Activating mutations in the NT5C2 nucleotidase gene drive chemotherapy resistance in relapsed ALL
Tzoneva, Gannie, Perez-Garcia, Arianne, Carpenter, Zachary, Khiabanian, Hossein, Tosello, Valeria, Allegretta, Maddalena, Paietta, Elisabeth, Racevskis, Janis, Rowe, Jacob M, Tallman, Martin S, Paganin, Maddalena, Basso, Giuseppe, Hof, Jana, Kirschner-Schwabe, Renate, Palomero, Teresa, Rabadan, Raul, Ferrando, Adolfo
Published in Nature medicine (01.03.2013)
Published in Nature medicine (01.03.2013)
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Journal Article
Mutational landscape, clonal evolution patterns, and role of RAS mutations in relapsed acute lymphoblastic leukemia
Oshima, Koichi, Khiabanian, Hossein, da Silva-Almeida, Ana C., Tzoneva, Gannie, Abate, Francesco, Ambesi-Impiombato, Alberto, Sanchez-Martin, Marta, Carpenter, Zachary, Penson, Alex, Perez-Garcia, Arianne, Eckert, Cornelia, Nicolas, Concepción, Balbin, Milagros, Sulis, Maria Luisa, Kato, Motohiro, Koh, Katsuyoshi, Paganin, Maddalena, Basso, Giuseppe, Gastier-Foster, Julie M., Devidas, Meenakshi, Loh, Mignon L., Kirschner-Schwabe, Renate, Palomero, Teresa, Rabadan, Raul, Ferrando, Adolfo A.
Published in Proceedings of the National Academy of Sciences - PNAS (04.10.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (04.10.2016)
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Journal Article
Negative feedback–defective PRPS1 mutants drive thiopurine resistance in relapsed childhood ALL
Li, Benshang, Li, Hui, Bai, Yun, Kirschner-Schwabe, Renate, Yang, Jun J, Chen, Yao, Lu, Gang, Tzoneva, Gannie, Ma, Xiaotu, Wu, Tongmin, Li, Wenjing, Lu, Haisong, Ding, Lixia, Liang, Huanhuan, Huang, Xiaohang, Yang, Minjun, Jin, Lei, Kang, Hui, Chen, Shuting, Du, Alicia, Shen, Shuhong, Ding, Jianping, Chen, Hongzhuan, Chen, Jing, von Stackelberg, Arend, Gu, Longjun, Zhang, Jinghui, Ferrando, Adolfo, Tang, Jingyan, Wang, Shengyue, Zhou, Bin-Bing S
Published in Nature medicine (01.06.2015)
Published in Nature medicine (01.06.2015)
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Journal Article
Structure and Mechanisms of NT5C2 Mutations Driving Thiopurine Resistance in Relapsed Lymphoblastic Leukemia
Dieck, Chelsea L., Tzoneva, Gannie, Forouhar, Farhad, Carpenter, Zachary, Ambesi-Impiombato, Alberto, Sánchez-Martín, Marta, Kirschner-Schwabe, Renate, Lew, Scott, Seetharaman, Jayaraman, Tong, Liang, Ferrando, Adolfo A.
Published in Cancer cell (09.07.2018)
Published in Cancer cell (09.07.2018)
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Journal Article
Clonal evolution mechanisms in NT5C2 mutant-relapsed acute lymphoblastic leukaemia
Tzoneva, Gannie, Dieck, Chelsea L., Oshima, Koichi, Ambesi-Impiombato, Alberto, Sánchez-Martín, Marta, Madubata, Chioma J., Khiabanian, Hossein, Yu, Jiangyan, Waanders, Esme, Iacobucci, Ilaria, Sulis, Maria Luisa, Kato, Motohiro, Koh, Katsuyoshi, Paganin, Maddalena, Basso, Giuseppe, Gastier-Foster, Julie M., Loh, Mignon L., Kirschner-Schwabe, Renate, Mullighan, Charles G., Rabadan, Raul, Ferrando, Adolfo A.
