Single-cell RNA sequencing shows the immunosuppressive landscape and tumor heterogeneity of HBV-associated hepatocellular carcinoma
Ho, Daniel Wai-Hung, Tsui, Yu-Man, Chan, Lo-Kong, Sze, Karen Man-Fong, Zhang, Xin, Cheu, Jacinth Wing-Sum, Chiu, Yung-Tuen, Lee, Joyce Man-Fong, Chan, Albert Chi-Yan, Cheung, Elaine Tin-Yan, Yau, Derek Tsz-Wai, Chia, Nam-Hung, Lo, Irene Lai-Oi, Sham, Pak-Chung, Cheung, Tan-To, Wong, Carmen Chak-Lui, Ng, Irene Oi-Lin
Published in Nature communications (17.06.2021)
Published in Nature communications (17.06.2021)
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Journal Article
Single-cell transcriptomics reveals the landscape of intra-tumoral heterogeneity and stemness-related subpopulations in liver cancer
Ho, Daniel Wai-Hung, Tsui, Yu-Man, Sze, Karen Man-Fong, Chan, Lo-Kong, Cheung, Tan-To, Lee, Eva, Sham, Pak-Chung, Tsui, Stephen Kwok-Wing, Lee, Terence Kin-Wah, Ng, Irene Oi-Lin
Published in Cancer letters (10.09.2019)
Published in Cancer letters (10.09.2019)
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Journal Article
RALYL increases hepatocellular carcinoma stemness by sustaining the mRNA stability of TGF-β2
Wang, Xia, Wang, Jin, Tsui, Yu-Man, Shi, Chaoran, Wang, Ying, Zhang, Xin, Yan, Qian, Chen, Miao, Jiang, Chen, Yuan, Yun-Fei, Wong, Chun-Ming, Liu, Ming, Feng, Zeng-Yu, Chen, Honglin, Ng, Irene Oi Lin, Jiang, Lingxi, Guan, Xin-Yuan
Published in Nature communications (09.03.2021)
Published in Nature communications (09.03.2021)
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Journal Article
S100A10 promotes HCC development and progression via transfer in extracellular vesicles and regulating their protein cargos
Wang, Xia, Huang, Hongyang, Sze, Karen Man-Fong, Wang, Jin, Tian, Lu, Lu, Jingyi, Tsui, Yu-Man, Ma, Hoi Tang, Lee, Eva, Chen, Ao, Lee, Joyce, Wang, Ying, Yam, Judy Wai Ping, Cheung, Tan-To, Guan, Xinyuan, Ng, Irene Oi-Lin
Published in Gut (01.07.2023)
Published in Gut (01.07.2023)
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Journal Article
Hepatitis B Virus–Telomerase Reverse Transcriptase Promoter Integration Harnesses Host ELF4, Resulting in Telomerase Reverse Transcriptase Gene Transcription in Hepatocellular Carcinoma
Sze, Karen Man‐Fong, Ho, Daniel Wai‐Hung, Chiu, Yung‐Tuen, Tsui, Yu‐Man, Chan, Lo‐Kong, Lee, Joyce Man‐Fong, Chok, Kenneth Siu‐Ho, Chan, Albert Chi‐Yan, Tang, Chung‐Ngai, Tang, Victor Wai‐Lun, Lo, Irene Lai‐Oi, Yau, Derek Tsz‐Wai, Cheung, Tan‐To, Ng, Irene Oi‐Lin
Published in Hepatology (Baltimore, Md.) (01.01.2021)
Published in Hepatology (Baltimore, Md.) (01.01.2021)
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Journal Article
Antioxidant supplements promote tumor formation and growth and confer drug resistance in hepatocellular carcinoma by reducing intracellular ROS and induction of TMBIM1
Zhang, Vanilla Xin, Sze, Karen Man-Fong, Chan, Lo-Kong, Ho, Daniel Wai-Hung, Tsui, Yu-Man, Chiu, Yung-Tuen, Lee, Eva, Husain, Abdullah, Huang, Hongyang, Tian, Lu, Wong, Carmen Chak-Lui, Ng, Irene Oi-Lin
Published in Cell & bioscience (19.12.2021)
Published in Cell & bioscience (19.12.2021)
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Journal Article
Single-Cell Transcriptomics of Liver Cancer: Hype or Insights?
