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Ho, Jemima, Yang, Xuexin, Nikou, Spyridoula-Angeliki, Kichik, Nessim, Donkin, Andrew, Ponde, Nicole O, Richardson, Jonathan P, Gratacap, Remi L, Archambault, Linda S, Zwirner, Christian P, Murciano, Celia, Henley-Smith, Rhonda, Thavaraj, Selvam, Tynan, Christopher J, Gaffen, Sarah L, Hube, Bernhard, Wheeler, Robert T, Moyes, David L, Naglik, Julian R
Published in Nature communications (24.05.2019)
Published in Nature communications (24.05.2019)
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EGFR oligomerization organizes kinase-active dimers into competent signalling platforms
Needham, Sarah R, Roberts, Selene K, Arkhipov, Anton, Mysore, Venkatesh P, Tynan, Christopher J, Zanetti-Domingues, Laura C, Kim, Eric T, Losasso, Valeria, Korovesis, Dimitrios, Hirsch, Michael, Rolfe, Daniel J, Clarke, David T, Winn, Martyn D, Lajevardipour, Alireza, Clayton, Andrew H A, Pike, Linda J, Perani, Michela, Parker, Peter J, Shan, Yibing, Shaw, David E, Martin-Fernandez, Marisa L
Published in Nature communications (31.10.2016)
Published in Nature communications (31.10.2016)
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The guidance and adhesion protein FLRT2 dimerizes in cis via dual small-X3-small transmembrane motifs
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Published in Structure (London) (01.09.2022)
Published in Structure (London) (01.09.2022)
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3D visualization of additive occlusion and tunable full-spectrum fluorescence in calcite
Green, David C, Ihli, Johannes, Thornton, Paul D, Holden, Mark A, Marzec, Bartosz, Kim, Yi-Yeoun, Kulak, Alex N, Levenstein, Mark A, Tang, Chiu, Lynch, Christophe, Webb, Stephen E D, Tynan, Christopher J, Meldrum, Fiona C
Published in Nature communications (18.11.2016)
Published in Nature communications (18.11.2016)
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The guidance and adhesion protein FLRT2 dimerizes in cis via dual small-X 3 -small transmembrane motifs
Jackson, Verity, Hermann, Julia, Tynan, Christopher J, Rolfe, Daniel J, Corey, Robin A, Duncan, Anna L, Noriega, Maxime, Chu, Amy, Kalli, Antreas C, Jones, E Yvonne, Sansom, Mark S P, Martin-Fernandez, Marisa L, Seiradake, Elena, Chavent, Matthieu
Published in Structure (London) (01.09.2022)
Published in Structure (London) (01.09.2022)
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Focal adhesions are sites of integrin extension
Askari, Janet A, Tynan, Christopher J, Webb, Stephen E.D, Martin-Fernandez, Marisa L, Ballestrem, Christoph, Humphries, Martin J
Published in The Journal of cell biology (22.03.2010)
Published in The Journal of cell biology (22.03.2010)
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AR cooperates with SMAD4 to maintain skeletal muscle homeostasis
Forouhan, Mitra, Lim, Wooi Fang, Zanetti-Domingues, Laura C., Tynan, Christopher J., Roberts, Thomas C., Malik, Bilal, Manzano, Raquel, Speciale, Alfina A., Ellerington, Ruth, Garcia-Guerra, Antonio, Fratta, Pietro, Sorarú, Gianni, Greensmith, Linda, Pennuto, Maria, Wood, Matthew J. A., Rinaldi, Carlo
Published in Acta neuropathologica (01.06.2022)
Published in Acta neuropathologica (01.06.2022)
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Supramolecular clustering of the cardiac sodium channel Nav1.5 in HEK293F cells, with and without the auxiliary β3‐subunit
Salvage, Samantha C., Rees, Johanna S., McStea, Alexandra, Hirsch, Michael, Wang, Lin, Tynan, Christopher J., Reed, Matthew W., Irons, Jennifer R., Butler, Richard, Thompson, Andrew J., Martin-Fernandez, Marisa L., Huang, Christopher L.‐H., Jackson, Antony P.
