SOX4 can redirect TGF-β-mediated SMAD3-transcriptional output in a context-dependent manner to promote tumorigenesis
Vervoort, Stephin J, Lourenço, Ana Rita, Tufegdzic Vidakovic, Ana, Mocholi, Enric, Sandoval, José L, Rueda, Oscar M, Frederiks, Cynthia, Pals, Cornelieke, Peeters, Janneke G C, Caldas, Carlos, Bruna, Alejandra, Coffer, Paul J
Published in Nucleic acids research (12.10.2018)
Published in Nucleic acids research (12.10.2018)
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Context-Specific Effects of TGF-β/SMAD3 in Cancer Are Modulated by the Epigenome
Tufegdzic Vidakovic, Ana, Rueda, Oscar M., Vervoort, Stephin J., Sati Batra, Ankita, Goldgraben, Mae Akilina, Uribe-Lewis, Santiago, Greenwood, Wendy, Coffer, Paul J., Bruna, Alejandra, Caldas, Carlos
Published in Cell reports (Cambridge) (22.12.2015)
Published in Cell reports (Cambridge) (22.12.2015)
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DNA methylation landscapes of 1538 breast cancers reveal a replication-linked clock, epigenomic instability and cis-regulation
Batra, Rajbir Nath, Lifshitz, Aviezer, Vidakovic, Ana Tufegdzic, Chin, Suet-Feung, Sati-Batra, Ankita, Sammut, Stephen-John, Provenzano, Elena, Ali, H. Raza, Dariush, Ali, Bruna, Alejandra, Murphy, Leigh, Purushotham, Arnie, Ellis, Ian, Green, Andrew, Garrett-Bakelman, Francine E., Mason, Chris, Melnick, Ari, Aparicio, Samuel A. J. R., Rueda, Oscar M., Tanay, Amos, Caldas, Carlos
Published in Nature communications (13.09.2021)
Published in Nature communications (13.09.2021)
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Analysis of RNA polymerase II ubiquitylation and proteasomal degradation
Tufegdzic Vidakovic, Ana, Harreman, Michelle, Dirac-Svejstrup, A. Barbara, Boeing, Stefan, Roy, Anindya, Encheva, Vesela, Neumann, Michelle, Wilson, Marcus, Snijders, Ambrosius P., Svejstrup, Jesper Q.
Published in Methods (San Diego, Calif.) (15.04.2019)
Published in Methods (San Diego, Calif.) (15.04.2019)
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Global transcriptional analysis identifies a novel role for SOX4 in tumor-induced angiogenesis
Vervoort, Stephin J, de Jong, Olivier G, Roukens, M Guy, Frederiks, Cynthia L, Vermeulen, Jeroen F, Lourenço, Ana Rita, Bella, Laura, Vidakovic, Ana Tufegdzic, Sandoval, José L, Moelans, Cathy, van Amersfoort, Miranda, Dallman, Margaret J, Bruna, Alejandra, Caldas, Carlos, Nieuwenhuis, Edward, van der Wall, Elsken, Derksen, Patrick, van Diest, Paul, Verhaar, Marianne C, Lam, Eric W-F, Mokry, Michal, Coffer, Paul J
Published in eLife (03.12.2018)
Published in eLife (03.12.2018)
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Regulation of the RNAPII Pool Is Integral to the DNA Damage Response
Tufegdžić Vidaković, Ana, Mitter, Richard, Kelly, Gavin P., Neumann, Michelle, Harreman, Michelle, Rodríguez-Martínez, Marta, Herlihy, Anna, Weems, Juston C., Boeing, Stefan, Encheva, Vesela, Gaul, Liam, Milligan, Laura, Tollervey, David, Conaway, Ronald C., Conaway, Joan W., Snijders, Ambrosius P., Stewart, Aengus, Svejstrup, Jesper Q.
Published in Cell (19.03.2020)
Published in Cell (19.03.2020)
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A Biobank of Breast Cancer Explants with Preserved Intra-tumor Heterogeneity to Screen Anticancer Compounds
Bruna, Alejandra, Rueda, Oscar M., Greenwood, Wendy, Batra, Ankita Sati, Callari, Maurizio, Batra, Rajbir Nath, Pogrebniak, Katherine, Sandoval, Jose, Cassidy, John W., Tufegdzic-Vidakovic, Ana, Sammut, Stephen-John, Jones, Linda, Provenzano, Elena, Baird, Richard, Eirew, Peter, Hadfield, James, Eldridge, Matthew, McLaren-Douglas, Anne, Barthorpe, Andrew, Lightfoot, Howard, O’Connor, Mark J., Gray, Joe, Cortes, Javier, Baselga, Jose, Marangoni, Elisabetta, Welm, Alana L., Aparicio, Samuel, Serra, Violeta, Garnett, Mathew J., Caldas, Carlos
Published in Cell (22.09.2016)
Published in Cell (22.09.2016)
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CDK13 cooperates with CDK12 to control global RNA polymerase II processivity
Fan, Zheng, Devlin, Jennifer R, Hogg, Simon J, Doyle, Maria A, Harrison, Paul F, Todorovski, Izabela, Cluse, Leonie A, Knight, Deborah A, Sandow, Jarrod J, Gregory, Gareth, Fox, Andrew, Beilharz, Traude H, Kwiatkowski, Nicholas, Scott, Nichollas E, Vidakovic, Ana Tufegdzic, Kelly, Gavin P, Svejstrup, Jesper Q, Geyer, Matthias, Gray, Nathanael S, Vervoort, Stephin J, Johnstone, Ricky W
Published in Science advances (01.05.2020)
Published in Science advances (01.05.2020)
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CDK13 cooperates with CDK12 to control global RNA polymerase II processivity
Fan, Zheng, Devlin, Jennifer R., Hogg, Simon J., Doyle, Maria A., Harrison, Paul F., Todorovski, Izabela, Cluse, Leonie A., Knight, Deborah A., Sandow, Jarrod J., Gregory, Gareth, Fox, Andrew, Beilharz, Traude H., Kwiatkowski, Nicholas, Scott, Nichollas E., Vidakovic, Ana Tufegdzic, Kelly, Gavin P., Svejstrup, Jesper Q., Geyer, Matthias, Gray, Nathanael S., Vervoort, Stephin J., Johnstone, Ricky W.
Published in Science advances (29.04.2020)
Published in Science advances (29.04.2020)
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TGFβ induces the formation of tumour-initiating cells in claudinlow breast cancer
Bruna, Alejandra, Greenwood, Wendy, Le Quesne, John, Teschendorff, Andrew, Miranda-Saavedra, Diego, Rueda, Oscar M., Sandoval, Jose L., Vidakovic, Ana Tufegdzic, Saadi, Amel, Pharoah, Paul, Stingl, John, Caldas, Carlos
Published in Nature communications (11.09.2012)
Published in Nature communications (11.09.2012)
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TGF[beta] induces the formation of tumour-initiating cells in claudinlow breast cancer
Bruna, Alejandra, Greenwood, Wendy, Le Quesne, John, Teschendorff, Andrew, Miranda-saavedra, Diego, Rueda, Oscar M, Sandoval, Jose L, Vidakovic, Ana Tufegdzic, Saadi, Amel, Pharoah, Paul, Stingl, John, Caldas, Carlos
Published in Nature communications (01.09.2012)
Published in Nature communications (01.09.2012)
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