Discovery of orally bioavailable phosphonate prodrugs of potent ENPP1 inhibitors for cancer treatment
Gao, Shanyun, Hou, Yingjie, Xu, Yanxiao, Li, Jingjing, Zhang, Chaobo, Jiang, Shujuan, Yu, Songda, Liu, Lei, Tu, Wangyang, Yu, Bing, Zhang, Yixiang, Li, Leping
Published in European journal of medicinal chemistry (05.12.2024)
Published in European journal of medicinal chemistry (05.12.2024)
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Lead Identification of Novel Naphthyridine Derivatives as Potent SOS1 Inhibitors
Li, Dongsheng, Xie, Qing, Yang, Maozhi, Cai, Yalei, Sun, Kang, Jiang, Shujuan, Yu, Songda, Liu, Lei, Zhang, Yixiang, Yu, Bing, Tu, Wangyang, Li, Leping
Published in ACS medicinal chemistry letters (13.06.2024)
Published in ACS medicinal chemistry letters (13.06.2024)
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Discovery of Highly Potent and Selective IRAK1 Degraders to Probe Scaffolding Functions of IRAK1 in ABC DLBCL
Fu, Liqiang, Zhang, Jing, Shen, Bin, Kong, Linglong, Liu, Yingtao, Tu, Wangyang, Wang, Wenqian, Cai, Xin, Wang, Xiaotao, Cheng, Na, Xia, Mingxuan, Zhou, Tianyuan, Liu, Qian, Xu, Yanping, Yang, Jennifer, Gavine, Paul, Philippar, Ulrike, Attar, Ricardo, Edwards, James P, Venable, Jennifer D, Dai, Xuedong
Published in Journal of medicinal chemistry (12.08.2021)
Published in Journal of medicinal chemistry (12.08.2021)
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Discovery of Imidazoisoindole Derivatives as Highly Potent and Orally Active Indoleamine-2,3-dioxygenase Inhibitors
Tu, Wangyang, Yang, Fanglong, Xu, Guoji, Chi, Jiangtao, Liu, Zhiwei, Peng, Wei, Hu, Bing, Zhang, Lei, Wan, Hong, Yu, Nan, Jin, Fangfang, Hu, Qiyue, Zhang, Lianshan, He, Feng, Tao, Weikang
Published in ACS medicinal chemistry letters (13.06.2019)
Published in ACS medicinal chemistry letters (13.06.2019)
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Abstract LB032: HH102007 is a highly selective and potent PARP1 inhibitor and trapper
Hou, Yingjie, Gao, Shanyun, Jiang, Shujuan, Li, Jingjing, Zhang, Chaobo, Xu, Yanxiao, Yu, Songda, Liu, Lei, Yu, Bing, Tu, Wangyang, Zhang, Yixiang, Li, Leping
Published in Cancer research (Chicago, Ill.) (05.04.2024)
Published in Cancer research (Chicago, Ill.) (05.04.2024)
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Abstract LB031: Discovery and Characterization of HH100937, a potent and selective SOS1 inhibitor demonstrates synergistic efficacy in combination with KRAS/MAPK therapies
Xie, Qing, Li, Dongsheng, Jiang, Shujuan, Zhu, Jie, Yu, Songda, Yang, Maozhi, Cai, Yalei, Liu, Lei, Yu, Bing, Tu, Wangyang, Zhang, Yixiang, Li, Leping
Published in Cancer research (Chicago, Ill.) (05.04.2024)
Published in Cancer research (Chicago, Ill.) (05.04.2024)
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Discovery of Hydroxyamidine Derivatives as Highly Potent, Selective Indoleamine-2,3-dioxygenase 1 Inhibitors
Jin, Fangfang, Hu, Qiyue, Fei, Hongbo, Lv, Hejun, Wang, Shenglan, Gui, Bin, Zhang, Junzhen, Tu, Wangyang, Zhang, Yun, Zhang, Lei, Wan, Hong, Zhang, Limin, Hu, Bin, Yang, Fanglong, Bai, Chang, He, Feng, Zhang, Lianshan, Tao, Weikang
Published in ACS medicinal chemistry letters (11.02.2021)
Published in ACS medicinal chemistry letters (11.02.2021)
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Synthesis and biological evaluation of cyclopentyl-triazolol-pyrimidine (CPTP) based P2Y(12) antagonists
Tu, Wangyang, Fan, Jiang, Zhang, Haitang, Xu, Guoji, Liu, Zhiwei, Qu, Jian, Yang, Fanglong, Zhang, Lei, Luan, Tianyu, Yuan, Jijun, Gong, Aishen, Feng, Jun, Sun, Piaoyang, Dong, Qing
Published in Bioorganic & medicinal chemistry letters (01.01.2014)
Published in Bioorganic & medicinal chemistry letters (01.01.2014)
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Synthesis and biological evaluation of cyclopentyl-triazolol-pyrimidine (CPTP) based P2Y12 antagonists
Tu, Wangyang, Fan, Jiang, Zhang, Haitang, Xu, Guoji, Liu, Zhiwei, Qu, Jian, Yang, Fanglong, Zhang, Lei, Luan, Tianyu, Yuan, Jijun, Gong, Aishen, Feng, Jun, Sun, Piaoyang, Dong, Qing
Published in Bioorganic & medicinal chemistry letters (01.01.2014)
Published in Bioorganic & medicinal chemistry letters (01.01.2014)
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Structure-based design and synthesis of bicyclic fused-pyridines as MEK inhibitors
Lu, Hejun, Tu, Wangyang, Fei, Hongbo, Xu, Guoji, Hu, Qiyue, Zhang, Lei, Lin, Bing, Yuan, Jijun, Yin, Junzhao, Gong, Aishen, Wan, Mimi, Wang, Dan, Zhu, Xiaoyan, Feng, Jun, Wang, Qian, Sun, Piaoyang
Published in Bioorganic & medicinal chemistry letters (01.06.2014)
Published in Bioorganic & medicinal chemistry letters (01.06.2014)
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