Published in Nature (London) (25.01.2018)
Published in Nature (London) (25.01.2018)
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Journal Article
Recent advances on NOTCH signaling in T-ALL
Tzoneva, Gannie, Ferrando, Adolfo A
Published in Current topics in microbiology and immunology (01.01.2012)
Published in Current topics in microbiology and immunology (01.01.2012)
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Journal Article
Two founder variants account for over 90% of pathogenic BRCA alleles in the Orkney and Shetland Isles in Scotland
Kerr, Shona M., Klaric, Lucija, Muckian, Marisa D., Cowan, Emma, Snadden, Lesley, Tzoneva, Gannie, Shuldiner, Alan R., Miedzybrodzka, Zosia, Wilson, James F.
Published in European journal of human genetics : EJHG (22.10.2024)
Published in European journal of human genetics : EJHG (22.10.2024)
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Journal Article
Functional modeling of human lysosomal acid alpha-glucosidase variants
Zhang, Xiaoli, Hwang-Wong, Elizabeth, Tzoneva, Gannie, Rothman, Nyanza, Bhargava, Ajay Bhargava, Germino, Mary, Panagis, Lampros, Shuldiner, Alan, Economides, Aris, Cygnar, Katherine
Published in Molecular genetics and metabolism (01.02.2022)
Published in Molecular genetics and metabolism (01.02.2022)
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Journal Article
Clinical case study meets population cohort: identification of a BRCA1 pathogenic founder variant in Orcadians
Kerr, Shona M, Cowan, Emma, Klaric, Lucija, Bell, Christine, O'Sullivan, Dawn, Buchanan, David, Grzymski, Joseph J, van Hout, Cristopher V, Tzoneva, Gannie, Shuldiner, Alan R, Wilson, James F, Miedzybrodzka, Zosia
Published in European journal of human genetics : EJHG (01.05.2023)
Published in European journal of human genetics : EJHG (01.05.2023)
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Journal Article
Genetic and functional evidence links a missense variant in B4GALT1 to lower LDL and fibrinogen
Montasser, May E, Van Hout, Cristopher V, Miloscio, Lawrence, Howard, Alicia D, Rosenberg, Avraham, Callaway, Myrasol, Shen, Biao, Li, Ning, Locke, Adam E, Verweij, Niek, De, Tanima, Ferreira, Manuel A, Lotta, Luca A, Baras, Aris, Daly, Thomas J, Hartford, Suzanne A, Lin, Wei, Mao, Yuan, Ye, Bin, White, Derek, Gong, Guochun, Perry, James A, Ryan, Kathleen A, Fang, Qing, Tzoneva, Gannie, Pefanis, Evangelos, Hunt, Charleen, Tang, Yajun, Lee, Lynn, Sztalryd-Woodle, Carole, Mitchell, Braxton D, Healy, Matthew, Streeten, Elizabeth A, Taylor, Simeon I, O'Connell, Jeffrey R, Economides, Aris N, Della Gatta, Giusy, Shuldiner, Alan R
Published in Science (American Association for the Advancement of Science) (03.12.2021)
Published in Science (American Association for the Advancement of Science) (03.12.2021)
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Journal Article
Mechanisms of NT5C2 mutations Driving Thiopurine Resistance in Acute Lymphoblastic Leukemia
Dieck, Chelsea, Tzoneva, Gannie, Forouhar, Farhad, Carpenter, Zachary, Ambesi-Impiombato, Alberto, Sanchez-Martin, Marta, Tong, Liang, Ferrando, Adolfo A.
Published in Blood (08.12.2017)
Published in Blood (08.12.2017)
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Journal Article
Structure and Mechanisms of NT5C2 Mutations Driving Thiopurine Resistance in Relapsed Lymphoblastic Leukemia
Dieck, Chelsea L., Tzoneva, Gannie, Forouhar, Farhad, Carpenter, Zachary, Ambesi-Impiombato, Alberto, Sánchez-Martín, Marta, Kirschner-Schwabe, Renate, Lew, Scott, Seetharaman, Jayaraman, Tong, Liang, Ferrando, Adolfo A.
