R306465 is a novel potent inhibitor of class I histone deacetylases with broad-spectrum antitumoral activity against solid and haematological malignancies
ARTS, J, ANGIBAUD, P, JOHNSON, D. L, ANDRIES, L, JUNG, M, JANICOT, M, VAN EMELEN, K, MARIËN, A, FLOREN, W, JANSSENS, B, KING, P, VAN DUN, J, JANSSEN, L, GEERTS, T, TUMAN, R. W
Published in British journal of cancer (19.11.2007)
Published in British journal of cancer (19.11.2007)
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N-GLUCURONIDATION OF THE PLATELET-DERIVED GROWTH FACTOR RECEPTOR TYROSINE KINASE INHIBITOR 6,7-(DIMETHOXY-2,4-DIHYDROINDENO[1,2-C]PYRAZOL-3-YL)-(3-FLUORO-PHENYL)-AMINE BY HUMAN UDP-GLUCURONOSYLTRANSFERASES
YAN, Z, CALDWELL, G. W, JOHNSON, D. L, GAUTHIER, D, LEO, G. C, MEI, J, HO, C. Y, JONES, W. J, MASUCCI, J. A, TUMAN, R. W, GALEMMO, R. A
Published in Drug metabolism and disposition (01.05.2006)
Published in Drug metabolism and disposition (01.05.2006)
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Automatic vessel segmentation and quantification of the rat aortic ring assay of angiogenesis
NISSANOV, J, TUMAN, R. W, GRUVER, L. M, FORTUNATO, J. M
Published in Laboratory investigation (01.11.1995)
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Published in Laboratory investigation (01.11.1995)
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Carbohydrate biguanides as potential hypoglycemic agents
Reitz, Allen B, Tuman, Robert W, Marchione, Carol S, Jordan, Alfonzo D, Bowden, Charles R, Maryanoff, Bruce E
Published in Journal of medicinal chemistry (01.09.1989)
Published in Journal of medicinal chemistry (01.09.1989)
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New non-steroidal aromatase inhibitors: Focus on R76713
De Coster, R., Wouters, W., Bowden, C.R., Vanden Bossche, H., Bruynseels, J., Tuman, R.W., Van Ginckel, R., Snoeck, E., Van Peer, A., Janssen, P.A.J.
Published in Journal of steroid biochemistry and molecular biology (20.11.1990)
Published in Journal of steroid biochemistry and molecular biology (20.11.1990)
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Conference Proceeding
Aromatase inhibition by R 76713: Experimental and clinical pharmacology
Wouters, W., De Coster, R., Tuman, R.W., Bowden, C.R., Bruynseets, J., Vanderpas, H., van Rooy, P., Amery, W.K., Janssen, P.A.J.
Published in Journal of steroid biochemistry (1989)
Published in Journal of steroid biochemistry (1989)
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Conference Proceeding
A NOVEL SERIES OF N-(1-AMINOALKYLIDENE)CARBOXIMIDAMIDES AS POTENTIAL HYPOGLYCEMIC AGENTS
BRESLIN, HJ, KUKLA, MJ, TUMAN, RW, REBARCHAK, MC, BOWDEN, CR
Published in Journal of medicinal chemistry (28.05.1993)
Published in Journal of medicinal chemistry (28.05.1993)
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Hypoglycaemic and hypoketonaemic effects of single and repeated oral doses of methyl palmoxirate (methyl 2‐tetradecylglycidate) in streptozotocin/alloxan‐induced diabetic dogs
Tuman, Robert W., Tutwiler, Gene F., Joseph, John M., Wallace, Nathaniel H.
Published in British journal of pharmacology (01.05.1988)
Published in British journal of pharmacology (01.05.1988)
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(6,7-Dimethoxy-2,4-dihydroindeno[1,2-c]pyrazol-3-yl)phenylamines: Platelet-Derived Growth Factor Receptor Tyrosine Kinase Inhibitors with Broad Antiproliferative Activity against Tumor Cells
Ho, Chih Y, Ludovici, Donald W, Maharoof, Umar S. M, Mei, Jay, Sechler, Jan L, Tuman, Robert W, Strobel, Eric D, Andraka, Laura, Yen, Hwa-Kwo, Leo, Gregory, Li, Jian, Almond, Harold, Lu, Hong, DeVine, Ann, Tominovich, Rose M, Baker, Judith, Emanuel, Stuart, Gruninger, Robert H, Middleton, Steven A, Johnson, Dana L, Galemmo, Robert A
Published in Journal of medicinal chemistry (29.12.2005)
Published in Journal of medicinal chemistry (29.12.2005)
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Validation of in vivo pharmacodynamic activity of a novel PDGF receptor tyrosine kinase inhibitor using immunohistochemistry and quantitative image analysis
D'Andrea, Michael R, Mei, Jay M, Tuman, Robert W, Galemmo, Robert A, Johnson, Dana L
Published in Molecular cancer therapeutics (01.08.2005)
Published in Molecular cancer therapeutics (01.08.2005)
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