Short-Course, High-Dose Rifampicin Achieves Wolbachia Depletion Predictive of Curative Outcomes in Preclinical Models of Lymphatic Filariasis and Onchocerciasis
Aljayyoussi, Ghaith, Tyrer, Hayley E., Ford, Louise, Sjoberg, Hanna, Pionnier, Nicolas, Waterhouse, David, Davies, Jill, Gamble, Joanne, Metuge, Haelly, Cook, Darren A. N., Steven, Andrew, Sharma, Raman, Guimaraes, Ana F., Clare, Rachel H., Cassidy, Andrew, Johnston, Kelly L., Myhill, Laura, Hayward, Laura, Wanji, Samuel, Turner, Joseph D., Taylor, Mark J., Ward, Stephen A.
Published in Scientific reports (16.03.2017)
Published in Scientific reports (16.03.2017)
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A mutation in Nischarin causes otitis media via LIMK1 and NF-κB pathways
Crompton, Michael, Purnell, Tom, Tyrer, Hayley E, Parker, Andrew, Ball, Greg, Hardisty-Hughes, Rachel E, Gale, Richard, Williams, Debbie, Dean, Charlotte H, Simon, Michelle M, Mallon, Ann-Marie, Wells, Sara, Bhutta, Mahmood F, Burton, Martin J, Tateossian, Hilda, Brown, Steve D M
Published in PLoS genetics (01.08.2017)
Published in PLoS genetics (01.08.2017)
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Transcript Analysis Reveals a Hypoxic Inflammatory Environment in Human Chronic Otitis Media With Effusion
Bhutta, Mahmood F, Lambie, Jane, Hobson, Lindsey, Williams, Debbie, Tyrer, Hayley E, Nicholson, George, Brown, Steve D M, Brown, Helen, Piccinelli, Chiara, Devailly, Guillaume, Ramsden, James, Cheeseman, Michael T
Published in Frontiers in genetics (21.02.2020)
Published in Frontiers in genetics (21.02.2020)
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murine macrofilaricide pre-clinical screening model for onchocerciasis and lymphatic filariasis
Halliday, Alice, Guimaraes, Ana F, Tyrer, Hayley E, Metuge, Haelly Mejane, Patrick, Chounna Ndongmo Winston, Arnaud, Kengne-Ouafo Jonas, Kwenti, Tayong Dizzle Bita, Forsbrook, George, Steven, Andrew, Cook, Darren, Enyong, Peter, Wanji, Samuel, Taylor, Mark J, Turner, Joseph D
Published in Parasites & vectors (24.10.2014)
Published in Parasites & vectors (24.10.2014)
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HIF-VEGF pathways are critical for chronic otitis media in Junbo and Jeff mouse mutants
Cheeseman, Michael T, Tyrer, Hayley E, Williams, Debbie, Hough, Tertius A, Pathak, Paras, Romero, Maria R, Hilton, Helen, Bali, Sulzhan, Parker, Andrew, Vizor, Lucie, Purnell, Tom, Vowell, Kate, Wells, Sara, Bhutta, Mahmood F, Potter, Paul K, Brown, Steve D M
Published in PLoS genetics (01.10.2011)
Published in PLoS genetics (01.10.2011)
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Author Correction: Short-Course, High-Dose Rifampicin Achieves Wolbachia Depletion Predictive of Curative Outcomes in Preclinical Models of Lymphatic Filariasis and Onchocerciasis
Aljayyoussi, Ghaith, Tyrer, Hayley E., Ford, Louise, Sjoberg, Hanna, Pionnier, Nicolas, Waterhouse, David, Davies, Jill, Gamble, Joanne, Metuge, Haelly, Cook, Darren A. N., Steven, Andrew, Sharma, Raman, Guimaraes, Ana F., Clare, Rachel H., Cassidy, Andrew, Johnston, Kelly L., Myhill, Laura, Hayward, Laura, Wanji, Samuel, Turner, Joseph D., Taylor, Mark J., Ward, Stephen A.
Published in Scientific reports (18.01.2018)
Published in Scientific reports (18.01.2018)
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A mouse model for osseous heteroplasia
Cheeseman, Michael T, Vowell, Kate, Hough, Tertius A, Jones, Lynn, Pathak, Paras, Tyrer, Hayley E, Kelly, Michelle, Cox, Roger, Warren, Madhuri V, Peters, Jo
Published in PloS one (19.12.2012)
Published in PloS one (19.12.2012)
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Preclinical development of an oral anti- Wolbachia macrolide drug for the treatment of lymphatic filariasis and onchocerciasis
Taylor, Mark J, von Geldern, Thomas W, Ford, Louise, Hübner, Marc P, Marsh, Kennan, Johnston, Kelly L, Sjoberg, Hanna T, Specht, Sabine, Pionnier, Nicolas, Tyrer, Hayley E, Clare, Rachel H, Cook, Darren A N, Murphy, Emma, Steven, Andrew, Archer, John, Bloemker, Dominique, Lenz, Franziska, Koschel, Marianne, Ehrens, Alexandra, Metuge, Haelly M, Chunda, Valerinne C, Ndongmo Chounna, Patrick W, Njouendou, Abdel J, Fombad, Fanny F, Carr, Robert, Morton, Howard E, Aljayyoussi, Ghaith, Hoerauf, Achim, Wanji, Samuel, Kempf, Dale J, Turner, Joseph D, Ward, Stephen A
Published in Science translational medicine (13.03.2019)
Published in Science translational medicine (13.03.2019)
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Albendazole and antibiotics synergize to deliver short-course anti-Wolbachia curative treatments in preclinical models of filariasis
Turner, Joseph D., Sharma, Raman, Al Jayoussi, Ghaith, Tyrer, Hayley E., Gamble, Joanne, Hayward, Laura, Priestley, Richard S., Murphy, Emma A., Davies, Jill, Waterhouse, David, Cook, Darren A. N., Clare, Rachel H., Cassidy, Andrew, Steven, Andrew, Johnston, Kelly L., McCall, John, Ford, Louise, Hemingway, Janet, Ward, Stephen A., Taylor, Mark J.
