Psoriasis: a mixed autoimmune and autoinflammatory disease
Liang, Yun, Sarkar, Mrinal K, Tsoi, Lam C, Gudjonsson, Johann E
Published in Current opinion in immunology (01.12.2017)
Published in Current opinion in immunology (01.12.2017)
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Single cell and spatial sequencing define processes by which keratinocytes and fibroblasts amplify inflammatory responses in psoriasis
Ma, Feiyang, Plazyo, Olesya, Billi, Allison C., Tsoi, Lam C., Xing, Xianying, Wasikowski, Rachael, Gharaee-Kermani, Mehrnaz, Hile, Grace, Jiang, Yanyun, Harms, Paul W., Xing, Enze, Kirma, Joseph, Xi, Jingyue, Hsu, Jer-En, Sarkar, Mrinal K., Chung, Yutein, Di Domizio, Jeremy, Gilliet, Michel, Ward, Nicole L., Maverakis, Emanual, Klechevsky, Eynav, Voorhees, John J., Elder, James T., Lee, Jun Hee, Kahlenberg, J. Michelle, Pellegrini, Matteo, Modlin, Robert L., Gudjonsson, Johann E.
Published in Nature communications (12.06.2023)
Published in Nature communications (12.06.2023)
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Journal Article
Novel insights into atopic dermatitis
Schuler, Charles F., Billi, Allison C., Maverakis, Emanual, Tsoi, Lam C., Gudjonsson, Johann E.
Published in Journal of allergy and clinical immunology (01.05.2023)
Published in Journal of allergy and clinical immunology (01.05.2023)
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Journal Article
Analysis of long non-coding RNAs highlights tissue-specific expression patterns and epigenetic profiles in normal and psoriatic skin
Tsoi, Lam C, Iyer, Matthew K, Stuart, Philip E, Swindell, William R, Gudjonsson, Johann E, Tejasvi, Trilokraj, Sarkar, Mrinal K, Li, Bingshan, Ding, Jun, Voorhees, John J, Kang, Hyun M, Nair, Rajan P, Chinnaiyan, Arul M, Abecasis, Goncalo R, Elder, James T
Published in Genome Biology (30.01.2015)
Published in Genome Biology (30.01.2015)
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Atopic Dermatitis Is an IL-13–Dominant Disease with Greater Molecular Heterogeneity Compared to Psoriasis
Tsoi, Lam C., Rodriguez, Elke, Degenhardt, Frauke, Baurecht, Hansjörg, Wehkamp, Ulrike, Volks, Natalie, Szymczak, Silke, Swindell, William R., Sarkar, Mrinal K., Raja, Kalpana, Shao, Shuai, Patrick, Matthew, Gao, Yilin, Uppala, Ranjitha, Perez White, Bethany E, Getsios, Spiro, Harms, Paul W., Maverakis, Emanual, Elder, James T., Franke, Andre, Gudjonsson, Johann E., Weidinger, Stephan
Published in Journal of investigative dermatology (01.07.2019)
Published in Journal of investigative dermatology (01.07.2019)
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Second-Strand Synthesis-Based Massively Parallel scRNA-Seq Reveals Cellular States and Molecular Features of Human Inflammatory Skin Pathologies
Hughes, Travis K., Wadsworth, Marc H., Gierahn, Todd M., Do, Tran, Weiss, David, Andrade, Priscila R., Ma, Feiyang, de Andrade Silva, Bruno J., Shao, Shuai, Tsoi, Lam C., Ordovas-Montanes, Jose, Gudjonsson, Johann E., Modlin, Robert L., Love, J. Christopher, Shalek, Alex K.
Published in Immunity (Cambridge, Mass.) (13.10.2020)
Published in Immunity (Cambridge, Mass.) (13.10.2020)
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Journal Article
GRHL3 binding and enhancers rearrange as epidermal keratinocytes transition between functional states
Klein, Rachel Herndon, Lin, Ziguang, Hopkin, Amelia Soto, Gordon, William, Tsoi, Lam C, Liang, Yun, Gudjonsson, Johann E, Andersen, Bogi
Published in PLoS genetics (26.04.2017)
Published in PLoS genetics (26.04.2017)
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Assessing Mitochondrial DNA Variation and Copy Number in Lymphocytes of ~2,000 Sardinians Using Tailored Sequencing Analysis Tools
Ding, Jun, Sidore, Carlo, Butler, Thomas J, Wing, Mary Kate, Qian, Yong, Meirelles, Osorio, Busonero, Fabio, Tsoi, Lam C, Maschio, Andrea, Angius, Andrea, Kang, Hyun Min, Nagaraja, Ramaiah, Cucca, Francesco, Abecasis, Gonçalo R, Schlessinger, David
Published in PLoS genetics (01.07.2015)
Published in PLoS genetics (01.07.2015)
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Associations between COVID-19 and skin conditions identified through epidemiology and genomic studies
Patrick, Matthew T., Zhang, Haihan, Wasikowski, Rachael, Prens, Errol P., Weidinger, Stephan, Gudjonsson, Johann E., Elder, James T., He, Kevin, Tsoi, Lam C.
