Dose-dependent antithrombotic activity of an orally active tissue factor/factor VIIa inhibitor without concomitant enhancement of bleeding propensity
Zbinden, Katrin Groebke, Banner, David W., Hilpert, Kurt, Himber, Jacques, Lavé, Thierry, Riederer, Markus A., Stahl, Martin, Tschopp, Thomas B., Obst-Sander, Ulrike
Published in Bioorganic & medicinal chemistry (01.08.2006)
Published in Bioorganic & medicinal chemistry (01.08.2006)
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Journal Article
Selective and orally bioavailable phenylglycine tissue factor/factor VIIa inhibitors
Zbinden, Katrin Groebke, Obst-Sander, Ulrike, Hilpert, Kurt, Kühne, Holger, Banner, David W., Böhm, Hans-Joachim, Stahl, Martin, Ackermann, Jean, Alig, Leo, Weber, Lutz, Wessel, Hans Peter, Riederer, Markus A., Tschopp, Thomas B., Lavé, Thierry
Published in Bioorganic & medicinal chemistry letters (01.12.2005)
Published in Bioorganic & medicinal chemistry letters (01.12.2005)
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Journal Article
Can the calculation of ligand binding free energies be improved with continuum solvent electrostatics and an ideal‐gas entropy correction?
Schwarzl, Sonja M., Tschopp, Thomas B., Smith, Jeremy C., Fischer, Stefan
Published in Journal of computational chemistry (01.09.2002)
Published in Journal of computational chemistry (01.09.2002)
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Journal Article
Design of selective phenylglycine amide tissue factor/factor VIIa inhibitors
Groebke Zbinden, Katrin, Banner, David W., Ackermann, Jean, D’Arcy, Allan, Kirchhofer, Daniel, Ji, Yu-Hua, Tschopp, Thomas B., Wallbaum, Sabine, Weber, Lutz
Published in Bioorganic & medicinal chemistry letters (01.02.2005)
Published in Bioorganic & medicinal chemistry letters (01.02.2005)
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Journal Article
Design and Synthesis of Potent and Highly Selective Thrombin Inhibitors
Hilpert, Kurt, Ackermann, Jean, Banner, David W., Gast, Alain, Gubernator, Klaus, Hadvary, Paul, Labler, Ludvik, Mueller, Klaus, Schmid, Gerard
Published in Journal of medicinal chemistry (01.11.1994)
Published in Journal of medicinal chemistry (01.11.1994)
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Journal Article
GUANIDINS
WESSEL, HANS P, GUBERNATOR, KLAUS, LABLER, LUDVIK, ACKERMANN, JEAN, HADVARY, PAUL, MUELLER, KLAUS PROF, SCHMID, GERARD, WIRZ, BEAT, HILPERT, KURT, BANNER, DAVID, TSCHOPP; THOMAS B
Year of Publication 01.09.1999
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Year of Publication 01.09.1999
Patent
Impaired interaction (adhesion-aggregation) of platelets with the subendothelium in storage-pool disease and after aspirin ingestion. A comparison with von Willebrand's disease
Weiss, H J, Tschopp, T B, Baumgartner, H R
Published in The New England journal of medicine (25.09.1975)
Published in The New England journal of medicine (25.09.1975)
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Journal Article
Endothelial cells stimulated with tumor necrosis factor-alpha express varying amounts of tissue factor resulting in inhomogenous fibrin deposition in a native blood flow system. Effects of thrombin inhibitors
Kirchhofer, D, Tschopp, T B, Hadváry, P, Baumgartner, H R
Published in The Journal of clinical investigation (01.05.1994)
Published in The Journal of clinical investigation (01.05.1994)
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Journal Article
Role of Collagen-Adherent Platelets in Mediating Fibrin Formation in Flowing Whole Blood
Kirchhofer, Daniel, Tschopp, Thomas B., Steiner, Beat, Baumgartner, Hans R.
Published in Blood (15.11.1995)
Published in Blood (15.11.1995)
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Journal Article
Activated clotting time as an appropriate test to compare heparin and direct thrombin inhibitor such as hirudin or Ro 46-6240 in experimental arterial thrombosis
Carteaux, Jean Pierre, Gast, Alain, Tschopp, Thomas B, Roux, Sebastien
Published in Circulation (New York, N.Y.) (01.03.1995)
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Published in Circulation (New York, N.Y.) (01.03.1995)
Journal Article
Relationship between tissue factor expression and deposition of fibrin, platelets, and leukocytes on cultured endothelial cells under venous blood flow conditions
KIRCHHOFER, D, SAKARIASSEN, K. S, CLOZEL, M, TSCHOPP, T. B, HADVARY, P, NEMERSON, Y, BAUMGARTNER, H. R
Published in Blood (15.04.1993)
Published in Blood (15.04.1993)
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Journal Article
The Development of Potent and Highly Selective Thrombin Inhibitors
Hilpert, Kurt, Ackermann, Jean, Banner, David W., Gast, Alain, Gubernator, Klaus, Schmid, Gérard, Tschopp, Thomas B., van de Waterbeemd, Han
Published in European journal of medicinal chemistry (1995)
Published in European journal of medicinal chemistry (1995)
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Journal Article
Conference Proceeding
Decreased adhesion of giant (Bernard-Soulier) platelets to subendothelium: Further implications on the role of the von Willebrand factor in hemostasis
Weiss, Harvey J., Tschopp, Thomas B., Baumgartner, Hans R., Sussman, Ira I., Johnson, Margaret M., Egan, John J.
Published in The American journal of medicine (01.01.1974)
Published in The American journal of medicine (01.01.1974)
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