Transcriptional and Cellular Diversity of the Human Heart
Tucker, Nathan R., Chaffin, Mark, Fleming, Stephen J., Hall, Amelia W., Parsons, Victoria A., Bedi, Kenneth C., Akkad, Amer-Denis, Herndon, Caroline N., Arduini, Alessandro, Papangeli, Irinna, Roselli, Carolina, Aguet, François, Choi, Seung Hoan, Ardlie, Kristin G., Babadi, Mehrtash, Margulies, Kenneth B., Stegmann, Christian M., Ellinor, Patrick T.
Published in Circulation (New York, N.Y.) (04.08.2020)
Published in Circulation (New York, N.Y.) (04.08.2020)
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Journal Article
Myocyte-Specific Upregulation of ACE2 in Cardiovascular Disease: Implications for SARS-CoV-2–Mediated Myocarditis
Tucker, Nathan R., Chaffin, Mark, Bedi, Kenneth C., Papangeli, Irinna, Akkad, Amer-Denis, Arduini, Alessandro, Hayat, Sikander, Eraslan, Gökcen, Muus, Christoph, Bhattacharyya, Roby P., Stegmann, Christian M., Margulies, Kenneth B., Ellinor, Patrick T.
Published in Circulation (New York, N.Y.) (18.08.2020)
Published in Circulation (New York, N.Y.) (18.08.2020)
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Journal Article
COVID-19 and Cardiovascular Disease: From Bench to Bedside
Chung, Mina K., Zidar, David A., Bristow, Michael R., Cameron, Scott J., Chan, Timothy, Harding, Clifford V., Kwon, Deborah H., Singh, Tamanna, Tilton, John C., Tsai, Emily J., Tucker, Nathan R., Barnard, John, Loscalzo, Joseph
Published in Circulation research (16.04.2021)
Published in Circulation research (16.04.2021)
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Journal Article
Single-nucleus profiling of human dilated and hypertrophic cardiomyopathy
Chaffin, Mark, Papangeli, Irinna, Simonson, Bridget, Akkad, Amer-Denis, Hill, Matthew C., Arduini, Alessandro, Fleming, Stephen J., Melanson, Michelle, Hayat, Sikander, Kost-Alimova, Maria, Atwa, Ondine, Ye, Jiangchuan, Bedi, Kenneth C., Nahrendorf, Matthias, Kaushik, Virendar K., Stegmann, Christian M., Margulies, Kenneth B., Tucker, Nathan R., Ellinor, Patrick T.
Published in Nature (London) (04.08.2022)
Published in Nature (London) (04.08.2022)
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Journal Article
PHACTR1 Is a Genetic Susceptibility Locus for Fibromuscular Dysplasia Supporting Its Complex Genetic Pattern of Inheritance
Kiando, Soto Romuald, Tucker, Nathan R, Castro-Vega, Luis-Jaime, Katz, Alexander, D'Escamard, Valentina, Tréard, Cyrielle, Fraher, Daniel, Albuisson, Juliette, Kadian-Dodov, Daniella, Ye, Zi, Austin, Erin, Yang, Min-Lee, Hunker, Kristina, Barlassina, Cristina, Cusi, Daniele, Galan, Pilar, Empana, Jean-Philippe, Jouven, Xavier, Gimenez-Roqueplo, Anne-Paule, Bruneval, Patrick, Hyun Kim, Esther Soo, Olin, Jeffrey W, Gornik, Heather L, Azizi, Michel, Plouin, Pierre-François, Ellinor, Patrick T, Kullo, Iftikhar J, Milan, David J, Ganesh, Santhi K, Boutouyrie, Pierre, Kovacic, Jason C, Jeunemaitre, Xavier, Bouatia-Naji, Nabila
Published in PLoS genetics (28.10.2016)
Published in PLoS genetics (28.10.2016)
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Journal Article
Transcriptome variation in human tissues revealed by long-read sequencing
Glinos, Dafni A., Garborcauskas, Garrett, Hoffman, Paul, Ehsan, Nava, Jiang, Lihua, Gokden, Alper, Dai, Xiaoguang, Aguet, François, Brown, Kathleen L., Garimella, Kiran, Bowers, Tera, Costello, Maura, Ardlie, Kristin, Jian, Ruiqi, Tucker, Nathan R., Ellinor, Patrick T., Harrington, Eoghan D., Tang, Hua, Snyder, Michael, Juul, Sissel, Mohammadi, Pejman, MacArthur, Daniel G., Lappalainen, Tuuli, Cummings, Beryl B.
