FAST: a randomised phase II study of zolbetuximab (IMAB362) plus EOX versus EOX alone for first-line treatment of advanced CLDN18.2-positive gastric and gastro-oesophageal adenocarcinoma
Sahin, U., Türeci, Ö., Manikhas, G., Lordick, F., Rusyn, A., Vynnychenko, I., Dudov, A., Bazin, I., Bondarenko, I., Melichar, B., Dhaene, K., Wiechen, K., Huber, C., Maurus, D., Arozullah, A., Park, J.W., Schuler, M., Al-Batran, S.-E.
Published in Annals of oncology (01.05.2021)
Published in Annals of oncology (01.05.2021)
Get full text
Journal Article
A role for T-bet-mediated tumour immune surveillance in anti-IL-17A treatment of lung cancer
Reppert, S., Boross, I., Koslowski, M., Türeci, Ö., Koch, S., Lehr, H.A., Finotto, S.
Published in Nature communications (20.12.2011)
Published in Nature communications (20.12.2011)
Get full text
Journal Article
A multicentre, phase IIa study of zolbetuximab as a single agent in patients with recurrent or refractory advanced adenocarcinoma of the stomach or lower oesophagus: the MONO study
Türeci, O., Sahin, U., Schulze-Bergkamen, H., Zvirbule, Z., Lordick, F., Koeberle, D., Thuss-Patience, P., Ettrich, T., Arnold, D., Bassermann, F., Al-Batran, S.E., Wiechen, K., Dhaene, K., Maurus, D., Gold, M., Huber, C., Krivoshik, A., Arozullah, A., Park, J.W., Schuler, M.
Published in Annals of oncology (01.09.2019)
Published in Annals of oncology (01.09.2019)
Get full text
Journal Article
Translation of genomics-guided RNA-based personalised cancer vaccines: towards the bedside
Boisguérin, V, Castle, J C, Loewer, M, Diekmann, J, Mueller, F, Britten, C M, Kreiter, S, Türeci, Ö, Sahin, U
Published in British journal of cancer (14.10.2014)
Published in British journal of cancer (14.10.2014)
Get full text
Journal Article
1196TiP LuCa-MERIT-1: First-in-human, open label, phase I dose confirmation trial evaluating the safety, tolerability, and preliminary efficacy of BNT116 alone and in combinations in patients with advanced non-small cell lung cancer
Forde, P.M., Atmaca, A., Brück, P., Munshi, N., Kaczorowska, M.A., Schell, T., Türeci, Ö., Sahin, U.
Published in Annals of oncology (01.09.2022)
Published in Annals of oncology (01.09.2022)
Get full text
Journal Article
999MO HARE-40: A phase I/II trial of therapeutic HPV vaccine (BNT113) in patients with HPV16 driven carcinoma
Ottensmeier, C.H.H., King, E., Crabb, S., Karydis, I., Graham, D.M., Martin, K., Eberhart, I., Ewings, S., Lee, P., McCann, K., Chudley, L., Berry, L., Dias, J., Das, R., Furlanetto, J., Johnson, E., Setzer, J., Sahin, U., Türeci, Ö., Griffiths, G.
Published in Annals of oncology (01.09.2024)
Published in Annals of oncology (01.09.2024)
Get full text
Journal Article
Preclinical characterization of IMAB362-vcMMAE, an anti-CLDN18.2 antibody–drug conjugate
Kreuzberg, M., Mitnacht-Kraus, R., Sahin, U., Türeci, Ö.
Published in Annals of oncology (01.09.2017)
Published in Annals of oncology (01.09.2017)
Get full text
Journal Article
1072P DuoBody-EpCAMx4-1BB mediates conditional T cell co-stimulation and promotes antitumor activity in preclinical models
Fellermeier-Kopf, S., Ioan-Facsinay, A., Imle, A., Diks, A.M., Nuermberger, K.B., Guelen, L., Köhne, M., Houtkamp, M., Toker, A., Burm, S.M., Gamse, J., Janaitis, C., Satijn, D., Muik, A., Ahmadi, T., Türeci, Ö., Kemper, K., Sahin, U., Breij, E.
Published in Annals of oncology (01.10.2023)
Published in Annals of oncology (01.10.2023)
Get full text
Journal Article
LBA35 BNT211-01: Interim results from a repeat dose escalation study of CLDN6 CAR-T cells manufactured with an automated process ± a CLDN6-encoding CAR-T cell-amplifying RNA Vaccine (CARVac)
Mackensen, A., Haanen, J.B.A.G., Alsdorf, W., Koenecke, C., Wagner-Drouet, E., Borchmann, P., Heudobler, D., Busse, A., Klobuch, S., Kutsch, N., Müller, F., Bokemeyer, C., Desuki, A., Lueke, F., Ho, T., Vemuri, K., Preussner, L., Rengstl, B., Türeci, Ö., Sahin, U.