Published in The FASEB journal (01.03.2020)
Published in The FASEB journal (01.03.2020)
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Multicolour single molecule imaging in cells with near infra-red dyes
Tynan, Christopher J, Clarke, David T, Coles, Benjamin C, Rolfe, Daniel J, Martin-Fernandez, Marisa L, Webb, Stephen E D
Published in PloS one (25.04.2012)
Published in PloS one (25.04.2012)
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Structure-function relationships and supramolecular organization of the EGFR (epidermal growth factor receptor) on the cell surface
Needham, Sarah R, Zanetti-Domingues, Laura C, Hirsch, Michael, Rolfe, Daniel J, Tynan, Christopher J, Roberts, Selene K, Martin-Fernandez, Marisa L, Clarke, David T
Published in Biochemical Society transactions (01.02.2014)
Published in Biochemical Society transactions (01.02.2014)
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Human Epidermal Growth Factor Receptor (EGFR) Aligned on the Plasma Membrane Adopts Key Features of Drosophila EGFR Asymmetry
Tynan, Christopher J., Roberts, Selene K., Rolfe, Daniel J., Clarke, David T., Loeffler, Hannes H., Kästner, Johannes, Winn, Martyn D., Parker, Peter J., Martin-Fernandez, Marisa L.
Published in Molecular and Cellular Biology (01.06.2011)
Published in Molecular and Cellular Biology (01.06.2011)
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A tale of the epidermal growth factor receptor: The quest for structural resolution on cells
Tynan, Christopher J., Lo Schiavo, Valentina, Zanetti-Domingues, Laura, Needham, Sarah R., Roberts, Selene K., Hirsch, Michael, Rolfe, Daniel J., Korovesis, Dimitrios, Clarke, David T., Martin-Fernandez, Marisa L.
Published in Methods (San Diego, Calif.) (15.02.2016)
Published in Methods (San Diego, Calif.) (15.02.2016)
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Determining the geometry of oligomers of the human epidermal growth factor family on cells with <10 nm resolution
Needham, Sarah R, Zanetti-Domingues, Laura C, Scherer, Kathrin M, Hirsch, Michael, Rolfe, Daniel J, Roberts, Selene K, Martin-Fernandez, Marisa L, Clarke, David T, Tynan, Christopher J
Published in Biochemical Society transactions (01.06.2015)
Published in Biochemical Society transactions (01.06.2015)
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Nanometric molecular separation measurements by single molecule photobleaching
Webb, Stephen E.D., Hirsch, Michael, Needham, Sarah R., Coles, Benjamin C., Scherer, Kathrin M., Roberts, Selene K., Zanetti-Domingues, Laura C., Tynan, Christopher J., Martin-Fernandez, Marisa L., Rolfe, Daniel J.
Published in Methods (San Diego, Calif.) (15.10.2015)
Published in Methods (San Diego, Calif.) (15.10.2015)
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Single-Molecule Imaging and Fluorescence Lifetime Imaging Microscopy Show Different Structures for High- and Low-Affinity Epidermal Growth Factor Receptors in A431 Cells
Webb, Stephen E.D., Roberts, Selene K., Needham, Sarah R., Tynan, Christopher J., Rolfe, Daniel J., Winn, Martyn D., Clarke, David T., Barraclough, Roger, Martin-Fernandez, Marisa L.
Published in Biophysical journal (01.02.2008)
Published in Biophysical journal (01.02.2008)
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Self-association of Calcium-binding Protein S100A4 and Metastasis
Ismail, Thamir M., Zhang, Shu, Fernig, David G., Gross, Stephane, Martin-Fernandez, Marisa L., See, Violaine, Tozawa, Kaeko, Tynan, Christopher J., Wang, Guozheng, Wilkinson, Mark C., Rudland, Philip S., Barraclough, Roger
Published in The Journal of biological chemistry (08.01.2010)
Published in The Journal of biological chemistry (08.01.2010)
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The architecture of EGFR's basal complexes reveals autoinhibition mechanisms in dimers and oligomers
Zanetti-Domingues, Laura C, Korovesis, Dimitrios, Needham, Sarah R, Tynan, Christopher J, Sagawa, Shiori, Roberts, Selene K, Kuzmanic, Antonija, Ortiz-Zapater, Elena, Jain, Purvi, Roovers, Rob C, Lajevardipour, Alireza, van Bergen En Henegouwen, Paul M P, Santis, George, Clayton, Andrew H A, Clarke, David T, Gervasio, Francesco L, Shan, Yibing, Shaw, David E, Rolfe, Daniel J, Parker, Peter J, Martin-Fernandez, Marisa L
Published in Nature communications (18.10.2018)
Published in Nature communications (18.10.2018)
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Determining the geometry of oligomers of the human epidermal growth factor family on cells with 7 nm resolution
Zanetti-Domingues, Laura C., Hirsch, Michael, Tynan, Christopher J., Rolfe, Daniel J., Boyadzhiev, Teodor V., Scherer, Kathrin M., Clarke, David T., Martin-Fernandez, Marisa L., Needham, Sarah R.
Published in Progress in biophysics and molecular biology (01.09.2015)
Published in Progress in biophysics and molecular biology (01.09.2015)
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