The SYK tyrosine kinase: a crucial player in diverse biological functions
Mócsai, Attila, Ruland, Jürgen, Tybulewicz, Victor L. J
Published in Nature reviews. Immunology (01.06.2010)
Published in Nature reviews. Immunology (01.06.2010)
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Journal Article
A genetic cause of Alzheimer disease: mechanistic insights from Down syndrome
Wiseman, Frances K, Al-Janabi, Tamara, Hardy, John, Karmiloff-Smith, Annette, Nizetic, Dean, Tybulewicz, Victor L J, Fisher, Elizabeth M C, Strydom, André
Published in Nature reviews. Neuroscience (01.09.2015)
Published in Nature reviews. Neuroscience (01.09.2015)
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Journal Article
Association of Dementia With Mortality Among Adults With Down Syndrome Older Than 35 Years
Hithersay, Rosalyn, Startin, Carla M, Hamburg, Sarah, Mok, Kin Y, Hardy, John, Fisher, Elizabeth M C, Tybulewicz, Victor L J, Nizetic, Dean, Strydom, André
Published in Archives of neurology (Chicago) (01.02.2019)
Published in Archives of neurology (Chicago) (01.02.2019)
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Journal Article
Chloride sensing by WNK1 regulates NLRP3 inflammasome activation and pyroptosis
Mayes-Hopfinger, Lindsey, Enache, Aura, Xie, Jian, Huang, Chou-Long, Köchl, Robert, Tybulewicz, Victor L J, Fernandes-Alnemri, Teresa, Alnemri, Emad S
Published in Nature communications (27.07.2021)
Published in Nature communications (27.07.2021)
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Journal Article
The BAFF Receptor Transduces Survival Signals by Co-opting the B Cell Receptor Signaling Pathway
Schweighoffer, Edina, Vanes, Lesley, Nys, Josquin, Cantrell, Doreen, McCleary, Scott, Smithers, Nicholas, Tybulewicz, Victor L.J.
Published in Immunity (Cambridge, Mass.) (21.03.2013)
Published in Immunity (Cambridge, Mass.) (21.03.2013)
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Journal Article
Down syndrome—recent progress and future prospects
Wiseman, Frances K., Alford, Kate A., Tybulewicz, Victor L.J., Fisher, Elizabeth M.C.
Published in Human molecular genetics (15.04.2009)
Published in Human molecular genetics (15.04.2009)
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Journal Article
T cell migration requires ion and water influx to regulate actin polymerization
de Boer, Leonard L, Vanes, Lesley, Melgrati, Serena, Biggs O'May, Joshua, Hayward, Darryl, Driscoll, Paul C, Day, Jason, Griffiths, Alexander, Magueta, Renata, Morrell, Alexander, MacRae, James I, Köchl, Robert, Tybulewicz, Victor L J
Published in Nature communications (06.12.2023)
Published in Nature communications (06.12.2023)
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Journal Article
Species-Specific Transcription in Mice Carrying Human Chromosome 21
Wilson, Michael D, Barbosa-Morais, Nuno L, Schmidt, Dominic, Conboy, Caitlin M, Vanes, Lesley, Tybulewicz, Victor L.J, Fisher, Elizabeth M.C, Tavaré, Simon, Odom, Duncan T
Published in Science (American Association for the Advancement of Science) (17.10.2008)
Published in Science (American Association for the Advancement of Science) (17.10.2008)
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Journal Article
Long noncoding RNAs in B-cell development and activation
Brazão, Tiago F., Johnson, Jethro S., Müller, Jennifer, Heger, Andreas, Ponting, Chris P., Tybulewicz, Victor L.J.
Published in Blood (18.08.2016)
Published in Blood (18.08.2016)
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Journal Article
CLEC-2 and Syk in the megakaryocytic/platelet lineage are essential for development
Finney, Brenda A., Schweighoffer, Edina, Navarro-Núñez, Leyre, Bénézech, Cecile, Barone, Francesca, Hughes, Craig E., Langan, Stacey A., Lowe, Kate L., Pollitt, Alice Y., Mourao-Sa, Diego, Sheardown, Steve, Nash, Gerard B., Smithers, Nicholas, Reis e Sousa, Caetano, Tybulewicz, Victor L.J., Watson, Steve P.
