Targeting C/EBPα overcomes primary resistance and improves the efficacy of FLT3 inhibitors in acute myeloid leukaemia
Wang, Hanlin, Luo, Guanghao, Hu, Xiaobei, Xu, Gaoya, Wang, Tao, Liu, Minmin, Qiu, Xiaohui, Li, Jianan, Fu, Jingfeng, Feng, Bo, Tu, Yutong, Kan, Weijuan, Wang, Chang, Xu, Ran, Zhou, Yubo, Yang, Jianmin, Li, Jia
Published in Nature communications (05.04.2023)
Published in Nature communications (05.04.2023)
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Journal Article
Dual inhibition of CHK1/FLT3 enhances cytotoxicity and overcomes adaptive and acquired resistance in FLT3-ITD acute myeloid leukemia
Jiang, Kailong, Li, Xuemei, Wang, Chang, Hu, Xiaobei, Wang, Peipei, Tong, Lexian, Tu, Yutong, Chen, Beijing, Jin, Tingting, Wang, Tao, Wang, Hanlin, Han, Yubing, Gui, Renzhao, Yang, Jianmin, Liu, Tao, Li, Jia, Zhou, Yubo
Published in Leukemia (01.03.2023)
Published in Leukemia (01.03.2023)
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Journal Article
Proteasome activation: A novel strategy for targeting undruggable intrinsically disordered proteins
Yu, Qian, Wang, Zheng, Tu, Yutong, Cao, Yu, Zhu, Huajian, Shao, Jiaan, Zhuang, Rangxiao, Zhou, Yubo, Zhang, Jiankang
Published in Bioorganic chemistry (01.04.2024)
Published in Bioorganic chemistry (01.04.2024)
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Journal Article
Metabolism guided optimization of peptidomimetics as non-covalent proteasome inhibitors for cancer treatment
Cao, Yu, Tu, Yutong, Fu, Liping, Yu, Qian, Gao, Lixin, Zhang, Mengmeng, Zeng, Linghui, Zhang, Chong, Shao, Jiaan, Zhu, Huajian, Zhou, Yubo, Li, Jia, Zhang, Jiankang
Published in European journal of medicinal chemistry (05.04.2022)
Published in European journal of medicinal chemistry (05.04.2022)
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Journal Article
Design, Synthesis, and Biological Evaluation of 2,4-Diaminopyrimidine Derivatives as Potent CDK7 Inhibitors
Zhang, Hualin, Tu, Yutong, Tao, Zhaofan, Gao, Lixin, Huang, Shengjie, Gao, Mingshan, Mao, Jialuo, Zhou, Yang, Li, Yupeng, Li, Jia, Zhou, Yubo, Xu, Tianfeng
Published in ACS medicinal chemistry letters (08.08.2024)
Published in ACS medicinal chemistry letters (08.08.2024)
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Journal Article
DiPTAC: A degradation platform via directly targeting proteasome
Tu, Yutong, Yu, Qian, Li, Mengna, Gao, Lixin, Mao, Jialuo, Ma, Jingkun, Dong, Xiaowu, Che, Jinxin, Zhang, Chong, Zeng, Linghui, Zhu, Huajian, Shao, Jiaan, Hou, Jingli, Hu, Liming, Wan, Bingbing, Li, Jia, Zhou, Yubo, Zhang, Jiankang
Published in Acta pharmaceutica Sinica. B (01.09.2024)
Published in Acta pharmaceutica Sinica. B (01.09.2024)
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Journal Article
2, 4-diaminopyrimidine derivative as well as preparation method and application thereof
ZHOU YUBO, ZHANG HUALIN, LI JIA, GU YUEJIAO, XU TIANFENG, DIAO XINGXING, TAO ZHAOFAN, TU YUTONG, GAO LIXIN
Year of Publication 24.05.2024
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Year of Publication 24.05.2024
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