Published in Cancer cell (01.07.2018)
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Published in Cancer cell (01.07.2018)
Journal Article
Abstract PR02: Mechanisms of NT5C2 activating mutations driving thiopurine resistance in relapsed lymphoblastic leukemia
Dieck, Chelsea L., Tzoneva, Gannie, Forouhar, Farhad, Carpenter, Zachary, Sanchez-Martin, Marta, Ambesi-Impiombato, Alberto, Kirschner-Schwabe, Renate, Lew, Scott, Seetharaman, Jayaraman, Tong, Liang, Ferrando, Adolfo
Published in Clinical cancer research (15.12.2017)
Published in Clinical cancer research (15.12.2017)
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Journal Article
Clonal Evolution Mechanisms and Collateral Sensitivity to Impdh Inhibitor Therapy in Relapsed Lymphoblastic Leukemia
Dieck, Chelsea, Tzoneva, Gannie, Oshima, Koichi, Ambesi-Impiombato, Alberto, Sanchez-Martin, Marta, Sulis, Maria Luisa, Kato, Motohiro, Koh, Katsuyoshi, Paganin, Maddalena, Basso, Giuseppe, Gastier-Foster, Julie M., Loh, Mignon L., Kirschner-Schwabe, Renate, Madubata, Chioma, Rabadan, Raul, Ferrando, Adolfo A.
Published in Blood (08.12.2017)
Published in Blood (08.12.2017)
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Journal Article
Mutational Landscape, Clonal Evolution Patterns and Role of RAS Mutations in Relapsed Acute Lymphoblastic Leukemia
Oshima, Koichi, Khiabanian, Hossein, da Silva Almeida, Ana Carolina, Tzoneva, Gannie, Abate, Francesco, Ambesi-Impiombato, Alberto, Sanchez-Martin, Marta, Carpenter, Zachary, Penson, Alexander, Perez-Garcia, Arianne, Eckert, Cornelia, Nicolás, Concepción, Balbin, Milagros, Sulis, Maria Luisa, Kato, Motohiro, Koh, Katsuyoshi, Paganin, Maddalena, Basso, Giuseppe, Gastier-Foster, Julie M., Devidas, Meenakshi, Loh, Mignon L., Kirschner-Schwabe, Renate, Palomero, Teresa, Rabadan, Raul, Ferrando, Adolfo A.
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
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Journal Article
Abstract 4595: Activating mutations in the NT5C2 nucleotidase gene drive chemotherapy resistance in relapsed ALL
Tzoneva, Gannie, Perez-Garcia, Arianne, Carpenter, Zachary, Khiabanian, Hossein, Tosello, Valeria, Allegretta, Maddalena, Paietta, Elisabeth, Racevkis, Janis, Rowe, Jakob M., Tallman, Martin S., Paganin, Maddalena, Hoff, Jana, Kirschner-Schwabe, Renate, Palomero, Teresa, Rabadan, Raul, Ferrando, Adolfo
Published in Cancer research (Chicago, Ill.) (15.04.2013)
Published in Cancer research (Chicago, Ill.) (15.04.2013)
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Journal Article
Deregulated LAP2α expression in cervical cancer associates with aberrant E2F and p53 activities
Ward, Michelle C, van der Watt, Pauline J, Tzoneva, Gannie, Leaner, Virna D
Published in IUBMB life (01.11.2011)
Published in IUBMB life (01.11.2011)
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Journal Article
Genetic and functional evidence relates a missense variant in B4GALT1 to lower LDL-C and fibrinogen
Montasser, May E, Van Hout, Cristopher V, Mcfarland, Rebecca, Rosenberg, Avraham, Callaway, Myrasol, Shen, Biao, Li, Ning, Daly, Thomas J, Howard, Alicia D, Lin, Wei, Mao, Yuan, Ye, Bin, Giusy Della Gatta, Tzoneva, Gannie, Perry, James, Ryan, Kathleen A, Miloscio, Lawrence, Economides, Aris N, Center, Regeneron Genetics, Nhlbi Topmed Program, Sztalryd-Woodle, Carole, Mitchell, Braxton D, Healy, Matthew, Streeten, Elizabeth, Zaghloul, Norann A, Taylor, Simeon I, O'connell, Jeffrey R, Shuldiner, Alan R
Published in bioRxiv (01.08.2019)
Published in bioRxiv (01.08.2019)
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