Zhang, Qing-yang, Ho, Daniel Wai-Hung, Tsui, Yu-Man, Ng, Irene Oi-Lin
Published in Cellular and molecular gastroenterology and hepatology (01.01.2022)
Published in Cellular and molecular gastroenterology and hepatology (01.01.2022)
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Journal Article
Multimodal Integrative Genomics and Pathology Analyses in Neoadjuvant Nivolumab Treatment for Intermediate and Locally Advanced Hepatocellular Carcinoma
Cheung, Tan-To, Ho, Daniel Wai-Hung, Lyu, Shirley Xueying, Zhang, Qingyang, Tsui, Yu-Man, Yu, Tiffany Ching-Yun, Sze, Karen Man-Fong, Lee, Joyce Man-Fong, Lau, Vince Wing-hang, Chu, Edward Yin-Lun, Tsang, Simon Hing-Yin, She, Wong-Hoi, Leung, Roland Ching-Yu, Yau, Thomas Chung-Cheung, Ng, Irene Oi-Lin
Published in Liver cancer (Basel ) (01.02.2024)
Published in Liver cancer (Basel ) (01.02.2024)
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Journal Article
Cellular heterogeneity and plasticity in liver cancer
Chan, Lo-Kong, Tsui, Yu-Man, Ho, Daniel Wai-Hung, Ng, Irene Oi-Lin
Published in Seminars in cancer biology (01.07.2022)
Published in Seminars in cancer biology (01.07.2022)
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Journal Article
SENP1 promotes hypoxia-induced cancer stemness by HIF-1α deSUMOylation and SENP1/HIF-1α positive feedback loop
Cui, Chun-Ping, Wong, Carmen Chak-Lui, Kai, Alan Ka-Lun, Ho, Daniel Wai-Hung, Lau, Eunice Yuen-Ting, Tsui, Yu-Man, Chan, Lo-Kong, Cheung, Tan-To, Chok, Kenneth Siu-Ho, Chan, Albert C Y, Lo, Regina Cheuk-Lam, Lee, Joyce Man-Fong, Lee, Terence Kin-Wah, Ng, Irene Oi Lin
Published in Gut (01.12.2017)
Published in Gut (01.12.2017)
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Journal Article
Ephrin-A3/EphA2 axis regulates cellular metabolic plasticity to enhance cancer stemness in hypoxic hepatocellular carcinoma
Husain, Abdullah, Chiu, Yung-Tuen, Sze, Karen Man-Fong, Ho, Daniel Wai-Hung, Tsui, Yu-Man, Suarez, Eliana Mary Senires, Zhang, Vanilla Xin, Chan, Lo-Kong, Lee, Eva, Lee, Joyce Man-Fong, Cheung, Tan-To, Wong, Carmen Chak-Lui, Chung, Clive Yik-Sham, Ng, Irene Oi-Lin
Published in Journal of hepatology (01.08.2022)
Published in Journal of hepatology (01.08.2022)
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Journal Article
LANCL1, a cell surface protein, promotes liver tumor initiation through FAM49B-Rac1 axis to suppress oxidative stress
Huang, Hongyang, Tsui, Yu-Man, Ho, Daniel Wai-Hung, Chung, Clive Yik-Sham, Sze, Karen Man-Fong, Lee, Eva, Cheung, Gary Cheuk-Hang, Zhang, Vanilla Xin, Wang, Xia, Lyu, Xueying, Ng, Irene Oi-Lin
Published in Hepatology (Baltimore, Md.) (01.02.2024)
Published in Hepatology (Baltimore, Md.) (01.02.2024)
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Journal Article
Resolution of Optimal Mitochondrial and Nuclear DNA Enrichment in Target-Panel Sequencing and Physiological Mitochondrial DNA Copy Number Estimation in Liver Cancer and Non-Liver Cancer Subjects
Lyu, Xue-Ying, Tsui, Yu-Man, Tam, Ivan Ka-Kit, Li, Po-Man, Cheung, Gary Cheuk-Hang, Lee, Joyce Man-Fong, Ng, Irene Oi-Lin, Ho, Daniel Wai-Hung
Published in Cancers (29.08.2024)
Published in Cancers (29.08.2024)
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Journal Article
Reciprocal interactions between malignant cells and macrophages enhance cancer stemness and M2 polarization in HBV-associated hepatocellular carcinoma
Zhang, Qingyang, Tsui, Yu-Man, Zhang, Vanilla Xin, Lu, Anna Jingyi, Lee, Joyce Man-Fong, Lee, Eva, Cheung, Gary Cheuk-Hang, Li, Po-Man, Cheung, Elaine Tin-Yan, Chia, Nam-Hung, Lo, Irene Lai-Oi, Chan, Albert Chi-Yan, Cheung, Tan-To, Ng, Irene Oi-Lin, Ho, Daniel Wai-Hung
Published in Theranostics (2024)
Published in Theranostics (2024)
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Journal Article
PFKFB4 Drives the Oncogenicity in TP53-Mutated Hepatocellular Carcinoma in a Phosphatase-Dependent Manner
Kam, Charles Shing, Ho, Daniel Wai-Hung, Ming, Vanessa Sheung-In, Tian, Lu, Sze, Karen Man-Fong, Zhang, Vanilla Xin, Tsui, Yu-Man, Husain, Abdullah, Lee, Joyce Man-Fong, Wong, Carmen Chak-Lui, Chan, Albert Chi-Yan, Cheung, Tan-To, Chan, Lo-Kong, Ng, Irene Oi-Lin
Published in Cellular and molecular gastroenterology and hepatology (01.01.2023)
Published in Cellular and molecular gastroenterology and hepatology (01.01.2023)
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Journal Article
Dishevelled-3 phosphorylation is governed by HIPK2/PP1Cα/ITCH axis and the non-phosphorylated form promotes cancer stemness via LGR5 in hepatocellular carcinoma
Tsui, Yu-Man, Sze, Karen Man-Fong, Tung, Edmund Kwok-Kwan, Ho, Daniel Wai-Hung, Lee, Terence Kin-Wah, Ng, Irene Oi-Lin
Published in Oncotarget (13.06.2017)
Published in Oncotarget (13.06.2017)
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