cancer therapeutics (01.03.2012)
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Discovery of a Novel Series of Pyrazolo[1,5-a]pyrimidine-Based Phosphodiesterase 2A Inhibitors Structurally Different from N-((1S)-1-(3-Fluoro-4-(trifluoromethoxy)phenyl)-2-methoxyethyl)-7-methoxy-2-oxo-2,3-dihydropyrido[2,3-b]pyrazine-4(1H)-carboxamide (TAK-915), for the Treatment of Cognitive Disorders
Mikami, Satoshi, Kawasaki, Masanori, Ikeda, Shuhei, Negoro, Nobuyuki, Nakamura, Shinji, Nomura, Izumi, Ashizawa, Tomoko, Kokubo, Hironori, Hoffman, Isaac Dylan, Zou, Hua, Oki, Hideyuki, Uchiyama, Noriko, Hiura, Yuuto, Miyamoto, Maki, Itou, Yuuki, Nakashima, Masato, Iwashita, Hiroki, Taniguchi, Takahiko
Published in Chemical & pharmaceutical bulletin (2017)
Published in Chemical & pharmaceutical bulletin (2017)
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Molecular mechanism and potential target indication of TAK-931, a novel CDC7-selective inhibitor
Iwai, Kenichi, Nambu, Tadahiro, Dairiki, Ryo, Ohori, Momoko, Yu, Jie, Burke, Kristine, Gotou, Masamitsu, Yamamoto, Yukiko, Ebara, Shunsuke, Shibata, Sachio, Hibino, Ryosuke, Nishizawa, Satoru, Miyazaki, Tohru, Homma, Misaki, Oguro, Yuya, Imada, Takashi, Cho, Nobuo, Uchiyama, Noriko, Kogame, Akifumi, Takeuchi, Toshiyuki, Kurasawa, Osamu, Yamanaka, Kazunori, Niu, Huifeng, Ohashi, Akihiro
Published in Science advances (01.05.2019)
Published in Science advances (01.05.2019)
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Discovery of TAK-960: An orally available small molecule inhibitor of polo-like kinase 1 (PLK1)
Nie, Zhe, Feher, Victoria, Natala, Srinivasa, McBride, Christopher, Kiryanov, Andre, Jones, Benjamin, Lam, Betty, Liu, Yan, Kaldor, Stephen, Stafford, Jeffrey, Hikami, Kouki, Uchiyama, Noriko, Kawamoto, Tomohiro, Hikichi, Yuichi, Matsumoto, Shin-ichi, Amano, Nobuyuki, Zhang, Lilly, Hosfield, David, Skene, Robert, Zou, Hua, Cao, Xiaodong, Ichikawa, Takashi
Published in Bioorganic & medicinal chemistry letters (15.06.2013)
Published in Bioorganic & medicinal chemistry letters (15.06.2013)
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Structure-based design and SAR development of 5,6-dihydroimidazolo[1,5-f]pteridine derivatives as novel Polo-like kinase-1 inhibitors
Kiryanov, Andre, Natala, Srinivasa, Jones, Benjamin, McBride, Christopher, Feher, Victoria, Lam, Betty, Liu, Yan, Honda, Kouhei, Uchiyama, Noriko, Kawamoto, Tomohiro, Hikichi, Yuichi, Zhang, Lilly, Hosfield, David, Skene, Robert, Zou, Hua, Stafford, Jeffrey, Cao, Xiaodong, Ichikawa, Takashi
Published in Bioorganic & medicinal chemistry letters (01.03.2017)
Published in Bioorganic & medicinal chemistry letters (01.03.2017)
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Effect of Cathepsin K Inhibitors on Bone Resorption
Teno, Naoki, Masuya, Keiichi, Ehara, Takeru, Kosaka, Takatoshi, Miyake, Takahiro, Irie, Osamu, Hitomi, Yuko, Matsuura, Naoko, Umemura, Ichiro, Iwasaki, Genji, Fukaya, Hiroaki, Toriyama, Kazuhiro, Uchiyama, Noriko, Nonomura, Kazuhiko, Sugiyama, Ikuo, Kometani, Motohiko
Published in Journal of medicinal chemistry (11.09.2008)
Published in Journal of medicinal chemistry (11.09.2008)
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The Way of the Human Being Power Upbringing Education Class in the Maritime Technology Department: One Consideration of the Questionnaire Result from 2017 through 2019
UCHIYAMA, Noriko
Published in The Bulletin of National Institute of Technology, Hiroshima College (2020)
Published in The Bulletin of National Institute of Technology, Hiroshima College (2020)
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Reciprocal roles for CCAAT/enhancer binding protein (C/EBP) and PU.1 transcription factors in Langerhans cell commitment
Iwama, Atsushi, Osawa, Mitsujiro, Hirasawa, Ryutaro, Uchiyama, Noriko, Kaneko, Shin, Onodera, Masafumi, Shibuya, Kazuko, Shibuya, Akira, Vinson, Charles, Tenen, Daniel G, Nakauchi, Hiromitsu
Published in The Journal of experimental medicine (04.03.2002)
Published in The Journal of experimental medicine (04.03.2002)
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Study on the Electronic System of Overnight Stay Application for Our Student Dormitory
KATO, Hiroaki, KANEKO, Haruo, KISHI, Takuma, UCHIYAMA, Noriko, KOBAYASHI, Go, OKAYAMA, Masato
Published in The Bulletin of National Institute of Technology, Hiroshima College (31.03.2023)
Published in The Bulletin of National Institute of Technology, Hiroshima College (31.03.2023)
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