Published in Nature (London) (11.08.2022)
Published in Nature (London) (11.08.2022)
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Journal Article
Common variation in atrial fibrillation: navigating the path from genetic association to mechanism
Tucker, Nathan R, Clauss, Sebastian, Ellinor, Patrick T
Published in Cardiovascular research (01.04.2016)
Published in Cardiovascular research (01.04.2016)
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Journal Article
Deep learning enables genetic analysis of the human thoracic aorta
Pirruccello, James P., Chaffin, Mark D., Chou, Elizabeth L., Fleming, Stephen J., Lin, Honghuang, Nekoui, Mahan, Khurshid, Shaan, Friedman, Samuel F., Bick, Alexander G., Arduini, Alessandro, Weng, Lu-Chen, Choi, Seung Hoan, Akkad, Amer-Denis, Batra, Puneet, Tucker, Nathan R., Hall, Amelia W., Roselli, Carolina, Benjamin, Emelia J., Vellarikkal, Shamsudheen K., Gupta, Rajat M., Stegmann, Christian M., Juric, Dejan, Stone, James R., Vasan, Ramachandran S., Ho, Jennifer E., Hoffmann, Udo, Lubitz, Steven A., Philippakis, Anthony A., Lindsay, Mark E., Ellinor, Patrick T.
Published in Nature genetics (01.01.2022)
Published in Nature genetics (01.01.2022)
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Journal Article
Association Between Titin Loss-of-Function Variants and Early-Onset Atrial Fibrillation
Choi, Seung Hoan, Weng, Lu-Chen, Roselli, Carolina, Lin, Honghuang, Haggerty, Christopher M, Shoemaker, M. Benjamin, Barnard, John, Arking, Dan E, Chasman, Daniel I, Albert, Christine M, Chaffin, Mark, Tucker, Nathan R, Smith, Jonathan D, Gupta, Namrata, Gabriel, Stacey, Margolin, Lauren, Shea, Marisa A, Shaffer, Christian M, Yoneda, Zachary T, Boerwinkle, Eric, Smith, Nicholas L, Silverman, Edwin K, Redline, Susan, Vasan, Ramachandran S, Burchard, Esteban G, Gogarten, Stephanie M, Laurie, Cecelia, Blackwell, Thomas W, Abecasis, Gonçalo, Carey, David J, Fornwalt, Brandon K, Smelser, Diane T, Baras, Aris, Dewey, Frederick E, Jaquish, Cashell E, Papanicolaou, George J, Sotoodehnia, Nona, Van Wagoner, David R, Psaty, Bruce M, Kathiresan, Sekar, Darbar, Dawood, Alonso, Alvaro, Heckbert, Susan R, Chung, Mina K, Roden, Dan M, Benjamin, Emelia J, Murray, Michael F, Lunetta, Kathryn L, Lubitz, Steven A, Ellinor, Patrick T
Published in JAMA : the journal of the American Medical Association (11.12.2018)
Published in JAMA : the journal of the American Medical Association (11.12.2018)
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Journal Article
Epigenetic and Transcriptional Networks Underlying Atrial Fibrillation
van Ouwerkerk, Antoinette F., Hall, Amelia W., Kadow, Zachary A., Lazarevic, Sonja, Reyat, Jasmeet S., Tucker, Nathan R., Nadadur, Rangarajan D., Bosada, Fernanda M., Bianchi, Valerio, Ellinor, Patrick T., Fabritz, Larissa, Martin, James F., de Laat, Wouter, Kirchhof, Paulus, Moskowitz, Ivan P., Christoffels, Vincent M.
