A Non-canonical Voltage-Sensing Mechanism Controls Gating in K2P K+ Channels
Schewe, Marcus, Nematian-Ardestani, Ehsan, Sun, Han, Musinszki, Marianne, Cordeiro, Sönke, Bucci, Giovanna, de Groot, Bert L., Tucker, Stephen J., Rapedius, Markus, Baukrowitz, Thomas
Published in Cell (25.02.2016)
Published in Cell (25.02.2016)
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Journal Article
Induced Polarization in Molecular Dynamics Simulations of the 5-HT3 Receptor Channel
Klesse, Gianni, Rao, Shanlin, Tucker, Stephen J, Sansom, Mark S.P
Published in Journal of the American Chemical Society (20.05.2020)
Published in Journal of the American Chemical Society (20.05.2020)
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Journal Article
Structure and assembly of calcium homeostasis modulator proteins
Syrjanen, Johanna L., Michalski, Kevin, Chou, Tsung-Han, Grant, Timothy, Rao, Shanlin, Simorowski, Noriko, Tucker, Stephen J., Grigorieff, Nikolaus, Furukawa, Hiro
Published in Nature structural & molecular biology (01.02.2020)
Published in Nature structural & molecular biology (01.02.2020)
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Journal Article
A heuristic derived from analysis of the ion channel structural proteome permits the rapid identification of hydrophobic gates
Rao, Shanlin, Klesse, Gianni, Stansfeld, Phillip J., Tucker, Stephen J., Sansom, Mark S. P.
Published in Proceedings of the National Academy of Sciences - PNAS (09.07.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (09.07.2019)
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Journal Article
A hydrophobic barrier deep within the inner pore of the TWIK-1 K2P potassium channel
Aryal, Prafulla, Abd-Wahab, Firdaus, Bucci, Giovanna, Sansom, Mark S. P., Tucker, Stephen J.
Published in Nature communications (08.07.2014)
Published in Nature communications (08.07.2014)
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Journal Article
Structural basis for proton coupled cystine transport by cystinosin
Löbel, Mark, Salphati, Sacha P., El Omari, Kamel, Wagner, Armin, Tucker, Stephen J., Parker, Joanne L., Newstead, Simon
Published in Nature communications (17.08.2022)
Published in Nature communications (17.08.2022)
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Journal Article
Influence of effective polarization on ion and water interactions within a biomimetic nanopore
Phan, Linda X., Lynch, Charlotte I., Crain, Jason, Sansom, Mark S.P., Tucker, Stephen J.
Published in Biophysical journal (07.06.2022)
Published in Biophysical journal (07.06.2022)
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Journal Article
The pore structure and gating mechanism of K2P channels
Piechotta, Paula L, Rapedius, Markus, Stansfeld, Phillip J, Bollepalli, Murali K, Erhlich, Gunter, Andres-Enguix, Isabelle, Fritzenschaft, Hariolf, Decher, Niels, Sansom, Mark S P, Tucker, Stephen J, Baukrowitz, Thomas
Published in The EMBO journal (31.08.2011)
Published in The EMBO journal (31.08.2011)
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Journal Article
Transcending Markov: non-Markovian rate processes of thermosensitive TRP ion channels
Ben-Abu, Yuval, Tucker, Stephen J, Contera, Sonia
Published in Royal Society open science (23.08.2023)
Published in Royal Society open science (23.08.2023)
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Journal Article
Solution-Based Single-Molecule FRET Studies of K+ Channel Gating in a Lipid Bilayer
Sadler, Emma E., Kapanidis, Achillefs N., Tucker, Stephen J.
Published in Biophysical journal (21.06.2016)
Published in Biophysical journal (21.06.2016)
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Journal Article
Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation
Rödström, Karin E. J., Cloake, Alexander, Sörmann, Janina, Baronina, Agnese, Smith, Kathryn H. M., Pike, Ashley C. W., Ang, Jackie, Proks, Peter, Schewe, Marcus, Holland-Kaye, Ingelise, Bushell, Simon R., Elliott, Jenna, Pardon, Els, Baukrowitz, Thomas, Owens, Raymond J., Newstead, Simon, Steyaert, Jan, Carpenter, Elisabeth P., Tucker, Stephen J.
Published in Nature communications (16.05.2024)
Published in Nature communications (16.05.2024)
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Journal Article
KCNK18 Biallelic Variants Associated with Intellectual Disability and Neurodevelopmental Disorders Alter TRESK Channel Activity
Pavinato, Lisa, Nematian-Ardestani, Ehsan, Zonta, Andrea, De Rubeis, Silvia, Buxbaum, Joseph, Mancini, Cecilia, Bruselles, Alessandro, Tartaglia, Marco, Pessia, Mauro, Tucker, Stephen J., D’Adamo, Maria Cristina, Brusco, Alfredo
Published in International journal of molecular sciences (04.06.2021)
Published in International journal of molecular sciences (04.06.2021)
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Journal Article
Renal phenotype in mice lacking the Kir5.1 (Kcnj16) K+channel subunit contrasts with that observed in SeSAME/EAST syndrome
Paulais, Marc, Bloch-Faure, May, Picard, Nicolas, Jacques, Thibaut, Ramakrishnan, Suresh Krishna, Keck, Mathilde, Sohet, Fabien, Eladari, Dominique, Houillier, Pascal, Lourdel, Stéphane, Teulon, Jacques, Tucker, Stephen J.
Published in Proceedings of the National Academy of Sciences - PNAS (21.06.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (21.06.2011)
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Kcnj16 (Kir5.1) Gene Ablation Causes Subfertility and Increases the Prevalence of Morphologically Abnormal Spermatozoa
Poli, Giulia, Hasan, Sonia, Belia, Silvia, Cenciarini, Marta, Tucker, Stephen J, Imbrici, Paola, Shehab, Safa, Pessia, Mauro, Brancorsini, Stefano, D'Adamo, Maria Cristina
Published in International journal of molecular sciences (01.06.2021)
Published in International journal of molecular sciences (01.06.2021)
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Journal Article
Structure of a KirBac potassium channel with an open bundle crossing indicates a mechanism of channel gating
Bavro, Vassiliy N, De Zorzi, Rita, Schmidt, Matthias R, Muniz, João R C, Zubcevic, Lejla, Sansom, Mark S P, Vénien-Bryan, Catherine, Tucker, Stephen J
Published in Nature structural & molecular biology (01.02.2012)
Published in Nature structural & molecular biology (01.02.2012)
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Journal Article
Crystal Structures of the Extracellular Domain from PepT1 and PepT2 Provide Novel Insights into Mammalian Peptide Transport
Beale, John H., Parker, Joanne L., Samsudin, Firdaus, Barrett, Anne L., Senan, Anish, Bird, Louise E., Scott, David, Owens, Raymond J., Sansom, Mark S.P., Tucker, Stephen J., Meredith, David, Fowler, Philip W., Newstead, Simon
Published in Structure (London) (06.10.2015)
Published in Structure (London) (06.10.2015)
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