Published in Blood (16.02.2012)
Published in Blood (16.02.2012)
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Journal Article
Affordable optical clearing and immunolabelling in mouse brain slices
Muza, Phillip M, Pérez, Marta, Noy, Suzanna, Kurosawa, Miyu, Katsouri, Loukia, Tybulewicz, Victor L. J, Fisher, Elizabeth M.C, West, Steven J
Published in BMC research notes (30.09.2023)
Published in BMC research notes (30.09.2023)
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Journal Article
Gene expression dysregulation domains are not a specific feature of Down syndrome
Ahlfors, Helena, Anyanwu, Nneka, Pakanavicius, Edvinas, Dinischiotu, Natalia, Lana-Elola, Eva, Watson-Scales, Sheona, Tosh, Justin, Wiseman, Frances, Briscoe, James, Page, Karen, Fisher, Elizabeth M C, Tybulewicz, Victor L J
Published in Nature communications (06.06.2019)
Published in Nature communications (06.06.2019)
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Journal Article
Rodent models in Down syndrome research: impact and future opportunities
Herault, Yann, Delabar, Jean M, Fisher, Elizabeth M C, Tybulewicz, Victor L J, Yu, Eugene, Brault, Veronique
Published in Disease models & mechanisms (01.10.2017)
Published in Disease models & mechanisms (01.10.2017)
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Journal Article
Analysis of motor dysfunction in Down Syndrome reveals motor neuron degeneration
Watson-Scales, Sheona, Kalmar, Bernadett, Lana-Elola, Eva, Gibbins, Dorota, La Russa, Federica, Wiseman, Frances, Williamson, Matthew, Saccon, Rachele, Slender, Amy, Olerinyova, Anna, Mahmood, Radma, Nye, Emma, Cater, Heather, Wells, Sara, Yu, Y Eugene, Bennett, David L H, Greensmith, Linda, Fisher, Elizabeth M C, Tybulewicz, Victor L J
Published in PLoS genetics (10.05.2018)
Published in PLoS genetics (10.05.2018)
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Journal Article
Aneuploid Mouse Strain Carrying Human Chromosome 21 with Down Syndrome Phenotypes
O'Doherty, Aideen, Ruf, Sandra, Mulligan, Claire, Hildreth, Victoria, Errington, Mick L, Cooke, Sam, Sesay, Abdul, Modino, Sonie, Vanes, Lesley, Hernandez, Diana, Linehan, Jacqueline M, Sharpe, Paul T, Brandner, Sebastian, Bliss, Timothy V. P, Henderson, Deborah J, Nizetic, Dean, Tybulewicz, Victor L. J, Fisher, Elizabeth M. C
Published in Science (American Association for the Advancement of Science) (23.09.2005)
Published in Science (American Association for the Advancement of Science) (23.09.2005)
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Journal Article
Genetic dissection of down syndrome-associated alterations in APP/amyloid-β biology using mouse models
Tosh, Justin L, Rhymes, Elena R, Mumford, Paige, Whittaker, Heather T, Pulford, Laura J, Noy, Sue J, Cleverley, Karen, Walker, Matthew C, Tybulewicz, Victor L J, Wykes, Rob C, Fisher, Elizabeth M C, Wiseman, Frances K
Published in Scientific reports (11.03.2021)
Published in Scientific reports (11.03.2021)
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Journal Article
Activation of the Small GTPase Rac2 via the B Cell Receptor Regulates B Cell Adhesion and Immunological-Synapse Formation
Arana, Eloisa, Vehlow, Anne, Harwood, Naomi E., Vigorito, Elena, Henderson, Robert, Turner, Martin, Tybulewicz, Victor L.J., Batista, Facundo D.
Published in Immunity (Cambridge, Mass.) (01.01.2008)
Published in Immunity (Cambridge, Mass.) (01.01.2008)
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Journal Article