Published in Annals of oncology (01.10.2023)
Published in Annals of oncology (01.10.2023)
Get full text
Journal Article
611O Updated results from BNT211-01 (NCT04503278), an ongoing, first-in-human, phase I study evaluating safety and efficacy of CLDN6 CAR T cells and a CLDN6-encoding mRNA vaccine in patients with relapsed/refractory CLDN6+ solid tumors
Haanen, J.B.A.G., Mackensen, A., Schultze-Florey, C., Alsdorf, W., Wagner-Drouet, E., Heudobler, D., Borchmann, P., Busse, A., Mielke, S., Bins, S., Ungerechts, G., Bokemeyer, C., Klobuch, S., Kutsch, N., Müller, F., Desuki, A., Zhong, W., Preussner, L., Türeci, Ö., Sahin, U.
Published in Annals of oncology (01.09.2024)
Published in Annals of oncology (01.09.2024)
Get full text
Journal Article
877P Exploratory efficacy and translational results from the safety run in of AHEAD-MERIT, a phase II trial of first line pembrolizumab plus the fixed-antigen cancer vaccine BNT113 in advanced HPV16+ HNSCC
Saba, N.F., Klinghammer, K., Castelluci, E., Colevas, A.D., Rutkowski, T., Thurner, D., Müller-Richter, U., Maio, M., Grewal, J.S., Ottensmeier, C.H.H., Dias, J., Yang, H., Das, R., Furlanetto, J., Herzfeldt, A-K., Kühnle, M-C., Ulges, A., Alles, J., Türeci, Ö., Sahin, U.
Published in Annals of oncology (01.09.2024)
Published in Annals of oncology (01.09.2024)
Get full text
Journal Article
29P Characterization of T cell responses induced by the individualized mRNA neoantigen vaccine autogene cevumeran in adjuvant stage II (high risk)/stage III colorectal cancer (CRC) patients (pts) from the biomarker cohort of the phase II BNT122-01 trial
Elez Fernandez, M.E., Maurel, J., Morris, V., Kopetz, S., Galligan, B., Ali, S., Derhovanessian, E., Unsal-Kacmaz, K., Manning, L., Henn, H., Weisenburger, T., Tonigold, M., Zurek, P., Fierek-Ulbig, M., Cortini, A., Pino Claveria, M., Preussner, L., Mueller, F., Türeci, Ö., Sahin, U.
Published in Annals of oncology (01.06.2024)
Published in Annals of oncology (01.06.2024)
Get full text
Journal Article
Molecular characterization of virus-induced autoantibody responses
Krebs, P, Ludewig, B, Metters, Türeci, Ö, Sahin, U
Published in Cancer cell international (01.07.2004)
Published in Cancer cell international (01.07.2004)
Get full text
Journal Article
LBA1 BNT211: A phase I/II trial to evaluate safety and efficacy of CLDN6 CAR-T cells and CARVac-mediated in vivo expansion in patients with CLDN6+ advanced solid tumors
Haanen, J., Mackensen, A., Koenecke, C., Alsdorf, W., Desuki, A., Wagner-Drouet, E., Heudobler, D., Borchmann, P., Wiegert, E., Schulz, C., Rengstl, B., Preußner, L., Türeci, Ö., Sahin, U.
Published in Annals of oncology (01.12.2021)
Published in Annals of oncology (01.12.2021)
Get full text
Journal Article
Phosphorothioate cap analogs increase stability and translational efficiency of RNA vaccines in immature dendritic cells and induce superior immune responses in vivo
Kuhn, A N, Diken, M, Kreiter, S, Selmi, A, Kowalska, J, Jemielity, J, Darzynkiewicz, E, Huber, C, Türeci, Ö, Sahin, U
Published in Gene therapy (01.08.2010)
Published in Gene therapy (01.08.2010)
Get full text
Journal Article
1558O COVID-19 vaccine in participants (ptcpts) with cancer: Subgroup analysis of efficacy/safety from a global phase III randomized trial of the BNT162b2 (tozinameran) mRNA vaccine
Thomas, S.J., Perez, J.L., Lockhart, S.P., Hariharan, S., Kitchin, N., Bailey, R., Liau, K., Lagkadinou, E., Türeci, Ö., Şahin, U., Xu, X., Dychter, S.S., Lu, C., Gentile, T., Gruber, W.
Published in Annals of oncology (01.09.2021)
Published in Annals of oncology (01.09.2021)
Get full text
Journal Article
Preclinical characterization of IMAB362 for the treatment of gastric carcinoma
Mitnacht-Kraus, R., Kreuzberg, M., Utsch, M., Sahin, U., Türeci, Ö.
Published in Annals of oncology (01.09.2017)
Published in Annals of oncology (01.09.2017)
Get full text
Journal Article
Preclinical evaluation of the anti-CLDN18.2 antibody, IMAB362, in pancreatic carcinoma
Heinz, C., Mitnacht-Kraus, R., Kreuzberg, M., Wöll, S., Sahin, U., Türeci, Ö.
Published in Annals of oncology (01.09.2017)
Published in Annals of oncology (01.09.2017)
Get full text
Journal Article
First-in-human study of IMAB362, an anti-claudin 18.2 monoclonal antibody, in patients with advanced gastroesophageal cancer
Sahin, U., Schuler, M., Bauer, S., Krilova, A., Utsch, M., Huber, C., Türeci, Ö.
Published in Annals of oncology (01.09.2017)
Published in Annals of oncology (01.09.2017)
Get full text
Journal Article