Clinical validation of a noninvasive prenatal test for genomewide detection of fetal copy number variants
Lefkowitz, Roy B., PhD, Tynan, John A., PhD, Liu, Tong, PhD, Wu, Yijin, PhD, Mazloom, Amin R., PhD, Almasri, Eyad, MS, Hogg, Grant, MS, Angkachatchai, Vach, PhD, Zhao, Chen, PhD, Grosu, Daniel S., MD, McLennan, Graham, MS, Ehrich, Mathias, MD
Published in American journal of obstetrics and gynecology (01.08.2016)
Published in American journal of obstetrics and gynecology (01.08.2016)
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Journal Article
Noninvasive detection of fetal trisomy 21 by sequencing of DNA in maternal blood: a study in a clinical setting
Ehrich, Mathias, MD, Deciu, Cosmin, MSc, Zwiefelhofer, Tricia, Tynan, John A., DPhil, Cagasan, Lesley, MSc, Tim, Roger, DPhil, Lu, Vivian, McCullough, Ron, DPhil, McCarthy, Erin, Nygren, Anders O.H., DPhil, Dean, Jarrod, Tang, Lin, DPhil, Hutchison, Don, MSc, Lu, Tim, DPhil, Wang, Huiquan, DPhil, Angkachatchai, Vach, DPhil, Oeth, Paul, MSc, Cantor, Charles R., DPhil, Bombard, Allan, MD, van den Boom, Dirk, DPhil
Published in American journal of obstetrics and gynecology (01.03.2011)
Published in American journal of obstetrics and gynecology (01.03.2011)
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Journal Article
Multiplexed analysis of circulating cell-free fetal nucleic acids for noninvasive prenatal diagnostic RHD testing
Tynan, John A., DPhil, Angkachatchai, Vach, DPhil, Ehrich, Mathias, MD, Paladino, Toni, DPhil, van den Boom, Dirk, DPhil, Oeth, Paul, MS
Published in American journal of obstetrics and gynecology (01.03.2011)
Published in American journal of obstetrics and gynecology (01.03.2011)
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Journal Article
Horizons in Veterinary Precision Oncology: Fundamentals of Cancer Genomics and Applications of Liquid Biopsy for the Detection, Characterization, and Management of Cancer in Dogs
Chibuk, Jason, Flory, Andi, Kruglyak, Kristina M, Leibman, Nicole, Nahama, Alexis, Dharajiya, Nilesh, van den Boom, Dirk, Jensen, Taylor J, Friedman, Jeffrey S, Shen, M Richard, Clemente-Vicario, Francisco, Chorny, Ilya, Tynan, John A, Lytle, Katherine M, Holtvoigt, Lauren E, Murtaza, Muhammed, Diaz, Jr, Luis A, Tsui, Dana W Y, Grosu, Daniel S
Published in Frontiers in veterinary science (23.03.2021)
Published in Frontiers in veterinary science (23.03.2021)
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Journal Article
Ets2 is required for trophoblast stem cell self-renewal
Wen, Fang, Tynan, John A., Cecena, Grace, Williams, Roy, Múnera, Jorge, Mavrothalassitis, George, Oshima, Robert G.
Published in Developmental biology (01.12.2007)
Published in Developmental biology (01.12.2007)
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Journal Article
Blood-Based Liquid Biopsy for Comprehensive Cancer Genomic Profiling Using Next-Generation Sequencing: An Emerging Paradigm for Non-invasive Cancer Detection and Management in Dogs
Kruglyak, Kristina M, Chibuk, Jason, McLennan, Lisa, Nakashe, Prachi, Hernandez, Gilberto E, Motalli-Pepio, Rita, Fath, Donna M, Tynan, John A, Holtvoigt, Lauren E, Chorny, Ilya, Grosu, Daniel S, Tsui, Dana W Y, Flory, Andi
Published in Frontiers in veterinary science (08.07.2021)
Published in Frontiers in veterinary science (08.07.2021)
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Journal Article
Detection of Age-Related Somatic Alterations in Canine Blood Using Next-Generation Sequencing-Based Liquid Biopsy: An Analysis of over 4800 Dogs
Kruglyak, Kristina M, O'Kell, Allison L, Cohen, Todd A, Marshall, Maggie A, Ruiz-Perez, Carlos A, Marass, Francesco, Tynan, John A, Hicks, Susan C, Lytle, Katherine M, Phelps-Dunn, Ashley, Brandstetter, Gina, Warren, Chelsea D, DiMarzio, Lauren R, Rosentel, Michelle C, Wong, Lilian K, McLennan, Lisa M, Rafalko, Jill M, Grosu, Daniel S, Chibuk, Jason, Chorny, Ilya, McCleary-Wheeler, Angela L, Flory, Andi, Tsui, Dana W Y
Published in Veterinary sciences (01.07.2023)
Published in Veterinary sciences (01.07.2023)
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Journal Article
Transformation and Stat activation by derivatives of FGFR1, FGFR3, and FGFR4
HART, K. C, ROBERTSON, S. C, KANEMITSU, M. Y, MEYER, A. N, TYNAN, J. A, DONOGHUE, D. J
Published in Oncogene (06.07.2000)
Published in Oncogene (06.07.2000)
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Journal Article
Rotational coupling of the transmembrane and kinase domains of the Neu receptor tyrosine kinase
Bell, C A, Tynan, J A, Hart, K C, Meyer, A N, Robertson, S C, Donoghue, D J
Published in Molecular biology of the cell (01.10.2000)
Published in Molecular biology of the cell (01.10.2000)
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Journal Article
