The pharmacokinetics, CNS pharmacodynamics and adverse event profile of brivaracetam after single increasing oral doses in healthy males
Sargentini‐Maier, Maria Laura, Rolan, Paul, Connell, John, Tytgat, Dominique, Jacobs, Tom, Pigeolet, Etienne, Riethuisen, Jean‐Michel, Stockis, Armel
Published in British journal of clinical pharmacology (01.06.2007)
Published in British journal of clinical pharmacology (01.06.2007)
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Brivaracetam, a selective high‐affinity synaptic vesicle protein 2A (SV2A) ligand with preclinical evidence of high brain permeability and fast onset of action
Nicolas, Jean‐Marie, Hannestad, Jonas, Holden, Daniel, Kervyn, Sophie, Nabulsi, Nabeel, Tytgat, Dominique, Huang, Yiyun, Chanteux, Hugues, Staelens, Ludovicus, Matagne, Alain, Mathy, François‐Xavier, Mercier, Joël, Stockis, Armel, Carson, Richard E., Klitgaard, Henrik
Published in Epilepsia (Copenhagen) (01.02.2016)
Published in Epilepsia (Copenhagen) (01.02.2016)
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First-in-human studies of seletalisib, an orally bioavailable small-molecule PI3Kδ inhibitor for the treatment of immune and inflammatory diseases
Helmer, Eric, Watling, Mark, Jones, Emma, Tytgat, Dominique, Jones, Mark, Allen, Rodger, Payne, Andrew, Koch, Annelize, Healy, Eugene
Published in European journal of clinical pharmacology (01.05.2017)
Published in European journal of clinical pharmacology (01.05.2017)
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Adenosine 2A receptor occupancy by tozadenant and preladenant in rhesus monkeys
Barret, Olivier, Hannestad, Jonas, Alagille, David, Vala, Christine, Tavares, Adriana, Papin, Caroline, Morley, Thomas, Fowles, Krista, Lee, Hsiaoju, Seibyl, John, Tytgat, Dominique, Laruelle, Marc, Tamagnan, Gilles
Published in Journal of Nuclear Medicine (01.10.2014)
Published in Journal of Nuclear Medicine (01.10.2014)
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Effect of Rifampin on the Disposition of Brivaracetam in Human Subjects: Further Insights into Brivaracetam Hydrolysis
Stockis, Armel, Watanabe, Shikiko, Scheen, André J, Tytgat, Dominique, Gerin, Brigitte, Rosa, Maria, Chanteux, Hugues, Nicolas, Jean-Marie
Published in Drug metabolism and disposition (01.06.2016)
Published in Drug metabolism and disposition (01.06.2016)
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[ super(11)C]UCB-A, a novel PET tracer for synaptic vesicle protein 2 A
Estradaa, Sergio, Lubberinkb, Mark, Thibblinb, Alf, Sprychad, Margareta, Buchanane, Tim, Mestdaghe, Nathalie, Kendae, Benoit, Merciere, Joel, Provinse, Laurent, Gillarde, Michel, Tytgate, Dominique, Antonia, Gunnar
Published in Nuclear medicine and biology (01.06.2016)
Published in Nuclear medicine and biology (01.06.2016)
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Physiologically based pharmacokinetics (PBPK)
Espié, Pascal, Tytgat, Dominique, Sargentini-Maier, Maria-Laura, Poggesi, Italo, Watelet, Jean-Baptiste
Published in Drug metabolism reviews (01.08.2009)
Published in Drug metabolism reviews (01.08.2009)
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First-in-human studies of seletalisib, an orally bioavailable small-molecule PI3K[delta] inhibitor for the treatment of immune and inflammatory diseases
Helmer, Eric, Watling, Mark, Jones, Emma, Tytgat, Dominique, Jones, Mark, Allen, Rodger, Payne, Andrew, Koch, Annelize, Healy, Eugene
Published in European journal of clinical pharmacology (01.05.2017)
Published in European journal of clinical pharmacology (01.05.2017)
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[11C]UCB-A, a novel PET tracer for synaptic vesicle protein 2A
Estrada, Sergio, Lubberink, Mark, Thibblin, Alf, Sprycha, Margareta, Buchanan, Tim, Mestdagh, Nathalie, Kenda, Benoit, Mercier, Joel, Provins, Laurent, Gillard, Michel, Tytgat, Dominique, Antoni, Gunnar
Published in Nuclear medicine and biology (01.06.2016)
Published in Nuclear medicine and biology (01.06.2016)
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[11 C]UCB-A, a n3ovel PET tracer for synaptic vesicle protein 2A
Estrada, Sergio, Lubberink, Mark, Thibblin, Alf, Sprycha, Margareta, Buchanan, Tim, Mestdagh, Nathalie, Kenda, Benoit, Mercier, Joel, Provins, Laurent, Gillard, Michel, Tytgat, Dominique, Antoni, Gunnar
Published in Nuclear medicine and biology (2016)
Published in Nuclear medicine and biology (2016)
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Physiologically based pharmacokinetics (PBPK): Drug Metabolism and Disposition: Concepts and Applications in Allergic Diseases
ESPIE, Pascal, TYTGAT, Dominique, SARGENTINI-MAIER, Maria-Laura, POGGESI, Italo, WATELET, Jean-Baptiste
Published in Drug metabolism reviews (2009)
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Published in Drug metabolism reviews (2009)
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