A hydrogen borrowing annulation strategy for the stereocontrolled synthesis of saturated aza-heterocycles
Chamberlain, Anna E. R., Paterson, Kieran J., Armstrong, Roly J., Twin, Heather C., Donohoe, Timothy J.
Published in Chemical communications (Cambridge, England) (25.03.2020)
Published in Chemical communications (Cambridge, England) (25.03.2020)
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Design and Optimization of Selective Protein Kinase C θ (PKCθ) Inhibitors for the Treatment of Autoimmune Diseases
Jimenez, Juan-Miguel, Boyall, Dean, Brenchley, Guy, Collier, Philip N, Davis, Christopher J, Fraysse, Damien, Keily, Shazia B, Henderson, Jaclyn, Miller, Andrew, Pierard, Francoise, Settimo, Luca, Twin, Heather C, Bolton, Claire M, Curnock, Adam P, Chiu, Peter, Tanner, Adam J, Young, Stephen
Published in Journal of medicinal chemistry (14.03.2013)
Published in Journal of medicinal chemistry (14.03.2013)
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Discovery of Selective, Orally Bioavailable Pyrazolopyridine Inhibitors of Protein Kinase Cθ (PKCθ) That Ameliorate Symptoms of Experimental Autoimmune Encephalomyelitis
Collier, Philip N, Twin, Heather C, Knegtel, Ronald M. A, Boyall, Dean, Brenchley, Guy, Davis, Christopher J, Keily, Shazia, Mak, Chau, Miller, Andrew, Pierard, Françoise, Settimo, Luca, Bolton, Clare M, Chiu, Peter, Curnock, Adam, Doyle, Elisabeth, Tanner, Adam J, Jimenez, Juan-Miguel
Published in ACS medicinal chemistry letters (08.08.2019)
Published in ACS medicinal chemistry letters (08.08.2019)
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Discovery and Structure−Activity Relationship of 3-Aminopyrid-2-ones as Potent and Selective Interleukin-2 Inducible T-Cell Kinase (Itk) Inhibitors
Charrier, Jean-Damien, Miller, Andrew, Kay, David P, Brenchley, Guy, Twin, Heather C, Collier, Philip N, Ramaya, Sharn, Keily, Shazia B, Durrant, Steven J, Knegtel, Ronald M. A, Tanner, Adam J, Brown, Kieron, Curnock, Adam P, Jimenez, Juan-Miguel
Published in Journal of medicinal chemistry (14.04.2011)
Published in Journal of medicinal chemistry (14.04.2011)
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Substituted 2,5-diazabicyclo[4.1.0]heptanes and their application as general piperazine surrogates: synthesis and biological activity of a Ciprofloxacin analogue
Taylor, Rivka R.R., Twin, Heather C., Wen, Wendy W., Mallot, Rebecca J., Lough, Alan J., Gray-Owen, Scott D., Batey, Robert A.
Published in Tetrahedron (01.05.2010)
Published in Tetrahedron (01.05.2010)
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Synthesis of a stable pyridyl boronate and its reaction with aryl and heteroaryl halides
Durrant, Steven J., Pinder, Joanne L., Charrier, Jean-Damien, Jimenez, Juan-Miguel, Brenchley, Guy, Collier, Philip N., Kay, David, Miller, Andrew, Pierard, Francoise, Ramaya, Sharn, Sadiq, Shazia, Twin, Heather C.
Published in Heterocycles (31.12.2006)
Published in Heterocycles (31.12.2006)
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