Published in Circulation research (19.06.2020)
Published in Circulation research (19.06.2020)
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Journal Article
Long-range Pitx2c enhancer–promoter interactions prevent predisposition to atrial fibrillation
Zhang, Min, Hill, Matthew C., Kadow, Zachary A., Suh, Ji Ho, Tucker, Nathan R., Hall, Amelia W., Tran, Tien T., Swinton, Paul S., Leach, John P., Margulies, Kenneth B., Ellinor, Patrick T., Li, Na, Martin, James F.
Published in Proceedings of the National Academy of Sciences - PNAS (05.11.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (05.11.2019)
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Journal Article
Large-scale single-nuclei profiling identifies role for ATRNL1 in atrial fibrillation
Hill, Matthew C., Simonson, Bridget, Roselli, Carolina, Xiao, Ling, Herndon, Caroline N., Chaffin, Mark, Mantineo, Helene, Atwa, Ondine, Bhasin, Harshit, Guedira, Yasmine, Bedi, Kenneth C., Margulies, Kenneth B., Klattenhoff, Carla A., Tucker, Nathan R., Ellinor, Patrick T.
Published in Nature communications (19.11.2024)
Published in Nature communications (19.11.2024)
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Journal Article
Increased atrial effectiveness of flecainide conferred by altered biophysical properties of sodium channels
O' Brien, Sian, Holmes, Andrew P., Johnson, Daniel M., Kabir, S. Nashitha, O' Shea, Christopher, O' Reilly, Molly, Avezzu, Adelisa, Reyat, Jasmeet S., Hall, Amelia W., Apicella, Clara, Ellinor, Patrick T., Niederer, Steven, Tucker, Nathan R., Fabritz, Larissa, Kirchhof, Paulus, Pavlovic, Davor
Published in Journal of molecular and cellular cardiology (01.05.2022)
Published in Journal of molecular and cellular cardiology (01.05.2022)
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Journal Article
Identification of Functional Variant Enhancers Associated With Atrial Fibrillation
van Ouwerkerk, Antoinette F., Bosada, Fernanda M., Liu, Jia, Zhang, Juan, van Duijvenboden, Karel, Chaffin, Mark, Tucker, Nathan R., Pijnappels, Daniel, Ellinor, Patrick T., Barnett, Phil, de Vries, Antoine A.F., Christoffels, Vincent M.
Published in Circulation research (03.07.2020)
Published in Circulation research (03.07.2020)
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Journal Article
How Does COVID-19 Affect the Heart?
Sewanan, Lorenzo R., Clerkin, Kevin J., Tucker, Nathan R., Tsai, Emily J.
Published in Current cardiology reports (01.03.2023)
Published in Current cardiology reports (01.03.2023)
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Journal Article
Loss of the Atrial Fibrillation-Related Gene, Zfhx3, Results in Atrial Dilation and Arrhythmias
Jameson, Heather S., Hanley, Alan, Hill, Matthew C., Xiao, Ling, Ye, Jiangchuan, Bapat, Aneesh, Ronzier, Elsa, Hall, Amelia Weber, Hucker, William J., Clauss, Sebastian, Barazza, Miranda, Silber, Elizabeth, Mina, Julie, Tucker, Nathan R., Mills, Robert W., Dong, Jin-Tang, Milan, David J., Ellinor, Patrick T.
Published in Circulation research (04.08.2023)
Published in Circulation research (04.08.2023)
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Journal Article
Discovery and validation of sub-threshold genome-wide association study loci using epigenomic signatures
Wang, Xinchen, Tucker, Nathan R, Rizki, Gizem, Mills, Robert, Krijger, Peter Hl, de Wit, Elzo, Subramanian, Vidya, Bartell, Eric, Nguyen, Xinh-Xinh, Ye, Jiangchuan, Leyton-Mange, Jordan, Dolmatova, Elena V, van der Harst, Pim, de Laat, Wouter, Ellinor, Patrick T, Newton-Cheh, Christopher, Milan, David J, Kellis, Manolis, Boyer, Laurie A
Published in eLife (10.05.2016)
Published in eLife (10.05.2016)
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Journal Article