TDP-43 interacts with amyloid-β, inhibits fibrillization, and worsens pathology in a model of Alzheimer’s disease
Shih, Yao-Hsiang, Tu, Ling-Hsien, Chang, Ting-Yu, Ganesan, Kiruthika, Chang, Wei-Wei, Chang, Pao-Sheng, Fang, Yu-Sheng, Lin, Yeh-Tung, Jin, Lee-Way, Chen, Yun-Ru
Published in Nature communications (23.11.2020)
Published in Nature communications (23.11.2020)
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Journal Article
Screening and classifying small-molecule inhibitors of amyloid formation using ion mobility spectrometry–mass spectrometry
Young, Lydia M., Saunders, Janet C., Mahood, Rachel A., Revill, Charlotte H., Foster, Richard J., Tu, Ling-Hsien, Raleigh, Daniel P., Radford, Sheena E., Ashcroft, Alison E.
Published in Nature chemistry (01.01.2015)
Published in Nature chemistry (01.01.2015)
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Journal Article
Time-resolved studies define the nature of toxic IAPP intermediates, providing insight for anti-amyloidosis therapeutics
Abedini, Andisheh, Plesner, Annette, Cao, Ping, Ridgway, Zachary, Zhang, Jinghua, Tu, Ling-Hsien, Middleton, Chris T, Chao, Brian, Sartori, Daniel J, Meng, Fanling, Wang, Hui, Wong, Amy G, Zanni, Martin T, Verchere, C Bruce, Raleigh, Daniel P, Schmidt, Ann Marie
Published in eLife (23.05.2016)
Published in eLife (23.05.2016)
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Journal Article
Islet amyloid: From fundamental biophysics to mechanisms of cytotoxicity
Cao, Ping, Marek, Peter, Noor, Harris, Patsalo, Vadim, Tu, Ling-Hsien, Wang, Hui, Abedini, Andisheh, Raleigh, Daniel P.
Published in FEBS letters (17.04.2013)
Published in FEBS letters (17.04.2013)
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Journal Article
A Free Energy Barrier Caused by the Refolding of an Oligomeric Intermediate Controls the Lag Time of Amyloid Formation by hIAPP
Serrano, Arnaldo L, Lomont, Justin P, Tu, Ling-Hsien, Raleigh, Daniel P, Zanni, Martin T
Published in Journal of the American Chemical Society (22.11.2017)
Published in Journal of the American Chemical Society (22.11.2017)
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Journal Article
The Role of Aldehyde‐Functionalized Crosslinkers on the Property of Chitosan Hydrogels
Yeh, Ying‐Yu, Tsai, Yu‐Ting, Wu, Chun‐Yu, Tu, Ling‐Hsien, Bai, Meng‐Yi, Yeh, Yi‐Cheun
Published in Macromolecular bioscience (01.05.2022)
Published in Macromolecular bioscience (01.05.2022)
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Journal Article
Beta Amyloid Oligomers with Higher Cytotoxicity have Higher Sidechain Dynamics
Yeh, Chen‐Tsen, Chang, Han‐Wen, Hsu, Wen‐Hsin, Huang, Shing‐Jong, Wu, Meng‐Hsin, Tu, Ling‐Hsien, Lee, Ming‐Che, Chan, Jerry Chun Chung
Published in Chemistry : a European journal (18.10.2023)
Published in Chemistry : a European journal (18.10.2023)
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Journal Article
Islet Amyloid Polypeptide: Structure, Function, and Pathophysiology
Schmidt, Ann Marie, Raleigh, Daniel P., Abedini, Andisheh, Wong, Amy G., Wang, Hui, Tu, Ling-Hsien, Ridgway, Zachary, Noor, Harris, Cao, Ping, Akter, Rehana, Zhang, Xiaoxue
Published in Journal of Diabetes Research (01.01.2016)
Published in Journal of Diabetes Research (01.01.2016)
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Journal Article
Piperic acid derivative as a molecular modulator to accelerate the IAPP aggregation process and alter its antimicrobial activity
Chan, Ai-Ci, Shan, Pei-Ya, Wu, Men-Hsin, Lin, Pin-Han, Tsai, Chang-Shun, Hsu, Chia-Chien, Chiu, Ting-Hsiang, Hsu, Ting-Wei, Yeh, Yi-Cheun, Lai, Yun-Ju, Liu, Wei-Min, Tu, Ling-Hsien
Published in Chemical communications (Cambridge, England) (31.08.2023)
Published in Chemical communications (Cambridge, England) (31.08.2023)
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Journal Article
The Role of Aldehyde‐Functionalized Crosslinkers on the Property of Chitosan Hydrogels
Yeh, Ying‐Yu, Tsai, Yu‐Ting, Wu, Chun‐Yu, Tu, Ling‐Hsien, Bai, Meng‐Yi, Yeh, Yi‐Cheun
Published in Macromolecular bioscience (01.10.2022)
Published in Macromolecular bioscience (01.10.2022)
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Journal Article
Aβ42 oligomers can seed the fibrillization of Aβ40 peptides
Wu, Yi‐Shan, Huang, Shing‐Jong, Wu, Meng‐Hsin, Tu, Ling‐Hsien, Lee, Ming‐Che, Chan, Jerry Chun Chung
Published in Journal of the Chinese Chemical Society (Taipei) (01.08.2022)
Published in Journal of the Chinese Chemical Society (Taipei) (01.08.2022)
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Journal Article
Dopamine-Conjugated Carbon Dots Inhibit Human Calcitonin Fibrillation
Wu, Jhe-An, Chen, Yu-Chieh, Tu, Ling-Hsien
Published in Nanomaterials (Basel, Switzerland) (30.08.2021)
Published in Nanomaterials (Basel, Switzerland) (30.08.2021)
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Journal Article
TPE conjugated islet amyloid polypeptide probe for detection of peptide oligomers
Tsai, Hsiao-Chieh, Huang, Ching-Hong, Tu, Ling-Hsien
Published in Biophysical chemistry (01.01.2024)
Published in Biophysical chemistry (01.01.2024)
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Journal Article
Protein Glycation by Glyoxal Promotes Amyloid Formation by Islet Amyloid Polypeptide
Hsu, Yi-Hsuan, Chen, Yun-Wen, Wu, Meng-Hsin, Tu, Ling-Hsien
Published in Biophysical journal (18.06.2019)
Published in Biophysical journal (18.06.2019)
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Journal Article