Stabilized gene duplication enables long-term selection-free heterologous pathway expression
Stephanopoulos, Gregory, Tyo, Keith E J, Ajikumar, Parayil Kumaran
Published in Nature biotechnology (01.08.2009)
Published in Nature biotechnology (01.08.2009)
Get full text
Journal Article
Pickaxe: a Python library for the prediction of novel metabolic reactions
Shebek, Kevin M, Strutz, Jonathan, Broadbelt, Linda J, Tyo, Keith E J
Published in BMC bioinformatics (22.03.2023)
Published in BMC bioinformatics (22.03.2023)
Get full text
Journal Article
Bayesian inference of metabolic kinetics from genome-scale multiomics data
St John, Peter C, Strutz, Jonathan, Broadbelt, Linda J, Tyo, Keith E J, Bomble, Yannick J
Published in PLoS computational biology (04.11.2019)
Published in PLoS computational biology (04.11.2019)
Get full text
Journal Article
Recording Temporal Signals with Minutes Resolution Using Enzymatic DNA Synthesis
Bhan, Namita, Callisto, Alec, Strutz, Jonathan, Glaser, Joshua, Kalhor, Reza, Boyden, Edward S, Church, George, Kording, Konrad, Tyo, Keith E. J
Published in Journal of the American Chemical Society (13.10.2021)
Published in Journal of the American Chemical Society (13.10.2021)
Get full text
Journal Article
MINE 2.0: enhanced biochemical coverage for peak identification in untargeted metabolomics
Strutz, Jonathan, Shebek, Kevin M, Broadbelt, Linda J, Tyo, Keith E J
Published in Bioinformatics (27.06.2022)
Published in Bioinformatics (27.06.2022)
Get full text
Journal Article
MINEs: open access databases of computationally predicted enzyme promiscuity products for untargeted metabolomics
Jeffryes, James G, Colastani, Ricardo L, Elbadawi-Sidhu, Mona, Kind, Tobias, Niehaus, Thomas D, Broadbelt, Linda J, Hanson, Andrew D, Fiehn, Oliver, Tyo, Keith E J, Henry, Christopher S
Published in Journal of cheminformatics (28.08.2015)
Published in Journal of cheminformatics (28.08.2015)
Get full text
Journal Article
Isoprenoid Pathway Optimization for Taxol Precursor Overproduction in Escherichia coli
Ajikumar, Parayil Kumaran, Xiao, Wen-Hai, Tyo, Keith E. J., Wang, Yong, Simeon, Fritz, Leonard, Effendi, Mucha, Oliver, Phon, Too Heng, Pfeifer, Blaine, Stephanopoulos, Gregory
Published in Science (American Association for the Advancement of Science) (01.10.2010)
Published in Science (American Association for the Advancement of Science) (01.10.2010)
Get full text
Journal Article
Stepping on the Gas to a Circular Economy: Accelerating Development of Carbon-Negative Chemical Production from Gas Fermentation
Fackler, Nick, Heijstra, Björn D, Rasor, Blake J, Brown, Hunter, Martin, Jacob, Ni, Zhuofu, Shebek, Kevin M, Rosin, Rick R, Simpson, Séan D, Tyo, Keith E, Giannone, Richard J, Hettich, Robert L, Tschaplinski, Timothy J, Leang, Ching, Brown, Steven D, Jewett, Michael C, Köpke, Michael
Published in Annual review of chemical and biomolecular engineering (07.06.2021)
Published in Annual review of chemical and biomolecular engineering (07.06.2021)
Get full text
Journal Article
Development of a genetic toolset for the highly engineerable and metabolically versatile Acinetobacter baylyi ADP1
Biggs, Bradley W, Bedore, Stacy R, Arvay, Erika, Huang, Shu, Subramanian, Harshith, McIntyre, Emily A, Duscent-Maitland, Chantel V, Neidle, Ellen L, Tyo, Keith E J
Published in Nucleic acids research (21.05.2020)
Published in Nucleic acids research (21.05.2020)
Get full text
Journal Article
Expanding the metabolic engineering toolbox: more options to engineer cells
Tyo, Keith E, Alper, Hal S, Stephanopoulos, Gregory N
Published in Trends in biotechnology (Regular ed.) (01.03.2007)
Published in Trends in biotechnology (Regular ed.) (01.03.2007)
Get full text
Journal Article
Atomically precise (catalytic) particles synthesized by a novel cluster deposition instrument
Yin, C, Tyo, E, Kuchta, K, von Issendorff, B, Vajda, S
Published in The Journal of chemical physics (07.05.2014)
Published in The Journal of chemical physics (07.05.2014)
Get more information
Journal Article
Model-guided mechanism discovery and parameter selection for directed evolution
Stainbrook, Sarah C., Tyo, Keith E. J.
Published in Applied microbiology and biotechnology (01.12.2019)
Published in Applied microbiology and biotechnology (01.12.2019)
Get full text
Journal Article
N-Terminal-Based Targeted, Inducible Protein Degradation in Escherichia coli
Sekar, Karthik, Gentile, Andrew M, Bostick, John W, Tyo, Keith E J
Published in PloS one (22.02.2016)
Published in PloS one (22.02.2016)
Get full text
Journal Article
Impact of protein uptake and degradation on recombinant protein secretion in yeast
Tyo, Keith E. J, Liu, Zihe, Magnusson, Ylva, Petranovic, Dina, Nielsen, Jens
Published in Applied microbiology and biotechnology (01.08.2014)
Published in Applied microbiology and biotechnology (01.08.2014)
Get full text
Journal Article
High-resolution mapping of DNA polymerase fidelity using nucleotide imbalances and next-generation sequencing
de Paz, Alexandra M, Cybulski, Thaddeus R, Marblestone, Adam H, Zamft, Bradley M, Church, George M, Boyden, Edward S, Kording, Konrad P, Tyo, Keith E J
Published in Nucleic acids research (27.07.2018)
Published in Nucleic acids research (27.07.2018)
Get full text
Journal Article
Detection of a Peptide Biomarker by Engineered Yeast Receptors
Adeniran, Adebola, Stainbrook, Sarah, Bostick, John W, Tyo, Keith E. J
Published in ACS synthetic biology (16.02.2018)
Published in ACS synthetic biology (16.02.2018)
Get full text
Journal Article
Efficient searching and annotation of metabolic networks using chemical similarity
Pertusi, Dante A, Stine, Andrew E, Broadbelt, Linda J, Tyo, Keith E J
Published in Bioinformatics (01.04.2015)
Published in Bioinformatics (01.04.2015)
Get full text
Journal Article