Clinical validation of a blood-based liquid biopsy test integrating cell-free DNA quantification and next-generation sequencing for cancer screening in dogs
Flory, Andi, Ruiz-Perez, Carlos A, Clavere-Graciette, Ana G, Rafalko, Jill M, O'Kell, Allison L, Flesner, Brian K, McLennan, Lisa M, Hicks, Susan C, Nakashe, Prachi, Phelps-Dunn, Ashley, DiMarzio, Lauren R, Warren, Chelsea D, Cohen, Todd A, Chibuk, Jason, Chorny, Ilya, Grosu, Daniel S, Tsui, Dana W Y, Tynan, John A, Kruglyak, Kristina M
Published in Journal of the American Veterinary Medical Association (01.05.2024)
Published in Journal of the American Veterinary Medical Association (01.05.2024)
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Journal Article
Next-generation sequencing-based liquid biopsy may be used for detection of residual disease and cancer recurrence monitoring in dogs
McCleary-Wheeler, Angela L, Fiaux, Patrick C, Flesner, Brian K, Ruiz-Perez, Carlos A, McLennan, Lisa M, Tynan, John A, Hicks, Susan C, Rafalko, Jill M, Grosu, Daniel S, Chibuk, Jason, O'Kell, Allison L, Cohen, Todd A, Chorny, Ilya, Tsui, Dana W Y, Kruglyak, Kristina M, Flory, Andi
Published in American journal of veterinary research (28.12.2023)
Published in American journal of veterinary research (28.12.2023)
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Journal Article
Clinical experience with next-generation sequencing-based liquid biopsy testing for cancer detection in dogs: a review of 1,500 consecutive clinical cases
O'Kell, Allison L, Lytle, Katherine M, Cohen, Todd A, Wong, Lilian K, Sandford, Emily, Rafalko, Jill M, Brandstetter, Gina, DiMarzio, Lauren R, Phelps-Dunn, Ashley, Rosentel, Michelle C, Warren, Chelsea D, McCleary-Wheeler, Angela L, Fiaux, Patrick C, Marass, Francesco, Marshall, Maggie A, Ruiz-Perez, Carlos A, Kruglyak, Kristina M, Tynan, John A, Hicks, Susan C, Grosu, Daniel S, Chibuk, Jason, Chorny, Ilya, Tsui, Dana W Y, Flory, Andi
Published in Journal of the American Veterinary Medical Association (01.06.2023)
Published in Journal of the American Veterinary Medical Association (01.06.2023)
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Journal Article
Proof-of-concept evaluation of next-generation sequencing-based liquid biopsy for non-invasive cancer detection in cats
Ruiz-Perez, Carlos A., Nakashe, Prachi, Marshall, Maggie A., Marass, Francesco, Tang, Tuong, McLennan, Lisa M., Kroll, Marissa, Flesner, Brian K., Gray, Suzanne, Rafalko, Jill M., Grosu, Daniel S., Hicks, Susan C., Tynan, John A., Tsui, Dana W.Y., Flory, Andi, Kruglyak, Kristina M.
Published in Frontiers in veterinary science (13.09.2024)
Published in Frontiers in veterinary science (13.09.2024)
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Journal Article
Ets2-Dependent Stromal Regulation of Mouse Mammary Tumors
Man, Albert K., Young, Lawrence J. T., Tynan, John A., Lesperance, Jacqueline, Egeblad, Mikala, Werb, Zena, Hauser, Craig A., Muller, William J., Cardiff, Robert D., Oshima, Robert G.
Published in Molecular and Cellular Biology (01.12.2003)
Published in Molecular and Cellular Biology (01.12.2003)
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Journal Article
RTK mutations and human syndromes: when good receptors turn bad
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Book Review
Journal Article
Human Speedy: A Novel Cell Cycle Regulator That Enhances Proliferation through Activation of Cdk2
Porter, Lisa A., Dellinger, Ryan W., Tynan, John A., Barnes, Elizabeth A., Kong, Monica, Lenormand, Jean-Luc, Donoghue, Daniel J.
Published in The Journal of cell biology (29.04.2002)
Published in The Journal of cell biology (29.04.2002)
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Journal Article
Analysis of Liquid Biopsy Performance for the Detection of Lymphoma in Dogs with a Focus on Recurrent Copy Number Variants in Matched Plasma and Lymph Node Aspirates: Implications for a Comparative Oncology Model
Chorny, Ilya, McCleary-Wheeler, Angela L, Flory, Andi, Kruglyak, Kristina M, Rafalko, Jill M, Grosu, Daniel S, O'Kell, Allison L, Cohen, Todd A, Chibuk, Jason, Hicks, Susan C, Tynan, John A, Tsui, Dana WY
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
Comparative oncology analysis using genomic profiling of canine cancers by tissue and liquid biopsy testing reveals actionable somatic alterations with orthologs in human cancers
Tsui, Dana, Chorny, Ilya, Kruglyak, Kristina M, Tynan, John A., Hernandez, Gilberto E, Nakashe, Prachi, Hicks, Susan Cho, Motalli-Pepio, Rita, McLennan, Lisa M., Holtvoigt, Lauren E., Rafalko, Jill M., Chibuk, Jason, McCleary-Wheeler, Angela L., Flory, Andi, Grosu, Daniel S.
Published in Journal of clinical oncology (01.06.2022)
Published in Journal of clinical oncology (01.06.2022)
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Journal Article