Published in Journal of allergy and clinical immunology (01.03.2021)
Published in Journal of allergy and clinical immunology (01.03.2021)
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Journal Article
Shared genetic risk factors and causal association between psoriasis and coronary artery disease
Patrick, Matthew T., Li, Qinmengge, Wasikowski, Rachael, Mehta, Nehal, Gudjonsson, Johann E., Elder, James T., Zhou, Xiang, Tsoi, Lam C.
Published in Nature communications (02.11.2022)
Published in Nature communications (02.11.2022)
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Fine Mapping Major Histocompatibility Complex Associations in Psoriasis and Its Clinical Subtypes
Okada, Yukinori, Han, Buhm, Tsoi, Lam C., Stuart, Philip E., Ellinghaus, Eva, Tejasvi, Trilokraj, Chandran, Vinod, Pellett, Fawnda, Pollock, Remy, Bowcock, Anne M., Krueger, Gerald G., Weichenthal, Michael, Voorhees, John J., Rahman, Proton, Gregersen, Peter K., Franke, Andre, Nair, Rajan P., Abecasis, Gonçalo R., Gladman, Dafna D., Elder, James T., de Bakker, Paul I.W., Raychaudhuri, Soumya
Published in American journal of human genetics (07.08.2014)
Published in American journal of human genetics (07.08.2014)
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Evidence of a causal relationship between body mass index and psoriasis: A mendelian randomization study
Budu-Aggrey, Ashley, Brumpton, Ben, Tyrrell, Jess, Watkins, Sarah, Modalsli, Ellen H, Celis-Morales, Carlos, Ferguson, Lyn D, Vie, Gunnhild Åberge, Palmer, Tom, Fritsche, Lars G, Løset, Mari, Nielsen, Jonas Bille, Zhou, Wei, Tsoi, Lam C, Wood, Andrew R, Jones, Samuel E, Beaumont, Robin, Saunes, Marit, Romundstad, Pål Richard, Siebert, Stefan, McInnes, Iain B, Elder, James T, Davey Smith, George, Frayling, Timothy M, Åsvold, Bjørn Olav, Brown, Sara J, Sattar, Naveed, Paternoster, Lavinia
Published in PLoS medicine (31.01.2019)
Published in PLoS medicine (31.01.2019)
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Inhibition of macrophage histone demethylase JMJD3 protects against abdominal aortic aneurysms
Davis, Frank M, Tsoi, Lam C, Melvin, William J, denDekker, Aaron, Wasikowski, Rachael, Joshi, Amrita D, Wolf, Sonya, Obi, Andrea T, Billi, Allison C, Xing, Xianying, Audu, Christopher, Moore, Bethany B, Kunkel, Steven L, Daugherty, Alan, Lu, Hong S, Gudjonsson, Johann E, Gallagher, Katherine A
Published in The Journal of experimental medicine (07.06.2021)
Published in The Journal of experimental medicine (07.06.2021)
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Transcriptomic characterization of prurigo nodularis and the therapeutic response to nemolizumab
Tsoi, Lam C., Hacini-Rachinel, Feriel, Fogel, Paul, Rousseau, Francois, Xing, Xianying, Patrick, Matthew T., Billi, Allison C., Berthier, Celine C., Kahlenberg, J. Michelle, Lazzari, Anne, Wiegmann, Henning, Ständer, Sonja, Piketty, Christophe, Julia, Valerie, Krishnaswamy, Jayendra Kumar, Gudjonsson, Johann E.
Published in Journal of allergy and clinical immunology (01.04.2022)
Published in Journal of allergy and clinical immunology (01.04.2022)
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Neutrophil Extracellular Traps Induce Human Th17 Cells: Effect of Psoriasis-Associated TRAF3IP2 Genotype
Lambert, Sylviane, Hambro, Caely A., Johnston, Andrew, Stuart, Philip E., Tsoi, Lam C., Nair, Rajan P., Elder, James T.
Published in Journal of investigative dermatology (01.06.2019)
Published in Journal of investigative dermatology (01.06.2019)
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Journal Article
Cytokinocytes: the diverse contribution of keratinocytes to immune responses in skin
Jiang, Yanyun, Tsoi, Lam C, Billi, Allison C, Ward, Nicole L, Harms, Paul W, Zeng, Chang, Maverakis, Emanual, Kahlenberg, J Michelle, Gudjonsson, Johann E
Published in JCI insight (15.10.2020)
Published in JCI insight (15.10.2020)
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