Published in Proceedings of the National Academy of Sciences - PNAS (07.11.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (07.11.2017)
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Minocycline as a re-purposed anti-Wolbachia macrofilaricide: superiority compared with doxycycline regimens in a murine infection model of human lymphatic filariasis
Sharma, Raman, Jayoussi, Ghaith Al, Tyrer, Hayley E., Gamble, Joanne, Hayward, Laura, Guimaraes, Ana F., Davies, Jill, Waterhouse, David, Cook, Darren A. N., Myhill, Laura J., Clare, Rachel H., Cassidy, Andrew, Steven, Andrew, Johnston, Kelly L., Ford, Louise, Turner, Joseph D., Ward, Stephen A., Taylor, Mark J.
Published in Scientific reports (21.03.2016)
Published in Scientific reports (21.03.2016)
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Journal Article
What Have We Learned from Murine Models of Otitis Media?
Tyrer, Hayley E., Crompton, Michael, Bhutta, Mahmood F.
Published in Current allergy and asthma reports (01.10.2013)
Published in Current allergy and asthma reports (01.10.2013)
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Journal Article
Corrigendum: Minocycline as a re-purposed anti-Wolbachia macrofilaricide: superiority compared with doxycycline regimens in a murine infection model of human lymphatic filariasis
Sharma, Raman, Aljayyoussi, Ghaith, Tyrer, Hayley E, Gamble, Joanne, Hayward, Laura, Guimaraes, Ana F, Davies, Jill, Waterhouse, David, Cook, Darren A N, Myhill, Laura J, Clare, Rachel H, Cassidy, Andrew, Steven, Andrew, Johnston, Kelly L, Ford, Louise, Turner, Joseph D, Ward, Stephen A, Taylor, Mark J
Published in Scientific reports (08.01.2018)
Published in Scientific reports (08.01.2018)
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Journal Article
What Have We Learned from Murine Models of Otitis Media?
Tyrer, Hayley E., Crompton, Michael, Bhutta, Mahmood F.
Published in Current allergy and asthma reports (01.10.2013)
Published in Current allergy and asthma reports (01.10.2013)
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Journal Article
A mutation in Nischarin causes otitis media via LIMK1 and NF-KB pathways
Crompton, Michael, Purnell, Tom, Tyrer, Hayley E, Parker, Andrew, Ball, Greg, Hardisty-Hughes, Rachel E, Gale, Richard, Williams, Debbie, Dean, Charlotte H, Simon, Michelle M, Mallon, Ann-Marie, Wells, Sara, Bhutta, Mahmood F, Burton, Martin J, Tateossian, Hilda, Brown, Steve D M
Published in PLoS genetics (01.08.2017)
Published in PLoS genetics (01.08.2017)
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Journal Article
Correction: Corrigendum: Minocycline as a re-purposed anti-Wolbachia macrofilaricide: superiority compared with doxycycline regimens in a murine infection model of human lymphatic filariasis
Sharma, Raman, Aljayyoussi, Ghaith, Tyrer, Hayley E., Gamble, Joanne, Hayward, Laura, Guimaraes, Ana F., Davies, Jill, Waterhouse, David, Cook, Darren A. N., Myhill, Laura J., Clare, Rachel H., Cassidy, Andrew, Steven, Andrew, Johnston, Kelly L., Ford, Louise, Turner, Joseph D., Ward, Stephen A., Taylor, Mark J.
Published in Scientific reports (08.01.2018)
Published in Scientific reports (08.01.2018)
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Journal Article
HIF-VEGF Pathways Are Critical for Chronic Otitis Media in Junbo and Jeff Mouse Mutants: e1002336
Cheeseman, Michael T, Tyrer, Hayley E, Williams, Debbie, Hough, Tertius A, Pathak, Paras, Romero, Maria R, Hilton, Helen, Bali, Sulzhan, Parker, Andrew, Vizor, Lucie, Purnell, Tom, Vowell, Kate, Wells, Sara, Bhutta, Mahmood F, Potter, Paul K, Brown, Steve DM
Published in PLoS genetics (01.10.2011)
Published in PLoS genetics (01.10.2011)
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