How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: Report of an ECVAM Workshop
Kirkland, David, Pfuhler, Stefan, Tweats, David, Aardema, Marilyn, Corvi, Raffaella, Darroudi, Firouz, Elhajouji, Azeddine, Glatt, Hansruedi, Hastwell, Paul, Hayashi, Makoto, Kasper, Peter, Kirchner, Stephan, Lynch, Anthony, Marzin, Daniel, Maurici, Daniela, Meunier, Jean-Roc, Müller, Lutz, Nohynek, Gerhard, Parry, James, Parry, Elizabeth, Thybaud, Veronique, Tice, Ray, van Benthem, Jan, Vanparys, Philippe, White, Paul
Published in Mutation research (30.03.2007)
Published in Mutation research (30.03.2007)
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Journal Article
Report of the IWGT working group on strategies and interpretation of regulatory in vivo tests I. Increases in micronucleated bone marrow cells in rodents that do not indicate genotoxic hazards
TWEATS, D. J, BLAKEY, D, TICE, R, HEFLICH, R. H, JACOBS, A, JACOBSEN, S. D, MORITA, T, NOHMI, T, O'DONOVAN, M. R, SASAKI, Y. F, SOFUNI, T
Published in Mutation research (03.02.2007)
Published in Mutation research (03.02.2007)
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Conference Proceeding
Journal Article
Testing strategies in mutagenicity and genetic toxicology: An appraisal of the guidelines of the European Scientific Committee for Cosmetics and Non-Food Products for the evaluation of hair dyes
Kirkland, D.J., Henderson, L., Marzin, D., Müller, L., Parry, J.M., Speit, G., Tweats, D.J., Williams, G.M.
Published in Mutation research (30.12.2005)
Published in Mutation research (30.12.2005)
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Journal Article
Report of the IWGT working group on strategy/interpretation for regulatory in vivo tests II. Identification of in vivo-only positive compounds in the bone marrow micronucleus test
TWEATS, D. J, BLAKEY, D, TICE, R, HEFLICH, R. H, JACOBS, A, JACOBSEN, S. D, MORITA, T, NOHMI, T, O'DONOVAN, M. R, SASAKI, Y. F, SOFUNI, T
Published in Mutation research (03.02.2007)
Published in Mutation research (03.02.2007)
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Conference Proceeding
Journal Article
The GreenScreen® genotoxicity assay: a screening validation programme
Cahill, P.A., Knight, A.W., Billinton, N., Barker, M.G., Walsh, L., Keenan, P.O., Williams, C.V., Tweats, D.J., Walmsley, R.M.
Published in Mutagenesis (01.03.2004)
Published in Mutagenesis (01.03.2004)
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Journal Article
An assessment of the utility of the yeast GreenScreen assay in pharmaceutical screening
Van Gompel, J., Woestenborghs, F., Beerens, D., Mackie, C., Cahill, P.A., Knight, A.W., Billinton, N., Tweats, D.J., Walmsley, R.M.
Published in Mutagenesis (01.11.2005)
Published in Mutagenesis (01.11.2005)
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Journal Article
An analysis of results from 305 compounds tested with the yeast RAD54-GFP genotoxicity assay (GreenScreen GC)—including relative predictivity of regulatory tests and rodent carcinogenesis and performance with autofluorescent and coloured compounds
Knight, Andrew W., Billinton, N., Cahill, P. A., Scott, A., Harvey, J. S., Roberts, K. J., Tweats, D. J., Keenan, P. O., Walmsley, R. M.
Published in Mutagenesis (01.11.2007)
Published in Mutagenesis (01.11.2007)
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Journal Article
Strategy for genotoxicity testing and stratification of genotoxicity test results—report on initial activities of the IWGT Expert Group
Müller, Lutz, Blakey, David, Dearfield, Kerry L., Galloway, Sheila, Guzzie, Peggy, Hayashi, Makoto, Kasper, Peter, Kirkland, David, MacGregor, James T., Parry, James M., Schechtman, Leonard, Smith, Andrew, Tanaka, Noriho, Tweats, David, Yamasaki, Hiroshi
Published in Mutation research (07.10.2003)
Published in Mutation research (07.10.2003)
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Journal Article
Conference Proceeding
Genotoxicity studies of gastric acid inhibiting drugs
Burlinson, B, Morriss, S H, Gatehouse, D G, Tweats, D J
Published in The Lancet (British edition) (17.02.1990)
Published in The Lancet (British edition) (17.02.1990)
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Journal Article
The preclinical toxicological evaluation of sumatriptan
Owen, K., Hartley, K., Tucker, ML, Parkinson, MM, Tweats, DJ, Jackson, MR
Published in Human & experimental toxicology (01.12.1995)
Published in Human & experimental toxicology (01.12.1995)
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Journal Article
Uptake of tritiated thymidine by cells of the rat gastric mucosa after exposure to loxtidine or omeprazole
Burlinson, B, Morriss, S, Gatehouse, D G, Tweats, D J, Jackson, M R
Published in Mutagenesis (01.01.1991)
Published in Mutagenesis (01.01.1991)
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Journal Article
The Viracept-EMS case: Impact and outlook
Walker, Vernon E., Casciano, Daniel A., Tweats, David J.
Published in Toxicology letters (12.11.2009)
Published in Toxicology letters (12.11.2009)
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